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Last Close
Sep 06 04:00PM ET
37.19
Dollar change
-0.43
Percentage change
-1.14
%
IndexRUT P/E14.42 EPS (ttm)2.58 Insider Own2.99% Shs Outstand31.87M Perf Week-3.68%
Market Cap1.20B Forward P/E5.51 EPS next Y6.75 Insider Trans-17.33% Shs Float31.25M Perf Month7.33%
Income99.89M PEG26.21 EPS next Q1.60 Inst Own124.38% Short Float19.57% Perf Quarter18.59%
Sales576.65M P/S2.08 EPS this Y14.95% Inst Trans-1.90% Short Ratio13.09 Perf Half Y-0.03%
Book/sh6.70 P/B5.55 EPS next Y7.36% ROA8.81% Short Interest6.11M Perf Year56.85%
Cash/sh8.43 P/C4.41 EPS next 5Y0.55% ROE47.87% 52W Range20.95 - 40.95 Perf YTD20.83%
Dividend Est.- P/FCF4.35 EPS past 5Y- ROI16.88% 52W High-9.18% Beta0.94
Dividend TTM- Quick Ratio1.04 Sales past 5Y17.87% Gross Margin61.94% 52W Low77.52% ATR (14)1.26
Dividend Ex-Date- Current Ratio1.11 EPS Y/Y TTM1019.55% Oper. Margin35.32% RSI (14)54.04 Volatility3.02% 3.25%
Employees197 Debt/Eq2.58 Sales Y/Y TTM7.39% Profit Margin17.32% Recom1.80 Target Price43.25
Option/ShortYes / Yes LT Debt/Eq1.73 EPS Q/Q52.35% Payout0.00% Rel Volume0.43 Prev Close37.62
Sales Surprise0.93% EPS Surprise9.08% Sales Q/Q7.18% EarningsAug 08 AMC Avg Volume467.04K Price37.19
SMA201.72% SMA506.95% SMA2009.93% Trades Volume198,967 Change-1.14%
Date Action Analyst Rating Change Price Target Change
Jul-30-24Upgrade H.C. Wainwright Neutral → Buy $47
Jun-07-24Upgrade Jefferies Hold → Buy $41 → $44
May-10-24Downgrade Piper Sandler Overweight → Neutral $39
May-10-24Downgrade Needham Buy → Hold
Jan-04-24Downgrade Jefferies Buy → Hold $30 → $37
Aug-25-23Reiterated Needham Buy $35 → $36
May-02-23Resumed Jefferies Buy $30
Aug-08-22Downgrade H.C. Wainwright Buy → Neutral
Feb-15-22Upgrade Cantor Fitzgerald Neutral → Overweight $18 → $26
Aug-06-21Downgrade Cantor Fitzgerald Overweight → Neutral
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Collegium Pharmaceutical, Inc. is a pharmaceutical company, which engages in development and planning to commercialize next generation, abuse-deterrent products for the treatment of patients suffering from chronic pain and other diseases. Its products include Xtampza ER, Nucynta ER and Nucynta IR, Belbuca, and Symproic. The company was founded by Michael Thomas Heffernan in April 2002 and is headquartered in Stoughton, MA.
Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total SEC Form 4
Kuhlmann Shirley R.EVP and General CounselSep 05 '24Sale38.3019,248737,198120,161Sep 06 05:52 PM
Kuhlmann Shirley R.EVP and General CounselSep 06 '24Sale37.4697736,594119,184Sep 06 05:52 PM
Kuhlmann Shirley R.OfficerSep 06 '24Proposed Sale37.4697736,594Sep 06 11:53 AM
Kuhlmann Shirley R.OfficerSep 05 '24Proposed Sale38.3019,248737,197Sep 05 04:47 PM
McFarlane Neil F.Former DirectorAug 12 '24Proposed Sale35.2144,3651,562,312Aug 12 02:41 PM
McFarlane Neil F.Former DirectorAug 09 '24Proposed Sale35.205,000176,007Aug 09 04:34 PM
Kuhlmann Shirley R.EVP and General CounselJun 03 '24Sale32.5725,000814,180139,409Jun 05 04:06 PM
Tupper ColleenEVP & Chief Financial OfficerMay 28 '24Sale34.2119,710674,368130,845May 29 04:29 PM
Dreyer ScottEVP & Chief Commercial OfficerMay 23 '24Option Exercise24.0351,2091,230,552190,127May 28 04:22 PM
Dreyer ScottEVP & Chief Commercial OfficerMay 24 '24Option Exercise24.0323,791571,698162,709May 28 04:22 PM
Dreyer ScottEVP & Chief Commercial OfficerMay 24 '24Sale33.9856,8071,930,455105,902May 28 04:22 PM
Dreyer ScottEVP & Chief Commercial OfficerMay 23 '24Sale33.8251,2091,732,093138,918May 28 04:22 PM
BOHLIN GAREN GDirectorMay 14 '24Option Exercise5.7328,985166,08473,760May 16 07:20 PM
BOHLIN GAREN GDirectorMay 14 '24Sale32.3028,985936,31144,775May 16 07:20 PM
Smith Thomas BEVP and Chief Medical OfficerFeb 29 '24Sale36.7699536,58063,409Mar 04 04:26 PM
Dreyer ScottEVP & Chief Commercial OfficerFeb 26 '24Sale36.4310,000364,270138,918Feb 28 04:14 PM
Dreyer ScottEVP & Chief Commercial OfficerJan 16 '24Sale32.2823,560760,519111,322Jan 18 04:19 PM
Ciaffoni JosephPresident and CEODec 21 '23Option Exercise21.344,35792,978279,357Dec 22 04:36 PM
Ciaffoni JosephPresident and CEODec 21 '23Sale30.384,357132,377275,000Dec 22 04:36 PM
Ciaffoni JosephPresident and CEODec 18 '23Option Exercise21.3427,798593,209302,798Dec 20 05:51 PM
Ciaffoni JosephPresident and CEODec 20 '23Option Exercise21.3426,454564,528301,454Dec 20 05:51 PM
Ciaffoni JosephPresident and CEODec 19 '23Option Exercise21.3414,516309,771289,516Dec 20 05:51 PM
Ciaffoni JosephPresident and CEODec 18 '23Sale30.0427,798834,935275,000Dec 20 05:51 PM
Ciaffoni JosephPresident and CEODec 20 '23Sale30.4026,454804,210275,000Dec 20 05:51 PM
Ciaffoni JosephPresident and CEODec 19 '23Sale30.0314,516435,942275,000Dec 20 05:51 PM
Kuhlmann Shirley R.EVP and General CounselNov 27 '23Option Exercise15.9025,600407,040145,118Nov 29 04:32 PM
Kuhlmann Shirley R.EVP and General CounselNov 27 '23Sale25.7825,600660,014119,518Nov 29 04:32 PM
Last Close
Sep 06 04:00PM ET
0.7302
Dollar change
-0.0675
Percentage change
-8.46
%
KPTI Karyopharm Therapeutics Inc daily Stock Chart
Index- P/E- EPS (ttm)-1.19 Insider Own8.37% Shs Outstand114.92M Perf Week-5.27%
Market Cap91.04M Forward P/E- EPS next Y-0.67 Insider Trans-14.52% Shs Float114.24M Perf Month-9.99%
Income-89.91M PEG- EPS next Q-0.26 Inst Own54.21% Short Float15.98% Perf Quarter-24.95%
Sales145.67M P/S0.62 EPS this Y40.91% Inst Trans-0.04% Short Ratio16.84 Perf Half Y-52.27%
Book/sh-1.06 P/B- EPS next Y9.09% ROA-35.14% Short Interest18.26M Perf Year-37.59%
Cash/sh1.22 P/C0.60 EPS next 5Y- ROE- 52W Range0.62 - 1.95 Perf YTD-15.58%
Dividend Est.- P/FCF- EPS past 5Y16.79% ROI-149.99% 52W High-62.55% Beta0.17
Dividend TTM- Quick Ratio3.56 Sales past 5Y52.21% Gross Margin95.81% 52W Low18.27% ATR (14)0.06
Dividend Ex-Date- Current Ratio3.62 EPS Y/Y TTM45.95% Oper. Margin-89.89% RSI (14)39.68 Volatility9.16% 6.29%
Employees325 Debt/Eq- Sales Y/Y TTM-0.23% Profit Margin-61.72% Recom1.57 Target Price4.36
Option/ShortYes / Yes LT Debt/Eq- EPS Q/Q30.63% Payout- Rel Volume0.46 Prev Close0.80
Sales Surprise18.16% EPS Surprise32.86% Sales Q/Q13.86% EarningsAug 06 BMO Avg Volume1.08M Price0.73
SMA20-8.46% SMA50-15.77% SMA200-28.52% Trades Volume494,583 Change-8.46%
Date Action Analyst Rating Change Price Target Change
Jan-19-23Initiated Piper Sandler Overweight $8
Nov-04-22Upgrade RBC Capital Mkts Sector Perform → Outperform $7 → $10
Feb-09-22Upgrade JP Morgan Underweight → Neutral $8
Nov-19-21Resumed Morgan Stanley Equal-Weight $27 → $10
Aug-06-21Downgrade SVB Leerink Outperform → Mkt Perform $6
Aug-06-21Downgrade RBC Capital Mkts Outperform → Sector Perform $17 → $8
Aug-06-21Downgrade JP Morgan Overweight → Neutral
Jul-02-20Initiated Morgan Stanley Overweight $34
Mar-04-20Initiated Barclays Overweight $30
Jan-17-20Downgrade Wedbush Outperform → Neutral
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Karyopharm Therapeutics, Inc. is a commercial-stage pharmaceutical company, which engages in the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. Its Selective Inhibitor of Nuclear Export (SINE) compounds function by binding with and inhibiting the nuclear export protein XPO1 (or CRM1). Karyopharm's compound, XPOVIO (selinexor), is approved in the U.S. in multiple hematologic malignancy indications, including in combination with Velcade (bortezomib) and dexamethasone for the treatment of adult patients with multiple myeloma after at least one prior therapy, in combination with dexamethasone for the treatment of adult patients with pretreated multiple myeloma and as a monotherapy for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. In addition to single-agent and combination activity against a variety of human cancers, SINE compounds have also shown biological activity in models of neurodegeneration, inflammation, autoimmune disease, certain viruses, and wound-healing. Karyopharm has several investigational programs in clinical or preclinical development. The company was founded by Joseph Araujo, Ronald A. DePinho, Pamela A, Silver, Giulio Draetta, Michael G. Kauffman, and Sharon Shacham on December 22, 2008 and is headquartered in Newton, MA.
Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total SEC Form 4
Mano MichaelSVP, General Counsel&SecretarySep 04 '24Sale0.723,9712,866273,881Sep 05 04:28 PM
Paulson Richard A.President and CEOSep 04 '24Sale0.723,6672,6471,139,214Sep 05 04:26 PM
Mason MichaelEVP, CFO & TreasurerSep 04 '24Sale0.727,0505,089391,054Sep 05 04:24 PM
Cheng Sohanya RoshanEVP & Chief Commercial OfficerSep 04 '24Sale0.725,3563,866404,051Sep 05 04:13 PM
Paulson Richard A.President and CEOAug 06 '24Sale0.933,6083,3551,142,881Aug 08 04:31 PM
Poulton StuartEVP, Chief Development OfficerJul 30 '24Sale1.062,8833,056326,628Jul 31 04:14 PM
Paulson Richard A.President and CEOJul 05 '24Sale0.853,6163,0771,146,489Jul 09 04:15 PM
PAKIANATHAN DEEPIKADirectorJun 05 '24Sale0.96468,044448,4803,385Jun 07 07:18 PM
PAKIANATHAN DEEPIKADirectorJun 07 '24Sale0.95231,548220,1330Jun 07 07:18 PM
PAKIANATHAN DEEPIKADirectorJun 06 '24Sale0.98118,452116,4152,240Jun 07 07:18 PM
Mason MichaelEVP, CFO & TreasurerJun 04 '24Sale0.99652645398,104Jun 06 04:03 PM
Paulson Richard A.President and CEOJun 04 '24Sale0.993,5923,5561,150,105Jun 06 04:02 PM
PAKIANATHAN DEEPIKADirectorJun 03 '24Sale1.00360,744360,99711,209Jun 04 06:51 PM
PAKIANATHAN DEEPIKADirectorJun 04 '24Sale0.95341,040324,7047,911Jun 04 06:51 PM
PAKIANATHAN DEEPIKADirectorMay 31 '24Sale0.95204,394194,99214,697Jun 04 06:51 PM
Paulson Richard A.President and CEOMay 06 '24Sale1.133,5764,0411,153,697May 07 04:56 PM
Rangwala ReshmaEVP & Chief Medical OfficerApr 22 '24Sale1.176,7897,943342,931Apr 23 04:02 PM
Paulson Richard A.President and CEOApr 04 '24Sale1.293,5634,5961,157,273Apr 05 05:20 PM
Paulson Richard A.President and CEOMar 05 '24Sale1.303,5734,6451,160,836Mar 06 04:14 PM
Rangwala ReshmaEVP & Chief Medical OfficerFeb 29 '24Sale1.1715,66718,330355,689Mar 04 07:41 PM
Rangwala ReshmaEVP & Chief Medical OfficerMar 01 '24Sale1.205,9697,163349,720Mar 04 07:41 PM
Poulton StuartEVP, Chief Development OfficerFeb 29 '24Sale1.1716,31119,084335,666Mar 04 07:40 PM
Poulton StuartEVP, Chief Development OfficerMar 01 '24Sale1.206,1557,386329,511Mar 04 07:40 PM
Mason MichaelEVP, CFO & TreasurerFeb 29 '24Sale1.1727,68732,394404,918Mar 04 07:39 PM
Mason MichaelEVP, CFO & TreasurerMar 01 '24Sale1.206,1627,394398,756Mar 04 07:39 PM
Mano MichaelSVP, General Counsel&SecretaryFeb 29 '24Sale1.1716,97319,858281,428Mar 04 07:38 PM
Mano MichaelSVP, General Counsel&SecretaryMar 01 '24Sale1.203,5764,291277,852Mar 04 07:38 PM
Cheng Sohanya RoshanEVP & Chief Commercial OfficerFeb 29 '24Sale1.1721,84025,553398,618Mar 04 07:37 PM
Cheng Sohanya RoshanEVP & Chief Commercial OfficerMar 01 '24Sale1.205,1096,131393,509Mar 04 07:37 PM
Paulson Richard A.President and CEOFeb 29 '24Sale1.1780,47094,1501,183,783Mar 04 07:36 PM
Paulson Richard A.President and CEOMar 01 '24Sale1.2019,37423,2491,164,409Mar 04 07:36 PM
Mason MichaelEVP, CFO & TreasurerFeb 27 '24Sale1.322,5453,369244,400Feb 29 05:35 PM
Poulton StuartEVP, Chief Development OfficerFeb 15 '24Sale1.335,8477,783163,772Feb 20 04:59 PM
Mason MichaelEVP, CFO & TreasurerFeb 06 '24Sale1.594,2056,671246,945Feb 08 04:36 PM
Paulson Richard A.President and CEOFeb 06 '24Sale1.594,0126,365821,453Feb 08 04:34 PM
Paulson Richard A.President and CEOJan 04 '24Sale0.824,1143,373783,465Jan 08 09:00 PM
Paulson Richard A.President and CEODec 04 '23Sale0.793,6222,861787,579Dec 05 05:03 PM
Paulson Richard A.President and CEONov 06 '23Sale0.923,6063,319791,201Nov 07 05:32 PM
Paulson Richard A.President and CEOOct 04 '23Sale1.273,5894,558794,807Oct 05 04:46 PM
BOHLIN GAREN GDirectorSep 12 '23Buy1.2241,14049,98545,140Sep 12 04:07 PM