KOD Kodiak Sciences Inc. Stock Quote

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KOD [NASD]

Kodiak Sciences Inc.

Healthcare | Biotechnology | USA

statements

Index	-	P/E	-	EPS (ttm)	-2.32	Insider Own	0.10%	Shs Outstand	45.12M	Perf Week	-2.12%
Market Cap	6.60B	Forward P/E	-	EPS next Y	-4.45	Insider Trans	-	Shs Float	41.71M	Perf Month	40.83%
Income	-102.10M	PEG	-	EPS next Q	-0.86	Inst Own	74.50%	Short Float	8.07%	Perf Quarter	164.03%
Sales	-	P/S	-	EPS this Y	-11.40%	Inst Trans	-3.62%	Short Ratio	8.40	Perf Half Y	110.21%
Book/sh	6.25	P/B	21.60	EPS next Y	-63.00%	ROA	-23.90%	Target Price	105.06	Perf Year	395.05%
Cash/sh	7.78	P/C	17.36	EPS next 5Y	12.40%	ROE	-32.30%	52W Range	25.84 - 141.98	Perf YTD	87.63%
Dividend	-	P/FCF	-	EPS past 5Y	-	ROI	-	52W High	-4.92%	Beta	-
Dividend %	-	Quick Ratio	17.00	Sales past 5Y	-	Gross Margin	-	52W Low	422.53%	ATR	10.96
Employees	62	Current Ratio	17.00	Sales Q/Q	-	Oper. Margin	-	RSI (14)	68.38	Volatility	9.32% 9.88%
Optionable	Yes	Debt/Eq	0.00	EPS Q/Q	-141.40%	Profit Margin	-	Rel Volume	0.44	Prev Close	132.20
Shortable	Yes	LT Debt/Eq	0.00	Earnings	-	Payout	-	Avg Volume	400.57K	Price	135.00
Recom	2.20	SMA20	17.52%	SMA50	53.68%	SMA200	117.46%	Volume	175,247	Change	2.12%

Nov-30-20

Downgrade

JP Morgan

Overweight → Neutral

$74 → $125

Nov-16-20

Downgrade

Morgan Stanley

Overweight → Equal-Weight

$80 → $125

Nov-13-20

Downgrade

Goldman

Buy → Neutral

$83 → $105

Mar-31-20

Initiated

BMO Capital Markets

Outperform

$74

Mar-03-20

Initiated

Goldman

Buy

$80

Feb-18-20

Downgrade

Barclays

Overweight → Equal Weight

$69

Feb-06-20

Initiated

SunTrust

Buy

Jan-08-20

Initiated

ROTH Capital

Buy

$115

Jan-03-20

Initiated

Jefferies

Buy

$100

Dec-24-19

Initiated

JP Morgan

Overweight

$82

Oct-15-19

Reiterated

Chardan Capital Markets

Buy

$22.50 → $35

Feb-20-19

Initiated

Chardan Capital Markets

Buy

$22.50

Oct-29-18

Initiated

Morgan Stanley

Overweight

$20

Oct-29-18

Initiated

BofA/Merrill

Buy

$14

Oct-29-18

Initiated

Barclays

Overweight

$20

Nov-27-20 03:02PM	Kodiak Sciences, Playa Hotel See Activist Action Barrons.com
Nov-20-20 04:03PM	Kodiak Sciences Announces Closing of $645.0 Million Public Offering of Common Stock and Full Exercise of Underwriters' Option to Purchase Additional Shares PR Newswire
Nov-17-20 09:02PM	Kodiak Sciences Announces Pricing of $560.9 Million Public Offering of Common Stock PR Newswire
01:16PM	Kodiak (KOD) Closes Enrollment in Phase IIb/III Wet AMD Study Zacks
Nov-16-20 04:01PM	Kodiak Sciences Announces Proposed Offering of Common Stock PR Newswire
06:53AM	Kodiak Sciences Completes Enrollment of DAZZLE Phase 2b/3 Pivotal Study of KSI-301 in Patients with Wet Age-Related Macular Degeneration PR Newswire
Nov-12-20 04:12PM	Kodiak Sciences to Present at Upcoming Conferences PR Newswire
Nov-11-20 11:27PM	Kodiak Sciences Announces Presentation of KSI-301 Phase 1b Clinical Study Data Focused on Diabetic Macular Edema at American Academy of Ophthalmology (AAO) 2020 Virtual Meeting PR Newswire
Nov-10-20 11:44AM	Kodiak Sciences (KOD) Q3 Earnings Miss, KSI-301 in Focus Zacks
Nov-09-20 05:30AM	Kodiak Sciences Announces Third Quarter 2020 Financial Results and Recent Business Highlights PR Newswire
Oct-26-20 07:53AM	2 Top Healthcare Stocks That Jumped Last Week Motley Fool
Oct-12-20 04:56PM	Hedge Funds Are Getting Bullish On Kodiak Sciences Inc (KOD) Insider Monkey
Oct-05-20 09:02AM	Kodiak Sciences Treats First Patients in Three Phase 3 Studies of KSI-301 - Two Studies in Diabetic Macular Edema and One Study in Macular Edema Due to Retinal Vein Occlusion PR Newswire
Sep-02-20 04:08PM	Kodiak Sciences to Present at Upcoming Conferences PR Newswire
Aug-10-20 05:30AM	Kodiak Sciences Announces Second Quarter 2020 Financial Results and Recent Business Highlights PR Newswire
Jul-31-20 06:00AM	How Bill Gates would treat COVID-19 if he were President of the United States Yahoo Finance Video
Jul-16-20 04:38PM	Kodiak Sciences to Host R&D Webcast to Review Recent Data from the Ongoing Phase 1b Study of KSI-301 and Highlight KSI-301 Clinical Development Progress PR Newswire -6.66%
Jul-10-20 04:00PM	Kodiak Sciences Announces New Longer-Term Safety, Efficacy and Durability Data from Ongoing Phase 1b Study of KSI-301 in Patients with Wet Age-Related Macular Degeneration, Diabetic Macular Edema and Retinal Vein Occlusion at the American Society of Retina Specialists (ASRS) 2020 Virtual Annual Meeting PR Newswire
Jul-07-20 08:38AM	Kodiak Sciences Announces Upcoming Presentation of KSI-301 Clinical Study Data at American Society of Retina Specialists (ASRS) 2020 Virtual Annual Meeting and R&D Webinar PR Newswire
Jul-05-20 03:30PM	Hedge Funds Keep Buying Kodiak Sciences Inc (KOD) Insider Monkey
Jun-12-20 10:20PM	Why Kodiak Sciences (KOD) Stock Might be a Great Pick Zacks
Jun-05-20 12:00PM	Kodiak Sciences Inc. (KOD) Upgraded to Buy: What Does It Mean for the Stock? Zacks -7.40%
May-29-20 01:38PM	Top Small Cap Stocks for June 2020 Investopedia
May-28-20 08:22AM	Kodiak Sciences to Present at Upcoming Conferences PR Newswire
May-26-20 11:02AM	Kodiak Sciences' Shares March Higher, Can It Continue? Zacks
May-13-20 07:01AM	Kodiak Sciences Inc. (KOD) Q1 2020 Earnings Call Transcript Motley Fool
May-11-20 04:13PM	Kodiak Sciences to Present at the Bank of America Merrill Lynch Health Care Conference PR Newswire
05:30AM	Kodiak Sciences Announces First Quarter 2020 Financial Results and Recent Business Highlights PR Newswire
May-08-20 04:30PM	Kodiak Sciences to Host First Quarter 2020 Business Highlights Webcast on May 12, 2020 PR Newswire
Apr-07-20 11:35AM	Hedge Funds Have Never Been This Bullish On Kodiak Sciences Inc (KOD) Insider Monkey -8.25%
Apr-02-20 04:08PM	Kodiak Sciences Appoints Charles Bancroft to Board of Directors PR Newswire
Mar-24-20 04:23PM	Biotech stocks have held up better than the broader market and these five are potential winners MarketWatch
08:51AM	"Kodiak" and "Kodiak Sciences" Trademarks Registered to Kodiak Sciences Inc. for Its Exclusive Use PR Newswire
Mar-23-20 01:37PM	Laurent Condon Triumphs Again, Wins My 3-Stock Derby GuruFocus.com
Mar-18-20 02:29PM	Top Biotech Stocks for Q2 2020 Investopedia -8.13%
Mar-16-20 05:30AM	Kodiak Sciences Announces Fourth Quarter and Full Year 2019 Financial Results and Recent Business Highlights PR Newswire -24.16%
Mar-03-20 12:08PM	3 Reasons Goldman Sachs Is Bullish On Kodiak Sciences Benzinga
Feb-27-20 06:00AM	Kodiak Sciences to Present at Upcoming Conferences PR Newswire -7.69%
Feb-21-20 03:14PM	3 micro-cap names that may capture unicorn-like growth: Analyst Yahoo Finance
Feb-08-20 03:30PM	Kodiak Sciences Announces Additional Safety, Efficacy and Durability Data from Ongoing Phase 1b Study of KSI-301 in Patients with Wet Age-Related Macular Degeneration, Diabetic Macular Edema and Retinal Vein Occlusion at the Angiogenesis, Exudation, and Degeneration 2020 Meeting PR Newswire
Jan-14-20 03:56PM	These 3 Momentum Stocks Have Room for Further Upside, Says Jefferies TipRanks
Jan-08-20 06:00AM	Kodiak Sciences to Present at 38th Annual J.P. Morgan Healthcare Conference PR Newswire
Dec-27-19 02:19PM	Biotech Rally Sends Nasdaq to 9000: ETFs in Focus Zacks
Dec-26-19 07:55AM	The Daily Biotech Pulse: Qiagen Opts To Stay Solo Following Strategic Review, Spectrum Slumps On Negative Data, Microbot Medical To Offer Shares Benzinga
Dec-25-19 11:30AM	Is Kodiak Sciences (KOD) Stock Outpacing Its Medical Peers This Year? Zacks
Dec-24-19 12:00PM	Kodiak Sciences Inc. (KOD) is a Great Momentum Stock: Should You Buy? Zacks +15.96%
Dec-22-19 01:21PM	Did Hedge Funds Drop The Ball On Kodiak Sciences Inc (KOD) ? Insider Monkey
Dec-20-19 07:30AM	Will Kodiak Sciences Continue to Surge Higher? Zacks
Dec-19-19 04:01PM	Kodiak Sciences Appoints Taiyin Yang, Ph.D., to Board of Directors PR Newswire
12:20PM	Surging Earnings Estimates Signal Upside for Kodiak Sciences Inc. (KOD) Stock Zacks
Dec-14-19 07:30AM	Surging Biotech Stocks Kodiak Sciences, Immunomedics See Largest Holders Buy More Barrons.com
Dec-06-19 04:15PM	Kodiak Sciences Announces Closing of $317.4 Million Public Offering of Common Stock and Full Exercise of Underwriters' Option to Purchase Additional Shares PR Newswire
Dec-03-19 09:07PM	Kodiak Sciences Announces Pricing of $276.0 Million Public Offering of Common Stock PR Newswire
08:41AM	Benzinga Pro's Top 6 Stocks To Watch For Tues., Dec. 3, 2019: CARA, VRAY, LE, KOD, FXI, ROKU Benzinga
07:59AM	The Daily Biotech Pulse: Astellas To Buy Audentes For $3B, Applied Genetics Chief Medical Officer Quits, Axsome Aces Midstage Trial Benzinga
Dec-02-19 05:00PM	Kodiak Sciences Announces Proposed Offering of Common Stock PR Newswire +72.47%
09:51AM	Longtime biotech investor injects $250M into Palo Alto company a year after IPO American City Business Journals
07:00AM	Kodiak Sciences to Present at the Evercore ISI HealthCONx Conference PR Newswire
06:00AM	Kodiak Sciences Announces Sale of Future Royalties on KSI-301 for $225 Million to Baker Bros. Advisors PR Newswire
Nov-27-19 12:15PM	5 Stocks That Pushed Russell 2000 ETF Higher Zacks
Nov-12-19 07:20AM	The Daily Biotech Pulse: Reata, Kadmon Clinical Readouts, Apyx Medical's Earnings Beat Benzinga -6.10%
05:30AM	Kodiak Sciences Announces Third Quarter 2019 Financial Results and Recent Business Highlights PR Newswire
Nov-08-19 07:00AM	Kodiak Sciences to Report Third Quarter 2019 Results and Host Business Highlights Webcast on November 12, 2019 PR Newswire
Oct-11-19 07:58PM	Kodiak Sciences Announces Safety, Efficacy and Durability Data from Ongoing Phase 1b Study of KSI-301 in Patients with Wet Age-Related Macular Degeneration, Diabetic Macular Edema and Retinal Vein Occlusion at the American Academy of Ophthalmology Annual Meeting Retina Subspecialty Day PR Newswire +7.63%
06:00AM	Kodiak Sciences to Host R&D Day on October 14 in San Francisco to Highlight Recent Clinical Progress and Development Planning for KSI-301 PR Newswire
Oct-10-19 07:39PM	Kodiak Sciences Treats First Patients in DAZZLE Pivotal Study of KSI-301 in Wet Age-Related Macular Degeneration PR Newswire +9.03%
Oct-07-19 06:00AM	Kodiak Sciences Announces Upcoming Presentation of Durability Data from Clinical Development Program of KSI-301 in Wet AMD, DME, and RVO at American Academy of Ophthalmology 2019 Annual Meeting PR Newswire
Oct-04-19 02:27PM	Disappointed by WeWork? Check Out These IPO Stocks. InvestorPlace
Sep-15-19 06:08AM	Kodiak Sciences Announces Emerging Durability Data from Ongoing Phase 1b Study of KSI-301 in Wet AMD Patients at The Retina Society Annual Meeting PR Newswire
Sep-12-19 06:00AM	Kodiak Sciences to Release Durability Data from Clinical Development Program of KSI-301 for wet AMD at The Retina Society Annual Meeting PR Newswire
Sep-06-19 06:00AM	Kodiak Sciences to Present at the Morgan Stanley Global Healthcare Conference PR Newswire
Sep-04-19 06:30PM	Kodiak Sciences Announces Upcoming Presentations at EURETINA Meeting PR Newswire
Aug-23-19 11:36AM	Kodiak Sciences Inc. (NASDAQ:KOD) Insiders Increased Their Holdings Simply Wall St.
Aug-14-19 05:30AM	Kodiak Sciences Announces Second Quarter 2019 Financial Results and Recent Business Highlights PR Newswire -9.93%
Aug-08-19 06:00AM	Kodiak Sciences to Present at Wedbush PacGrow Healthcare Conference PR Newswire
Jul-27-19 12:47PM	Kodiak Sciences Announces Positive Interim Data from Ongoing Phase 1b Clinical Study of KSI-301, a Novel Anti-VEGF Antibody Biopolymer Conjugate for Treatment of Wet AMD, Diabetic Eye Disease, and Retinal Vein Occlusion, at the American Society of Retina Specialists 2019 Annual Meeting PR Newswire
Jul-24-19 07:00AM	Kodiak Sciences Announces Upcoming Presentation at American Society of Retina Specialists (ASRS) 2019 Annual Meeting PR Newswire
Jul-17-19 10:09AM	Kodiak Sciences' Shares March Higher, Can It Continue? Zacks
Jun-17-19 09:56AM	Kodiak Sciences Inc. (KOD) Shares March Higher, Can It Continue? Zacks
May-30-19 07:27PM	Kodiak Sciences to Present at the Jefferies 2019 Healthcare Conference PR Newswire
May-25-19 10:26AM	How Much Of Kodiak Sciences Inc. (NASDAQ:KOD) Do Insiders Own? Simply Wall St.
May-24-19 09:46AM	Kodiak Sciences Inc. (KOD) Shares March Higher, Can It Continue? Zacks
May-15-19 06:00AM	Kodiak Sciences Announces First Quarter 2019 Financial Results and Recent Business Highlights PR Newswire
May-09-19 07:00AM	Kodiak Sciences to Present at the Bank of America Merrill Lynch Health Care Conference 2019 PR Newswire
Apr-25-19 04:05PM	Kodiak Sciences Announces Presentations at ARVO 2019 Annual Meeting PR Newswire
Mar-28-19 06:00AM	Kodiak Sciences Announces Fourth Quarter and Full Year 2018 Financial Results and Recent Business Highlights PR Newswire
Mar-07-19 06:00AM	Kodiak Sciences to Present at the Barclays Global Healthcare Conference PR Newswire -7.44%
Mar-01-19 10:28AM	The Zacks Analyst Blog Highlights: Microsoft, Kodiak Sciences, General Motors and Procter & Gamble Zacks
Feb-28-19 08:15AM	Wall Street Takes Notice of These 4 Stocks - Should You? Zacks
Feb-27-19 11:00AM	The Smartest People on Wall Street Are Buying These 3 Stocks -- Should You Follow? Motley Fool
Feb-08-19 07:00AM	Kodiak Sciences Announces Upcoming Presentation of KSI-301 12-Week Phase 1a Study Data at Angiogenesis, Exudation, and Degeneration 2019 Meeting PR Newswire
Jan-18-19 10:35AM	Have Insiders Been Buying Kodiak Sciences Inc. (NASDAQ:KOD) Shares? Simply Wall St.
Dec-24-18 08:00AM	Kodiak Sciences Added to Russell 2000®, 3000® and Microcap® Indexes PR Newswire +20.13%
Dec-21-18 06:00AM	Kodiak Sciences Announces Completion of 12-Week Phase 1a Study of KSI-301 in Patients with Diabetic Macular Edema Demonstrating Safety and Durability of Responses Following Single Dose of Intravitreal Anti-VEGF Antibody Biopolymer Conjugate PR Newswire -6.29%
Dec-05-18 10:35AM	This year's Bay Area IPO batch remains up 44% despite market turbulence American City Business Journals
Nov-16-18 06:00AM	Kodiak Sciences Announces Third Quarter 2018 Financial Results and Recent Business Highlights PR Newswire +9.89%
Oct-31-18 03:34PM	Strong IPO pace continued in October but some cracks are showing American City Business Journals
Oct-26-18 03:05PM	Here are 10 Bay Area accelerators ranked as best in the U.S. American City Business Journals
Oct-10-18 07:00AM	Kodiak Sciences Inc. Announces Closing of Initial Public Offering PR Newswire
Oct-04-18 11:35AM	Kodiak Sciences' stock trades little changed in its debut, after the IPO prices well below the expected range MarketWatch

Kodiak Sciences Inc., a clinical stage biopharmaceutical company, provides novel therapeutics to treat retinal diseases. The company's lead product candidate is KSI-301, a vascular endothelial growth factor (VEGF)-biological agent that is in Phase 1b clinical study to treat wet age-related macular degeneration (AMD) and diabetic retinopathy. Its preclinical stage product candidate include KSI-501, a bispecific anti-interleukin 6/VEGF bioconjugate to target inflammation and abnormal angiogenesis in the pathogenesis of retinal vascular diseases. The company's early research pipeline include KSI-601, a triplet inhibitor for dry AMD. The company was formerly known as Oligasis, LLC and changed its name to Kodiak Sciences Inc. in September 2015. Kodiak Sciences Inc. was founded in 2009 and is headquartered in Palo Alto, California.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
EHRLICH JASON	See Remarks	Nov 20	Option Exercise	10.29	6,950	71,516	49,793	Nov 24 06:04 PM
EHRLICH JASON	See Remarks	Nov 20	Sale	138.79	6,950	964,601	42,843	Nov 24 06:04 PM
EHRLICH JASON	See Remarks	Oct 27	Option Exercise	10.29	7,500	77,175	50,343	Oct 29 04:49 PM
EHRLICH JASON	See Remarks	Oct 27	Sale	100.00	7,500	750,000	42,843	Oct 29 04:49 PM
EHRLICH JASON	See Remarks	Oct 23	Option Exercise	10.29	7,500	77,175	50,343	Oct 27 04:57 PM
EHRLICH JASON	See Remarks	Oct 23	Sale	86.25	7,500	646,875	42,843	Oct 27 04:57 PM
EHRLICH JASON	See Remarks	Oct 20	Option Exercise	10.29	6,950	71,516	49,793	Oct 22 04:56 PM
EHRLICH JASON	See Remarks	Oct 20	Sale	78.39	6,950	544,817	42,843	Oct 22 04:56 PM
EHRLICH JASON	See Remarks	Oct 13	Option Exercise	10.29	5,000	51,450	47,843	Oct 15 05:44 PM
EHRLICH JASON	See Remarks	Oct 13	Sale	75.00	5,000	375,000	42,843	Oct 15 05:44 PM
EHRLICH JASON	See Remarks	Oct 09	Sale	71.28	2,200	156,819	42,843	Oct 13 07:04 PM
BAKER BROS. ADVISORS LP	Director	Sep 25	Buy	56.65	48,125	2,726,182	11,324,937	Sep 25 06:02 PM
BAKER BROS. ADVISORS LP	Director	Sep 24	Buy	52.02	36,020	1,873,924	11,280,001	Sep 24 07:30 PM
BAKER BROS. ADVISORS LP	Director	Sep 23	Buy	52.43	92,069	4,826,756	11,246,368	Sep 24 07:30 PM
BAKER BROS. ADVISORS LP	Director	Sep 22	Buy	50.67	74,958	3,797,911	11,160,400	Sep 24 07:30 PM
EHRLICH JASON	See Remarks	Sep 21	Option Exercise	10.29	6,950	71,516	40,934	Sep 23 06:15 PM
EHRLICH JASON	See Remarks	Sep 21	Sale	52.40	6,950	364,182	33,984	Sep 23 06:15 PM
BAKER BROS. ADVISORS LP	Director	Sep 08	Buy	47.34	116,295	5,505,934	11,090,409	Sep 08 05:58 PM
BAKER BROS. ADVISORS LP	Director	Sep 04	Buy	46.73	82,801	3,869,473	10,982,772	Sep 08 05:58 PM
BAKER BROS. ADVISORS LP	Director	Sep 03	Buy	47.97	123,883	5,942,904	10,905,982	Sep 08 05:58 PM
BAKER BROS. ADVISORS LP	Director	Aug 21	Buy	48.63	139,044	6,762,056	10,791,092	Aug 21 05:19 PM
EHRLICH JASON	See Remarks	Aug 20	Option Exercise	10.29	6,950	71,516	40,934	Aug 24 04:56 PM
BAKER BROS. ADVISORS LP	Director	Aug 20	Buy	47.40	60,573	2,871,156	10,662,260	Aug 21 05:19 PM
EHRLICH JASON	See Remarks	Aug 20	Sale	47.11	6,950	327,444	33,984	Aug 24 04:56 PM
BAKER BROS. ADVISORS LP	Director	Aug 19	Buy	46.99	3,869	181,791	10,606,135	Aug 21 05:19 PM
EHRLICH JASON	See Remarks	Jul 20	Option Exercise	10.29	6,950	71,516	40,934	Jul 22 04:47 PM
EHRLICH JASON	See Remarks	Jul 20	Sale	50.44	6,950	350,526	33,984	Jul 22 04:47 PM
EHRLICH JASON	See Remarks	Jul 02	Option Exercise	10.29	2,700	27,783	33,984	Jul 07 07:05 PM
EHRLICH JASON	See Remarks	Jun 22	Option Exercise	10.29	6,950	71,516	38,234	Jun 24 05:09 PM
EHRLICH JASON	See Remarks	Jun 22	Sale	60.54	6,950	420,747	31,284	Jun 24 05:09 PM
EHRLICH JASON	See Remarks	May 20	Option Exercise	10.29	6,950	71,516	38,234	May 22 04:41 PM
EHRLICH JASON	See Remarks	May 20	Sale	60.72	6,950	421,989	31,284	May 22 04:41 PM
EHRLICH JASON	See Remarks	Apr 20	Option Exercise	10.29	6,950	71,516	38,234	Apr 22 05:01 PM
EHRLICH JASON	See Remarks	Apr 20	Sale	54.12	6,950	376,115	31,284	Apr 22 05:01 PM
EHRLICH JASON	See Remarks	Apr 09	Sale	48.56	2,200	106,830	31,284	Apr 13 06:37 PM
Liang Hong	SVP, Discovery Medicine	Apr 02	Sale	42.34	4,000	169,360	130,166	Apr 06 08:08 PM
Liang Hong	SVP, Discovery Medicine	Mar 26	Sale	47.78	4,000	191,112	134,166	Mar 30 04:51 PM
EHRLICH JASON	See Remarks	Mar 20	Option Exercise	10.29	6,950	71,516	29,492	Mar 24 04:45 PM
Levy Richard S	Director	Mar 20	Buy	44.33	1,000	44,330	1,000	Mar 24 04:50 PM
EHRLICH JASON	See Remarks	Mar 20	Sale	45.00	6,950	312,762	22,542	Mar 24 04:45 PM
Liang Hong	SVP, Discovery Medicine	Mar 19	Sale	39.45	4,000	157,811	138,166	Mar 23 04:36 PM
BAKER BROS. ADVISORS LP	Director	Mar 18	Buy	37.37	35,400	1,322,977	10,602,550	Mar 18 06:47 PM
BAKER BROS. ADVISORS LP	Director	Mar 17	Buy	38.99	10,000	389,850	10,570,083	Mar 18 06:47 PM
BAKER BROS. ADVISORS LP	Director	Mar 16	Buy	39.97	104,600	4,180,977	10,560,911	Mar 18 06:47 PM
BAKER BROS. ADVISORS LP	Director	Feb 26	Buy	57.99	100,000	5,799,441	10,464,977	Feb 26 05:06 PM
BAKER BROS. ADVISORS LP	Director	Feb 25	Buy	57.91	206,126	11,937,248	10,373,248	Feb 26 05:06 PM
BAKER BROS. ADVISORS LP	Director	Feb 24	Buy	57.56	71,123	4,093,553	10,184,170	Feb 26 05:06 PM
EHRLICH JASON	See Remarks	Dec 23	Option Exercise	10.29	1,075	11,062	22,542	Dec 27 05:53 PM
BAKER BROS. ADVISORS LP	Director	Dec 06	Buy	46.00	1,902,173	87,499,958	10,118,929	Dec 06 04:46 PM
Liang Hong	SVP, Discovery Medicine	Dec 02	Option Exercise	1.05	42,166	44,111	142,166	Dec 04 05:33 PM

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