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| Latest Insider Trading | Top Insider Trading Recent Week | Top 10% Owner Trading Recent Week | Filter
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| Ticker | Owner | Relationship | Date | Transaction | Cost  |
#Shares | Value ($) | #Shares Total | SEC Form 4 |
| TELA | Opaleye Management Inc. | 10% Owner | Jul 01 | Buy | 7.00 | 200 | 1,400 | 98,567 | Jul 05 06:30 PM |
| TELA | Opaleye Management Inc. | 10% Owner | Jun 29 | Buy | 6.99 | 2 | 14 | 1,542,002 | Jun 30 07:20 PM |
| TELA | Opaleye Management Inc. | 10% Owner | Jun 30 | Buy | 7.00 | 3,565 | 24,955 | 1,545,000 | Jun 30 07:20 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Jun 24 | Buy | 1.39 | 11,419 | 15,894 | 348,733 | Jun 27 04:05 PM |
| TELA | Opaleye Management Inc. | 10% Owner | Jun 22 | Buy | 6.99 | 2,400 | 16,776 | 1,542,000 | Jun 24 07:45 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Jun 21 | Buy | 1.31 | 841,989 | 1,105,279 | 3,776,589 | Jun 23 06:54 PM |
| TELA | Opaleye Management Inc. | 10% Owner | Jun 10 | Buy | 6.50 | 2,400 | 15,599 | 97,400 | Jun 22 05:18 PM |
| TELA | Opaleye Management Inc. | 10% Owner | Jun 22 | Buy | 6.50 | 50,000 | 324,975 | 1,540,000 | Jun 22 05:18 PM |
| TELA | Opaleye Management Inc. | 10% Owner | Jun 10 | Buy | 5.60 | 27,500 | 154,066 | 1,490,000 | Jun 10 06:16 PM |
| TCON | Opaleye Management Inc. | 10% Owner | May 10 | Buy | 1.76 | 9,700 | 17,032 | 2,934,600 | May 10 07:58 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Apr 22 | Buy | 1.98 | 7,100 | 14,058 | 2,926,100 | Apr 29 06:27 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Apr 22 | Buy | 2.24 | 42,000 | 93,941 | 2,910,000 | Apr 25 05:55 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Apr 25 | Buy | 2.18 | 10,777 | 23,497 | 2,920,000 | Apr 25 05:55 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Apr 13 | Buy | 2.50 | 7,345 | 18,361 | 2,862,296 | Apr 14 06:13 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Apr 14 | Buy | 2.50 | 12,696 | 31,730 | 2,872,296 | Apr 14 06:13 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Apr 12 | Buy | 6.75 | 28,557 | 192,717 | 3,165,000 | Apr 13 06:33 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Apr 13 | Buy | 6.76 | 12,832 | 86,785 | 3,175,000 | Apr 13 06:33 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Apr 11 | Buy | 2.42 | 9,100 | 22,019 | 2,844,198 | Apr 12 07:38 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Apr 12 | Buy | 2.48 | 18,098 | 44,827 | 2,857,296 | Apr 12 07:38 PM |
| TARA | Opaleye Management Inc. | 10% Owner | Apr 07 | Buy | 4.74 | 2,345 | 11,123 | 2,551,345 | Apr 08 06:45 PM |
| TARA | Opaleye Management Inc. | 10% Owner | Apr 08 | Buy | 4.80 | 7,791 | 37,364 | 2,556,667 | Apr 08 06:45 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Mar 16 | Buy | 2.20 | 2,235 | 4,917 | 2,837,735 | Mar 17 04:05 PM |
| TARA | Opaleye Management Inc. | 10% Owner | Jan 28 | Buy | 4.96 | 24,031 | 119,271 | 2,550,000 | Jan 31 04:05 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Jan 28 | Buy | 2.20 | 500 | 1,100 | 2,820,500 | Jan 31 04:05 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Jan 28 | Buy | 6.89 | 6,343 | 43,686 | 3,140,000 | Jan 31 04:05 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Jan 21 | Buy | 2.19 | 35,000 | 76,811 | 2,820,000 | Jan 24 06:18 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Jan 24 | Buy | 2.05 | 17,363 | 35,603 | 2,835,000 | Jan 24 06:18 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Jan 19 | Buy | 2.24 | 23,688 | 53,080 | 2,770,000 | Jan 21 04:00 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Jan 20 | Buy | 2.25 | 21,312 | 47,952 | 2,790,000 | Jan 21 04:00 PM |
| TARA | Opaleye Management Inc. | 10% Owner | Dec 28 | Buy | 6.36 | 7,091 | 45,090 | 2,530,000 | Dec 29 07:36 PM |
| TARA | Opaleye Management Inc. | 10% Owner | Dec 29 | Buy | 6.98 | 4,500 | 31,408 | 120,000 | Dec 29 07:36 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Dec 29 | Buy | 2.51 | 52,325 | 131,362 | 2,750,000 | Dec 29 07:14 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Dec 27 | Buy | 2.92 | 87,325 | 255,103 | 2,592,371 | Dec 29 04:05 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Dec 28 | Buy | 2.63 | 20,125 | 52,950 | 2,717,675 | Dec 29 04:05 PM |
| TARA | Opaleye Management Inc. | 10% Owner | Dec 23 | Buy | 6.60 | 1,300 | 8,580 | 2,496,709 | Dec 27 06:52 PM |
| TARA | Opaleye Management Inc. | 10% Owner | Dec 27 | Buy | 6.53 | 36,700 | 239,713 | 2,528,409 | Dec 27 06:52 PM |
| TARA | Opaleye Management Inc. | 10% Owner | Dec 20 | Buy | 6.49 | 703 | 4,562 | 2,496,209 | Dec 22 04:05 PM |
| TARA | Opaleye Management Inc. | 10% Owner | Dec 16 | Buy | 6.41 | 7,563 | 48,485 | 2,493,206 | Dec 20 04:00 PM |
| TARA | Opaleye Management Inc. | 10% Owner | Dec 17 | Buy | 6.60 | 2,790 | 18,414 | 2,495,506 | Dec 20 04:00 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Dec 15 | Buy | 2.43 | 21,964 | 53,287 | 2,517,371 | Dec 16 04:01 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Dec 13 | Buy | 2.64 | 15,204 | 40,154 | 2,462,371 | Dec 15 04:05 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Dec 14 | Buy | 2.53 | 42,000 | 106,344 | 2,497,371 | Dec 15 04:05 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Dec 03 | Buy | 2.30 | 89,274 | 204,911 | 2,428,371 | Dec 07 04:05 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Dec 06 | Buy | 2.26 | 22,733 | 51,474 | 2,448,371 | Dec 07 04:05 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Dec 01 | Buy | 2.40 | 50,000 | 120,160 | 2,338,371 | Dec 03 05:14 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Dec 02 | Buy | 2.35 | 10,500 | 24,660 | 2,348,371 | Dec 03 05:14 PM |
| TARA | Opaleye Management Inc. | 10% Owner | Nov 17 | Buy | 6.98 | 9,118 | 63,644 | 2,472,500 | Nov 19 04:10 PM |
| TARA | Opaleye Management Inc. | 10% Owner | Nov 18 | Buy | 6.98 | 15,206 | 106,130 | 2,486,706 | Nov 19 04:10 PM |
| ETON | Opaleye Management Inc. | 10% Owner | Nov 17 | Sale | 4.67 | 25,000 | 116,712 | 2,375,000 | Nov 19 04:09 PM |
| ETON | Opaleye Management Inc. | 10% Owner | Nov 15 | Sale | 4.80 | 3,000 | 14,405 | 85,938 | Nov 17 04:33 PM |
| ETON | Opaleye Management Inc. | 10% Owner | Nov 16 | Sale | 4.86 | 12,438 | 60,472 | 85,000 | Nov 17 04:33 PM |
| ETON | Opaleye Management Inc. | 10% Owner | Nov 05 | Sale | 6.30 | 167,701 | 1,056,701 | 89,099 | Nov 09 04:46 PM |
| ETON | Opaleye Management Inc. | 10% Owner | Nov 08 | Sale | 6.10 | 52,661 | 321,285 | 86,438 | Nov 09 04:46 PM |
| TARA | Opaleye Management Inc. | 10% Owner | Nov 04 | Buy | 6.50 | 6,557 | 42,620 | 2,464,472 | Nov 08 02:30 PM |
| ETON | Opaleye Management Inc. | 10% Owner | Nov 03 | Sale | 6.53 | 116,500 | 760,850 | 101,500 | Nov 05 04:13 PM |
| ETON | Opaleye Management Inc. | 10% Owner | Nov 04 | Sale | 6.44 | 85,700 | 551,651 | 97,500 | Nov 05 04:13 PM |
| ETON | Opaleye Management Inc. | 10% Owner | Oct 08 | Sale | 5.00 | 43,692 | 218,469 | 114,408 | Oct 13 07:57 AM |
| ETON | Opaleye Management Inc. | 10% Owner | Oct 11 | Sale | 5.01 | 34,101 | 170,716 | 112,807 | Oct 13 07:57 AM |
| ETON | Opaleye Management Inc. | 10% Owner | Oct 12 | Sale | 5.06 | 87,307 | 441,485 | 117,100 | Oct 13 07:57 AM |
| HROW | Opaleye Management Inc. | 10% Owner | Aug 19 | Buy | 8.45 | 52,500 | 443,362 | 3,135,000 | Aug 23 05:59 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Aug 17 | Buy | 8.57 | 26,000 | 222,719 | 3,040,000 | Aug 19 07:10 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Aug 18 | Buy | 8.64 | 46,500 | 401,979 | 3,085,000 | Aug 19 07:10 PM |
| ETON | Opaleye Management Inc. | 10% Owner | Aug 04 | Sale | 5.75 | 104,000 | 598,146 | 137,600 | Aug 06 09:53 PM |
| ETON | Opaleye Management Inc. | 10% Owner | Aug 05 | Sale | 5.85 | 155,500 | 910,173 | 132,100 | Aug 06 09:53 PM |
| ETON | Opaleye Management Inc. | 10% Owner | Aug 06 | Sale | 5.84 | 345,000 | 2,014,869 | 117,100 | Aug 06 09:53 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Jul 19 | Buy | 6.97 | 5,869 | 40,897 | 3,005,700 | Jul 22 09:19 AM |
| HROW | Opaleye Management Inc. | 10% Owner | Jul 20 | Buy | 7.20 | 4,925 | 35,460 | 3,010,500 | Jul 22 09:19 AM |
| HROW | Opaleye Management Inc. | 10% Owner | Jul 21 | Buy | 7.60 | 9,206 | 69,933 | 3,015,000 | Jul 22 09:19 AM |
| HROW | Opaleye Management Inc. | 10% Owner | Jun 17 | Buy | 8.32 | 11,262 | 93,701 | 2,940,200 | Jun 22 11:44 AM |
| HROW | Opaleye Management Inc. | 10% Owner | Jun 18 | Buy | 8.35 | 63,322 | 528,688 | 3,000,000 | Jun 22 11:44 AM |
| ETON | Opaleye Management Inc. | 10% Owner | Jun 15 | Sale | 8.07 | 105,000 | 847,350 | 141,600 | Jun 17 04:39 PM |
| ETON | Opaleye Management Inc. | 10% Owner | May 25 | Sale | 8.53 | 48,000 | 409,440 | 153,000 | May 27 07:34 PM |
| ETON | Opaleye Management Inc. | 10% Owner | May 26 | Sale | 8.57 | 68,300 | 585,331 | 150,200 | May 27 07:34 PM |
| ETON | Opaleye Management Inc. | 10% Owner | May 27 | Sale | 8.49 | 126,000 | 1,069,740 | 145,600 | May 27 07:34 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Dec 22 | Buy | 8.06 | 496,277 | 3,999,993 | 2,293,371 | Dec 28 09:53 AM |
| HROW | Opaleye Management Inc. | 10% Owner | Dec 18 | Buy | 5.31 | 36,400 | 193,379 | 2,862,100 | Dec 22 06:09 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Dec 21 | Buy | 5.24 | 53,459 | 280,093 | 2,913,500 | Dec 22 06:09 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Dec 22 | Buy | 5.19 | 16,557 | 86,010 | 2,929,400 | Dec 22 06:09 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Oct 21 | Buy | 4.40 | 8,656 | 38,060 | 1,797,094 | Oct 23 09:30 PM |
| ETON | Opaleye Management Inc. | 10% Owner | Oct 16 | Buy | 7.00 | 400,000 | 2,800,000 | 3,885,000 | Oct 16 09:30 PM |
| TARA | Opaleye Management Inc. | 10% Owner | Sep 30 | Buy | 16.00 | 50,000 | 800,000 | 2,458,472 | Oct 02 06:05 AM |
| TCON | Opaleye Management Inc. | 10% Owner | Sep 23 | Buy | 4.83 | 57,200 | 276,448 | 1,764,438 | Sep 25 09:30 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Sep 24 | Buy | 4.44 | 21,534 | 95,648 | 1,785,438 | Sep 25 09:30 PM |
| TARA | Opaleye Management Inc. | 10% Owner | Sep 24 | Buy | 16.87 | 300,000 | 5,061,000 | 2,408,472 | Sep 25 05:15 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Sep 04 | Buy | 2.88 | 9,058 | 26,130 | 1,664,438 | Sep 09 06:15 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Sep 09 | Buy | 3.47 | 47,500 | 164,773 | 1,709,438 | Sep 09 06:15 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Sep 01 | Buy | 2.04 | 40,000 | 81,768 | 1,540,946 | Sep 03 05:15 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Sep 02 | Buy | 2.35 | 119,800 | 282,057 | 1,655,946 | Sep 03 05:15 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Aug 27 | Buy | 1.71 | 183,354 | 312,949 | 1,206,196 | Aug 31 09:36 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Aug 28 | Buy | 1.78 | 60,000 | 106,974 | 210,000 | Aug 31 09:36 PM |
| TCON | Opaleye Management Inc. | 10% Owner | Aug 31 | Buy | 1.76 | 302,150 | 530,455 | 1,502,346 | Aug 31 09:36 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Jul 10 | Buy | 4.98 | 45,000 | 223,965 | 2,761,300 | Jul 14 09:45 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Jul 11 | Buy | 4.96 | 46,800 | 231,922 | 2,808,100 | Jul 14 09:45 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Jul 12 | Buy | 4.99 | 20,900 | 104,246 | 2,827,100 | Jul 14 09:45 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Jul 07 | Buy | 5.18 | 41,300 | 213,996 | 2,626,300 | Jul 09 09:30 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Jul 08 | Buy | 4.99 | 65,000 | 324,630 | 2,691,300 | Jul 09 09:30 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Jul 09 | Buy | 4.84 | 30,000 | 145,078 | 2,716,300 | Jul 09 09:30 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Jun 19 | Buy | 5.58 | 35,000 | 195,402 | 2,585,000 | Jun 23 09:45 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Jun 02 | Buy | 5.69 | 19,400 | 110,339 | 2,519,400 | Jun 04 06:06 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Jun 03 | Buy | 5.74 | 20,600 | 118,308 | 2,540,000 | Jun 04 06:06 PM |
| HROW | Opaleye Management Inc. | 10% Owner | Jun 04 | Buy | 5.79 | 10,000 | 57,861 | 2,550,000 | Jun 04 06:06 PM |
| HROW | Opaleye Management Inc. | 10% Owner | May 20 | Buy | 4.49 | 1,500 | 6,739 | 2,480,800 | May 22 07:22 PM |
| HROW | Opaleye Management Inc. | 10% Owner | May 21 | Buy | 4.66 | 10,596 | 49,338 | 2,491,196 | May 22 07:22 PM |
| HROW | Opaleye Management Inc. | 10% Owner | May 22 | Buy | 5.04 | 13,804 | 69,589 | 2,500,000 | May 22 07:22 PM |
| OCUL | Opaleye Management Inc. | 10% Owner | Jan 02 | Buy | 3.90 | 15,000 | 58,508 | 4,918,500 | Jan 03 07:45 PM |
| OCUL | Opaleye Management Inc. | 10% Owner | Dec 30 | Buy | 3.97 | 20,000 | 79,410 | 4,903,500 | Jan 02 05:15 PM |
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