ALNY Alnylam Pharmaceuticals, Inc. Stock Quote

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ALNY [NASD]

Alnylam Pharmaceuticals, Inc.

Healthcare | Biotechnology | USA

statements

Index	-	P/E	-	EPS (ttm)	-7.57	Insider Own	0.30%	Shs Outstand	115.97M	Perf Week	-9.33%
Market Cap	15.57B	Forward P/E	-	EPS next Y	-4.90	Insider Trans	-47.72%	Shs Float	114.99M	Perf Month	-1.12%
Income	-846.20M	PEG	-	EPS next Q	-1.66	Inst Own	97.40%	Short Float	2.83%	Perf Quarter	-16.30%
Sales	345.20M	P/S	45.12	EPS this Y	-7.00%	Inst Trans	-0.12%	Short Ratio	7.07	Perf Half Y	-7.61%
Book/sh	12.18	P/B	10.82	EPS next Y	25.10%	ROA	-32.00%	Target Price	163.78	Perf Year	48.30%
Cash/sh	16.30	P/C	8.09	EPS next 5Y	46.09%	ROE	-58.40%	52W Range	83.06 - 167.33	Perf YTD	14.47%
Dividend	-	P/FCF	-	EPS past 5Y	-10.80%	ROI	-65.40%	52W High	-21.21%	Beta	1.51
Dividend %	-	Quick Ratio	5.40	Sales past 5Y	34.20%	Gross Margin	85.30%	52W Low	58.73%	ATR	4.82
Employees	1323	Current Ratio	5.60	Sales Q/Q	132.70%	Oper. Margin	-	RSI (14)	36.92	Volatility	4.03% 3.48%
Optionable	Yes	Debt/Eq	0.00	EPS Q/Q	22.80%	Profit Margin	-	Rel Volume	1.14	Prev Close	134.30
Shortable	Yes	LT Debt/Eq	0.00	Earnings	Nov 05 BMO	Payout	-	Avg Volume	460.95K	Price	131.84
Recom	2.00	SMA20	-7.53%	SMA50	-3.05%	SMA200	-0.31%	Volume	525,507	Change	-1.83%

Sep-30-20

Resumed

Berenberg

Hold

$145

Sep-08-20

Initiated

Citigroup

Buy

$170

Aug-11-20

Downgrade

Oppenheimer

Outperform → Perform

May-13-20

Initiated

RBC Capital Mkts

Sector Perform

$150

May-07-20

Downgrade

JP Morgan

Overweight → Neutral

$133 → $137

Apr-24-20

Resumed

Evercore ISI

Outperform

$160

Mar-19-20

Initiated

Berenberg

Buy

$200

Dec-19-19

Reiterated

Chardan Capital Markets

Buy

$150 → $190

Nov-20-19

Initiated

Oppenheimer

Outperform

$128

Nov-13-19

Initiated

BofA/Merrill

Buy

$110

May-23-19

Resumed

Goldman

Neutral

$80

Apr-12-19

Initiated

Evercore ISI

Outperform

Mar-06-19

Upgrade

Evercore ISI

In-line → Outperform

Mar-05-19

Upgrade

Morgan Stanley

Equal-Weight → Overweight

Jan-23-19

Initiated

UBS

Neutral

$87

Oct-01-18

Initiated

Cantor Fitzgerald

Overweight

$135

Aug-13-18

Reiterated

Stifel

Buy

$125 → $123

Aug-07-18

Upgrade

Stifel

Hold → Buy

$95 → $125

May-04-18

Reiterated

Stifel

Hold

$107 → $95

Mar-28-18

Initiated

Evercore ISI

In-line

Oct-22-20 04:00PM	Alnylam to Webcast Conference Call Discussing Third Quarter 2020 Financial Results Business Wire
12:33PM	Alnylam Pharmaceuticals (ALNY) Expected to Beat Earnings Estimates: Should You Buy? Zacks
10:00AM	Alnylam Presents Positive Results from ILLUMINATE-B Phase 3 Study in Pediatric Patients with Primary Hyperoxaluria Type 1 at the American Society of Nephrology Kidney Week Business Wire
Oct-19-20 12:46PM	Is Ionis Pharmaceuticals a Buy? Motley Fool
09:55AM	Alnylam (ALNY) Gets Positive CHMP Opinion for Lumasiran Zacks
Oct-18-20 06:43AM	Can Either of These Little-Known Biotechs Find New Life Fighting Coronavirus? Motley Fool
Oct-16-20 06:00AM	Alnylam Receives Positive CHMP Opinion for OXLUMO (lumasiran) for the Treatment of Primary Hyperoxaluria Type 1 in All Age Groups Business Wire
Oct-15-20 04:12PM	Vertex Tumbles As It Stops Testing On Protein Deficiency Treatment Investor's Business Daily
Oct-11-20 08:33AM	When Will Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) Turn A Profit? Simply Wall St.
Oct-01-20 10:50AM	Alnylam Releases Positive Top-Line Rare Disease Lumasiran Data Zacks
Sep-30-20 04:19PM	Alnylam Pharmaceuticals Posts Positive Results For Its Treatment For Rare Disease Investor's Business Daily
07:00AM	Alnylam Reports Positive Topline Results from ILLUMINATE-B Phase 3 Study of Lumasiran for the Treatment of Primary Hyperoxaluria Type 1 in Children Under the Age of Six Business Wire
Sep-28-20 04:00PM	Alnylam to Webcast Presentation at Chardan Virtual 4th Annual Genetic Medicines Conference Business Wire
Sep-16-20 04:24PM	Arrowhead Pharma Reveals Positive Data On Drug To Treat Liver Disease; ARWR Stock Jumps Investor's Business Daily
Sep-09-20 09:47PM	Hedge Funds Have Never Been This Bullish On Alnylam Pharmaceuticals, Inc. (ALNY) Insider Monkey
06:29AM	3 Healthcare Stocks I Can't Wait to Buy When the Stock Market Tanks Again Motley Fool
Sep-05-20 11:32AM	Why Is Alnylam (ALNY) Down 14.8% Since Last Earnings Report? Zacks
Sep-04-20 06:35PM	Analyst Report: Alnylam Pharmaceuticals, Inc. Morningstar Research
Sep-03-20 07:30AM	Alnylam Highlights Prospects for Building an Industry-Leading ATTR Amyloidosis Franchise at RNAi Roundtable Business Wire
Sep-02-20 08:00AM	Alnylam to Webcast Presentations at Upcoming September Investor Conferences Business Wire
Aug-27-20 10:17AM	Alnylam's Share Price Rises YTD on Pipeline Developments Zacks
08:13AM	Here's What We Learned About The CEO Pay At Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) Simply Wall St.
Aug-17-20 07:30AM	Blackstone and Alnylam Close $150 Million R&D Financing to Advance RNAi Therapeutics for Cardiovascular Disease Business Wire
Aug-07-20 10:56AM	Alnylam (ALNY) Beats on Q2 Earnings, Narrows Sales Guidance Zacks
Aug-06-20 11:25AM	Alnylam Pharmaceuticals (ALNY) Reports Q2 Loss, Tops Revenue Estimates Zacks
08:00AM	Alnylam Pharmaceuticals Reports Second Quarter 2020 Financial Results and Highlights Recent Period Activity Business Wire
07:30AM	Alnylam Announces Planned Transition of Barry Greene, President Business Wire
Aug-03-20 07:30AM	Alnylam Submits CTA Application for ALN-HSD, an Investigational RNAi Therapeutic for the Treatment of Nonalcoholic Steatohepatitis (NASH) Business Wire
Jul-30-20 12:33PM	Alnylam Pharmaceuticals (ALNY) May Report Negative Earnings: Know the Trend Ahead of Next Week's Release Zacks
Jul-23-20 11:02AM	A Top Contender in the Race for a NASH Drug Drops Out Barrons.com
08:00AM	Alnylam to Webcast Conference Call Discussing Second Quarter 2020 Financial Results Business Wire
Jul-14-20 12:00PM	Alnylam (ALNY) Upgraded to Buy: Here's Why Zacks
Jul-13-20 10:45AM	Are Investors Undervaluing Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) By 34%? Simply Wall St. -5.86%
07:28AM	Alnylam Announces that the United Kingdoms MHRA Grants Early Access to Lumasiran Business Wire
Jul-09-20 08:54PM	Did Hedge Funds Make The Right Call On Alnylam Pharmaceuticals, Inc. (ALNY) ? Insider Monkey
Jul-08-20 07:57AM	Alnylam Pharmaceuticals and Taiba Group Partner to Commercialize RNAi Therapeutics in the Gulf States Business Wire
Jul-01-20 11:48AM	Alnylam Pharma Poised to Shoot Higher TheStreet.com
07:00AM	FOCUS-From Parkinson's to peanut allergy, pandemic puts brakes on new drugs Reuters
Jun-30-20 09:00AM	Alnylam Reports New 12-Month Interim Data From the ENVISION Phase 3 Study of Givosiran in Acute Hepatic Porphyria Business Wire
Jun-28-20 04:51PM	New Pharma ETF Focuses on Testing and Treatment for Infectious Diseases--but Not Covid-19 GuruFocus.com
Jun-18-20 07:00AM	Alnylam to Host Seventh Annual "RNAi Roundtable" Webcast Series Business Wire
Jun-17-20 04:00PM	Alnylam to Webcast Presentation at Bank of America Securities 2020 Napa Biopharma Conference Business Wire
09:50AM	Alnylam???s Share Price Rises YTD on Pipeline Developments Zacks
Jun-10-20 05:07PM	Alnylam Announces Publication of ENVISION Phase 3 Study Results for Givosiran in the New England Journal of Medicine Business Wire
Jun-08-20 10:00AM	Alnylam Reports Positive Phase III Results on Lumasarin Zacks
09:00AM	Pfizer Is Charging Ahead With A Coronavirus Vaccine Is PFE Stock A Buy? Investor's Business Daily
03:24AM	Alnylam Reveals Solid Lumasiran Results; Analyst Says Dicerna Better Pick SmarterAnalyst
Jun-07-20 07:15AM	Alnylam Presents Positive Phase 3 Results from ILLUMINATE-A Study of Lumasiran, an Investigational RNAi Therapeutic for Treatment of Primary Hyperoxaluria Type 1 Business Wire
Jun-05-20 11:32AM	Why Is Alnylam (ALNY) Down 6.8% Since Last Earnings Report? Zacks
Jun-04-20 03:54PM	Alnylam Pharmaceuticals, Inc. (ALNY): Hedge Funds Are Getting Bullish Insider Monkey
Jun-02-20 08:00AM	Alnylam Announces Recipients of Second Annual Advocacy for Impact Grants Program Business Wire
Jun-01-20 07:00AM	Alnylam to Webcast Conference Call Discussing Full Results from ILLUMINATE-A Phase 3 Study of Lumasiran at ERA-EDTA International Congress Business Wire
May-27-20 09:47AM	Alnylam's (ALNY) Lumasiran NDA Gets Priority Review From FDA Zacks
May-26-20 04:00PM	Alnylam to Webcast Presentations at Upcoming June Investor Conferences Business Wire
07:00AM	Edited Transcript of ALNY earnings conference call or presentation 6-May-20 12:30pm GMT Thomson Reuters StreetEvents
07:00AM	Alnylam Announces U.S. Food and Drug Administration Has Granted Priority Review of the Lumasiran New Drug Application for the Treatment of Primary Hyperoxaluria Type 1 Business Wire
May-25-20 11:30AM	Is Alnylam Pharmaceuticals (ALNY) Outperforming Other Medical Stocks This Year? Zacks
May-22-20 12:30PM	Alnylam Presents New Long-Term Results from Global Open-Label Extension Study of ONPATTRO® (patisiran) at the European Academy of Neurology Virtual Congress 2020 Business Wire
May-21-20 07:03AM	Is Alnylam Pharmaceuticals a Buy? Motley Fool
May-12-20 04:01PM	Vir Biotechnology Provides Corporate Update and Reports First Quarter 2020 Financial Results GlobeNewswire
May-11-20 10:46AM	How Alnylam (ALNY) Stock Stands Out in a Strong Industry Zacks
08:00AM	Alnylam to Webcast Presentations at Upcoming May Investor Conferences Business Wire
May-07-20 12:00PM	What Makes Alnylam (ALNY) a New Buy Stock Zacks
11:30AM	Is Alnylam Pharmaceuticals (ALNY) Outperforming Other Medical Stocks This Year? Zacks
10:25AM	Alnylam (ALNY) Beats on Q1 Earnings, Cuts Onpattro Sales View Zacks
May-06-20 06:30PM	Alnylam Pharmaceuticals Inc (ALNY) Q1 2020 Earnings Call Transcript Motley Fool
01:27PM	Alnylam Pharmaceuticals Lowers 2020 Sales Expectations Due to COVID-19 Motley Fool
09:25AM	Alnylam Pharmaceuticals (ALNY) Reports Q1 Loss, Tops Revenue Estimates Zacks
08:00AM	Alnylam Pharmaceuticals Reports First Quarter 2020 Financial Results and Highlights Recent Period Activity Business Wire
May-05-20 11:45AM	Drug/Biotech Stock Q1 Earnings Due on May 6: ZTS, ALXN & More Zacks
11:40AM	5 Drug/Biotech Stocks Set to Outpace Q1 Earnings Estimates Zacks
10:40AM	Is a Surprise Coming for Alnylam Pharmaceuticals (ALNY) This Earnings Season? Zacks
May-04-20 10:23AM	Vir Biotechnology and Alnylam Pick a Coronavirus Vaccine Candidate to Pursue Motley Fool +5.94%
08:24AM	Vir, Alnylam identify COVID-19 therapy candidate, plan human trials by year end Reuters
07:46AM	Vir, Alnylam pick coronavirus therapy candidate, plan human trials by year end Reuters
07:30AM	Vir and Alnylam Identify RNAi Therapeutic Development Candidate, VIR-2703 (ALN-COV), Targeting SARS-CoV-2 for the Treatment of COVID-19 Business Wire
May-03-20 08:37AM	If You Had Bought Alnylam Pharmaceuticals (NASDAQ:ALNY) Stock Three Years Ago, You Could Pocket A 134% Gain Today Simply Wall St.
Apr-29-20 12:34PM	Alnylam Pharmaceuticals (ALNY) Expected to Beat Earnings Estimates: Should You Buy? Zacks
Apr-23-20 08:00AM	Alnylam to Webcast Conference Call Discussing First Quarter 2020 Financial Results Business Wire
Apr-17-20 04:23PM	Blackstones Byron Wien Weighs In on Employment, China, and the Health-Care System Barrons.com +8.42%
Apr-16-20 06:35AM	These Mass. companies are developing COVID-19 treatments and tests American City Business Journals +5.12%
Apr-15-20 04:01PM	VIR-2218 Demonstrates Dose-Dependent and Durable Reductions of Hepatitis B Surface Antigen in Phase 1/2 Trial GlobeNewswire
11:15AM	Alnylam's Vutrisiran Gets Fast Track Tag for hATTR Amyloidosis Zacks
Apr-14-20 10:06AM	Alnylam's $2B Deal With Blackstone to Boost Drug Development Zacks
07:00AM	Alnylam Receives Fast Track Designation for Vutrisiran for the Treatment of the Polyneuropathy of hATTR Amyloidosis Business Wire
Apr-13-20 04:00PM	Alnylam to Webcast Presentation at 19th Annual Needham Virtual Healthcare Conference Business Wire
02:57PM	Alnylam plans Cambridge expansion after $2B investment American City Business Journals
07:46AM	Blackstone invests $2 billion in Alnylam, boosting gene-silencing drug development Reuters
07:43AM	Alnylam Rises on $2 Billion Blackstone Investment TheStreet.com
07:41AM	Blackstone invests $2 bln in Alnylam Pharma Reuters
07:35AM	Alnylam's stock surges after Blackstone confirms $2 billion investment MarketWatch
07:30AM	Blackstone and Alnylam Enter Into $2 Billion Strategic Financing Collaboration to Accelerate the Advancement of RNAi Therapeutics Business Wire
01:23AM	Blackstone/Alnylam: royalty flush Financial Times
Apr-08-20 11:19AM	Vir Biotech Adds Glaxo to List of Covid-19 Partners GuruFocus.com
10:24AM	Alnylam (ALNY) Completes Rolling Submission of Lumasiran NDA Zacks
10:05AM	Biotech Stock Roundup: AMGN & INCY Focus on Coronavirus Treatments, & More Zacks
Apr-07-20 07:00AM	Alnylam Completes Rolling Submission of New Drug Application to the U.S. Food and Drug Administration and Submits Marketing Authorization Application to the European Medicines Agency for Lumasiran for the Treatment of Primary Hyperoxaluria Type 1 Business Wire
Apr-06-20 06:26PM	Alnylam, Dicerna Join Forces to Take on Arrowhead GuruFocus.com +5.97%
10:30AM	Former gene-silencing rivals bury the hatchet with new partnership American City Business Journals
07:00AM	Alnylam and Dicerna Form RNAi Therapeutics Collaboration on Alpha-1 Antitrypsin Deficiency-Associated Liver Disease and Complete Cross-License Agreement for Primary Hyperoxaluria Programs Business Wire

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing, and commercializing RNA interference (RNAi) therapeutics. The company's pipeline of investigational RNAi therapeutics focus on genetic medicines, cardio-metabolic diseases, hepatic infectious diseases, and central nervous system/ocular diseases. Its marketed products include ONPATTRO (patisiran), a lipid complex injection for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults; and GIVLAARI for the treatment of adults with acute hepatic porphyria (AHP). In addition, the company is developing givosiran for the treatment of patients with AHP; lumasiran for the treatment of primary hyperoxaluria type 1, or PH1; patisiran for the treatment of transthyretin amyloidosis, or ATTR amyloidosis, with cardiomyopathy; and vutrisiran for the treatment of ATTR amyloidosis. Alnylam Pharmaceuticals, Inc. has strategic alliances primarily with Sanofi Genzyme; The Medicines Company; Ionis Pharmaceuticals, Inc.; and Regeneron Pharmaceuticals, Inc., as well as collaboration with Vir Biotechnology, Inc. to advance RNAi therapeutics for the treatment of coronavirus infection, including COVID-19. It also has a collaboration and license agreement with Dicerna Pharmaceuticals, Inc. to develop and commercialize investigational ribonucleic acid interference therapeutics for the treatment of alpha-1 antitrypsin deficiency-associated liver disease, as well as Vir Biotechnology, Inc. to develop and commercialize RNAi therapeutics. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Vaishnaw Akshay	President, R&D	Sep 29	Option Exercise	42.22	971	40,996	15,090	Oct 01 04:03 PM
Vaishnaw Akshay	President, R&D	Sep 29	Sale	140.00	971	135,940	14,119	Oct 01 04:03 PM
Greene Barry E	President	Sep 09	Option Exercise	9.14	44,530	407,004	114,873	Sep 11 05:11 PM
Greene Barry E	President	Sep 09	Sale	123.23	44,530	5,487,594	70,343	Sep 11 05:11 PM
MARAGANORE JOHN	Chief Executive Officer	Aug 20	Option Exercise	9.14	34,765	317,752	232,354	Aug 21 04:06 PM
MARAGANORE JOHN	Chief Executive Officer	Aug 20	Sale	136.13	34,765	4,732,542	197,589	Aug 21 04:06 PM
Greene Barry E	President	Aug 10	Option Exercise	70.95	4,931	349,871	67,167	Aug 11 04:09 PM
KEATING LAURIE	EVP, Chief Legal Officer	Jul 13	Option Exercise	87.16	35,750	3,116,066	50,242	Jul 14 04:03 PM
KEATING LAURIE	EVP, Chief Legal Officer	Jul 13	Sale	160.67	47,250	7,591,790	2,992	Jul 14 04:03 PM
Greenstreet Yvonne	Chief Operating Officer	Jul 10	Option Exercise	77.10	46,639	3,595,867	51,459	Jul 14 04:02 PM
Greenstreet Yvonne	Chief Operating Officer	Jul 10	Sale	161.00	46,639	7,508,879	4,820	Jul 14 04:02 PM
Greenstreet Yvonne	Chief Operating Officer	Jul 09	Option Exercise	43.14	11,236	484,743	16,056	Jul 10 04:03 PM
Greenstreet Yvonne	Chief Operating Officer	Jul 09	Sale	161.00	11,236	1,808,996	4,820	Jul 10 04:03 PM
Greene Barry E	President	Jul 07	Option Exercise	9.14	22,265	203,502	84,501	Jul 09 04:02 PM
Greene Barry E	President	Jul 07	Sale	159.99	22,265	3,562,177	62,236	Jul 09 04:02 PM
Vaishnaw Akshay	President, R&D	Jun 22	Option Exercise	42.22	970	40,953	15,089	Jun 24 04:02 PM
Vaishnaw Akshay	President, R&D	Jun 22	Sale	151.07	970	146,536	14,119	Jun 24 04:02 PM
MARAGANORE JOHN	Chief Executive Officer	May 20	Option Exercise	9.14	34,765	317,752	232,354	May 22 04:03 PM
MARAGANORE JOHN	Chief Executive Officer	May 20	Sale	143.22	34,765	4,978,983	197,589	May 22 04:03 PM
Greenstreet Yvonne	Chief Operating Officer	May 06	Option Exercise	77.10	50,000	3,855,000	54,820	May 07 04:08 PM
Greene Barry E	President	May 06	Option Exercise	9.14	22,265	203,502	84,501	May 07 04:09 PM
Greene Barry E	President	May 06	Sale	149.99	22,265	3,339,527	62,236	May 07 04:09 PM
Greenstreet Yvonne	Chief Operating Officer	May 06	Sale	150.00	50,000	7,500,000	4,820	May 07 04:08 PM
Greenstreet Yvonne	Chief Operating Officer	May 05	Option Exercise	42.22	7,811	329,780	12,631	May 07 04:08 PM
Greenstreet Yvonne	Chief Operating Officer	May 05	Sale	140.00	7,811	1,093,540	4,820	May 07 04:08 PM
KEATING LAURIE	EVP, Chief Legal Officer	Apr 20	Option Exercise	77.40	10,000	774,000	24,492	Apr 22 04:07 PM
Vaishnaw Akshay	President, R&D	Apr 20	Option Exercise	42.22	21,971	927,616	36,090	Apr 22 04:06 PM
Vaishnaw Akshay	President, R&D	Apr 20	Sale	140.00	21,971	3,075,940	14,119	Apr 22 04:06 PM
KEATING LAURIE	EVP, Chief Legal Officer	Apr 20	Sale	139.00	10,000	1,390,000	14,492	Apr 22 04:07 PM
MARAGANORE JOHN	Chief Executive Officer	Feb 20	Option Exercise	9.14	34,765	317,752	224,758	Feb 21 04:02 PM
MARAGANORE JOHN	Chief Executive Officer	Feb 20	Sale	131.85	34,765	4,583,674	189,993	Feb 21 04:02 PM
SHARP PHILLIP A	Director	Feb 12	Option Exercise	12.48	30,000	374,400	265,633	Feb 13 04:06 PM
SHARP PHILLIP A	Director	Feb 12	Sale	130.00	30,000	3,900,000	235,633	Feb 13 04:06 PM
Greenstreet Yvonne	Chief Operating Officer	Feb 10	Option Exercise	42.22	5,600	236,432	11,808	Feb 11 04:08 PM
PAUL STEVEN M	Director	Feb 10	Option Exercise	14.67	30,000	440,100	31,000	Feb 11 04:08 PM
KEATING LAURIE	EVP, Chief Legal Officer	Feb 10	Option Exercise	77.40	10,000	774,000	22,258	Feb 12 04:03 PM
Greenstreet Yvonne	Chief Operating Officer	Feb 10	Sale	130.00	9,892	1,285,960	1,916	Feb 11 04:08 PM
KEATING LAURIE	EVP, Chief Legal Officer	Feb 10	Sale	129.00	10,000	1,290,000	12,258	Feb 12 04:03 PM
PAUL STEVEN M	Director	Feb 10	Sale	130.00	30,000	3,900,000	1,000	Feb 11 04:08 PM
Vaishnaw Akshay	President, R&D	Feb 07	Option Exercise	42.22	22,750	960,505	34,923	Feb 11 04:08 PM
Greenstreet Yvonne	Chief Operating Officer	Feb 07	Option Exercise	42.22	6,250	263,875	12,458	Feb 11 04:08 PM
Greenstreet Yvonne	Chief Operating Officer	Feb 07	Sale	123.90	6,250	774,375	6,208	Feb 11 04:08 PM
Vaishnaw Akshay	President, R&D	Feb 07	Sale	125.00	23,708	2,963,500	11,215	Feb 11 04:08 PM
KEATING LAURIE	EVP, Chief Legal Officer	Jan 29	Option Exercise	77.40	6,337	490,484	14,932	Jan 31 04:05 PM
KEATING LAURIE	EVP, Chief Legal Officer	Jan 29	Sale	119.00	6,337	754,103	8,595	Jan 31 04:05 PM
KEATING LAURIE	EVP, Chief Legal Officer	Jan 27	Option Exercise	42.22	34,374	1,451,270	49,632	Jan 29 04:03 PM
KEATING LAURIE	EVP, Chief Legal Officer	Jan 27	Sale	117.70	41,037	4,829,970	8,595	Jan 29 04:03 PM
Greenstreet Yvonne	Chief Operating Officer	Nov 20	Option Exercise	42.22	8,404	354,817	10,320	Nov 22 04:05 PM
Fanucci Marsha	Director	Nov 20	Option Exercise	13.80	75,000	1,035,000	75,000	Nov 22 04:06 PM
Greenstreet Yvonne	Chief Operating Officer	Nov 20	Sale	105.00	8,404	882,420	1,916	Nov 22 04:05 PM
Fanucci Marsha	Director	Nov 20	Sale	100.00	75,000	7,500,000	0	Nov 22 04:06 PM
SHARP PHILLIP A	Director	Nov 18	Option Exercise	16.43	15,000	246,450	250,633	Nov 20 04:17 PM
SHARP PHILLIP A	Director	Nov 18	Sale	91.71	15,000	1,375,662	235,633	Nov 20 04:17 PM

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