TWST Twist Bioscience Corporation Stock Quote

TWST [NASD]

Healthcare | Diagnostics & Research | USA

Index	-	P/E	-	EPS (ttm)	-2.79	Insider Own	2.10%	Shs Outstand	46.00M	Perf Week	9.45%
Market Cap	6.85B	Forward P/E	-	EPS next Y	-2.85	Insider Trans	-36.55%	Shs Float	45.39M	Perf Month	-0.42%
Income	-117.20M	PEG	-	EPS next Q	-0.77	Inst Own	89.60%	Short Float	9.02%	Perf Quarter	-17.32%
Sales	101.10M	P/S	67.80	EPS this Y	8.90%	Inst Trans	1.67%	Short Ratio	3.91	Perf Half Y	57.08%
Book/sh	13.87	P/B	10.15	EPS next Y	6.20%	ROA	-25.60%	Target Price	145.00	Perf Year	431.16%
Cash/sh	12.06	P/C	11.67	EPS next 5Y	-	ROE	-29.50%	52W Range	25.72 - 214.07	Perf YTD	-0.34%
Dividend	-	P/FCF	-	EPS past 5Y	-	ROI	-41.20%	52W High	-34.22%	Beta	-
Dividend %	-	Quick Ratio	16.70	Sales past 5Y	-	Gross Margin	34.90%	52W Low	447.47%	ATR	11.69
Employees	525	Current Ratio	17.10	Sales Q/Q	64.00%	Oper. Margin	-	RSI (14)	56.44	Volatility	5.62% 8.88%
Optionable	Yes	Debt/Eq	0.01	EPS Q/Q	57.60%	Profit Margin	-	Rel Volume	0.65	Prev Close	129.01
Shortable	Yes	LT Debt/Eq	0.00	Earnings	Feb 04 AMC	Payout	-	Avg Volume	1.05M	Price	140.81
Recom	2.60	SMA20	10.91%	SMA50	-0.48%	SMA200	31.49%	Volume	677,497	Change	9.15%

Apr-12-21

Initiated

Piper Sandler

Overweight

$150

Feb-05-21

Downgrade

JP Morgan

Neutral → Underweight

$100

Jan-04-21

Downgrade

Evercore ISI

Outperform → In-line

Oct-20-20

Initiated

SVB Leerink

Mkt Perform

$90

May-31-19

Initiated

Evercore ISI

Outperform

Nov-26-18

Initiated

JP Morgan

Neutral

$27

Apr-12-21 08:00AM	Twist Bioscience Exercises Option to Purchase Custom Designed Antibody Library and Optimization Software Business Wire
Apr-07-21 10:00PM	AcornMed Selects Twist Bioscience Technology to Power Next Generation Precision Medicine Tests Business Wire
08:00AM	Twist Bioscience to Provide Antibody Discovery, Optimization and Access to Library of Libraries for Drug Research to Stanford University Laboratories Business Wire
Apr-05-21 08:00AM	Twist Bioscience Earns 2021 Great Place to Work Certification Business Wire
Apr-01-21 07:31AM	These 3 Stocks Will Make You A Fortune If They Succeed Motley Fool
Mar-25-21 08:29AM	Twist Bioscience and Kyowa Kirin Partner for GPCR Antibody Discovery Business Wire
Mar-24-21 08:36AM	Twist's COVID-19 test, which can detect variants, gets authorized MarketWatch -10.91%
08:00AM	Twist Bioscience and Biotia Receive U.S. FDA Emergency Use Authorization for First Hybridization Capture-Based Next-Generation Sequencing SARS-CoV-2 Assay Business Wire
Mar-23-21 02:14PM	2 Under-the-Radar Nasdaq Stocks Cathie Wood Loves Right Now Motley Fool
Mar-22-21 08:00AM	Twist Bioscience Functional GLP-1R Antibodies Identified From Its Proprietary Synthetic DNA GPCR Libraries Demonstrate Potent Blood Glucose Control Business Wire
Mar-15-21 08:00AM	Twist Bioscience Begins Shipping of Synthetic RNA Controls for B.1.351 and P.1 Variants Business Wire
Mar-09-21 07:00AM	Twist Bioscience Named to Fast Companys Annual List of the Worlds Most Innovative Companies for 2021 Business Wire +18.53%
Mar-06-21 09:26AM	Cathie Woods Top 10 Stock Picks Insider Monkey
Mar-02-21 08:00AM	Twist Bioscience and Watchmaker Genomics Announce Partnership to Drive New Applications of High-throughput Genetic Sequencing Business Wire
Mar-01-21 08:00AM	Twist Bioscience to Highlight Genotyping by Sequencing and Methylation Solution During AGBT Business Wire +5.31%
Feb-24-21 11:06AM	Twist Bioscience Launches Methylation Detection Systems Benzinga +5.11%
08:00AM	Twist Bioscience Launches Industry-Leading NGS Methylation Detection System for Liquid Biopsy Cancer Analysis and Epigenetic Studies Business Wire
04:36AM	If You Had Bought Twist Bioscience (NASDAQ:TWST) Stock A Year Ago, You Could Pocket A 327% Gain Today Simply Wall St.
Feb-22-21 05:00AM	Twist Bioscience and Berry Genomics to Offer New NGS Solution to Advance Research and Precision Medicine Business Wire -9.02%
Feb-19-21 08:00AM	Twist Bioscience to Present at Upcoming Virtual Conferences Business Wire
Feb-18-21 09:00AM	Twist Bioscience and Victorian Clinical Genetic Services Collaborate on Development of Novel Whole Exome Capture Diagnostic Assay Business Wire
Feb-05-21 11:33AM	Why Twist Bioscience Stock Is Tanking Today Motley Fool -20.05%
11:09AM	Twist Bioscience Drops Most in 10 Months After JPMorgan Downgrade TheStreet.com
12:01AM	Twist Bioscience Corp (TWST) Q1 2021 Earnings Call Transcript Motley Fool
Feb-04-21 06:05PM	Twist Bioscience (TWST) Reports Q1 Loss, Tops Revenue Estimates Zacks
05:06PM	Recap: Twist Bioscience Q1 Earnings Benzinga
04:05PM	Twist Bioscience Reports First Quarter Fiscal 2021 Financial Results Business Wire
02:45PM	Twist Bioscience Corp. to Host Earnings Call ACCESSWIRE
Feb-03-21 10:17AM	Earnings Outlook For Twist Bioscience Benzinga
08:00AM	Twist Bioscience Announces Executive Team Appointments Business Wire
Jan-28-21 12:32PM	Twist Bioscience (TWST) May Report Negative Earnings: Know the Trend Ahead of Q1 Release Zacks +6.07%
08:00AM	Twist Bioscience to Report Fiscal 2021 First Quarter Financial Results on Thursday, February 4, 2020 Business Wire
Jan-20-21 11:28AM	A Deep Dive into ARK ETFs Zacks
Jan-19-21 08:00AM	Twist Bioscience Signs Two Biopharma Technology Agreements to Enable Novel Therapeutics Discovery Business Wire +13.31%
Jan-14-21 12:27PM	Want to Use ETFs to Play Biotech? Choose Wisely. Barrons.com +12.48%
08:00AM	Twist Bioscience Begins Shipping of Synthetic RNA Controls for UK Variant Strain of SARS-CoV-2 Business Wire
Jan-11-21 05:12PM	SKB finalizes new lease agreement with Twist Bioscience Corporation ("Twist") at recently repositioned mixed-use campus, ParkWorks Industrial Center PR Newswire
Jan-07-21 08:00AM	Twist Bioscience Supplies Centers for Disease Control and Prevention with Custom SARS-CoV-2 Synthetic RNA Controls Business Wire +9.45%
Jan-04-21 08:00AM	Twist Bioscience to Present at the 39th Annual J.P. Morgan Healthcare Conference Business Wire -5.92%
Dec-31-20 05:00AM	The Best Stock Picker of 2020 Wins With Disruptive DNA Bloomberg
Dec-23-20 08:00AM	Twist Bioscience to Offer Synthetic RNA Control for UK Variant Strain of SARS-CoV-2 Business Wire
Dec-22-20 08:00AM	Twist Bioscience to Expand Commercial Capabilities with Factory of the Future Business Wire +10.45%
Dec-21-20 06:42PM	How a Relentless Dealmaker Cracked Silicon Valleys Bros Club Bloomberg
Dec-18-20 10:20PM	Is TWST A Good Stock To Buy Now According To Hedge Funds? Insider Monkey
Dec-10-20 08:00AM	Twist Bioscience Expands Gene Product Line with Launch of Clonal-Ready Gene Fragments Business Wire +8.17%
Dec-07-20 04:05PM	Twist Bioscience Announces Closing of Upsized Public Offering of Common Stock and Full Exercise of Underwriters Option to Purchase Additional Shares Business Wire
Dec-02-20 08:34PM	Twist Bioscience Announces Pricing of a $300 Million Upsized Public Offering of Common Stock Business Wire
Dec-01-20 04:01PM	Twist Bioscience Announces Proposed Public Offering of Common Stock Business Wire +5.69%
Nov-26-20 02:15AM	Earnings Update: Here's Why Analysts Just Lifted Their Twist Bioscience Corporation (NASDAQ:TWST) Price Target To US$110 Simply Wall St.
Nov-24-20 08:00AM	Twist Bioscience to Present at Upcoming Virtual Investor Conferences Business Wire -11.11%
Nov-23-20 06:00PM	Twist Bioscience Corp (TWST) Q4 2020 Earnings Call Transcript Motley Fool
07:54AM	Twist Bioscience: Q4 Earnings Insights Benzinga
07:01AM	Twist Bioscience Reports Fourth Quarter and Full Year Fiscal 2020 Financial Results Business Wire
07:00AM	Twist Bioscience Announces Positive Preclinical Data for SARS-CoV-2 Antibodies Business Wire
06:15AM	Twist Bioscience Corp. to Host Earnings Call ACCESSWIRE
Nov-20-20 10:04AM	Earnings Preview for Twist Bioscience Benzinga
Nov-19-20 08:00AM	Twist Bioscience and Biotia Announce Research Use Only Availability of First Hybridization Capture-Based Next-Generation Sequencing SARS-CoV-2 Assay for Characterization and Surveillance of the Virus Business Wire
Nov-18-20 08:00AM	Twist Bioscience Ranked 60th Fastest Growing Company in North America on Deloittes 2020 Fast 500 Business Wire
Nov-16-20 12:30PM	Will Twist Bioscience (TWST) Report Negative Earnings Next Week? What You Should Know Zacks
08:00AM	Twist Bioscience Expands Infectious Disease Product Line Adding Comprehensive Viral Panel Business Wire
07:59AM	Twist Bioscience Continues Support for Next Generation of Synthetic Biologists Through Work with iGEM Competition Business Wire
Nov-12-20 03:15PM	Twist Bioscience, Illumina and Western Digital Form Alliance with Microsoft to Advance Data Storage in DNA Business Wire
Nov-10-20 08:00AM	Twist Bioscience to Present at the Stifel 2020 Virtual Healthcare Conference Business Wire
Nov-02-20 08:00AM	Twist Bioscience to Report Fiscal 2020 Fourth Quarter and Full Year Financial Results on Monday, November 23, 2020 Business Wire
Oct-29-20 08:00AM	Twist Bioscience Showcases Next-Generation Sequencing Presentations at Virtual American Society for Human Genetics 2020 Annual Meeting Business Wire
Oct-27-20 08:00AM	Twist Bioscience Collaborates With Beyond Earth to Launch Artwork Stored in DNA Into Space Business Wire
Oct-20-20 09:56AM	Benzinga's Top Upgrades, Downgrades For October 20, 2020 Benzinga
Oct-13-20 03:03PM	Hedge Funds Cant Stop Buying Twist Bioscience Corporation (TWST) Insider Monkey
08:00AM	Twist Bioscience to Host Virtual Biopharma Analyst & Investor Event on October 23, 2020 Business Wire
07:00AM	Twist Bioscience and Neogene Announce Broad Strategic Partnership for Next Generation Personalized T Cell Therapies Business Wire
Sep-18-20 08:00AM	Emily Leproust, Ph.D., to Receive 2020 Rosalind Franklin Award Business Wire
Sep-16-20 01:38PM	Shareholders Are Thrilled That The Twist Bioscience (NASDAQ:TWST) Share Price Increased 107% Simply Wall St.
Sep-03-20 08:00AM	Twist Bioscience to Present at Upcoming Virtual Investor Conferences Business Wire
Sep-02-20 08:00AM	Twist Bioscience Announces Potent SARS-CoV-2 Neutralizing Data from COVID-19 Therapeutic Antibody Program Business Wire
Aug-20-20 08:00AM	Twist Bioscience Synthetic DNA Stores New Netflix Original Series BIOHACKERS Business Wire
Aug-13-20 10:35AM	Twist Bioscience Is Rapidly Growing Its Customer Base. Can It Turn a Profit? Motley Fool
Aug-06-20 07:10PM	Twist Bioscience (TWST) Reports Q3 Loss, Tops Revenue Estimates Zacks
04:05PM	Twist Bioscience Reports Third Quarter Fiscal 2020 Financial Results Business Wire
Aug-04-20 08:00AM	Seismic Bio Partners With Twist Bioscience for Discovery and Optimization of Antibodies Business Wire +5.61%
Jul-30-20 12:34PM	Will Twist Bioscience (TWST) Report Negative Q3 Earnings? What You Should Know Zacks
08:00AM	Twist Bioscience to Report Fiscal 2020 Third Quarter Financial Results on Thursday, August 6, 2020 Business Wire
Jul-28-20 08:00AM	Twist Bioscience Launches Two SARS-CoV-2 Antibody Panels to Expedite Research for COVID-19 Business Wire
Jul-23-20 08:00AM	Twist Bioscience Appoints Erin Smith Senior Vice President, Government Affairs and Public Policy Business Wire
Jul-22-20 08:21AM	Twist Bioscience Has Gained 186% in 2020. Is the Synbio Stock a Buy? Motley Fool
08:00AM	Twist Bioscience Launches Synthetic Controls for Respiratory Viruses Business Wire
Jul-16-20 08:00AM	Twist Bioscience Partners with Invetx to Deliver Best-in-Class Antibody Therapeutics for Dogs and Cats Business Wire -5.43%
Jul-15-20 02:20PM	Twist Bioscience Customer Vanderbilt University Medical Center (VUMC) Announces Publication of Positive Preclinical Results on Neutralizing Antibodies as a Potential Therapy for Preventing and Treating COVID-19 Business Wire
Jul-08-20 08:00AM	Takeda Partners with Twist Bioscience to Expand Biologics Discovery Capabilities Business Wire +11.82%
Jul-01-20 08:12AM	The Daily Biotech Pulse: T2 Biosystems Launches COVID-19 Test, Akero Aces Midstage NASH Study, Aravive Added to Russell Indexes Benzinga
Jun-30-20 08:00AM	Twist Bioscience Adds Respiratory Virus Panel to Infectious Disease Product Line Business Wire +7.83%
Jun-28-20 05:23PM	Hedge Funds Keep Buying Twist Bioscience Corporation (TWST) Insider Monkey
Jun-11-20 08:00AM	Twist Bioscience Expands Offering of Synthetic SARS-CoV-2 RNA Controls Business Wire -7.57%
Jun-09-20 08:30AM	Twist Bioscience Partners with Serimmune to Identify SARS-CoV-2 Therapeutic Antibody Candidates PR Newswire
Jun-08-20 04:05PM	Twist Bioscience Announces Closing of Public Offering of Common Stock and Full Exercise of Underwriters Option to Purchase Additional Shares Business Wire
Jun-03-20 10:16PM	Twist Bioscience Announces Pricing of a $100 Million Public Offering of Common Stock Business Wire
04:27PM	Twist Bioscience Announces Proposed Public Offering of Common Stock Business Wire
Jun-01-20 08:00AM	Twist Bioscience to Join Proteona in Global Alliance to Protect Immunocompromised Patients From COVID-19 Infection Business Wire +5.40%
May-26-20 08:00AM	Twist Bioscience to Present at the Jefferies Virtual Healthcare Conference Business Wire -5.15%
May-17-20 04:15PM	Schrodinger Shares Have More Than Tripled Since IPO GuruFocus.com
May-12-20 08:00AM	Twist Bioscience to Participate in the UBS Virtual Global Healthcare Conference Business Wire

Twist Bioscience Corporation, a synthetic biology company, manufactures and sells synthetic DNA-based products. The company's DNA synthesis platform enables the manufacturing of synthetic DNA by writing DNA on a silicon chip. It offers synthetic DNA-based products, including synthetic genes, tools for sample preparation, antibody libraries for drug discovery and development, and DNA as a digital data storage medium. The company has a collaboration agreements with ImmunoPrecise Antibodies Ltd.; Victorian Clinical Genetic Services; and Kyowa Kirin Pharmaceutical Research, Inc. Twist Bioscience Corporation was founded in 2013 and is headquartered in South San Francisco, California.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Finn Patrick John	Chief Commercial Officer	Apr 05	Option Exercise	23.28	2,702	62,895	45,446	Apr 07 06:44 PM
Finn Patrick John	Chief Commercial Officer	Apr 05	Sale	126.72	2,702	342,397	42,744	Apr 07 06:44 PM
Daniels Mark	See Remarks	Mar 29	Option Exercise	8.82	377	3,325	67,303	Mar 31 04:30 PM
Daniels Mark	See Remarks	Mar 29	Sale	114.39	377	43,125	66,926	Mar 31 04:30 PM
Weiss Patrick	Chief Operating Officer	Mar 24	Option Exercise	15.46	14,639	226,343	67,358	Mar 26 04:30 PM
Daniels Mark	See Remarks	Mar 24	Option Exercise	23.33	620	14,465	67,546	Mar 26 04:30 PM
Weiss Patrick	Chief Operating Officer	Mar 24	Sale	132.50	14,639	1,939,668	52,719	Mar 26 04:30 PM
Daniels Mark	See Remarks	Mar 24	Sale	132.50	620	82,150	66,926	Mar 26 04:30 PM
Banyai William	See Remarks	Mar 22	Sale	132.61	20,000	2,652,189	420,987	Mar 24 04:30 PM
Leproust Emily M.	President & CEO	Mar 12	Sale	139.72	2,000	279,435	268,556	Mar 16 05:35 PM
Daniels Mark	See Remarks	Mar 04	Option Exercise	10.70	669	7,158	67,595	Mar 05 04:15 PM
Daniels Mark	See Remarks	Mar 04	Sale	125.33	669	83,846	66,926	Mar 05 04:15 PM
RAGUSA ROBERT P	Director	Mar 03	Option Exercise	30.41	10,588	321,981	12,486	Mar 05 04:50 PM
RAGUSA ROBERT P	Director	Mar 03	Sale	133.05	10,588	1,408,745	1,898	Mar 05 04:50 PM
Finn Patrick John	Chief Commercial Officer	Mar 02	Option Exercise	23.28	2,702	62,895	45,702	Mar 04 04:46 PM
Finn Patrick John	Chief Commercial Officer	Mar 02	Sale	145.35	2,702	392,736	43,000	Mar 04 04:46 PM
Daniels Mark	See Remarks	Mar 01	Option Exercise	22.30	1,543	34,411	68,469	Mar 03 04:36 PM
Daniels Mark	See Remarks	Mar 01	Sale	140.78	1,543	217,224	66,926	Mar 03 04:36 PM
Daniels Mark	See Remarks	Feb 24	Option Exercise	23.33	620	14,465	67,546	Feb 26 06:49 PM
Daniels Mark	See Remarks	Feb 24	Sale	134.31	620	83,272	66,926	Feb 26 06:49 PM
Finn Patrick John	Chief Commercial Officer	Feb 24	Sale	134.31	183	24,579	43,000	Feb 26 06:48 PM
Green Paula	SVP of Human Resources	Feb 22	Sale	146.98	492	72,314	21,679	Feb 24 05:22 PM
Banyai William	See Remarks	Feb 22	Sale	145.99	20,275	2,959,971	440,987	Feb 24 05:22 PM
Daniels Mark	See Remarks	Feb 22	Sale	146.98	981	144,187	66,926	Feb 24 05:21 PM
Leproust Emily M.	President & CEO	Feb 12	Sale	167.64	2,000	335,278	318,188	Feb 17 04:53 PM
BARTHELEMY NICOLAS	Director	Feb 09	Option Exercise	23.33	5,000	116,650	6,898	Feb 11 04:39 PM
Leproust Emily M.	President & CEO	Feb 09	Sale	176.53	75,000	13,239,753	0	Feb 11 04:38 PM
BARTHELEMY NICOLAS	Director	Feb 09	Sale	177.61	5,000	888,034	1,898	Feb 11 04:39 PM
CHESS ROBERT	Director	Feb 05	Sale	159.54	706	112,635	71,014	Feb 09 06:17 PM
Daniels Mark	See Remarks	Feb 04	Option Exercise	10.70	668	7,148	68,868	Feb 08 05:25 PM
Daniels Mark	See Remarks	Feb 04	Sale	191.52	668	127,935	68,200	Feb 08 05:25 PM
Finn Patrick John	Chief Commercial Officer	Feb 02	Option Exercise	23.28	2,702	62,895	46,729	Feb 04 04:57 PM
Finn Patrick John	Chief Commercial Officer	Feb 02	Sale	183.59	2,702	496,060	44,027	Feb 04 04:57 PM
Daniels Mark	See Remarks	Feb 01	Option Exercise	26.66	1,166	31,086	69,366	Feb 03 04:54 PM
Daniels Mark	See Remarks	Feb 01	Sale	166.74	1,166	194,419	68,200	Feb 03 04:54 PM
Daniels Mark	See Remarks	Jan 28	Option Exercise	8.82	377	3,325	68,577	Feb 01 06:00 PM
Daniels Mark	See Remarks	Jan 28	Sale	161.02	377	60,705	68,200	Feb 01 06:00 PM
Daniels Mark	See Remarks	Jan 25	Option Exercise	23.33	620	14,465	68,820	Jan 26 05:48 PM
Green Paula	SVP of Human Resources	Jan 25	Sale	193.00	246	47,478	22,250	Jan 26 05:49 PM
Banyai William	See Remarks	Jan 25	Sale	192.54	14,099	2,714,617	461,937	Jan 26 05:48 PM
Daniels Mark	See Remarks	Jan 25	Sale	193.00	905	174,665	68,200	Jan 26 05:48 PM
Leproust Emily M.	President & CEO	Jan 20	Sale	209.73	5,000	1,048,636	396,196	Jan 21 04:30 PM
Leproust Emily M.	President & CEO	Jan 19	Sale	200.41	20,000	4,008,132	401,196	Jan 21 04:30 PM
Leproust Emily M.	President & CEO	Jan 14	Sale	184.34	10,000	1,843,356	421,196	Jan 19 05:02 PM
Leproust Emily M.	President & CEO	Jan 12	Sale	166.88	2,000	333,751	431,196	Jan 14 04:30 PM
Finn Patrick John	Chief Commercial Officer	Jan 05	Option Exercise	23.28	2,702	62,895	46,930	Jan 07 04:50 PM
Finn Patrick John	Chief Commercial Officer	Jan 05	Sale	132.93	2,702	359,177	44,228	Jan 07 04:50 PM
Daniels Mark	See Remarks	Jan 04	Option Exercise	10.70	669	7,158	69,303	Jan 05 05:52 PM
Daniels Mark	See Remarks	Jan 04	Sale	138.61	669	92,730	68,634	Jan 05 05:52 PM
Daniels Mark	See Remarks	Dec 31	Option Exercise	26.66	1,166	31,086	69,953	Jan 05 05:52 PM
Daniels Mark	See Remarks	Dec 31	Sale	152.13	1,166	177,384	68,787	Jan 05 05:52 PM
Daniels Mark	See Remarks	Dec 28	Option Exercise	8.82	377	3,325	69,164	Dec 29 05:53 PM
Daniels Mark	See Remarks	Dec 28	Sale	167.10	377	62,997	68,787	Dec 29 05:53 PM
Daniels Mark	See Remarks	Dec 24	Option Exercise	23.33	620	14,465	69,407	Dec 29 05:53 PM
Leproust Emily M.	President & CEO	Dec 24	Option Exercise	5.95	5,300	31,535	433,959	Dec 28 08:00 PM
Daniels Mark	See Remarks	Dec 24	Sale	167.79	620	104,030	68,787	Dec 29 05:53 PM
Leproust Emily M.	President & CEO	Dec 23	Sale	169.31	5,000	846,531	428,659	Dec 28 08:00 PM
Leproust Emily M.	President & CEO	Dec 22	Sale	160.12	5,000	800,583	433,659	Dec 23 04:33 PM
Daniels Mark	See Remarks	Dec 21	Option Exercise	9.67	12,451	120,393	68,787	Dec 23 04:32 PM
Leproust Emily M.	President & CEO	Dec 21	Sale	150.33	10,000	1,503,336	438,659	Dec 22 05:31 PM
Leproust Emily M.	President & CEO	Dec 18	Sale	144.99	2,000	289,972	448,659	Dec 22 05:31 PM
Daniels Mark	See Remarks	Dec 15	Option Exercise	18.11	68,844	1,246,597	126,811	Dec 17 07:25 PM
Banyai William	See Remarks	Dec 15	Sale	132.66	20,000	2,653,185	476,440	Dec 17 07:27 PM
Green Paula	SVP of Human Resources	Dec 15	Sale	139.73	4,634	647,509	22,804	Dec 17 07:26 PM
Leproust Emily M.	President & CEO	Dec 15	Sale	134.24	70,000	9,396,516	450,659	Dec 17 07:26 PM
Daniels Mark	See Remarks	Dec 15	Sale	132.67	70,475	9,350,205	56,336	Dec 17 07:25 PM
Weiss Patrick	Chief Operating Officer	Dec 14	Option Exercise	24.62	40,000	984,825	94,350	Dec 16 05:47 PM
Weiss Patrick	Chief Operating Officer	Dec 14	Sale	144.00	40,000	5,760,161	54,350	Dec 16 05:47 PM
Weiss Patrick	Chief Operating Officer	Dec 11	Option Exercise	8.71	3,558	30,994	57,773	Dec 14 05:42 PM
Weiss Patrick	Chief Operating Officer	Dec 11	Sale	151.13	3,558	537,721	54,350	Dec 14 05:42 PM
THORBURN JAMES M	Chief Financial Officer	Dec 10	Option Exercise	15.11	20,000	302,146	69,718	Dec 14 05:43 PM
Weiss Patrick	Chief Operating Officer	Dec 10	Option Exercise	8.71	3,550	30,935	57,769	Dec 14 05:42 PM
Weiss Patrick	Chief Operating Officer	Dec 10	Sale	138.62	3,550	492,101	54,350	Dec 14 05:42 PM
THORBURN JAMES M	Chief Financial Officer	Dec 10	Sale	149.11	20,018	2,984,890	49,700	Dec 14 05:43 PM
Finn Patrick John	Chief Commercial Officer	Dec 07	Option Exercise	21.13	25,845	546,141	70,267	Dec 09 04:30 PM
Finn Patrick John	Chief Commercial Officer	Dec 07	Sale	131.46	25,845	3,397,582	44,422	Dec 09 04:30 PM
CRANDELL KEITH	Director	Dec 07	Sale	103.40	75,000	7,755,000	288,104	Dec 09 05:11 PM
Banyai William	See Remarks	Nov 30	Sale	113.65	2,790	317,084	496,440	Dec 02 04:25 PM
Weiss Patrick	Chief Operating Officer	Nov 13	Option Exercise	8.71	3,550	30,935	58,997	Nov 16 05:39 PM
Weiss Patrick	Chief Operating Officer	Nov 13	Sale	107.20	3,550	380,560	55,578	Nov 16 05:39 PM
Weiss Patrick	Chief Operating Officer	Nov 12	Option Exercise	8.71	3,550	30,935	58,997	Nov 16 05:39 PM
Weiss Patrick	Chief Operating Officer	Nov 12	Sale	102.90	3,550	365,295	55,578	Nov 16 05:39 PM
Weiss Patrick	Chief Operating Officer	Oct 09	Option Exercise	8.71	3,550	30,935	60,118	Oct 13 04:09 PM
Weiss Patrick	Chief Operating Officer	Oct 09	Sale	86.63	3,550	307,536	56,699	Oct 13 04:09 PM
Weiss Patrick	Chief Operating Officer	Oct 08	Option Exercise	8.71	3,550	30,935	60,118	Oct 13 04:09 PM
Weiss Patrick	Chief Operating Officer	Oct 08	Sale	89.58	3,550	318,009	56,699	Oct 13 04:09 PM
Weiss Patrick	Chief Operating Officer	Sep 18	Option Exercise	8.71	3,550	30,935	60,118	Sep 21 04:58 PM
Weiss Patrick	Chief Operating Officer	Sep 18	Sale	65.21	3,550	231,495	56,699	Sep 21 04:58 PM
Weiss Patrick	Chief Operating Officer	Sep 17	Option Exercise	8.71	3,550	30,935	67,689	Sep 21 04:58 PM
Weiss Patrick	Chief Operating Officer	Sep 17	Sale	60.75	11,121	675,601	56,699	Sep 21 04:58 PM
Green Paula	VP of Human Resources	Sep 16	Option Exercise	6.92	26,988	186,825	46,458	Sep 18 05:08 PM
Green Paula	VP of Human Resources	Sep 16	Sale	63.37	26,988	1,710,100	28,615	Sep 18 05:08 PM
THORBURN JAMES M	Chief Financial Officer	Sep 09	Option Exercise	26.66	20,000	533,200	71,719	Sep 11 04:13 PM
THORBURN JAMES M	Chief Financial Officer	Sep 09	Sale	65.96	20,000	1,319,124	51,719	Sep 11 04:13 PM
THORBURN JAMES M	Chief Financial Officer	Sep 08	Option Exercise	13.87	70,000	970,876	111,130	Sep 09 06:03 PM
Leproust Emily M.	President & CEO	Sep 08	Sale	60.35	3,482	210,156	607,698	Sep 09 06:04 PM
THORBURN JAMES M	Chief Financial Officer	Sep 08	Sale	63.08	70,000	4,415,790	51,719	Sep 09 06:03 PM
THORBURN JAMES M	Chief Financial Officer	Sep 04	Option Exercise	11.59	30,000	347,700	81,719	Sep 09 06:03 PM
Leproust Emily M.	President & CEO	Sep 04	Sale	63.08	96,518	6,088,154	611,180	Sep 09 06:04 PM
THORBURN JAMES M	Chief Financial Officer	Sep 04	Sale	63.58	30,000	1,907,309	51,719	Sep 09 06:03 PM

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