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APLT

Applied Therapeutics Inc

Dec 13 • 04:00PM ET

1.15

Dollar change +0.01
Percentage change 0.88	%

Healthcare • Biotechnology • USA • NASD

Peers: GILD VRTX REGN BMRN ALNY IONS ACAD NBIX RARE KPTI

| Held by: VTI VXF VTWO SURI IWM XBI VFMO DWAS IWO VTWG

Scroll to Statements

Index	RUT	P/E	-	EPS (ttm)	-1.32	Insider Own	25.00%	Shs Outstand	116.36M	Perf Week	-10.16%
Market Cap	134.98M	Forward P/E	-	EPS next Y	-0.61	Insider Trans	-2.70%	Shs Float	87.26M	Perf Month	-87.11%
Income	-96.51M	PEG	-	EPS next Q	-0.20	Inst Own	88.02%	Short Float	16.25%	Perf Quarter	-75.48%
Sales	10.66M	P/S	12.66	EPS this Y	1.41%	Inst Trans	14.27%	Short Ratio	2.55	Perf Half Y	-77.23%
Book/sh	0.05	P/B	22.71	EPS next Y	56.22%	ROA	-189.48%	Short Interest	14.18M	Perf Year	-61.67%
Cash/sh	0.84	P/C	1.37	EPS next 5Y	-	ROE	-	52W Range	1.12 - 10.62	Perf YTD	-65.67%
Dividend Est.	-	P/FCF	-	EPS past 5Y	-8.72%	ROI	-1270.08%	52W High	-89.18%	Beta	1.74
Dividend TTM	-	Quick Ratio	1.06	Sales past 5Y	0.00%	Gross Margin	95.68%	52W Low	3.14%	ATR (14)	0.65
Dividend Ex-Date	-	Current Ratio	1.06	EPS Y/Y TTM	59.67%	Oper. Margin	-586.31%	RSI (14)	17.81	Volatility	12.24% 12.45%
Employees	25	Debt/Eq	0.33	Sales Y/Y TTM	-	Profit Margin	-905.38%	Recom	1.83	Target Price	5.00
Option/Short	Yes / Yes	LT Debt/Eq	0.29	EPS Q/Q	-26.99%	Payout	-	Rel Volume	1.29	Prev Close	1.14
Sales Surprise	-	EPS Surprise	-203.80%	Sales Q/Q	-	Earnings	Nov 07 BMO	Avg Volume	5.56M	Price	1.15
SMA20	-76.62%	SMA50	-84.30%	SMA200	-80.77%	Trades		Volume	7,167,948	Change	0.88%

Date	Action	Analyst	Rating Change	Price Target Change
Dec-02-24	Downgrade	UBS	Buy → Neutral	$13 → $2
Nov-29-24	Downgrade	RBC Capital Mkts	Outperform → Sector Perform	$12 → $4
Jul-31-24	Initiated	William Blair	Outperform
Mar-26-24	Initiated	RBC Capital Mkts	Outperform	$12
Feb-22-24	Initiated	Leerink Partners	Outperform	$12
Jan-04-22	Downgrade	Barclays	Overweight → Equal Weight	$44 → $7
Aug-27-21	Downgrade	Goldman	Neutral → Sell	$16 → $10
Jun-25-21	Resumed	Goldman	Neutral	$18
Oct-08-20	Initiated	Truist	Buy	$85
Apr-22-20	Initiated	Goldman	Buy	$60
Feb-27-20	Initiated	Barclays	Overweight	$64
Jun-10-19	Initiated	Robert W. Baird	Outperform	$24
Jun-10-19	Initiated	Cowen	Outperform
Jun-10-19	Initiated	Citigroup	Buy	$29

Show Previous Ratings

Nov-30-24 06:40AM	Applied Therapeutics CRL a major setback, says William Blair (TipRanks)
05:30AM	Applied Therapeutics downgraded to Sector Perform from Outperform at RBC (TipRanks)
Nov-29-24 03:56PM	FDA Rejects Applied Therapeutics' NDA for Govorestat, Citing Flaws; Shares Plunge 76% (GuruFocus.com) -76.31%
10:49AM	Top Stock Movers Now: Hasbro, MicroStrategy, Super Micro Computer, and More (Investopedia)
10:48AM	Applied Therapeutics Stock Plummets 73%. The FDA Delivers This Crushing Blow. (Barrons.com)
10:06AM	Loading…
10:06AM	Applied Therapeutics Stock Plummets After FDA Rejects Metabolic Disease Drug (Investopedia)
08:46AM	RBC downgrades Applied Therapeutics as FDA rejects Govorestat, hacks price target (Investing.com)
Nov-28-24 07:02AM	Wait for galactosemia therapy goes on after FDA shuns Applied Therapeutics govorestat (Pharmaceutical Technology)
Nov-27-24 04:10PM	Applied Therapeutics Receives Complete Response Letter from U.S. FDA Regarding New Drug Application for Govorestat for Classic Galactosemia (GlobeNewswire) -16.06% -76.31%
Nov-07-24 07:00AM	Applied Therapeutics Reports Third Quarter 2024 Financial Results (GlobeNewswire)
Nov-05-24 07:00AM	Applied Therapeutics to Present at the 2024 UBS Global Healthcare Conference (GlobeNewswire)
Oct-29-24 12:00PM	Applied Therapeutics (APLT) Upgraded to Buy: Here's What You Should Know (Zacks)
09:40AM	Is Applied Therapeutics (APLT) Outperforming Other Medical Stocks This Year? (Zacks)
Oct-10-24 09:40AM	Are Medical Stocks Lagging Applied Therapeutics (APLT) This Year? (Zacks)
Sep-24-24 09:40AM	Is Applied Therapeutics (APLT) Stock Outpacing Its Medical Peers This Year? (Zacks) +5.53%
12:00PM	Loading…
Sep-23-24 12:00PM	All You Need to Know About Applied Therapeutics (APLT) Rating Upgrade to Buy (Zacks)
Sep-18-24 10:56AM	Why Applied Therapeutics Stock Is Skyrocketing Today (Motley Fool) +68.82%
10:52AM	Applied Therapeutics Stock Soars As FDA Scraps Panel Meeting For Its Inherited Metabolic Disorder Drug (Benzinga)
07:00AM	Applied Therapeutics Provides Regulatory Update on Govorestat for the Treatment of Classic Galactosemia (GlobeNewswire)
Sep-04-24 07:00AM	Applied Therapeutics to Participate in Upcoming Investor Conferences (GlobeNewswire)
Aug-07-24 07:00AM	Applied Therapeutics Reports Second Quarter 2024 Financial Results (GlobeNewswire)
Jul-31-24 02:37PM	Rare Disease-Focused Applied Therapeutics' Lead Candidate Govorestat Has Blockbuster Potential, Analyst Sees 140% Stock Upside (Benzinga) +19.28%
Jul-01-24 07:00AM	Applied Therapeutics Added to Russell 3000 Index (GlobeNewswire)
Jun-29-24 08:50PM	Why Is Applied Therapeutics, Inc. (APLT) the Best Biotech Penny Stock to Buy Now? (Insider Monkey)
May-10-24 02:47PM	Applied Therapeutics Inc (APLT) Reports Q1 2024 Earnings: A Deep Dive into Financials and ... (GuruFocus.com)
May-09-24 01:55PM	APLT Stock Earnings: Applied Therapeutics Meets EPS, Misses Revenue for Q1 2024 (InvestorPlace)
07:00AM	Applied Therapeutics Reports First Quarter 2024 Financial Results (GlobeNewswire)
May-07-24 07:00AM	Applied Therapeutics to Present at the 2024 RBC Capital Markets Global Healthcare Conference (GlobeNewswire)
Apr-15-24 07:00AM	Applied Therapeutics Appoints Dale Hooks as Chief Commercial Officer (GlobeNewswire)
Apr-04-24 07:00AM	Applied Therapeutics to Present Results from Phase 3 ARISE-HF Study in Diabetic Cardiomyopathy at ACC 2024 (GlobeNewswire)
05:12PM	Loading…
Mar-28-24 05:12PM	UPDATE 1-US FDA extends review of Applied Therapeutics' genetic disease drug (Reuters) -6.91%
04:42PM	US FDA extends review of Applied Therapeutics' genetic disease drug (Reuters)
04:30PM	Applied Therapeutics Provides FDA Update on PDUFA Target Action Date for Govorestat for the Treatment of Classic Galactosemia (GlobeNewswire)
Mar-13-24 09:23AM	Applied Therapeutics (APLT) Surges 124% in a Month: Here's Why (Zacks)
Mar-08-24 04:32AM	Applied Therapeutics Inc (APLT) Announces Year-End 2023 Financial Results and Clinical Progress (GuruFocus.com)
Mar-06-24 07:00AM	Applied Therapeutics Reports Fourth Quarter and Year-end 2023 Financial Results (GlobeNewswire)
Feb-28-24 01:01PM	FDA Grants Review Date For Applied Therapeutics' First Commercial Product For Rare Metabolic Disorder (Benzinga) +32.62%
09:48AM	Why Is Applied Therapeutics (APLT) Stock Up 59% Today? (InvestorPlace)
08:05AM	Applied Therapeutics Announces $100 Million Private Placement (GlobeNewswire)
08:00AM	Applied Therapeutics Announces FDA Acceptance and Priority Review of New Drug Application for Govorestat for the Treatment of Classic Galactosemia (GlobeNewswire)
Feb-21-24 09:21AM	13 Best Booming Stocks to Buy Right Now (Insider Monkey)
Feb-15-24 07:00AM	Applied Therapeutics Announces Positive Results from 12-month Interim Analysis of Govorestat (AT-007) in the Ongoing INSPIRE Phase 3 Trial in Sorbitol Dehydrogenase (SORD) Deficiency (GlobeNewswire) +39.93%
Jan-05-24 09:23AM	Why Is Applied Therapeutics (APLT) Stock Down 30% Today? (InvestorPlace) -40.63%
03:31AM	Constellation Brands, Costco, Peloton rise premarket; Apple, Tesla fall (Investing.com)
02:32AM	Applied Therapeutics fails heart disease phase 3, seeks partner to bring molecule to market (FierceBiotech.com)
Jan-04-24 04:05PM	Applied Therapeutics Announces Topline Results from the ARISE-HF Phase 3 Study of AT-001 in Diabetic Cardiomyopathy (GlobeNewswire) +5.57%
Jan-03-24 07:00AM	Applied Therapeutics Announces MAA Validation and NDA Submission of Govorestat (AT-007) for Treatment of Classic Galactosemia (GlobeNewswire)
Nov-09-23 08:34AM	Applied Therapeutics Inc (APLT) Reports Q3 2023 Financial Results Amidst Upcoming Clinical ... (GuruFocus.com) -10.39%
07:30AM	Applied Therapeutics Reports Third Quarter 2023 Financial Results (GlobeNewswire)
Nov-02-23 07:00AM	Applied Therapeutics to Present at the UBS Biopharma Conference 2023 (GlobeNewswire)
Nov-01-23 07:00AM	Applied Therapeutics to Host Diabetic Cardiomyopathy Expert Forum with Key Opinion Leaders on Tuesday, November 7 (GlobeNewswire)
Oct-20-23 01:22PM	12 Best Performing Biotech Stocks in 2023 (Insider Monkey)
Sep-28-23 07:00AM	Applied Therapeutics to Present Baseline Data from Phase 3 ARISE-HF Study Evaluating AT-001 at the 2023 EASD Annual Meeting (GlobeNewswire)
Sep-06-23 07:00AM	Applied Therapeutics Announces Successful Pre-NDA Meeting with the FDA and Confirms Plans to Submit NDA for Govorestat (AT-007) for Treatment of Classic Galactosemia to FDA in Q4 2023 (GlobeNewswire) +42.86%
Aug-11-23 07:42AM	We're A Little Worried About Applied Therapeutics' (NASDAQ:APLT) Cash Burn Rate (Simply Wall St.)
Aug-10-23 07:00AM	Applied Therapeutics Reports Second Quarter 2023 Financial Results (GlobeNewswire)
Jul-29-23 11:07AM	10 Stocks That Will Go Up 1000 Percent (Insider Monkey)
Jul-25-23 07:00AM	Applied Therapeutics Provides Regulatory Update on Galactosemia Program (GlobeNewswire) +6.38%
Jun-22-23 07:00AM	Applied Therapeutics to Present Baseline Data on the Phase 3 ARISE-HF Study in Diabetic Cardiomyopathy at the 2023 Annual Meeting of the American Diabetes Association (GlobeNewswire)
Jun-15-23 07:00AM	Applied Therapeutics to Present Data on AT-007 (Govorestat) Treatment in SORD Deficiency at the 2023 Annual Meeting of the Peripheral Nerve Society (GlobeNewswire)
May-25-23 07:00AM	Govorestat (AT-007) Receives Orphan Medicinal Product Designation from the EMA for Treatment of SORD Deficiency (GlobeNewswire)
May-11-23 07:00AM	Applied Therapeutics Reports First Quarter 2023 Financial Results (GlobeNewswire)
May-05-23 02:24PM	7 Hot Growth Stocks Poised to Triple in 2023 (InvestorPlace)
Apr-24-23 07:00AM	Applied Therapeutics, Inc. Announces $30 Million Private Placement of Equity (GlobeNewswire) +16.28%
07:00AM	Applied Therapeutics Announces Clinical Benefit of Govorestat (AT-007) in ACTION-Galactosemia Kids Trial; Company Plans to Meet with FDA Regarding Potential NDA Submission (GlobeNewswire)
Mar-23-23 06:30AM	Applied Therapeutics Reports Fourth Quarter and Year-end 2022 Financial Results (GlobeNewswire) -5.61%
Mar-18-23 09:54AM	Quite a few insiders invested in Applied Therapeutics, Inc. (NASDAQ:APLT) last year which is positive news for shareholders (Simply Wall St.)
Mar-01-23 07:00AM	Applied Therapeutics to Present at the Cowen 43rd Annual Health Care Conference (GlobeNewswire)
Feb-16-23 10:46AM	Applied Therapeutics Reveals Pivotal Study Data In Hereditary Neuropathy (Benzinga) +17.00%
07:00AM	Applied Therapeutics Announces Positive Sorbitol Reduction Data From the Ongoing Phase 3 INSPIRE Trial in Sorbitol Dehydrogenase (SORD) Deficiency (GlobeNewswire)
Feb-09-23 07:00AM	Applied Therapeutics to Present at the SVB Securities Global Biopharma Conference (GlobeNewswire)
Jan-04-23 06:00AM	Applied Therapeutics Announces Partnership with Advanz Pharma for Commercialization of AT-007 (Govorestat) in Europe (GlobeNewswire) +15.28%
Nov-09-22 07:00AM	Applied Therapeutics Reports Third Quarter 2022 Financial Results (GlobeNewswire) -8.62%
Oct-31-22 07:00AM	Applied Therapeutics Announces Multiple Data Presentations at the American Heart Association Scientific Sessions November 5-7, 2022 (GlobeNewswire) +6.73%
Oct-25-22 07:00AM	Applied Therapeutics Announces Full Enrollment in the Registrational Phase 3 ARISE-HF Trial of AT-001 in Diabetic Cardiomyopathy (GlobeNewswire) +6.91%
Oct-09-22 09:13AM	Insiders who purchased Applied Therapeutics, Inc. (NASDAQ:APLT) earlier this year lose an additional US$86k as the stock sinks to US$0.62 (Simply Wall St.)
Oct-06-22 11:18AM	Applied Therapeutics' Lead Candidate Pediatric Study Failed To Reach Statistical Significance (Benzinga) -33.47%
07:00AM	Applied Therapeutics Announces Positive Data Trend in AT-007 ACTION-Galactosemia Kids Pediatric Trial; Trial Will Continue to 18 Months in Blinded Format (GlobeNewswire)
Sep-02-22 09:55AM	Bears are Losing Control Over Applied Therapeutics Inc. (APLT), Here's Why It's a 'Buy' Now (Zacks) -8.45%
Aug-12-22 07:00AM	Applied Therapeutics Reports Second Quarter 2022 Financial Results (GlobeNewswire)
Jul-28-22 07:00AM	Applied Therapeutics to Sponsor and Present at the 2022 Galactosemia Foundation Conference (GlobeNewswire)
Jun-22-22 10:12PM	Applied Therapeutics, Inc. Announces Pricing of $30 Million Public Offering of Common Stock and Warrants (GlobeNewswire) -28.97%
04:10PM	Applied Therapeutics, Inc. Announces Public Offering of Common Stock and Warrants (GlobeNewswire)
Jun-16-22 08:08AM	Companies Like Applied Therapeutics (NASDAQ:APLT) Could Be Quite Risky (Simply Wall St.) -9.49%
Jun-03-22 07:00AM	Applied Therapeutics Receives Orphan Medicinal Product Designation from the EMA for AT-007 for Treatment of Galactosemia (GlobeNewswire)
May-20-22 09:50AM	Dr. Reddy's (RDY) Q4 Earnings Decline Y/Y, Sales Increase (Zacks) -5.26%
May-19-22 07:00AM	Applied Therapeutics to Present at the UBS Global Healthcare Conference (GlobeNewswire)
May-18-22 11:47AM	Ultragenyx (RARE) Acquires Rights of AAV Gene Therapy Candidate (Zacks) -7.65%
11:03AM	Horizon (HZNP) Begins Enrollment in Alopecia Areata Study (Zacks)
May-17-22 11:31AM	Seagen's (SGEN) Stock Up on CEO's Resignation Announcement (Zacks)
May-13-22 10:30AM	Editas' (EDIT) EDIT-301 Gets Orphan Drug Tag for Beta Thalassemia (Zacks)
08:28AM	The Zacks Analyst Blog Highlights Angion Biomedica, Applied Therapeutics, Bolt Biotherapeutics, Ikena Oncology, and Landos Biopharma (Zacks)
May-12-22 06:59AM	Applied Therapeutics Reports First Quarter 2022 Financial Results (GlobeNewswire)
May-11-22 07:32AM	5 Biotech Stocks Set to Outpace Q1 Earnings Estimates (Zacks)
May-05-22 07:30AM	Applied Therapeutics to Present Data on AT-007 Treatment in SORD Deficiency at the 2022 Annual Meeting of the Peripheral Nerve Society (GlobeNewswire) -6.34%
May-03-22 10:47AM	What Awaits Meridian Bioscience (VIVO) This Earnings Season? (Zacks)
May-02-22 07:12AM	Great news for Applied Therapeutics, Inc. (NASDAQ:APLT): Insiders acquired stock in large numbers last year (Simply Wall St.)
Apr-28-22 10:24AM	Zosano (ZSAN) to Report Q1 Earnings: What's in the Cards? (Zacks)
Apr-12-22 11:47AM	Editas (EDIT) Begins Dosing Pediatric Patients in Gene Drug Study (Zacks) -7.76%
Apr-08-22 11:39AM	Aptinyx (APTX) Tanks as Neuropathic Pain Study Misses Goal (Zacks)

Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company which engages in the development of a pipeline of novel products. It is targeting treatments for central nervous system rare diseases and diabetic complications. The company was founded by Shoshana Shendelman on January 20, 2016 and is headquartered in New York, NY.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Funtleyder Leslie D.	Chief Financial Officer	Aug 22 '24	Sale	5.83	13,530	78,880	277,911	Aug 23 04:35 PM
Perfetti Riccardo	Chief Medical Officer	Aug 22 '24	Sale	5.83	22,681	132,230	986,853	Aug 23 04:33 PM
Shendelman Shoshana	President and CEO	Aug 13 '24	Sale	6.18	357,423	2,208,874	4,810,430	Aug 14 07:01 PM
Shendelman Shoshana	President and CEO	Aug 12 '24	Sale	5.98	300,000	1,794,000	5,167,853	Aug 14 07:01 PM
Shendelman Shoshana	President and CEO	Aug 14 '24	Sale	5.93	119,591	709,175	4,690,839	Aug 14 07:01 PM
Shendelman Shoshana	Officer	Aug 12 '24	Proposed Sale	6.21	1,000,000	6,210,000		Aug 09 08:43 PM
Shendelman Shoshana	President and CEO	Jun 06 '24	Sale	4.32	61,795	266,954	3,756,019	Jun 10 04:29 PM
Perfetti Riccardo	Chief Medical Officer	Jun 06 '24	Sale	4.32	22,003	95,053	1,009,534	Jun 10 04:28 PM
Funtleyder Leslie D.	Chief Financial Officer	Jun 06 '24	Sale	4.32	16,980	73,354	291,441	Jun 10 04:25 PM
ALEXANDRIA REAL ESTATE EQUITIE	10% Owner	Jun 05 '24	Sale	4.24	150,000	636,000	5,855,077	Jun 06 06:45 PM
ALEXANDRIA REAL ESTATE EQUITIE	10% Owner	Jun 04 '24	Sale	4.21	150,000	631,500	6,005,077	Jun 06 06:45 PM
Shendelman Shoshana	President and CEO	Mar 14 '24	Sale	5.39	318,573	1,717,108	3,817,814	Mar 18 06:12 PM
Perfetti Riccardo	Chief Medical Officer	Mar 14 '24	Sale	5.39	110,804	597,234	1,031,537	Mar 18 06:02 PM
Hansard Adam	Chief Commercial Officer	Mar 14 '24	Sale	5.39	48,871	263,415	732,919	Mar 18 06:00 PM
Funtleyder Leslie D.	Chief Financial Officer	Mar 14 '24	Sale	5.39	28,727	154,839	308,421	Mar 18 05:57 PM

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APLT

Applied Therapeutics Inc

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