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IONS Ionis Pharmaceuticals, Inc. monthly Stock Chart
IONS [NASD]
Ionis Pharmaceuticals, Inc.
Index- P/E25.29 EPS (ttm)2.56 Insider Own0.20% Shs Outstand145.57M Perf Week-3.98%
Market Cap9.42B Forward P/E216.45 EPS next Y0.30 Insider Trans-62.21% Shs Float127.68M Perf Month-12.37%
Income359.60M PEG0.57 EPS next Q-0.26 Inst Own84.10% Short Float7.99% Perf Quarter4.95%
Sales752.50M P/S12.52 EPS this Y139.20% Inst Trans-0.70% Short Ratio7.37 Perf Half Y21.45%
Book/sh8.71 P/B7.43 EPS next Y219.20% ROA14.40% Target Price69.07 Perf Year46.79%
Cash/sh15.48 P/C4.18 EPS next 5Y44.00% ROE39.30% 52W Range40.91 - 86.58 Perf YTD19.72%
Dividend- P/FCF13.80 EPS past 5Y41.70% ROI13.60% 52W High-25.25% Beta2.30
Dividend %- Quick Ratio9.40 Sales past 5Y32.40% Gross Margin55.00% 52W Low58.20% ATR2.98
Employees737 Current Ratio9.40 Sales Q/Q105.80% Oper. Margin8.40% RSI (14)35.18 Volatility4.07% 3.89%
OptionableYes Debt/Eq0.55 EPS Q/Q- Profit Margin47.80% Rel Volume1.87 Prev Close67.14
ShortableYes LT Debt/Eq0.54 EarningsMay 09 BMO Payout0.00% Avg Volume1.38M Price64.72
Recom2.90 SMA20-7.26% SMA50-14.71% SMA2009.37% Volume2,588,017 Change-3.60%
Aug-08-18Reiterated Stifel Hold $48 → $47
Aug-07-18Reiterated Stifel Hold $55 → $48
May-08-18Downgrade Evercore ISI Outperform → In-line
Oct-06-17Resumed Goldman Sell $30
Aug-17-17Initiated Evercore ISI Outperform $65
Aug-09-17Reiterated Stifel Hold $42 → $50
Mar-10-17Downgrade Goldman Neutral → Sell
Dec-28-16Reiterated BMO Capital Markets Outperform $61 → $68
Dec-27-16Reiterated Leerink Partners Mkt Perform $40 → $47
Dec-27-16Reiterated Laidlaw Buy $59 → $65
Nov-10-16Resumed Leerink Partners Mkt Perform
Aug-10-16Reiterated Piper Jaffray Overweight $36 → $46
Aug-03-16Initiated Morgan Stanley Equal-Weight $37
Aug-02-16Reiterated Needham Buy $55 → $64
Aug-02-16Reiterated Barclays Equal Weight $26 → $41
May-27-16Reiterated Needham Buy $88 → $55
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May-20-19 09:35PM  Edited Transcript of IONS earnings conference call or presentation 9-May-19 3:30pm GMT Thomson Reuters StreetEvents
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04:11PM  Highly-Rated Biotech Post 106% Sales Growth In Profitable First Quarter Investor's Business Daily
08:45AM  Ionis Pharmaceuticals (IONS) Beats Q1 Earnings and Revenue Estimates Zacks
07:36AM  Ionis Pharmaceuticals: 1Q Earnings Snapshot Associated Press
07:00AM  Ionis reports first quarter 2019 financial results PR Newswire
May-08-19 04:05PM  Akcea Reports Financial Results and Highlights for First Quarter 2019 GlobeNewswire
10:38AM  Drug/Biotech Stock Q1 Earnings on May 9: IONS, XLRN & More Zacks
May-07-19 04:05PM  New Long-Term TEGSEDI Safety and Efficacy Data Featured as an Oral Presentation at 2019 American Academy of Neurology Annual Meeting (AAN) GlobeNewswire -7.04%
08:41AM  Akcea and Ionis Announce Approval of WAYLIVRA® (volanesorsen) in the European Union GlobeNewswire
May-06-19 04:14PM  How Dow Jones' Pfizer Could Take On New Drugs From 2 Biotech Stocks Investor's Business Daily
07:05AM  Ionis launches new corporate brand that reflects company's industry-leading innovation and unique culture of saying "yes" to patients PR Newswire
May-02-19 10:33AM  Ionis Pharmaceuticals (IONS) Earnings Expected to Grow: What to Know Ahead of Next Week's Release Zacks
07:05AM  Akcea Announces Upcoming Data Presentations at the 2019 American Academy of Neurology Meeting (AAN.19) GlobeNewswire
May-01-19 09:15AM  S&P Ends a Strong April with 3rd Straight Record Close Zacks
07:05AM  Positive clinical data at AAN 2019 reinforces Ionis' commitment to delivering life-changing medicines to patients with neurological diseases PR Newswire
Apr-28-19 11:19AM  Biogen says it will not give up on Alzheimers after failed trials MarketWatch
Apr-26-19 10:30AM  Ionis Pharmaceuticals (IONS) Earnings Expected to Grow: What to Know Ahead of Q1 Release Zacks
Apr-25-19 03:47PM  Biogen Looks to 23 Clinical Programs for Growth Motley Fool
07:05AM  Ionis Pharmaceuticals to hold first quarter 2019 financial results webcast PR Newswire
Apr-24-19 09:15AM  Solid Earnings Boost S&P, NASDAQ to New Closing Highs Zacks
07:00AM  Akcea Therapeutics to Hold First Quarter 2019 Financial Results Webcast GlobeNewswire
Apr-23-19 08:58AM  Is Ionis Pharmaceuticals, Inc.'s (NASDAQ:IONS) Balance Sheet Strong Enough To Weather A Storm? Simply Wall St.
Apr-22-19 10:57AM  The Zacks Analyst Blog Highlights: Alteryx, CommScope, Ionis Pharmaceuticals and Apache Zacks
Apr-18-19 08:09PM  Hedge Funds Dropped The Ball On Ionis Pharmaceuticals, Inc. (IONS)? Insider Monkey
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Apr-17-19 04:52PM  Why A Highly Rated Biotech With A 54% Gain This Year Is Being Gutted Investor's Business Daily -12.74%
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09:15AM  NASDAQ Back Above 8,000 Zacks
Apr-11-19 08:00AM  5 Stocks to Sell as They Climb to New Highs InvestorPlace
Apr-10-19 09:15AM  S&P Streak Ends as Stocks Step Back Zacks
Apr-08-19 04:05PM  Ionis Pharmaceuticals to Provide Corporate Update at 2019 Annual Meeting of Stockholders PR Newswire
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Mar-27-19 09:15AM  S&P Fights Past Growth Concerns to Reclaim 2800 Zacks
Mar-25-19 07:05AM  Ionis announces appointment of Brett P. Monia Ph.D. to its board of directors PR Newswire
Mar-15-19 04:05PM  Akcea and Ionis Announce Upcoming Data Presentations at the 2019 American College of Cardiology Meeting (ACC.19) GlobeNewswire
Mar-08-19 04:39PM  IBD Stock Of The Day Obliterates Earnings Views And Eyes New Buy Point Investor's Business Daily
12:27PM  6 of the Most Expensive Stocks That Could Go On Sale InvestorPlace
Mar-07-19 07:05AM  Ionis Pharmaceuticals to Present at Upcoming Investor Conferences PR Newswire
Mar-05-19 12:22AM  Edited Transcript of IONS earnings conference call or presentation 27-Feb-19 4:30pm GMT Thomson Reuters StreetEvents
Mar-04-19 03:46PM  Ionis Pharmaceuticals Funds Its Pipeline of More Than 40 Drugs Motley Fool
12:00AM  Detailed Research: Economic Perspectives on Huntsman, eHealth, Ionis Pharmaceuticals, Arch Capital Group, Copart, and Acorda Therapeutics What Drives Growth in Today's Competitive Landscape GlobeNewswire
Mar-01-19 03:48PM  Ionis Pharmaceuticals Inc (IONS) Files 10-K for the Fiscal Year Ended on December 31, 2018 GuruFocus.com
08:44AM  EU committee approves Akcea-Ionis drug for rare genetic disease Reuters
07:45AM  Akcea and Ionis Receive Positive EU CHMP Opinion for WAYLIVRATM (volanesorsen) GlobeNewswire
Feb-27-19 07:52PM  Ionis Pharmaceuticals (IONS) Q4 2018 Earnings Conference Call Transcript Motley Fool +15.12%
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Feb-20-19 10:31AM  Analysts Estimate Ionis Pharmaceuticals (IONS) to Report a Decline in Earnings: What to Look Out for Zacks
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06:00AM  Top Picks 2019- Ionis Pharmaceuticals IONS MoneyShow
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Dec-21-18 04:26PM  Why Gene Therapy Is More Cost Effective Than Biogen's Approved Drug Investor's Business Daily
Dec-20-18 06:39PM  Ionis Pharmaceuticals outlines CEO succession plan MarketWatch
05:41PM  Ionis Announces Plans for Management Transitions in 2020 PR Newswire
07:20AM  New Research: Key Drivers of Growth for Baxter International, Sempra Energy, Nielsen Holdings Plc, ARRIS International plc, Ionis Pharmaceuticals, and KB Home Factors of Influence, Major Initiatives and Sustained Production GlobeNewswire
Dec-14-18 12:47AM  Should You Buy Ionis Pharmaceuticals, Inc. (IONS)? Insider Monkey
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Dec-12-18 10:03AM  Biotech Stock Roundup: Gilead to Get New CEO, Biogen In-Licenses Candidate Zacks
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Dec-06-18 07:30AM  Biogen Exercises Option with Ionis to Develop and Commercialize Investigational Treatment BIIB067 for a Subtype of Familial Amyotrophic Lateral Sclerosis (ALS) Based on Positive Phase 1 Data GlobeNewswire
Nov-29-18 05:30PM  Why Pfizer Could Lead These Two Biotech Stocks In Tackling Amyloidosis Investor's Business Daily
07:30AM  International Prix Galien Recognizes SPINRAZA® as Best Biotechnology Product GlobeNewswire
Nov-27-18 07:00AM  First-in-class therapies using advanced antisense chemistries highlighted at 2018 American Society of Hematology Annual Meeting PR Newswire
Nov-19-18 05:00AM  Edited Transcript of IONS earnings conference call or presentation 6-Nov-18 4:30pm GMT Thomson Reuters StreetEvents
Nov-14-18 09:15AM  Stocks Not in a Bouncy Mood Yet Zacks
Nov-13-18 07:07AM  Ionis Pharmaceuticals to Present at Jefferies 2018 London Healthcare Conference PR Newswire
Nov-12-18 03:16PM  5 Pharma Stocks to Stay Away From InvestorPlace
12:50PM  Ionis Pharmaceuticals Collects Royalties -- and Spends It All Motley Fool
06:55AM  Phase 2 Results on AKCEA-APO(a)-LRx Presented in Late-Breaking Clinical Trial Presentation at AHA Scientific Sessions GlobeNewswire
Nov-09-18 07:07AM  Ionis Pharmaceuticals to Host Investor Day PR Newswire
Nov-08-18 09:00AM  Recent Analysis Shows Automatic Data Processing, GTx, Ionis Pharmaceuticals, TriNet Group, Ternium S.A, and UNIVERSAL INSURANCE HOLDINGS INC Market Influences Renewed Outlook, Key Drivers of Growth GlobeNewswire
07:00AM  Akcea and Ionis Announce Late-Breaking Presentation of Data From AKCEA-APO(a)-LRx at the American Heart Association Scientific Sessions GlobeNewswire
Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; and TEGSEDI, an injection for the treatment of polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults. It is involved in developing neurology products that include IONIS-HTTRx for Huntington's diseases; and IONIS-SOD1Rx and IONIS-C9Rx for amyotrophic lateral sclerosis and IONIS-MAPTRx for Alzheimer's diseases. The company is also developing severe and rare disease products, such as WAYLIVRA, a treatment for familial chylomicronemia syndrome; WAYLIVRA, a treatment for familial partial lipodystrophy; AKCEA-TTR-LRx for transthyretin amyloidosis and IONIS-GHR-LRx for acromegaly; and IONIS-TMPRSS6-LRx for beta-thalassemia and iron toxicity, IONIS-PKKRx/IONIS-PKK-LRx for hereditary angioedema, and IONIS-ENAC-2.5Rx for cystic fibrosis. In addition, its cardio metabolic and renal drugs include AKCEA-ANGPTL3-LRx for cardio metabolic disorders, IONIS-FXIRx for clotting disorders, AKCEA-APO(a)-LRx and AKCEA-APOCIII-LRx for cardiovascular diseases, and IONIS-DGAT2Rx for nonalcoholic steatohepatitis; IONIS-AGT-LRX for the treatment of resistant hyper tension; and IONIS-FXI-LRx for clotting disorders and IONIS-AZ4-2.5-LRx for cardiovascular diseases. Further, the company develops products for oncology that include IONIS-AR-2.5Rx and danvatirsen for cancers; and IONIS-HBVRx and IONIS-HBV-LRx for hepatitis b virus infection, and IONIS-FB-LRx for compliment meditated disease, and IONIS-JBI1-2.5Rx for gastrointestinal autoimmune diseases. Ionis Pharmaceuticals, Inc. was founded in 1989 and is based in Carlsbad, California.
Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total SEC Form 4
MUTO FREDERICK TDirectorMay 06Option Exercise24.428,000195,36017,794May 08 06:16 PM
MUTO FREDERICK TDirectorMay 06Sale72.758,000582,0029,794May 08 06:16 PM
PARSHALL B LYNNEDirectorApr 29Option Exercise39.8750,0001,993,500102,677May 01 05:48 PM
PARSHALL B LYNNEDirectorApr 29Sale75.0150,0003,750,63552,677May 01 05:48 PM
CROOKE STANLEY TChairman and CEOApr 16Option Exercise31.161,00031,1556,232Apr 17 07:30 PM
CROOKE STANLEY TChairman and CEOApr 16Option Exercise31.4620,000629,19882,954Apr 17 07:30 PM
CROOKE STANLEY TChairman and CEOApr 16Sale84.751,00084,7505,532Apr 17 07:30 PM
CROOKE STANLEY TChairman and CEOApr 16Sale84.6220,0001,692,50069,634Apr 17 07:30 PM
CROOKE STANLEY TChairman and CEOApr 15Option Exercise10.821,00010,8206,532Apr 17 07:30 PM
CROOKE STANLEY TChairman and CEOApr 15Option Exercise14.6910,000146,90079,634Apr 17 07:30 PM
CROOKE STANLEY TChairman and CEOApr 15Sale85.251,00085,2505,532Apr 17 07:30 PM
CROOKE STANLEY TChairman and CEOApr 15Sale85.2510,000852,50069,634Apr 17 07:30 PM
Geary Richard SSVP, DevelopmentApr 08Option Exercise42.5346,2401,966,46645,442Apr 10 06:24 PM
Geary Richard SSVP, DevelopmentApr 08Sale84.0146,2403,884,75321,442Apr 10 06:24 PM
O'NEIL PATRICK R.SVP Legal & General CounselApr 05Option Exercise61.682,252138,90318,925Apr 05 07:29 PM
O'NEIL PATRICK R.SVP Legal & General CounselApr 05Sale84.752,252190,85716,673Apr 05 07:29 PM
O'NEIL PATRICK R.SVP Legal & General CounselApr 04Option Exercise56.7636,6222,078,80935,165Apr 05 07:29 PM
O'NEIL PATRICK R.SVP Legal & General CounselApr 04Sale83.7939,6223,319,92916,673Apr 05 07:29 PM
O'NEIL PATRICK R.SVP Legal & General CounselApr 03Option Exercise61.687,654472,09927,327Apr 05 07:29 PM
O'NEIL PATRICK R.SVP Legal & General CounselApr 03Sale84.837,654649,28919,673Apr 05 07:29 PM
WENDER JOSEPH HDirectorMar 19Sale79.6310,000796,25858,916Mar 20 06:05 PM
O'NEIL PATRICK R.SVP Legal & General CounselMar 18Option Exercise61.5728,8001,773,21648,473Mar 20 06:15 PM
O'NEIL PATRICK R.SVP Legal & General CounselMar 18Sale78.7928,8002,269,18719,673Mar 20 06:15 PM
PARSHALL B LYNNEDirectorMar 12Option Exercise39.878,334332,27761,011Mar 14 06:24 PM
PARSHALL B LYNNEDirectorMar 12Sale75.008,334625,05052,677Mar 14 06:24 PM
O'NEIL PATRICK R.SVP Legal & General CounselFeb 27Option Exercise45.1126,8001,208,95233,773Mar 01 05:40 PM
PARSHALL B LYNNEDirectorFeb 27Option Exercise39.878,333332,23761,010Mar 01 05:56 PM
O'NEIL PATRICK R.SVP Legal & General CounselFeb 27Sale68.0126,8001,822,58019,673Mar 01 05:40 PM
PARSHALL B LYNNEDirectorFeb 27Sale70.008,333583,31052,677Mar 01 05:56 PM
CROOKE STANLEY TChairman and CEOFeb 26Option Exercise39.8737,0001,475,190106,634Feb 27 07:31 PM
CROOKE STANLEY TChairman and CEOFeb 26Sale61.5437,0002,276,79969,634Feb 27 07:31 PM
CROOKE STANLEY TChairman and CEOFeb 25Option Exercise39.8740,0001,594,800109,634Feb 27 07:31 PM
CROOKE STANLEY TChairman and CEOFeb 25Sale60.0740,0002,402,70069,634Feb 27 07:31 PM
CROOKE STANLEY TChairman and CEOFeb 13Option Exercise33.126,904228,66610,832Feb 14 05:57 PM
CROOKE STANLEY TChairman and CEOFeb 13Option Exercise39.8740,0001,594,800109,634Feb 14 05:57 PM
CROOKE STANLEY TChairman and CEOFeb 13Sale60.006,904414,2405,532Feb 14 05:57 PM
CROOKE STANLEY TChairman and CEOFeb 13Sale60.1040,0002,404,02869,634Feb 14 05:57 PM
Geary Richard SSVP, DevelopmentFeb 13Sale60.0099959,94021,442Feb 14 05:51 PM
O'NEIL PATRICK R.SVP Legal & General CounselFeb 12Option Exercise39.8727510,96419,948Feb 14 06:01 PM
O'NEIL PATRICK R.SVP Legal & General CounselFeb 12Sale59.5027516,36319,673Feb 14 06:01 PM
O'NEIL PATRICK R.SVP Legal & General CounselFeb 05Option Exercise39.8715,600621,97235,273Feb 05 06:05 PM
O'NEIL PATRICK R.SVP Legal & General CounselFeb 05Sale59.5015,600928,20019,673Feb 05 06:05 PM
BENNETT C FRANKSVP, Antisense ResearchFeb 01Option Exercise14.699,013132,40133,541Feb 05 05:59 PM
O'NEIL PATRICK R.SVP Legal & General CounselFeb 01Option Exercise39.874,000159,48023,673Feb 05 06:05 PM
BENNETT C FRANKSVP, Antisense ResearchFeb 01Sale58.299,013525,36824,528Feb 05 05:59 PM
O'NEIL PATRICK R.SVP Legal & General CounselFeb 01Sale58.294,000233,16019,673Feb 05 06:05 PM
BENNETT C FRANKSVP, Antisense ResearchJan 15Option Exercise0.007,822027,218Jan 17 07:39 PM
Geary Richard SSVP, DevelopmentJan 15Option Exercise0.008,085024,942Jan 17 07:36 PM
HOUGEN ELIZABETH LSVP Finance & CFOJan 15Option Exercise0.007,891022,665Jan 17 07:35 PM
Monia Brett PChief Operating OfficerJan 15Option Exercise0.0010,006025,847Jan 17 07:34 PM
CROOKE STANLEY TChairman and CEOJan 15Option Exercise0.002,34606,474Jan 17 07:27 PM
CROOKE STANLEY TChairman and CEOJan 15Option Exercise0.0030,587082,320Jan 17 07:27 PM
O'NEIL PATRICK R.SVP Legal & General CounselJan 15Option Exercise0.007,823022,341Jan 17 07:24 PM
PARSHALL B LYNNEDirectorJan 15Option Exercise0.0020,656058,836Jan 17 07:19 PM
O'NEIL PATRICK R.SVP Legal & General CounselJan 03Option Exercise37.234,400163,80818,584Jan 03 07:50 PM
O'NEIL PATRICK R.SVP Legal & General CounselJan 03Sale54.804,400241,12014,584Jan 03 07:50 PM
Monia Brett PChief Operating OfficerJan 02Sale53.5021411,44915,837Jan 03 07:42 PM
HOUGEN ELIZABETH LSVP, Finance & CFODec 19Option Exercise7.252,06314,95716,837Dec 20 05:55 PM
HOUGEN ELIZABETH LSVP, Finance & CFODec 19Sale52.052,063107,37914,774Dec 20 05:55 PM
HOUGEN ELIZABETH LSVP, Finance & CFODec 18Option Exercise7.252,00014,50016,774Dec 20 05:55 PM
HOUGEN ELIZABETH LSVP, Finance & CFODec 18Sale52.002,000104,00014,774Dec 20 05:55 PM
Monia Brett PChief Operating OfficerNov 23Option Exercise14.6934,000499,46049,841Nov 26 08:01 PM
Monia Brett PChief Operating OfficerNov 23Sale55.0034,0001,870,05815,841Nov 26 08:01 PM
BENNETT C FRANKSVP, Antisense ResearchNov 01Option Exercise14.6912,500183,62531,896Nov 01 07:34 PM
BENNETT C FRANKSVP, Antisense ResearchNov 01Sale49.5412,500619,24519,396Nov 01 07:34 PM
Monia Brett PChief Operating OfficerAug 27Option Exercise7.2316,493119,27424,834Aug 29 04:49 PM
Monia Brett PChief Operating OfficerAug 27Sale54.0016,493890,62215,841Aug 29 04:49 PM
BENNETT C FRANKSVP, Antisense ResearchAug 08Option Exercise14.6812,500183,52831,883Aug 09 06:34 PM
BENNETT C FRANKSVP, Antisense ResearchAug 08Sale45.0012,500562,50019,396Aug 09 06:34 PM
Monia Brett PChief Operating OfficerJul 24Sale47.031567,33715,841Jul 25 07:19 PM
WENDER JOSEPH HDirectorJul 17Option Exercise9.2630,000277,80068,916Jul 19 06:45 PM
KLEIN JOSEPH IIIDirectorJul 03Option Exercise0.00667012,606Jul 03 03:07 PM
BERTHELSEN SPENCER RDirectorJul 03Option Exercise0.00667094,094Jul 03 03:08 PM
WENDER JOSEPH HDirectorJul 03Option Exercise0.00667038,916Jul 03 03:10 PM
Castleman BreauxDirectorJul 03Option Exercise0.00667012,294Jul 03 03:13 PM
LOSCALZO JOSEPHDirectorJul 03Option Exercise0.00667010,419Jul 03 03:20 PM
LOSCALZO JOSEPHDirectorJul 01Option Exercise0.002,00009,752Jul 03 03:20 PM
Castleman BreauxDirectorJul 01Option Exercise0.002,000011,627Jul 03 03:13 PM
WENDER JOSEPH HDirectorJul 01Option Exercise0.002,000038,249Jul 03 03:10 PM
BERTHELSEN SPENCER RDirectorJul 01Option Exercise0.002,000093,427Jul 03 03:08 PM
KLEIN JOSEPH IIIDirectorJul 01Option Exercise0.002,000011,939Jul 03 03:07 PM
BERTHELSEN SPENCER RDirectorJun 25Option Exercise13.8815,000208,200100,727Jun 25 08:28 PM
BERTHELSEN SPENCER RDirectorJun 25Sale42.3015,000634,54291,427Jun 25 08:28 PM
MUTO FREDERICK TDirectorMay 31Option Exercise13.8815,000208,20022,127May 31 08:02 PM
MUTO FREDERICK TDirectorMay 31Sale46.4515,000696,7507,127May 31 08:02 PM