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Dollar change +0.07
Percentage change 0.39	%

Peers: VRTX REGN AMGN GILD BIIB BMRN INCY EXEL NBIX RGEN

| Held by: VTI VXF IBB IWC AVSC DFAS DFAC BBC DFUS DFAU

Index	-	P/E	-	EPS (ttm)	-8.20	Insider Own	42.66%	Shs Outstand	14.86M	Perf Week	22.29%
Market Cap	334.81M	Forward P/E	-	EPS next Y	-4.92	Insider Trans	18.38%	Shs Float	10.70M	Perf Month	-25.13%
Income	-49.57M	PEG	-	EPS next Q	-1.09	Inst Own	39.57%	Short Float	10.33%	Perf Quarter	-52.79%
Sales	0.00M	P/S	-	EPS this Y	33.16%	Inst Trans	5.62%	Short Ratio	2.98	Perf Half Y	-42.79%
Book/sh	9.48	P/B	1.89	EPS next Y	-7.89%	ROA	-39.03%	Short Interest	1.10M	Perf Year	17.72%
Cash/sh	7.57	P/C	2.37	EPS next 5Y	2.49%	ROE	-42.09%	52W Range	13.70 - 61.07	Perf YTD	-61.14%
Dividend Est.	-	P/FCF	-	EPS past 5Y	26.54%	ROI	-35.08%	52W High	-70.62%	Beta	1.63
Dividend TTM	-	Quick Ratio	12.65	Sales past 5Y	0.00%	Gross Margin	-	52W Low	30.95%	ATR (14)	2.04
Dividend Ex-Date	-	Current Ratio	12.65	EPS Y/Y TTM	-343.40%	Oper. Margin	-	RSI (14)	42.55	Volatility	11.09% 10.34%
Employees	51	Debt/Eq	0.02	Sales Y/Y TTM	-	Profit Margin	-	Recom	1.00	Target Price	82.00
Option/Short	Yes / Yes	LT Debt/Eq	0.00	EPS Q/Q	64.57%	Payout	-	Rel Volume	0.38	Prev Close	17.87
Sales Surprise	-	EPS Surprise	39.42%	Sales Q/Q	-	Earnings	Mar 20 AMC	Avg Volume	370.39K	Price	17.94
SMA20	-1.66%	SMA50	-27.77%	SMA200	-40.51%	Trades		Volume	142,190	Change	0.39%

Date	Action	Analyst	Rating Change	Price Target Change
Nov-20-24	Initiated	Raymond James	Outperform	$65
Aug-22-24	Initiated	Wells Fargo	Overweight	$55
Jun-26-24	Initiated	Piper Sandler	Overweight
Jun-24-24	Initiated	TD Cowen	Buy
Dec-18-23	Downgrade	Mizuho	Buy → Neutral
Jan-05-22	Downgrade	BTIG Research	Buy → Neutral
Nov-19-21	Downgrade	Morgan Stanley	Overweight → Equal-Weight	$24 → $7
Jun-15-21	Initiated	BTIG Research	Buy	$23
May-27-21	Initiated	Needham	Buy	$28
Mar-09-21	Initiated	Barclays	Overweight	$23
Mar-02-21	Initiated	Stifel	Hold	$14
Nov-11-20	Initiated	Berenberg	Buy
Mar-31-20	Downgrade	H.C. Wainwright	Buy → Neutral	$13
Jun-27-19	Initiated	Mizuho	Buy	$28
Apr-05-19	Initiated	Janney	Buy
Oct-10-18	Initiated	Guggenheim	Buy
Oct-02-18	Reiterated	H.C. Wainwright	Buy	$47 → $40
Sep-17-18	Initiated	H.C. Wainwright	Buy	$47
Jul-16-18	Initiated	Wells Fargo	Outperform	$40
Jul-16-18	Initiated	Wedbush	Outperform	$38

Show Previous Ratings

Apr-15-25 08:00AM	Tectonic Therapeutic to Present Phase 1b Data for TX45 at European Society of Cardiology Heart Failure 2025 (GlobeNewswire)
Mar-20-25 04:01PM	Tectonic Therapeutic Announces Fourth Quarter and Full Year 2024 Financial Results and Recent Business Highlights (GlobeNewswire)
Mar-04-25 08:26PM	Is Tectonic Therapeutic, Inc. (TECX) Among Stocks With At Least $20 Million In Insider Spending Recently? (Insider Monkey)
Feb-20-25 08:00AM	Tectonic Therapeutic to Participate in March Investor Conferences (GlobeNewswire)
Feb-03-25 06:30AM	Tectonic Announces $185 Million Private Placement (GlobeNewswire) -6.52%
06:30AM	Loading…
Jan-30-25 06:30AM	Tectonic Therapeutic Announces Positive Interim Data from Phase 1b Trial for TX45 in Patients with Group 2 Pulmonary Hypertension in HFpEF (GlobeNewswire) +113.22%
Dec-03-24 04:01PM	Tectonic Therapeutic to Host KOL Event on the Unmet Need in Group 2 PH-HFpEF and TX45 as a Potential Treatment on Thursday, December 12, 2024 (GlobeNewswire)
Nov-26-24 04:01PM	Tectonic Therapeutic To Present on December 3rd, 2024 at the Piper Sandler Healthcare Conference (GlobeNewswire)
Nov-12-24 11:01PM	Tectonic Therapeutic Inc. Reports Q3 2024 Results (TipRanks)
Nov-11-24 05:00AM	Tectonic Therapeutic Announces Positive Phase 1a Results in AHA 2024 Presentation for TX45, a Long-acting, Fc-Relaxin Fusion Protein (GlobeNewswire)
Nov-07-24 04:01PM	Tectonic Therapeutic Announces Third Quarter 2024 Financial Results and Recent Business Highlights (GlobeNewswire)
Oct-22-24 04:01PM	Tectonic Therapeutic to Present Phase 1a Data at AHA 2024 (GlobeNewswire)
Sep-19-24 04:01PM	Tectonic Therapeutic Announces Favorable Phase 1a Safety, Tolerability and PK/PD Results for Lead Program TX45 (GlobeNewswire)
Aug-20-24 04:01PM	Tectonic Therapeutic to Participate in September Investor Conferences (GlobeNewswire)
Aug-14-24 04:01PM	Tectonic Therapeutic Announces Second Quarter 2024 Financial Results and Recent Business Highlights (GlobeNewswire) +5.23%
04:01PM	Loading…
Jul-30-24 04:01PM	Tectonic Therapeutic Announces US IND Clearance for Lead Program, TX45 (GlobeNewswire)
Jun-20-24 04:01PM	Tectonic Therapeutic Announces Closing of Merger with AVROBIO as well as Concurrent Private Placement of $130.7 Million (Business Wire)
09:47AM	PLTR Stock: Palantir Bags New Partnership With ARPA-H for AI/ML (InvestorPlace)
08:26AM	Why Is Avrobio (AVRO) Stock Moving Today? (InvestorPlace)
07:28AM	Today's Biggest Pre-Market Stock Movers: 10 Top Gainers and Losers on Wednesday (InvestorPlace)
May-15-24 11:27AM	Avrobio Insider Bought Shares Worth $971,493, According to a Recent SEC Filing (MT Newswires) +6.20%
May-13-24 09:53AM	AVRO Stock Earnings: Avrobio Beats EPS for Q1 2024 (InvestorPlace) +9.76%
Feb-27-24 10:50AM	Kuehn Law Encourages CHRD, AVRO, KAMN, and CTLT Investors to Contact Law Firm (PR Newswire)
Feb-01-24 02:25PM	Kuehn Law Encourages ICVX, CSTR, AVRO, and CALB Investors to Contact Law Firm (PR Newswire)
Jan-31-24 10:40AM	SHAREHOLDER NOTICE: Halper Sadeh LLC Investigates TAST, AVRO, CALB (GlobeNewswire) +9.57%
06:42AM	Avrobios road ends in reverse merger with Tim Springer-backed startup (BioPharma Dive)
Jan-30-24 02:52PM	Avrobio's corporate tremor attracts Tectonic for reverse merger (FierceBiotech.com) -16.06%
02:38PM	SHAREHOLDER NOTICE: Halper Sadeh LLC Investigates AVRO, CALB, BCAL (PR Newswire)
08:00AM	AVROBIO and Tectonic Therapeutic Announce Merger (Business Wire)
Nov-08-23 09:40AM	Is AVROBIO (AVRO) Stock Outpacing Its Medical Peers This Year? (Zacks)
09:40AM	Loading…
Oct-23-23 09:40AM	Is AVROBIO (AVRO) Outperforming Other Medical Stocks This Year? (Zacks)
Oct-06-23 09:40AM	Has AVROBIO (AVRO) Outpaced Other Medical Stocks This Year? (Zacks)
Jul-13-23 07:08AM	AVROBIO (AVRO) to Explore Strategic Options, Stock Rises 46% (Zacks)
Jul-12-23 07:00AM	AVROBIO to Explore Strategic Alternatives (Business Wire) +45.96%
Jun-12-23 07:00AM	AVROBIO Completes Sale of Cystinosis Gene Therapy Program for $87.5 Million (Business Wire)
May-22-23 07:00AM	AVROBIO Announces Agreement to Sell Cystinosis Gene Therapy Program for $87.5 Million (Business Wire) +69.01%
May-18-23 02:53PM	Avrobio Touts Positive Data Gene Therapy Trial For Cystinosis, Showing Treatment Durability Of Up To 36 Months (Benzinga) +45.33%
07:00AM	AVROBIO Announces Positive Data from Phase 1/2 Clinical Trial of Investigational Gene Therapy for Cystinosis at the ASGCT 26th Annual Meeting (Business Wire)
May-11-23 07:00AM	AVROBIO Reports First Quarter 2023 Financial Results and Provides Business Update (Business Wire)
May-01-23 07:30AM	AVROBIO Announces Leadership Transition (Business Wire) -15.99%
Mar-23-23 07:00AM	AVROBIO Reports Fourth Quarter and Fiscal Year 2022 Financial Results and Provides Business Update (Business Wire) -27.64%
Mar-03-23 07:00AM	AVROBIO to Participate in Cowens 43rd Annual Health Care Conference (Business Wire)
Feb-09-23 07:00AM	AVROBIO to Present Clinical and Preclinical Data from Lysosomal Disorder Gene Therapy Pipeline at WORLDSymposium 2023 (Business Wire) +7.69%
Jan-05-23 07:00AM	AVROBIO Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) (Business Wire)
Dec-07-22 07:30AM	AVROBIO Announces New Positive Clinical Data and Outlines Clinical Development Plan Following Regulatory Discussions for its Gaucher Disease Gene Therapy (Business Wire) -6.96%
Nov-17-22 07:00AM	AVROBIO to Share Comprehensive Gaucher Disease Program Update (Business Wire) +5.40%
Nov-08-22 07:00AM	AVROBIO Reports Third Quarter 2022 Financial Results and Provides Business Update (Business Wire)
Nov-07-22 07:00AM	AVROBIO to Participate in the Sixth Annual Barclays Gene Editing/Therapy Summit (Business Wire)
Nov-03-22 07:00AM	AVROBIO Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (Business Wire)
Oct-27-22 07:00AM	AVROBIO Receives Rare Pediatric Disease Designation from the U.S. FDA for First-in-Class Gene Therapy for Gaucher Disease (Business Wire)
Oct-25-22 07:00AM	AVROBIO Announces Completion of Patient Dosing in First Gene Therapy Clinical Trial for Cystinosis (Business Wire)
Oct-18-22 07:00AM	AVROBIO Granted ILAP Designation from U.K. MHRA for First-in-Class Gene Therapy for Gaucher Disease (Business Wire) +12.37%
Oct-11-22 07:00AM	AVROBIO Reports Favorable Data on Use of Combined State-of-the-art In Vitro Cell-based Assays to Identify Potential Genotoxicity Risk of Integrating Vectors During Preclinical Development (Business Wire)
Oct-06-22 07:00AM	AVROBIO Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (Business Wire)
Sep-27-22 07:00AM	AVROBIO to Present New Preclinical Data on Vector Safety at ESGCT Annual Congress (Business Wire) -10.23%
Sep-20-22 07:00AM	AVROBIO Receives Rare Pediatric Disease Designation from U.S. Food and Drug Administration (FDA) for First Gene Therapy in Development for Cystinosis (Business Wire)
Sep-14-22 07:28AM	AVROBIO Announces Neuronopathic Mucopolysaccharidosis Type II (nMPS-II) or Hunter Syndrome Clinical Trial Application (CTA) Accepted by U.K. Regulatory Agency to Initiate Pediatric Phase 1/2 Gene Therapy Trial (Business Wire)
Sep-08-22 07:00AM	AVROBIO Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (Business Wire)
Aug-31-22 07:00AM	AVROBIO to Participate in Four Upcoming Investor Conferences in September (Business Wire)
Aug-09-22 07:00AM	AVROBIO Reports Second Quarter 2022 Financial Results and Provides Business Update (Business Wire)
Aug-04-22 07:00AM	AVROBIO Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (Business Wire)
Aug-01-22 07:00AM	AVROBIO to Participate in Two Upcoming Investor Conferences in August (Business Wire)
Jul-13-22 07:00AM	AVROBIO Receives Orphan Drug Designation from the U.S. Food and Drug Administration for AVR-RD-05, a Gene Therapy for Mucopolysaccharidosis Type II (MPSII) or Hunter Syndrome (Business Wire)
Jul-06-22 07:00AM	AVROBIO Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (Business Wire) +6.47%
May-18-22 03:12PM	AVROBIO (AVRO) Stock Up on Upbeat Data From Cystinosis Study (Zacks) -8.57%
12:41PM	Avrobio's Pompe Disease Gene Therapy Shows Efficacy, Safety In Preclinical Study (Benzinga)
07:00AM	AVROBIO Announces Preclinical Gene Therapy Data for Pompe Disease at American Society of Gene and Cell Therapy (ASGCT) Annual Meeting (Business Wire)
May-17-22 12:15PM	AVROBIO Shares Jumps On Encouraging Data From Early-Stage Gene Therapy Study (Benzinga)
07:00AM	AVROBIO Reports Positive Data From Phase 1/2 Clinical Trial of Investigational Gene Therapy for Cystinosis, Including New Interim Data on Neurocognitive Measures (Business Wire)
May-16-22 07:00AM	AVROBIO to Present at the H.C. Wainwright Global Investment Conference (Business Wire)
May-10-22 07:00AM	AVROBIO Reports First Quarter 2022 Financial Results and Provides Business Update (Business Wire)
May-06-22 07:00AM	AVROBIO Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (Business Wire)
May-03-22 07:00AM	AVROBIO to Present New Clinical and Preclinical Data at the ASGCT 25th Annual Meeting (Business Wire)
Apr-06-22 12:36PM	bluebird (BLUE) Undertakes Restructuring Moves to Curb Cash Burn (Zacks)
07:00AM	AVROBIO Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) (Business Wire)
Apr-05-22 12:54PM	Corcept (CORT) Completes Enrolment in Mid-Stage Weight Gain Study (Zacks)
07:00AM	AVROBIO to Present at the 21st Annual Needham Virtual Healthcare Conference (Business Wire)
Mar-17-22 07:00AM	AVROBIO Reports Fourth Quarter and Fiscal Year 2021 Financial Results and Provides Business Update (Business Wire) +8.33%
Mar-01-22 07:00AM	AVROBIO to Present at Two Upcoming Investor Conferences in March (Business Wire)
Feb-21-22 12:14PM	2 Net Current Asset Value Stocks to Consider (GuruFocus.com)
Feb-09-22 12:55PM	After Fabry Trial Setback, Avrobio Hopes Rebound With Lysosomal Storage Disorder Data (Benzinga) -6.25%
07:00AM	AVROBIO Reports Interim Data from Phase 1/2 Clinical Trial of Investigational Gene Therapy for Cystinosis (Business Wire)
Feb-04-22 07:00AM	AVROBIO Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (Business Wire)
Feb-03-22 10:00AM	Here's Why AVROBIO, Inc. (AVRO) is Poised for a Turnaround After Losing 19.7% in 4 Weeks (Zacks)
Feb-01-22 07:00AM	AVROBIO Announces the Appointment of Sean OBryan as Chief Regulatory Officer (Business Wire)
Jan-28-22 07:00AM	AVROBIO to Present at Cowens 2nd Annual Genetic Medicines Summit (Business Wire) +6.32%
Jan-27-22 07:00AM	AVROBIO to Present New Data from Phase 1/2 Clinical Trial in Cystinosis at WORLDSymposium 2022 (Business Wire) -5.43%
Jan-25-22 10:00AM	Bears are Losing Control Over AVROBIO, Inc. (AVRO), Here's Why It's a 'Buy' Now (Zacks)
Jan-07-22 10:00AM	Here's Why AVROBIO, Inc. (AVRO) is Poised for a Turnaround After Losing 44.1% in 4 Weeks (Zacks)
Jan-06-22 07:00AM	AVROBIO Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (Business Wire)
Jan-04-22 02:28PM	AvroBio shares plunge after company halts development of Fabry drug (American City Business Journals) -36.63%
09:07AM	Wedbush Says Avrobio Shares Still Undervalued Despite 33% Fall (Investing.com)
07:57AM	Why Avrobio's Shares Are Plunging Today (Benzinga)
07:00AM	AVROBIO Reprioritizes Pipeline Programs (Business Wire)
Dec-07-21 07:00AM	AVROBIO Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (Business Wire) +7.67%
Dec-04-21 06:25AM	Is AVROBIO (NASDAQ:AVRO) In A Good Position To Deliver On Growth Plans? (Simply Wall St.)
Nov-24-21 07:00AM	AVROBIO Presents Clinician Experience with FAB-GT Clinical Trial and Updated Safety Data for Investigational Gene Therapies in Fabry Disease and Gaucher Disease Type 1 (Business Wire)
Nov-09-21 07:00AM	AVROBIO to Present at Two Upcoming Investor Conferences in November (Business Wire)
Nov-08-21 07:00AM	AVROBIO to Present Clinical and Preclinical Data at the 14th ICIEM Conference (Business Wire)
Nov-05-21 07:00AM	AVROBIO Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) (Business Wire)

Tectonic Therapeutic, Inc. is a clinical-stage biotechnology company, which engages in the discovery and development of therapeutic proteins and antibodies that modulate the activity of G protein-coupled receptors (GPCR). It develops a proprietary technology platform called GEODe to enable the discovery and development of GPCR-targeted biologic medicines. The company was founded by Timothy A. Springer and Andrew Kruse in November 2015 and is headquartered in Watertown, MA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
SPRINGER TIMOTHY A	Director	Apr 11 '25	Buy	16.31	53,706	875,945	1,503,358	Apr 11 06:12 PM
SPRINGER TIMOTHY A	Director	Apr 10 '25	Buy	16.73	45,858	767,204	1,449,652	Apr 11 06:12 PM
SPRINGER TIMOTHY A	Director	Apr 09 '25	Buy	14.76	21,071	311,020	1,403,794	Apr 11 06:12 PM
SPRINGER TIMOTHY A	Director	Apr 11 '25	Buy	16.31	9,478	154,586	4,334,846	Apr 11 06:12 PM
SPRINGER TIMOTHY A	Director	Apr 10 '25	Buy	16.73	8,092	135,379	4,325,368	Apr 11 06:12 PM
SPRINGER TIMOTHY A	Director	Apr 09 '25	Buy	14.76	3,718	54,880	4,317,276	Apr 11 06:12 PM
SPRINGER TIMOTHY A	Director	Apr 07 '25	Buy	17.10	412,500	7,053,750	1,382,723	Apr 09 05:38 PM
SPRINGER TIMOTHY A	Director	Apr 07 '25	Buy	17.10	87,500	1,496,250	4,313,558	Apr 09 05:38 PM
MCGUIRE TERRANCE	Director	Apr 07 '25	Sale	17.10	500,000	8,550,000	573,062	Apr 07 05:02 PM
SPRINGER TIMOTHY A	Director	Feb 05 '25	Buy	50.00	660,000	33,000,000	970,223	Feb 07 04:21 PM
SPRINGER TIMOTHY A	Director	Feb 05 '25	Buy	54.14	129,294	6,999,977	4,226,058	Feb 07 04:21 PM
Lochner Daniel	Chief Financial Officer	Feb 05 '25	Buy	54.14	4,617	249,964	4,617	Feb 07 04:19 PM
Schwabish Marc	Chief Business Officer	Jan 28 '25	Option Exercise	2.38	2,700	6,426	4,700	Jan 29 04:05 PM
Schwabish Marc	Chief Business Officer	Dec 09 '24	Option Exercise	2.38	2,000	4,760	2,000	Dec 11 04:21 PM
McNamara Peter	Chief Scientific Officer	Dec 03 '24	Option Exercise	2.38	3,500	8,330	14,188	Dec 05 04:32 PM
SPRINGER TIMOTHY A	Director	Oct 22 '24	Buy	33.59	300,000	10,077,000	4,096,764	Oct 24 05:04 PM
SPRINGER TIMOTHY A	Director	Sep 26 '24	Buy	28.82	50,000	1,440,829	3,796,764	Sep 26 06:15 PM
Leonard Braden Michael	10% Owner	May 13 '24	Buy	1.25	469,753	585,546	4,471,380	May 15 11:21 AM
Leonard Braden Michael	10% Owner	May 14 '24	Buy	1.30	296,882	385,947	4,768,262	May 15 11:21 AM

Open in Screener

IVVD

Invivyd Inc

Apr 15 • 04:00PM ET

0.5140

Dollar change -0.0111
Percentage change -2.11	%

Healthcare • Biotechnology • USA • NASD

Peers: PFE MRNA BNTX MRK JNJ NVAX AZN GSK GILD SNY

| Held by: VTI IWM VXF VTWO IWN IWC VTWV PRFZ RSSL VTHR

Index	RUT	P/E	-	EPS (ttm)	-1.43	Insider Own	36.70%	Shs Outstand	119.84M	Perf Week	3.46%
Market Cap	61.66M	Forward P/E	0.60	EPS next Y	0.86	Insider Trans	-3.55%	Shs Float	75.94M	Perf Month	-32.74%
Income	-169.93M	PEG	-	EPS next Q	-0.03	Inst Own	52.17%	Short Float	10.88%	Perf Quarter	27.01%
Sales	25.38M	P/S	2.43	EPS this Y	107.93%	Inst Trans	-18.12%	Short Ratio	0.55	Perf Half Y	-49.61%
Book/sh	0.56	P/B	0.91	EPS next Y	661.77%	ROA	-94.75%	Short Interest	8.26M	Perf Year	-82.58%
Cash/sh	0.58	P/C	0.89	EPS next 5Y	-	ROE	-138.71%	52W Range	0.35 - 3.01	Perf YTD	16.00%
Dividend Est.	-	P/FCF	-	EPS past 5Y	-24.99%	ROI	-251.60%	52W High	-82.92%	Beta	0.47
Dividend TTM	-	Quick Ratio	1.62	Sales past 5Y	0.00%	Gross Margin	81.36%	52W Low	44.95%	ATR (14)	0.10
Dividend Ex-Date	-	Current Ratio	1.62	EPS Y/Y TTM	20.91%	Oper. Margin	-696.80%	RSI (14)	36.31	Volatility	12.56% 13.79%
Employees	99	Debt/Eq	0.02	Sales Y/Y TTM	-	Profit Margin	-669.42%	Recom	1.67	Target Price	6.60
Option/Short	Yes / Yes	LT Debt/Eq	0.00	EPS Q/Q	77.05%	Payout	-	Rel Volume	0.07	Prev Close	0.53
Sales Surprise	1.72%	EPS Surprise	25.00%	Sales Q/Q	-	Earnings	Mar 20 BMO	Avg Volume	15.04M	Price	0.51
SMA20	-13.05%	SMA50	-48.45%	SMA200	-42.85%	Trades		Volume	1,057,278	Change	-2.11%

Date	Action	Analyst	Rating Change	Price Target Change
Apr-05-24	Upgrade	Guggenheim	Neutral → Buy	$9
Mar-26-24	Upgrade	Morgan Stanley	Equal-Weight → Overweight	$4 → $10
Dec-19-23	Upgrade	Morgan Stanley	Underweight → Equal-Weight	$1 → $4
May-01-23	Initiated	H.C. Wainwright	Buy	$5

Mar-26-25 04:15PM	Invivyd Appoints Ajay Royan, Founder of Mithril Capital, to its Board of Directors (GlobeNewswire) -6.70%
Mar-20-25 09:25AM	Invivyd, Inc. (IVVD) Reports Q4 Loss, Tops Revenue Estimates (Zacks)
08:01AM	Invivyd Reports Fourth Quarter and Full-Year 2024 Financial Results and Provides Recent Business Highlights (GlobeNewswire)
Mar-12-25 09:40AM	Are Investors Undervaluing Invivyd, Inc. (IVVD) Right Now? (Zacks)
Mar-05-25 07:05AM	Invivyd Announces Continued Neutralizing Activity of PEMGARDA (pemivibart) Against Currently Dominant SARS-CoV-2 Variant LP.8.1 (GlobeNewswire)
11:32AM	Loading…
Mar-02-25 11:32AM	Why Invivyd, Inc. (IVVD) is Skyrocketing So Far in 2025 (Insider Monkey)
Feb-28-25 12:12PM	Adagio Medical cuts workforce and pauses cryo catheter launch in EU (Medical Device Network) -6.45%
Feb-24-25 07:05AM	FDA Declined Invivyd's Request to Expand Existing Emergency Use Authorization of PEMGARDA (pemivibart) to Include Treatment of Mild-to-Moderate COVID-19 For Immunocompromised Persons Who Have No Alternative Therapeutic Options; No Change to the Existing PEMGARDA EUA for Pre-Exposure Prophylaxis of COVID-19 in Certain Immunocompromised Patients (GlobeNewswire) -29.94%
Feb-18-25 10:27AM	Why Invivyd, Inc. (IVVD) Is Soaring This Year So Far (Insider Monkey) -9.32%
Feb-10-25 07:00AM	Invivyd to Present at the Oppenheimer 35th Annual Healthcare Life Sciences Conference on February 12, 2025 (GlobeNewswire) -23.04%
Feb-05-25 09:30AM	Invivyd Announces Partnership with Pro Football Coach Jim Harbaugh to Elevate Awareness and Ongoing Impact of COVID-19: Common, Not A Cold (GlobeNewswire) +68.80%
Feb-03-25 07:20PM	Why Invivyd Inc (IVVD) Is Skyrocketing So Far In 2025 (Insider Monkey) +196.34% +17.92%
07:00AM	Invivyd Announces Positive Phase 1/2 Clinical Data for VYD2311, a Monoclonal Antibody Designed to be a Superior Alternative to COVID-19 Vaccination for the Broad Population (GlobeNewswire)
06:55AM	Invivyd Announces Preliminary Fourth Quarter 2024 Financial Results, Strong Revenue Growth, and Reiterates Goal of Near-Term Profitability (GlobeNewswire)
Jan-27-25 07:01AM	Invivyd Provides Another Positive SARS-CoV-2 Variant Data Analysis to Satisfy U.S. FDA's Gating Request for Completing Its Review of EUA Request for PEMGARDA (pemivibart) for the Treatment of Mild-to-Moderate COVID-19 in Certain Immunocompromised Patients (GlobeNewswire) -12.85%
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Jan-10-25 12:12PM	What's Going On With COVID-19 Antibody Developer Invivyd Stock On Friday? (Benzinga)
07:01AM	Invivyd Announces Continued Neutralizing Activity of PEMGARDA (pemivibart) Against Dominant SARS-CoV-2 Variant XEC (GlobeNewswire)
Jan-07-25 09:34AM	Why Invivyd, Inc. (IVVD) Is Among the Best Penny Stocks to Invest In According to Media? (Insider Monkey)
Dec-17-24 06:25AM	Adagio Medical announces Todd Usen as new CEO and director (Medical Device Network) +8.77%
Nov-15-24 03:17AM	Q3 2024 Invivyd Inc Earnings Call (Thomson Reuters StreetEvents)
02:11AM	Invivyd Inc (IVVD) Q3 2024 Earnings Call Highlights: Strong Revenue and Strategic Growth Amidst ... (GuruFocus.com)
Nov-14-24 08:20AM	Invivyd, Inc. (IVVD) Reports Q3 Loss, Misses Revenue Estimates (Zacks) -11.18%
07:05AM	Invivyd Reports Third Quarter 2024 Financial Results and Recent Business Highlights (GlobeNewswire)
07:01AM	Invivyd Announces New England Journal of Medicine Publishes Letter to the Editor Highlighting Immunobridging Pathway Leading to PEMGARDA (pemivibart) Emergency Use Authorization; Comments on Adjacent Third-Party Letter to the Editor (GlobeNewswire)
Nov-13-24 07:27AM	Invivyd Inc (IVVD) Q3 2024 Earnings Report Preview: What to Expect (GuruFocus.com) -11.00%
Nov-12-24 08:30AM	Invivyd Announces Preprints Conveying CANOPY Phase 3 Clinical Trial Data Including Long-Term Protection Versus Recent JN.1 Sublineages at Low Residual Titers, and Describing a Novel Approach for Predicting Monoclonal Antibody Activity Were Uploaded to MedRxiv and BioRxiv, Respectively (GlobeNewswire)
Nov-06-24 08:01AM	Invivyd to Participate in the Guggenheim Securities Healthcare Innovation Conference (GlobeNewswire) +12.62%
07:01AM	Invivyd to Host Third Quarter 2024 Financial Results and Corporate Update Conference Call on November 14, 2024 (GlobeNewswire)
Oct-29-24 07:03AM	Invivyd Reports Preliminary Third Quarter 2024 Results, Withdraws Prior Financial Guidance, and Targets Near-Term Profitability (GlobeNewswire) -12.80%
07:01AM	Invivyd Phase 3 Long-Term Exploratory Clinical Efficacy Data Shows PEMGARDA (pemivibart) Provided Substantial Protection from Symptomatic COVID-19 Versus Placebo Over Six Months of Follow-Up, With No Additional Doses, In Immunocompetent Participants (GlobeNewswire)
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Oct-16-24 07:01AM	Invivyd to Present PEMGARDA (pemivibart) Data at Infectious Disease Week (IDWeek) 2024 (GlobeNewswire)
Oct-01-24 07:01AM	Invivyd Announces U.S. FDA Has Updated the PEMGARDA EUA Fact Sheet with Accurate SARS-CoV-2 Variant Susceptibility and PEMGARDA Activity Data (GlobeNewswire) -11.75%
Sep-23-24 07:01AM	Invivyd Provides Detailed Virology Data and Analysis of SARS-CoV-2 Structural Biology Predicting Anticipated Neutralization Activity for PEMGARDA (pemivibart) (GlobeNewswire)
Sep-12-24 07:01AM	Invivyd at the Ready for Upcoming Respiratory Virus Season with PEMGARDA (pemivibart) to Help Protect Vulnerable Immunocompromised Persons from COVID-19 (GlobeNewswire) +12.75%
Sep-05-24 07:01AM	Invivyd to Participate in Upcoming Investor Conferences (GlobeNewswire)
Sep-04-24 07:01AM	Invivyd Doses First Participants in Phase 1 Clinical Trial of VYD2311, a Next Generation Monoclonal Antibody Candidate for COVID-19, Building on the Success of PEMGARDA (GlobeNewswire)
Sep-03-24 07:01AM	Invivyd Announces Continued Neutralizing Activity of PEMGARDA (pemivibart) Against Dominant SARS-CoV-2 Variants KP.3.1.1 and LB.1, and Other Variants of Interest (GlobeNewswire)
Aug-27-24 07:01AM	Invivyd Announces PEMGARDA (pemivibart) Demonstrated 84% Relative Risk Reduction in Symptomatic COVID-19 Compared to Placebo in an Exploratory Analysis from Ongoing CANOPY Phase 3 Clinical Trial (GlobeNewswire) -28.67%
Aug-15-24 02:43AM	Q2 2024 Invivyd Inc Earnings Call (Thomson Reuters StreetEvents) +6.12%
Aug-14-24 09:10AM	Invivyd, Inc. (IVVD) Reports Q2 Loss, Lags Revenue Estimates (Zacks) -7.55%
08:01AM	Invivyd Reports Second Quarter 2024 Financial Results and Recent Business Highlights (GlobeNewswire)
Aug-12-24 04:01PM	Invivyd to Host Conference Call Discussing Second Quarter 2024 Financial Results and Business Highlights (GlobeNewswire) -6.31% +9.84%
Jul-01-24 07:01AM	Invivyd Announces its Addition to the Russell 2000 and Russell 3000 Indexes (GlobeNewswire) +9.09%
Jun-14-24 07:01AM	Invivyd Announces Antiviral Activity of VYD222 (pemivibart) Against SARS-CoV-2 KP.1.1 FLiRT & KP.3 Variants (GlobeNewswire) -7.06%
Jun-03-24 04:01PM	Invivyd to Participate at the Jefferies Global Healthcare Conference (GlobeNewswire)
May-31-24 07:05AM	Invivyd Announces General Alignment with U.S. FDA on a Repeatable, Expedient Emergency Use Authorization Pathway for the Prevention and Treatment of Symptomatic COVID-19, Based on Compact Clinical Programs to Establish Safety and Immunobridging for Serial Monoclonal Antibodies (GlobeNewswire)
07:00AM	Invivyd Announces the Appointment of Timothy Lee as Chief Commercial Officer (GlobeNewswire)
May-29-24 07:00AM	Invivyd to Present Data at 2024 American Society of Clinical Oncology (ASCO) Annual Meeting and 2024 American Transplant Congress (ATC) (GlobeNewswire)
May-22-24 07:00AM	Invivyd Elects Two New Independent Members to its Board of Directors (GlobeNewswire)
May-13-24 04:01PM	Invivyd to Participate at the H.C. Wainwright 2nd Annual BioConnect Investor Conference (GlobeNewswire)
10:44AM	Invivyd, Inc. (NASDAQ:IVVD) Q1 2024 Earnings Call Transcript (Insider Monkey)
May-10-24 03:25PM	Invivyd Inc (IVVD) Reports Q1 2024 Financial Results: A Detailed Analysis (GuruFocus.com) -6.61%
May-09-24 10:56PM	IVVD Stock Earnings: Invivyd Meets EPS for Q1 2024 (InvestorPlace)
04:01PM	Invivyd Reports First Quarter 2024 Financial Results and Recent Business Highlights (GlobeNewswire)
May-07-24 07:30AM	Invivyd to Pursue Rapid Immunobridging Pathway to Potential EUA for Treatment of COVID-19 in Moderately to Severely Immunocompromised People, Based on U.S. FDA Feedback (GlobeNewswire) +6.36%
May-02-24 05:13PM	Invivyd to Host Conference Call Discussing First Quarter 2024 Financial Results and Business Highlights (GlobeNewswire)
Apr-30-24 07:30AM	Invivyd Announces $20 Million to $25 Million Improvement in Projected 2024 Year-End Cash Position (GlobeNewswire) +6.73%
Apr-15-24 07:30AM	Invivyd Receives Healthcare Common Procedure Coding System (HCPCS) Reimbursement Codes from the U.S. Centers for Medicare & Medicaid Services (CMS) Covering PEMGARDA (GlobeNewswire)
Apr-12-24 07:30AM	Invivyd Announces CEO Transition (GlobeNewswire)
Apr-04-24 04:01PM	Invivyd Provides PEMGARDA Launch Update and Announces 2024 Net Product Revenue Guidance in the Range of $150 Million to $200 Million (GlobeNewswire) -8.91% -7.82%
Mar-28-24 01:53PM	IVVD Stock Earnings: Invivyd Misses EPS for Q4 2023 (InvestorPlace) +11.00%
07:00AM	Invivyd Reports Full Year 2023 Financial Results and Recent Business Highlights (GlobeNewswire)
Mar-22-24 03:28PM	Invivyd Announces Interim Exploratory Data on VYD222 from Ongoing CANOPY Clinical Trial (GlobeNewswire) +41.10%
03:04PM	Invivyd Announces FDA Authorization for Emergency Use of PEMGARDA (Formerly VYD222) for Pre-exposure Prophylaxis (PrEP) of COVID-19 (GlobeNewswire)
Feb-05-24 04:02PM	Invivyd to Participate at the Guggenheim Healthcare Talks 6th Annual Biotechnology Conference (GlobeNewswire)
Jan-29-24 12:35PM	3 Groundbreaking Biotech Stocks to Invest in Now (InvestorPlace) +11.31%
Jan-12-24 12:00PM	All You Need to Know About Invivyd, Inc. (IVVD) Rating Upgrade to Strong Buy (Zacks)
Jan-03-24 07:00AM	Invivyd Submits Request for Emergency Use Authorization (EUA) to U.S. FDA for VYD222 for the Pre-exposure Prevention of COVID-19 in Immunocompromised Adults and Adolescents (GlobeNewswire)
Dec-23-23 05:29AM	Invivyd Stock More Than Doubled Last Week. Is It Too Late to Buy? (Motley Fool)
Dec-19-23 11:52AM	Invivyd (IVVD) Surges on Positive Data From COVID-19 Study (Zacks) -7.52%
Dec-18-23 07:00AM	Invivyd Announces Positive Initial Results from Ongoing CANOPY Phase 3 Pivotal Clinical Trial Investigating VYD222 for the Prevention of COVID-19 (GlobeNewswire) +120.25%
Nov-13-23 10:21AM	Invivyd, Inc. (NASDAQ:IVVD) Q3 2023 Earnings Call Transcript (Insider Monkey) +7.14%
Nov-10-23 08:35AM	Q3 2023 Invivyd Inc Earnings Call (Thomson Reuters StreetEvents)
Nov-09-23 04:01PM	Invivyd Reports Third Quarter 2023 Financial Results and Recent Business Highlights (GlobeNewswire) -7.89%
Nov-02-23 04:01PM	Invivyd to Host Conference Call Discussing Third Quarter 2023 Financial Results and Business Highlights (GlobeNewswire) +5.44%
Oct-31-23 04:01PM	Invivyd to Participate in Upcoming Investor Conferences (GlobeNewswire) -6.96%
Sep-11-23 07:00AM	Invivyd Announces Dosing of First Participant in CANOPY Phase 3 Pivotal Clinical Trial Investigating VYD222 for the Prevention of Symptomatic COVID-19 (GlobeNewswire)
Sep-06-23 08:17PM	7 Biotech Stocks to Sell in September Before They Crash & Burn (InvestorPlace)
07:00AM	Invivyd to Participate in Upcoming Investor Conferences (GlobeNewswire)
Sep-05-23 07:00AM	Invivyd Appoints William Duke as Chief Financial Officer (GlobeNewswire)
Aug-29-23 01:13PM	Invivyd (IVVD) Stock Rises 18% in 3 Months: Here's Why (Zacks)
Aug-15-23 05:45AM	Invivyd, Inc. (NASDAQ:IVVD) Q2 2023 Earnings Call Transcript (Insider Monkey)
Aug-11-23 06:43AM	Q2 2023 Invivyd Inc Earnings Call (Thomson Reuters StreetEvents)
Aug-10-23 04:01PM	Invivyd Reports Second Quarter 2023 Financial Results and Business Highlights (GlobeNewswire)
Aug-03-23 04:01PM	Invivyd to Host Conference Call Discussing Second Quarter 2023 Financial Results and Business Highlights (GlobeNewswire)
Jul-27-23 04:01PM	Invivyd Announces Appointment of Sara Cotter to Board Of Directors (GlobeNewswire)
Jul-17-23 02:15PM	Invivyd's COVID-19 Antibody Shows Favorable Safety, Tolerability Profile For Immunocompromised People (Benzinga)
07:00AM	Invivyd Announces Additional Positive Initial Data from Ongoing Phase 1 Clinical Trial of VYD222, a Monoclonal Antibody Candidate in Development for the Prevention of Symptomatic COVID-19 in Immunocompromised People (GlobeNewswire)
Jun-26-23 07:00AM	Invivyd Announces General Alignment with FDA on Pathway to Potential EUA for VYD222 and Anticipated Follow-On Monoclonal Antibody Candidates Designed to Prevent COVID-19 (GlobeNewswire)
Jun-22-23 01:07PM	Invivyd Says Investigational Antibody Shows Potential To Prevent Symptomatic COVID-19 (Benzinga) -6.19%
07:00AM	Invivyd Announces Positive Initial Data from Ongoing Phase 1 Clinical Trial of VYD222, a Monoclonal Antibody Candidate in Development for the Prevention of Symptomatic COVID-19 in Immunocompromised People (GlobeNewswire)
Jun-01-23 07:00AM	Invivyd to Participate at the Jefferies Healthcare Conference (GlobeNewswire) -16.67%
May-23-23 06:25AM	Is Invivyd (NASDAQ:IVVD) In A Good Position To Deliver On Growth Plans? (Simply Wall St.) +19.72%
May-11-23 04:01PM	Invivyd Reports First Quarter 2023 Financial Results and Business Highlights (GlobeNewswire)
May-04-23 04:01PM	Invivyd to Host Conference Call Discussing First Quarter 2023 Financial Results and Business Highlights (GlobeNewswire)
Apr-25-23 04:01PM	Invivyd to Participate at H.C. Wainwrights BioConnect Investor Conference (GlobeNewswire)
07:00AM	Invivyd Announces the FDA Has Cleared Its IND Application for VYD222, a Monoclonal Antibody Candidate for Prevention of COVID-19, and Provides Phase 1 VYD222 Clinical Trial Update (GlobeNewswire)
Apr-14-23 09:35AM	After Plunging -26.71% in 4 Weeks, Here's Why the Trend Might Reverse for Invivyd, Inc. (IVVD) (Zacks)
Apr-12-23 07:00AM	Invivyd Appoints Robert Allen as Chief Scientific Officer and Stacy Price as Chief Technology and Manufacturing Officer (GlobeNewswire)
Mar-30-23 04:01PM	Invivyd Doses First Participants in Phase 1 Trial of VYD222, a Novel Monoclonal Antibody Candidate for COVID-19 (GlobeNewswire) -8.14%

Invivyd, Inc. engages in the discovery, development and commercialization of antibody-based solutions for infectious diseases with pandemic potential. The firm develops antibodies that can neutralize SARS-CoV-2, SARS-CoV-1, and additional emergent coronaviruses. It offers, ADG20, a monoclonal antibody targeting the spike protein of SARS-CoV-2 and related coronaviruses. The company was founded by Tillman U. Gerngross, Ren Russo and Laura Walker on June 3, 2020 and is headquartered in Waltham, MA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
MCGUIRE TERRANCE	Director	Dec 31 '24	Sale	0.45	103,474	46,098	3,066,757	Dec 31 07:16 PM
MCGUIRE TERRANCE	Director	Dec 27 '24	Sale	0.52	83,744	43,647	3,256,776	Dec 31 07:16 PM
MCGUIRE TERRANCE	Director	Dec 30 '24	Sale	0.48	86,545	41,784	3,170,231	Dec 31 07:16 PM
MCGUIRE TERRANCE	Director	Dec 20 '24	Sale	0.42	119,805	50,725	3,568,274	Dec 26 07:46 PM
MCGUIRE TERRANCE	Director	Dec 26 '24	Sale	0.54	83,817	45,563	3,340,520	Dec 26 07:46 PM
MCGUIRE TERRANCE	Director	Dec 24 '24	Sale	0.51	68,161	34,503	3,424,337	Dec 26 07:46 PM
MCGUIRE TERRANCE	Director	Dec 23 '24	Sale	0.45	75,776	34,076	3,492,498	Dec 26 07:46 PM
POLARIS PARTNERS IX, LP	Director	Dec 20 '24	Proposed Sale	0.44	1,000,000	443,900		Dec 20 04:46 PM
MCGUIRE TERRANCE	Director	Dec 19 '24	Sale	0.43	152,067	65,951	3,688,079	Dec 19 05:54 PM
MCGUIRE TERRANCE	Director	Dec 17 '24	Sale	0.48	97,410	46,757	3,914,910	Dec 19 05:54 PM
MCGUIRE TERRANCE	Director	Dec 18 '24	Sale	0.47	74,764	35,087	3,840,146	Dec 19 05:54 PM
MCGUIRE TERRANCE	Director	Dec 12 '24	Sale	0.58	125,000	72,875	4,077,679	Dec 16 08:29 PM
MCGUIRE TERRANCE	Director	Dec 16 '24	Sale	0.47	65,359	30,510	4,012,320	Dec 16 08:29 PM
MCGUIRE TERRANCE	Director	Dec 10 '24	Sale	0.59	175,000	103,005	4,363,079	Dec 11 06:26 PM
MCGUIRE TERRANCE	Director	Dec 11 '24	Sale	0.59	160,400	94,812	4,202,679	Dec 11 06:26 PM
MCGUIRE TERRANCE	Director	Dec 09 '24	Sale	0.61	150,000	91,560	4,538,079	Dec 11 06:26 PM
POLARIS PARTNERS IX, LP	Director	Dec 09 '24	Proposed Sale	0.61	1,000,000	610,400		Dec 09 04:27 PM
MCGUIRE TERRANCE	Director	May 29 '24	Sale	1.66	112,381	186,575	4,688,079	May 31 05:09 PM

Open in Screener

ALEC

Alector Inc

Apr 15 • 04:00PM ET

1.08

Dollar change +0.10
Percentage change 10.11	%

Healthcare • Biotechnology • USA • NASD

Peers: BIIB REGN IONS VRTX SGMO SAGE ACAD LLY GILD AVXL

| Held by: VTI IWM VXF IWO VTWO IBB SCHA VHT IWC VTWG

Index	RUT	P/E	-	EPS (ttm)	-1.24	Insider Own	24.37%	Shs Outstand	99.09M	Perf Week	14.61%
Market Cap	107.01M	Forward P/E	-	EPS next Y	-1.61	Insider Trans	-0.88%	Shs Float	74.94M	Perf Month	-21.74%
Income	-119.05M	PEG	-	EPS next Q	-0.48	Inst Own	68.30%	Short Float	7.26%	Perf Quarter	-33.94%
Sales	100.56M	P/S	1.06	EPS this Y	-63.83%	Inst Trans	1.68%	Short Ratio	8.46	Perf Half Y	-77.50%
Book/sh	1.28	P/B	0.84	EPS next Y	20.06%	ROA	-21.84%	Short Interest	5.44M	Perf Year	-82.06%
Cash/sh	4.17	P/C	0.26	EPS next 5Y	4.34%	ROE	-91.24%	52W Range	0.87 - 6.78	Perf YTD	-42.86%
Dividend Est.	-	P/FCF	-	EPS past 5Y	6.31%	ROI	-74.14%	52W High	-84.07%	Beta	0.78
Dividend TTM	-	Quick Ratio	3.40	Sales past 5Y	164.35%	Gross Margin	91.21%	52W Low	24.14%	ATR (14)	0.11
Dividend Ex-Date	-	Current Ratio	3.40	EPS Y/Y TTM	20.41%	Oper. Margin	-142.00%	RSI (14)	41.29	Volatility	10.82% 8.74%
Employees	238	Debt/Eq	0.34	Sales Y/Y TTM	3.60%	Profit Margin	-118.39%	Recom	2.12	Target Price	4.26
Option/Short	Yes / Yes	LT Debt/Eq	0.27	EPS Q/Q	95.70%	Payout	-	Rel Volume	1.65	Prev Close	0.98
Sales Surprise	174.24%	EPS Surprise	96.79%	Sales Q/Q	257.08%	Earnings	Feb 26 AMC	Avg Volume	643.41K	Price	1.08
SMA20	-6.44%	SMA50	-24.61%	SMA200	-69.04%	Trades		Volume	1,060,403	Change	10.11%

Date	Action	Analyst	Rating Change	Price Target Change
Dec-17-24	Downgrade	Mizuho	Outperform → Neutral	$9 → $2.50
Dec-16-24	Downgrade	Stifel	Buy → Hold	$4
Dec-04-24	Downgrade	BofA Securities	Neutral → Underperform	$9 → $1
Nov-29-24	Reiterated	H.C. Wainwright	Buy	$35 → $7
Nov-26-24	Downgrade	Morgan Stanley	Equal-Weight → Underweight	$10 → $3
Dec-14-23	Upgrade	Stifel	Hold → Buy	$8 → $15
Dec-12-23	Initiated	Deutsche Bank	Buy	$12
Sep-25-23	Initiated	Goldman	Sell	$4
Sep-22-23	Initiated	Cantor Fitzgerald	Overweight	$13
Jan-06-23	Downgrade	BofA Securities	Buy → Neutral	$24 → $12
Sep-09-22	Downgrade	Morgan Stanley	Overweight → Equal-Weight	$27 → $13
Jul-07-22	Initiated	Mizuho	Buy	$15
Apr-13-22	Initiated	Goldman	Sell	$9
Mar-08-22	Downgrade	Stifel	Buy → Hold	$32 → $18
Sep-27-21	Initiated	William Blair	Outperform
Jan-15-21	Resumed	BofA Securities	Buy	$35
Jun-24-20	Initiated	H.C. Wainwright	Buy	$41
Apr-28-20	Initiated	Goldman	Buy	$32
Mar-06-20	Initiated	Citigroup	Buy	$40
Feb-27-20	Initiated	Barclays	Overweight	$36

Show Previous Ratings

Mar-28-25 04:05PM	Alector Provides Executive Leadership Update (GlobeNewswire)
Feb-27-25 12:32PM	Q4 2024 Alector Inc Earnings Call (Thomson Reuters StreetEvents)
02:24AM	Alector Inc (ALEC) Q4 2024 Earnings Call Highlights: Strong Cash Position and Promising ... (GuruFocus.com)
Feb-26-25 05:55PM	Alector (ALEC) Reports Q4 Loss, Tops Revenue Estimates (Zacks)
04:53PM	Alector: Q4 Earnings Snapshot (Associated Press Finance)
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04:05PM	Alector Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Business Update (GlobeNewswire)
Feb-25-25 11:01AM	Alector Inc (ALEC) Q4 2024 Earnings Report Preview: What to Expect (GuruFocus.com)
08:00AM	Alector to Participate in Upcoming Healthcare Conferences (GlobeNewswire)
Feb-19-25 04:05PM	Alector to Host Fourth Quarter and Full-Year 2024 Earnings Conference Call (GlobeNewswire)
Jan-13-25 08:00AM	Alector Reports on Recent Progress and Outlines Strategic Priorities for 2025 (GlobeNewswire)
Nov-27-24 06:50AM	Alector price target lowered to $7 from $35 at H.C. Wainwright (TipRanks)
Nov-26-24 09:00AM	Alector stock drops after Alzheimers drug fails in Phase II trial (Clinical Trials Arena) -35.10%
03:44AM	Alector turns to layoffs as Alzheimers drug fails (BioPharma Dive)
Nov-25-24 04:05PM	Alector Announces Results from AL002 INVOKE-2 Phase 2 Trial in Individuals with Early Alzheimer's Disease and Provides Business Update (GlobeNewswire)
Nov-14-24 04:05PM	Alector Secures Flexible Credit Facility for Up to $50 Million From Hercules Capital (GlobeNewswire) -17.21%
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Nov-06-24 05:50PM	Alector (ALEC) Reports Q3 Loss, Misses Revenue Estimates (Zacks) +7.63%
04:43PM	Alector: Q3 Earnings Snapshot (Associated Press Finance)
04:05PM	Alector Reports Third Quarter 2024 Financial Results and Provides Business Update (GlobeNewswire)
Sep-19-24 08:00AM	Alector Presents Baseline Characteristics for Pivotal INFRONT-3 Phase 3 Clinical Trial at the 14th International Conference on Frontotemporal Dementias (ISFTD 2024) (GlobeNewswire) +8.87%
Aug-29-24 07:00AM	Alector to Participate in Upcoming Healthcare Conferences (GlobeNewswire)
Aug-23-24 07:19PM	Director Richard Scheller Sells 44,250 Shares of Alector Inc (ALEC) (GuruFocus.com)
Aug-07-24 06:15PM	Alector (ALEC) Reports Q2 Loss, Lags Revenue Estimates (Zacks)
05:11PM	Alector: Q2 Earnings Snapshot (Associated Press Finance)
04:05PM	Alector Reports Second Quarter 2024 Financial Results and Provides Business Update (GlobeNewswire)
Jul-31-24 04:05PM	Alector to Host Mid-Year Earnings Conference Call (GlobeNewswire)
Jul-28-24 08:05AM	Alector Presents Baseline Characteristics for INVOKE-2 Phase 2 Clinical Trial of AL002 at the Alzheimer's Association International Conference 2024 (AAIC ) (GlobeNewswire)
Jul-23-24 07:00AM	Alector to Present Data on Pipeline Focus Areas at the Alzheimer's Association International Conference (AAIC ) 2024 (GlobeNewswire)
Jun-29-24 08:43PM	Why Did Analysts Give Alector, Inc. (ALEC) a Moderate Buy Rating? (Insider Monkey)
06:30PM	10 Best Biotech Penny Stocks to Buy Now (Insider Monkey)
Jun-20-24 07:00AM	Alector to Participate in the H.C. Wainwright 5th Annual Neuro Perspectives Virtual Conference (GlobeNewswire)
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Jun-10-24 07:00AM	Alector to Host Virtual Research and Development Event Highlighting Alector Brain Carrier Blood-Brain Barrier Technology Platform (GlobeNewswire)
Jun-03-24 07:00AM	Alector to Participate in the Goldman Sachs 45th Annual Global Healthcare Conference (GlobeNewswire)
May-09-24 07:00AM	Alector to Participate in Upcoming Healthcare Conferences (GlobeNewswire)
May-08-24 11:55PM	ALEC Stock Earnings: Alector Beats EPS, Beats Revenue for Q1 2024 (InvestorPlace)
06:25PM	Alector (ALEC) Reports Q1 Loss, Tops Revenue Estimates (Zacks)
05:19PM	Alector: Q1 Earnings Snapshot (Associated Press Finance)
04:05PM	Alector Reports First Quarter 2024 Financial Results and Provides Business Update (GlobeNewswire)
Apr-25-24 10:02AM	Will Alector (ALEC) Report Negative Q1 Earnings? What You Should Know (Zacks) -8.38%
Feb-28-24 02:02PM	Q4 2023 Alector Inc Earnings Call (Thomson Reuters StreetEvents)
10:13AM	Alector, Inc. (NASDAQ:ALEC) Q4 2023 Earnings Call Transcript (Insider Monkey)
07:00AM	Alector to Participate in Upcoming Healthcare Conferences (GlobeNewswire)
Feb-27-24 04:46PM	Alector Inc (ALEC) Reports Fourth Quarter and Full Year 2023 Financial Results (GuruFocus.com) +8.18%
04:23PM	Alector: Q4 Earnings Snapshot (Associated Press Finance)
04:05PM	Alector Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Business Update (GlobeNewswire)
Feb-20-24 04:05PM	Alector to Host Fourth Quarter and Full-Year 2023 Earnings Call (GlobeNewswire)
10:00AM	Earnings Preview: Alector (ALEC) Q4 Earnings Expected to Decline (Zacks)
Feb-08-24 07:00AM	Alector Announces First Patient Dosed in PROGRESS-AD Phase 2 Clinical Trial of AL101/GSK4527226 in Patients with Early Alzheimer's Disease (GlobeNewswire)
06:48AM	Strength Seen in Alector (ALEC): Can Its 6.0% Jump Turn into More Strength? (Zacks)
Feb-07-24 07:00AM	FDA Grants Latozinemab Breakthrough Therapy Designation for Frontotemporal Dementia Due to a Progranulin Gene Mutation (FTD-GRN) (GlobeNewswire) +5.96%
Jan-25-24 12:00PM	Alector (ALEC) Upgraded to Strong Buy: Here's What You Should Know (Zacks)
Jan-23-24 07:32AM	Brain Disease Cures: 3 Neuroscience Stocks Targeting Revolutionary Breakthroughs (InvestorPlace)
Jan-19-24 09:20AM	Alector Announces Closing of Public Offering (GlobeNewswire)
Jan-17-24 08:54AM	Alector Announces Pricing of Public Offering of Common Stock (GlobeNewswire) -14.01%
Jan-16-24 04:01PM	Alector Announces Proposed Public Offering of Common Stock (GlobeNewswire)
Jan-08-24 01:25PM	Eli Lilly, Crispr, Biogen Lead Pharma And Biotech Stocks To Great Expectations In 2024 (Investor's Business Daily) +7.34%
Dec-05-23 09:55AM	Wall Street Analysts Think Alector (ALEC) Could Surge 142.53%: Read This Before Placing a Bet (Zacks)
Nov-28-23 07:00AM	Alector to Host Two Virtual Research and Development Events Highlighting TREM2 and Progranulin Programs (GlobeNewswire)
Nov-14-23 09:35AM	Alector (ALEC) Loses -38.1% in 4 Weeks, Here's Why a Trend Reversal May be Around the Corner (Zacks) +14.06%
Nov-08-23 07:00AM	Alector to Participate in the Stifel Healthcare Conference (GlobeNewswire) -7.30%
Nov-07-23 06:02PM	Alector: Q3 Earnings Snapshot (Associated Press Finance) +5.12%
05:11PM	Alector Inc (ALEC) Reports Q3 2023 Financial Results with Key Clinical Advancements (GuruFocus.com)
04:05PM	Alector Reports Third Quarter 2023 Financial Results and Provides Business Update (GlobeNewswire)
Oct-27-23 07:00AM	Alector Announces Achievement of Target Enrollment in the Pivotal INFRONT-3 Phase 3 Clinical Trial of Latozinemab in Individuals with Frontotemporal Dementia Due to a Progranulin Gene Mutation (FTD-GRN) (GlobeNewswire)
Sep-14-23 01:12AM	10% Owner Polaris Venture Management Co. VI, L.L.C. Sells 500,000 Shares of Alector Inc (GuruFocus.com)
Sep-08-23 12:10PM	Alector (ALEC) Up 7% on Finishing Enrolment in Alzheimer Study (Zacks)
Sep-07-23 07:00AM	Alector Announces Completion of Enrollment in the INVOKE-2 Phase 2 Clinical Trial of AL002, a TREM2 Monoclonal Antibody, in Individuals With Early Alzheimers Disease (GlobeNewswire) +6.76%
Aug-31-23 07:00AM	Alector to Participate in Upcoming Healthcare Conferences (GlobeNewswire)
Aug-10-23 09:55AM	Wall Street Analysts Believe Alector (ALEC) Could Rally 102%: Here's is How to Trade (Zacks)
Aug-03-23 05:45PM	Alector (ALEC) Surpasses Q2 Earnings and Revenue Estimates (Zacks) +32.38%
04:43PM	Alector: Q2 Earnings Snapshot (Associated Press Finance)
04:05PM	Alector Reports Second Quarter 2023 Financial Results and Provides Business Update (GlobeNewswire)
Jul-27-23 08:30AM	Alector to Host Mid-Year Earnings Conference Call (GlobeNewswire)
Jul-13-23 01:29PM	7 Stocks That AI Says Will Make You a Millionaire by 2025 (InvestorPlace)
Jun-06-23 07:00AM	Alector to Participate in the Goldman Sachs 44th Annual Global Healthcare Conference (GlobeNewswire)
Jun-01-23 07:29AM	Companies Like Alector (NASDAQ:ALEC) Are In A Position To Invest In Growth (Simply Wall St.) -8.20%
May-09-23 09:55AM	Does Alector (ALEC) Have the Potential to Rally 86.38% as Wall Street Analysts Expect? (Zacks)
May-05-23 06:31AM	Benign Growth For Alector, Inc. (NASDAQ:ALEC) Underpins Its Share Price (Simply Wall St.) +10.27%
May-04-23 07:35PM	Alector (ALEC) Reports Q1 Loss, Tops Revenue Estimates (Zacks)
06:27PM	Alector: Q1 Earnings Snapshot (AP Finance)
04:05PM	Alector Reports First Quarter 2023 Financial Results and Provides Business Update (GlobeNewswire)
May-02-23 07:00AM	Alector to Participate in the BofA Securities 2023 Healthcare Conference (GlobeNewswire)
May-01-23 10:01AM	Acadia Pharmaceuticals (ACAD) Expected to Beat Earnings Estimates: Should You Buy? (Zacks)
Apr-27-23 10:03AM	Analysts Estimate Alector (ALEC) to Report a Decline in Earnings: What to Look Out for (Zacks)
Apr-13-23 12:59PM	Shareholders in Alector (NASDAQ:ALEC) are in the red if they invested three years ago (Simply Wall St.)
08:30AM	Are Options Traders Betting on a Big Move in Alector (ALEC) Stock? (Zacks)
Mar-01-23 04:05PM	Alector to Participate in Upcoming Healthcare Conferences (GlobeNewswire) -6.36%
Feb-28-23 04:05PM	Alector Reports Fourth Quarter and Full Year 2022 Financial Results and Provides Corporate Update (GlobeNewswire)
Feb-20-23 10:00AM	Merus N.V. (MRUS) Expected to Beat Earnings Estimates: Should You Buy? (Zacks)
Feb-17-23 06:01AM	Alector, Inc. (NASDAQ:ALEC) is a favorite amongst institutional investors who own 64% (Simply Wall St.)
Feb-16-23 10:01AM	Alector (ALEC) Expected to Beat Earnings Estimates: Should You Buy? (Zacks)
Dec-21-22 05:01AM	We're Not Very Worried About Alector's (NASDAQ:ALEC) Cash Burn Rate (Simply Wall St.)
Dec-08-22 04:30PM	Alector Reports Inducement Grants under Nasdaq Listing Rule 5635(c)(4) (GlobeNewswire)
Nov-29-22 11:05AM	Alector Presents Results from First-in-Human Phase 1 Study of AL101 for the Treatment of Neurodegenerative Diseases (GlobeNewswire)
Nov-10-22 05:13AM	Alector Third Quarter 2022 Earnings: Misses Expectations (Simply Wall St.) +19.62%
Nov-08-22 07:45PM	Alector (ALEC) Reports Q3 Loss, Lags Revenue Estimates (Zacks) -19.81%
04:05PM	Alector Reports Third Quarter 2022 Financial Results and Provides Business Update (GlobeNewswire)
Nov-07-22 07:00AM	Alector to Participate in Upcoming Healthcare Conferences (GlobeNewswire)
Nov-04-22 11:05AM	Alector (NASDAQ:ALEC) investors are sitting on a loss of 65% if they invested a year ago (Simply Wall St.)
Nov-03-22 04:30PM	Alector Reports Inducement Grants under Nasdaq Listing Rule 5635(c)(4) (GlobeNewswire)
Oct-13-22 08:00AM	Alector Announces Promotion of Clare Hunt to Chief People Officer (GlobeNewswire)

Alector, Inc. operates as a clinical-stage biopharmaceutical company, which engages in pioneering of immuno-neurology. It develops portfolio of innate immune system programs, designed to functionally repair genetic mutations and enable the rejuvenated immune cells to counteract emerging brain pathologies. Its treatment targets immune dysfunction as a root cause of multiple pathologies that are drivers of degenerative brain disorders. The company was founded by Asa Abeliovich, Errik B. Anderson, Tillman U. Gerngross, and Arnon Rosenthal in May 2013 and is headquartered in South San Francisco, CA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Kenkare-Mitra Sara	President and Head of R&D	Mar 03 '25	Sale	1.47	29,073	42,662	536,142	Mar 05 04:05 PM
Rosenthal Arnon	Chief Executive Officer	Mar 03 '25	Sale	1.47	40,330	59,176	2,466,744	Mar 05 04:05 PM
GRASSO MARC	Chief Financial Officer	Mar 03 '25	Sale	1.47	18,091	26,547	312,560	Mar 05 04:05 PM
Romano Gary	Chief Medical Officer	Mar 03 '25	Sale	1.47	16,306	23,927	332,977	Mar 05 04:05 PM
Arnon Rosenthal	Officer	Mar 03 '25	Proposed Sale	1.64	50,242	82,397		Feb 28 05:05 PM
Gary Romano	Officer	Mar 03 '25	Proposed Sale	1.64	14,306	23,462		Feb 28 05:05 PM
Sara Kenkare-Mitra	Officer	Mar 03 '25	Proposed Sale	1.64	25,516	41,846		Feb 28 05:05 PM
Marc Grasso	Officer	Mar 03 '25	Proposed Sale	1.64	15,873	26,032		Feb 28 05:05 PM
GRASSO MARC	Chief Financial Officer	Dec 02 '24	Sale	2.52	16,489	41,542	330,651	Dec 03 05:40 PM
Rosenthal Arnon	Chief Executive Officer	Dec 02 '24	Sale	2.52	52,172	131,442	2,507,074	Dec 03 05:40 PM
Kenkare-Mitra Sara	President and Head of R&D	Dec 02 '24	Sale	2.52	26,500	66,764	565,215	Dec 03 05:40 PM
Romano Gary	Chief Medical Officer	Dec 02 '24	Sale	2.52	14,892	37,519	349,283	Dec 03 05:40 PM
Gary Romano	Officer	Dec 02 '24	Proposed Sale	2.59	14,306	37,053		Nov 29 03:00 PM
Sara Kenkare-Mitra	Officer	Dec 02 '24	Proposed Sale	2.59	25,465	65,954		Nov 29 03:00 PM
Marc Grasso	Officer	Dec 02 '24	Proposed Sale	2.59	15,842	41,031		Nov 29 03:00 PM
Arnon Rosenthal	Officer	Dec 02 '24	Proposed Sale	2.59	50,142	129,868		Nov 29 03:00 PM
GRASSO MARC	Chief Financial Officer	Sep 03 '24	Sale	4.88	7,297	35,620	130,740	Sep 04 04:44 PM
Rosenthal Arnon	Chief Executive Officer	Sep 03 '24	Sale	4.88	26,499	129,387	1,948,746	Sep 04 04:15 PM
Kenkare-Mitra Sara	President and Head of R&D	Sep 03 '24	Sale	4.88	13,926	67,981	291,715	Sep 04 04:15 PM
Romano Gary	Chief Medical Officer	Sep 03 '24	Sale	4.88	8,478	41,385	179,795	Sep 04 04:15 PM
Arnon Rosenthal	Officer	Sep 03 '24	Proposed Sale	5.28	24,359	128,616		Aug 30 05:18 PM
Sara Kenkare-Mitra	Officer	Sep 03 '24	Proposed Sale	5.28	12,796	67,563		Aug 30 05:18 PM
Marc Grasso	Officer	Sep 03 '24	Proposed Sale	5.28	6,703	35,392		Aug 30 05:18 PM
Gary Romano	Officer	Sep 03 '24	Proposed Sale	5.28	7,788	41,121		Aug 30 05:18 PM
SCHELLER RICHARD H	Director	Aug 22 '24	Sale	5.16	44,250	228,388	35,000	Aug 23 04:05 PM
SCHELLER RICHARD H	Director	Aug 22 '24	Proposed Sale	4.75	44,250	210,188		Aug 22 05:31 PM
Hammond Paula	Director	Aug 12 '24	Sale	5.06	10,500	53,179	60,209	Aug 13 07:55 PM
Yaffe Kristine	Director	Aug 12 '24	Sale	5.06	5,000	25,309	67,709	Aug 13 07:55 PM
PAULA HAMMOND	Director	Aug 12 '24	Proposed Sale	5.06	10,500	53,179		Aug 12 04:34 PM
Romano Gary	Chief Medical Officer	Jun 03 '24	Sale	4.80	8,040	38,582	188,273	Jun 04 06:05 PM
Kenkare-Mitra Sara	President and Head of R&D	Jun 03 '24	Sale	4.80	13,206	63,373	305,641	Jun 04 06:05 PM
Rosenthal Arnon	Chief Executive Officer	Jun 03 '24	Sale	4.80	25,135	120,618	1,975,245	Jun 04 06:05 PM
GRASSO MARC	Chief Financial Officer	Jun 03 '24	Sale	4.80	6,920	33,208	138,037	Jun 04 06:05 PM

Dollar change -0.16
Percentage change -5.61	%

CYCN Cyclerion Therapeutics Inc daily Stock Chart

Peers: SRPT BMRN EXEL BLUE NBIX TBPH CRBP VKTX RDUS PRQR

| Held by: VXF ONEQ

Index	-	P/E	-	EPS (ttm)	-1.22	Insider Own	39.54%	Shs Outstand	2.55M	Perf Week	6.75%
Market Cap	7.29M	Forward P/E	-	EPS next Y	-	Insider Trans	-25.05%	Shs Float	1.64M	Perf Month	5.49%
Income	-3.06M	PEG	-	EPS next Q	-	Inst Own	9.81%	Short Float	2.55%	Perf Quarter	-7.88%
Sales	2.00M	P/S	3.65	EPS this Y	-	Inst Trans	-51.95%	Short Ratio	0.02	Perf Half Y	5.53%
Book/sh	3.48	P/B	0.77	EPS next Y	-	ROA	-26.64%	Short Interest	0.04M	Perf Year	-12.67%
Cash/sh	1.19	P/C	2.26	EPS next 5Y	-	ROE	-30.36%	52W Range	1.27 - 9.47	Perf YTD	-16.46%
Dividend Est.	-	P/FCF	-	EPS past 5Y	57.72%	ROI	-34.54%	52W High	-71.59%	Beta	1.67
Dividend TTM	-	Quick Ratio	5.83	Sales past 5Y	-33.97%	Gross Margin	0.00%	52W Low	111.81%	ATR (14)	0.23
Dividend Ex-Date	-	Current Ratio	5.83	EPS Y/Y TTM	86.52%	Oper. Margin	-181.40%	RSI (14)	51.76	Volatility	7.45% 8.19%
Employees	1	Debt/Eq	0.00	Sales Y/Y TTM	-68.09%	Profit Margin	-152.85%	Recom	1.00	Target Price	80.00
Option/Short	No / Yes	LT Debt/Eq	0.00	EPS Q/Q	130.41%	Payout	-	Rel Volume	0.00	Prev Close	2.85
Sales Surprise	-13.92%	EPS Surprise	-3.33%	Sales Q/Q	-	Earnings	-	Avg Volume	1.90M	Price	2.69
SMA20	3.08%	SMA50	-5.12%	SMA200	-6.32%	Trades		Volume	2,481	Change	-5.61%

Date	Action	Analyst	Rating Change	Price Target Change
Oct-20-21	Initiated	Truist	Buy	$14
Sep-24-21	Initiated	Cantor Fitzgerald	Overweight	$7
Jun-03-19	Initiated	Credit Suisse	Neutral

Dec-17-24 08:08AM	Cyclerion's sGC Stimulator Portfolio Generates Revenues to Enable Company Growth (GlobeNewswire) -7.08%
Aug-07-24 07:00AM	Regina Graul, Ph.D., Promoted to Chief Executive Officer (GlobeNewswire)
Jun-21-24 07:52AM	Today's Biggest Pre-Market Stock Movers: 10 Top Gainers and Losers on Friday (InvestorPlace) +17.98%
May-08-24 08:52AM	CYCN Stock Earnings: Cyclerion Therapeutics Reported Results for Q1 2024 (InvestorPlace)
Apr-05-24 06:53AM	CYCN Stock Earnings: Cyclerion Therapeutics Reported Results for Q4 2023 (InvestorPlace)
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Mar-24-24 03:54PM	12 Best Biotech Penny Stocks to Invest In (Insider Monkey)
Dec-04-23 08:00AM	Cyclerion Appoints Regina Graul, Ph.D., as President (GlobeNewswire) -8.71%
Nov-30-23 06:16PM	Cyclerion Strengthens Board of Directors with Experienced Company Builder and Cutting-edge Innovator (GlobeNewswire) +7.39% +14.06%
Aug-02-23 08:39PM	The Petri Dish: Alexion buys Pfizer gene therapies in $1B deal; Peter Hecht's plan to save Cyclerion assets (American City Business Journals)
Jul-31-23 07:00AM	Tisento Launches with $81 Million From Top-Tier Investor Syndicate and Promising Cyclerion Assets (GlobeNewswire) +14.15%
Jun-01-23 04:00PM	Cyclerion Regains Compliance with Nasdaq Minimum Bid Price Requirement (GlobeNewswire)
May-15-23 01:00PM	Cyclerion Announces Reverse Stock Split (GlobeNewswire) -14.34%
May-12-23 02:59PM	Cyclerion Therapeutics to Sell Assets for $81M, CEO Transition To New Spin-Off Private Company Established By Shareholders, New Investors (Benzinga) -25.10%
May-11-23 06:00PM	Cyclerion Announces Definitive Agreement for Zagociguat and CY3018 (GlobeNewswire)
06:00PM	Cyclerion Announces Corporate Updates and Q1 2023 Financial Results (GlobeNewswire)
07:30AM	Loading…
Apr-03-23 07:30AM	Cyclerion Therapeutics Enters into Exclusive Negotiation Period and Binding Equity Investment Agreement (GlobeNewswire) -17.98%
Mar-27-23 07:00AM	Cyclerion Therapeutics Receives U.S. FDA Orphan Drug Designation for Zagociguat for the Treatment of Mitochondrial Diseases (GlobeNewswire) +23.71%
Mar-22-23 04:40PM	Cyclerion Reports Corporate Update and Full Year 2022 Financial Results (GlobeNewswire) -11.54%
Nov-22-22 07:00AM	Cyclerion Concludes Unsolicited Proposal Is Not in The Best Interest of The Company (GlobeNewswire) +34.31%
Nov-09-22 06:34AM	Cyclerion Therapeutics Third Quarter 2022 Earnings: US$0.24 loss per share (vs US$0.26 loss in 3Q 2021) (Simply Wall St.)
Oct-07-22 02:31PM	Cyclerion Therapeutics lays off nearly half of workforce (American City Business Journals) -9.66%
Oct-06-22 12:46PM	Cyclerion Shares Fall After Reprioritized Pipeline, Workforce Reduction (Benzinga) -37.57%
08:00AM	Cyclerion Announces Mitochondrial Disease-Focused Corporate Strategy (GlobeNewswire)
Aug-09-22 05:35PM	Cyclerion Therapeutics, Inc. (CYCN) Reports Q2 Loss, Misses Revenue Estimates (Zacks) -17.39%
04:00PM	Cyclerion Announces CY6463 Clinical Pipeline Progress and Second Quarter 2022 Financial Results (GlobeNewswire)
Aug-08-22 09:22AM	Is Cyclerion Therapeutics (NASDAQ:CYCN) In A Good Position To Invest In Growth? (Simply Wall St.) +27.76%
Jul-28-22 07:00AM	Cyclerion Therapeutics Announces Positive Topline Clinical Data for CY6463 in Patients with Cognitive Impairment Associated with Schizophrenia (CIAS) (GlobeNewswire) +22.08%
Jul-26-22 07:00AM	Steven E. Hyman, M.D., Appointed to Cyclerion Therapeutics Board of Directors (GlobeNewswire)
Jun-28-22 09:00AM	Cyclerion Therapeutics Provides Additional Positive CY6463 MELAS Clinical Data at a Webinar Hosted by United Mitochondrial Disease Foundation (GlobeNewswire) -5.55%
Jun-22-22 08:30AM	Cyclerion Therapeutics to Discuss CY6463 MELAS Clinical Data at a Webinar Hosted by United Mitochondrial Disease Foundation (GlobeNewswire)
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Jun-17-22 11:20AM	Cyclerion Neurology Candidate Shows Encouraging Action In Preclinical Studies (Benzinga)
08:00AM	Cyclerion Therapeutics Announces CY6463 Data Demonstrating Improved Cellular Energetics in Preclinical Models of Mitochondrial Disease (GlobeNewswire)
Jun-10-22 07:00AM	Cyclerion Therapeutics Announces Positive Topline Clinical Data for CY6463 in MELAS Patients at UMDF Mitochondrial Medicine 2022 Symposium (GlobeNewswire) -20.18%
Jun-06-22 07:00AM	Cyclerion Therapeutics to Share CY6463 MELAS Topline Study Results, CHOP to Present CY6463 Preclinical Data at UMDF Mitochondrial Medicine 2022 Symposium (GlobeNewswire) +8.58%
May-11-22 09:30AM	As Cyclerion Therapeutics, Inc. (NASDAQ:CYCN) drops to US$26m market cap, insiders might rethink their US$2.7m stock purchase earlier this year (Simply Wall St.) -8.17%
May-04-22 04:01PM	Cyclerion Announces CY6463 Clinical Pipeline Progress and First Quarter 2022 Financial Results (GlobeNewswire) +8.62% -5.39%
Feb-27-22 06:39AM	Is Cyclerion Therapeutics (NASDAQ:CYCN) In A Good Position To Deliver On Growth Plans? (Simply Wall St.)
Feb-24-22 04:01PM	Cyclerion Announces CY6463 Clinical Pipeline and Corporate Updates (GlobeNewswire)
Feb-23-22 08:00AM	Cyclerion Therapeutics and Ariana Pharma Announce an Artificial Intelligence-driven Precision Medicine Collaboration (GlobeNewswire)
Feb-01-22 05:30AM	CENTOGENE Announces Nomination of Andreas Busch to Supervisory Board (GlobeNewswire) +9.09%
Jan-26-22 08:00AM	Cyclerion Therapeutics Announces Initiation of Patient Dosing in CY6463 Phase 2a Study in Alzheimers Disease with Vascular Pathology (GlobeNewswire)
Dec-15-21 10:00AM	Down 38.9% in 4 Weeks, Here's Why You Should You Buy the Dip in Cyclerion Therapeutics, Inc. (CYCN) (Zacks) +9.38%
Nov-25-21 04:47AM	Cyclerion Therapeutics, Inc. (NASDAQ:CYCN) insider upped their holding by 67% earlier this year (Simply Wall St.)
Nov-11-21 05:32PM	Cyclerion Therapeutics to Participate in Jefferies London Healthcare Conference (GlobeNewswire)
Nov-09-21 04:01PM	Cyclerion Therapeutics Reports Third Quarter 2021 Financial Results and Corporate Update (GlobeNewswire) -5.42%
Nov-08-21 12:00PM	Exclusive: Startup raises $27M to find brain-based biomarkers (American City Business Journals)
Oct-20-21 04:24PM	Truist Bullish On This Clinical-Stage Biopharmaceutical Company With 374% Upside (Benzinga) +10.90% -5.42%
Oct-11-21 03:34AM	David Greenspans Slate Path Capital is Buying Coinbase, Stitch Fix, and More (Insider Monkey)
Oct-10-21 09:37AM	Is Cyclerion Therapeutics, Inc. (NASDAQ:CYCN) Popular Amongst Institutions? (Simply Wall St.)
Sep-22-21 08:00AM	Cyclerion Announces Publication of Preclinical Data Demonstrating Reduction in Neuroinflammation by Brain-Penetrant sGC Stimulator (GlobeNewswire)
Sep-08-21 08:00AM	Cyclerion Therapeutics to Participate in Two Upcoming Investor Conferences (GlobeNewswire)
Aug-26-21 07:19AM	Cyclerion Therapeutics (NASDAQ:CYCN) Has Debt But No Earnings; Should You Worry? (Simply Wall St.)
Aug-23-21 05:00PM	Cyclerion Therapeutics to Present at Annual Biomarkers for Alzheimers Disease Summit (GlobeNewswire) +8.16%
Jul-29-21 05:00PM	Cyclerion Therapeutics Reports Second Quarter 2021 Financial Results and Corporate Update (GlobeNewswire) -12.54%
Jul-22-21 04:30PM	Cyclerion Therapeutics to Present Clinical Trial Design for CY6463 Phase 2a Study in Participants with Alzheimers Disease with Vascular Pathology at the Alzheimers Association International Conference 2021 (AAIC) (GlobeNewswire) +14.72%
Jul-12-21 02:24AM	Cyclerion Therapeutics' (NASDAQ:CYCN) Shareholders Are Down 31% On Their Shares (Simply Wall St.)
Jul-09-21 06:14AM	Cyclerion Recruits Beacon Biosignals To Identify Disease-Relevant EEG Neurological Biomarkers (Benzinga)
Jul-08-21 07:22PM	Beacon Biosignals and Cyclerion Therapeutics Announce Strategic Partnership (PR Newswire)
04:30PM	Cyclerion Therapeutics and Beacon Biosignals Announce Expanded Strategic Partnership (GlobeNewswire)
Jun-04-21 10:27AM	Cyclerion Out-Licenses Praliciguat to Akebia, Announces $18M Capital Raise (Benzinga)
08:00AM	Cyclerion Therapeutics Announces Global Licensing Agreement with Akebia Therapeutics for Praliciguat (GlobeNewswire)
08:00AM	Cyclerion Therapeutics Announces $18 Million Private Placement (GlobeNewswire)
May-27-21 04:30PM	Cyclerion Therapeutics Announces Publication of CY6463 Preclinical Data in Frontiers in Pharmacology (GlobeNewswire) +5.25%
May-25-21 07:00AM	Cyclerion Therapeutics to Participate in Jefferies Virtual Healthcare Conference (GlobeNewswire)
May-09-21 03:36AM	The CEO & Director of Cyclerion Therapeutics, Inc. (NASDAQ:CYCN), Peter Hecht, Just Bought 309% More Shares (Simply Wall St.)
Apr-27-21 09:00AM	Cyclerion Therapeutics Hosted Webinar to Discuss Pipeline Progress (GlobeNewswire) -17.95%
Apr-26-21 07:00AM	Cyclerion Therapeutics Appoints Errol De Souza, Ph.D., to Board of Directors (GlobeNewswire) +7.22%
Apr-21-21 07:30AM	Cyclerion Therapeutics to Participate in the B. Riley Neuroscience Investor Conference (GlobeNewswire) +5.75%
Apr-20-21 07:00AM	Cyclerion Therapeutics to Host Pipeline Update Webinar (GlobeNewswire) +7.41%
Mar-24-21 04:05PM	TransMedics Appoints Stephanie Lovell to Board of Directors (PR Newswire) -6.80% +5.78%
Mar-22-21 02:23AM	Are Institutions Heavily Invested In Cyclerion Therapeutics, Inc.'s (NASDAQ:CYCN) Shares? (Simply Wall St.)
Mar-19-21 07:46AM	The Daily Biotech Pulse: Sarepta Gene Therapy Data, Idera Plunges On Failed Skin Cancer Study, 3 IPOs (Benzinga)
Mar-18-21 05:00PM	Cyclerion Therapeutics Announces Departure of Chief Medical Officer (GlobeNewswire)
Feb-25-21 07:00AM	Cyclerion Therapeutics Reports Full Year 2020 Financial Results and Corporate Update (GlobeNewswire) -9.48%
Jan-25-21 07:00AM	Cyclerion Therapeutics Announces Clinical and Scientific Advisory Boards (GlobeNewswire)
Jan-21-21 12:52AM	How Much Did Cyclerion Therapeutics'(NASDAQ:CYCN) Shareholders Earn From Share Price Movements Over The Last Year? (Simply Wall St.)
Jan-04-21 07:00AM	Cyclerion to Participate in the 39th Annual J.P. Morgan Healthcare Conference and H.C. Wainwright BioConnect Conference (GlobeNewswire)
Dec-21-20 07:30AM	Cyclerion Announces Leadership Transitions (GlobeNewswire)
Dec-02-20 11:27PM	Is Cyclerion Therapeutics, Inc. (CYCN) A Good Stock To Buy? (Insider Monkey)
Nov-15-20 07:55AM	Andreas Busch Is The Chief Innovation Officer of Cyclerion Therapeutics, Inc. (NASDAQ:CYCN) And They Just Picked Up 96% More Shares (Simply Wall St.)
Nov-05-20 07:00AM	Cyclerion Therapeutics Reports Third Quarter 2020 Financial Results and Recent Corporate Updates (GlobeNewswire)
Oct-14-20 01:09PM	Why Cyclerion Therapeutics Is Crashing Today (Motley Fool) -52.95%
10:07AM	Cyclerion Sinks As Biopharma Shelves Sickle Cell Disease Study (Benzinga)
07:00AM	Cyclerion Announces Positive Data from IW-6463 CNS Translational Pharmacology Study in Healthy Elderly Subjects (GlobeNewswire)
07:00AM	Cyclerion Announces Phase 2 STRONG-SCD Study Results in Patients with Sickle Cell Disease (GlobeNewswire)
Oct-04-20 09:52AM	Health Check: How Prudently Does Cyclerion Therapeutics (NASDAQ:CYCN) Use Debt? (Simply Wall St.)
Sep-04-20 07:00AM	Cyclerion to Participate at Upcoming September 2020 Investor Conferences (GlobeNewswire)
Aug-25-20 07:00AM	Cyclerion Announces Translational Research Award from the Alzheimers Association Part the Cloud-Gates Partnership Grant Program (GlobeNewswire) +11.09%
Aug-20-20 11:01AM	Is Cyclerion Therapeutics, Inc. (NASDAQ:CYCN) Popular Amongst Institutions? (Simply Wall St.)
Aug-03-20 09:25AM	Cyclerion Therapeutics Reports Second Quarter 2020 Financial Results and Recent Corporate Highlights (GlobeNewswire) +6.81%
Jul-30-20 09:00AM	Cyclerion Therapeutics Completes $24 Million Private Placement (GlobeNewswire) +12.50%
Jul-17-20 07:00AM	Cyclerion Therapeutics Presentation at Biomarkers in Alzheimers Disease Summit (GlobeNewswire)
Jul-06-20 03:17PM	We're A Little Worried About Cyclerion Therapeutics's (NASDAQ:CYCN) Cash Burn Rate (Simply Wall St.)
Jul-05-20 02:45PM	Should You Buy Cyclerion Therapeutics, Inc. (CYCN)? (Insider Monkey)
Jun-18-20 04:01PM	Cyclerion to Host Webcast Investor Event on July 9, 2020 (GlobeNewswire) +18.04%
May-22-20 07:52AM	The Cyclerion Therapeutics (NASDAQ:CYCN) Share Price Is Down 72% So Some Shareholders Are Rather Upset (Simply Wall St.) +6.45%
Apr-10-20 07:00AM	Cyclerion Updates Corporate Progress (GlobeNewswire)
Mar-23-20 06:50AM	Are Insiders Buying Cyclerion Therapeutics, Inc. (NASDAQ:CYCN) Stock? (Simply Wall St.) +18.94%
Jan-13-20 07:00AM	Cyclerion announces IW-6463 phase 1 healthy volunteer study results that support further development for neurodegenerative diseases (GlobeNewswire) +10.26%
Jan-12-20 05:05PM	The Week Ahead In Biotech: JPMorgan Healthcare Conference, FDA Panel Reviews Opioid Pain Drugs, I-Mab's IPO (Benzinga)

Cyclerion Therapeutics, Inc. is a clinical-stage biopharmaceutical company, which engages in the discovery, development, and commercialization of human therapeutics. Its product pipeline includes several sGC stimulators, small molecules that act synergistically with nitric oxide on sGC to boost production of cyclic guanosine monophosphate. The company was founded on September 6, 2018 and is headquartered in Cambridge, MA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Slate Path Capital LP	10% Owner	Nov 21 '24	Sale	1.55	357,880	555,108	0	Nov 25 04:05 PM

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