Index RUT
P/E -
EPS (ttm) -2.76
Insider Own 13.45%
Shs Outstand 138.39M
Perf Week -1.44%
Market Cap 3.62B
Forward P/E -
EPS next Y -2.86
Insider Trans -1.14%
Shs Float 124.57M
Perf Month -6.62%
Income -427.49M
PEG -
EPS next Q -0.81
Inst Own 88.60%
Short Float 5.96%
Perf Quarter -3.55%
Sales 0.00M
P/S -
EPS this Y -162.14%
Inst Trans 6.24%
Short Ratio 8.53
Perf Half Y 28.53%
Book/sh 9.17
P/B 2.69
EPS next Y -2.97%
ROA -31.77%
Short Interest 7.43M
Perf Year 36.41%
Cash/sh 5.70
P/C 4.33
EPS next 5Y -
ROE -35.09%
52W Range 14.56 - 33.33
Perf YTD 15.05%
Dividend Est. -
P/FCF -
EPS past 5Y -21.99%
ROI -31.36%
52W High -25.92%
Beta 1.36
Dividend TTM -
Quick Ratio 9.98
Sales past 5Y 264.19%
Gross Margin -570.72%
52W Low 69.57%
ATR (14) 1.41
Dividend Ex-Date -
Current Ratio 9.98
EPS Y/Y TTM -197.15%
Oper. Margin 0.00%
RSI (14) 38.85
Volatility 4.10% 5.41%
Employees 445
Debt/Eq 0.04
Sales Y/Y TTM -100.00%
Profit Margin -
Recom 1.35
Target Price 41.69
Option/Short Yes / Yes
LT Debt/Eq 0.03
EPS Q/Q 12.36%
Payout -
Rel Volume 0.95
Prev Close 24.22
Sales Surprise -100.00%
EPS Surprise -5.86%
Sales Q/Q -100.00%
Earnings Nov 06 AMC
Avg Volume 870.42K
Price 24.69
SMA20 -9.71%
SMA50 -11.43%
SMA200 9.17%
Trades
Volume 830,354
Change 1.94%
Date
Action
Analyst
Rating Change
Price Target Change
Oct-10-24 Resumed
Raymond James
Mkt Perform
Oct-07-24 Downgrade
Cantor Fitzgerald
Overweight → Neutral
Dec-13-23 Initiated
Citigroup
Buy
$32
Nov-20-23 Resumed
JP Morgan
Overweight
$28
Oct-24-23 Resumed
Cantor Fitzgerald
Overweight
$85 → $35
Sep-06-23 Initiated
B. Riley Securities
Buy
$38
Jan-30-23 Initiated
SVB Securities
Outperform
$50
Dec-05-22 Initiated
Cowen
Outperform
Nov-02-22 Upgrade
BTIG Research
Neutral → Buy
$38
Nov-02-22 Initiated
BofA Securities
Buy
$40
Jun-23-22 Initiated
Berenberg
Buy
$39
Dec-10-21 Resumed
Raymond James
Mkt Perform
Sep-21-21 Initiated
Oppenheimer
Outperform
$85
Sep-01-21 Initiated
SMBC Nikko
Outperform
$78
May-18-21 Initiated
UBS
Buy
$70
Feb-26-21 Reiterated
H.C. Wainwright
Buy
$80 → $95
Feb-10-21 Upgrade
Cantor Fitzgerald
Neutral → Overweight
$105
Nov-11-20 Reiterated
H.C. Wainwright
Buy
$65 → $80
Oct-16-20 Downgrade
BTIG Research
Buy → Neutral
Sep-14-20 Resumed
JP Morgan
Overweight
$35
Show Previous Ratings
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(The Wall Street Journal)
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Denali Therapeutics, Inc. is a biopharmaceutical company, which engages in the development and commercialization of a portfolio of product candidates for neurodegenerative diseases. Its product pipeline includes LRRK2, RIPK1, TREM2, and Tau. The company was founded by Ryan J. Watts, Marc Tessier-Lavigne, and Alexander Schuth on October 14, 2013 and is headquartered in San Francisco, CA.
Insider Trading
Relationship
Date
Transaction
Cost
#Shares
Value ($)
#Shares Total
SEC Form 4
Schenkein David P Director Nov 11 '24 Option Exercise 18.00 47,165 848,970 68,661 Nov 13 04:18 PM Schenkein David P Director Nov 11 '24 Sale 32.51 59,441 1,932,665 9,220 Nov 13 04:18 PM Schuth Alexander O. COFO and Secretary Nov 07 '24 Option Exercise 5.28 15,558 82,146 193,624 Nov 12 04:44 PM Schuth Alexander O. COFO and Secretary Nov 07 '24 Sale 29.91 15,558 465,286 178,066 Nov 12 04:44 PM SATO VICKI L Director Nov 07 '24 Sale 30.00 1,020 30,600 111,056 Nov 12 04:43 PM DAVID SCHENKEIN Director Nov 11 '24 Proposed Sale 31.35 59,441 1,863,475 Nov 12 07:47 AM ALEXANDER SCHUTH Officer Nov 07 '24 Proposed Sale 29.55 15,558 459,739 Nov 07 04:39 PM SATO VICKI L Director Nov 01 '24 Sale 27.07 3,080 83,376 112,076 Nov 05 04:21 PM Watts Ryan J. President and CEO Oct 18 '24 Option Exercise 0.68 40,000 27,200 275,807 Oct 22 04:30 PM Watts Ryan J. President and CEO Oct 18 '24 Sale 27.69 40,000 1,107,600 235,807 Oct 22 04:30 PM RYAN WATTS Director Oct 18 '24 Proposed Sale 27.42 40,000 1,096,800 Oct 18 04:19 PM Krognes Steve E. Director Sep 30 '24 Sale 29.03 30,000 870,900 29,096 Oct 02 04:37 PM STEVE KROGNES Director Sep 30 '24 Proposed Sale 29.43 30,000 882,900 Sep 30 04:25 PM SATO VICKI L Director Sep 13 '24 Sale 30.00 1,020 30,600 115,156 Sep 16 04:17 PM VICKI LEE SATO Director Sep 13 '24 Proposed Sale 27.96 6,160 172,234 Sep 13 04:25 PM SATO VICKI L Director Sep 03 '24 Sale 25.00 3,080 77,007 116,176 Sep 04 06:26 PM Watts Ryan J. President and CEO Aug 20 '24 Sale 23.79 2,260 53,765 235,807 Aug 22 04:16 PM Krognes Steve E. Director Aug 20 '24 Sale 23.79 1,727 41,085 32,677 Aug 22 04:15 PM Schuth Alexander O. COFO and Secretary Aug 20 '24 Sale 23.65 5,806 137,286 180,613 Aug 22 04:14 PM Schuth Alexander O. COFO and Secretary Aug 21 '24 Sale 24.78 2,547 63,115 178,066 Aug 22 04:14 PM Ho Carole Chief Medical Officer Aug 21 '24 Sale 24.57 20,005 491,571 118,810 Aug 22 04:14 PM Ho Carole Chief Medical Officer Aug 20 '24 Sale 23.79 2,453 58,357 138,815 Aug 22 04:14 PM CAROLE HO Officer Aug 21 '24 Proposed Sale 23.65 20,005 473,118 Aug 21 04:42 PM ALEXANDER SCHUTH Officer Aug 21 '24 Proposed Sale 23.65 2,547 60,237 Aug 21 04:40 PM Krognes Steve E. Director Aug 20 '24 Proposed Sale 23.79 1,727 41,085 Aug 20 08:09 PM Schuth Alexander O. Officer Aug 20 '24 Proposed Sale 23.79 2,453 58,357 Aug 20 08:09 PM Watts Ryan J. Director Aug 20 '24 Proposed Sale 23.79 2,260 53,765 Aug 20 08:08 PM Ho Carole Officer Aug 20 '24 Proposed Sale 23.79 2,453 58,356 Aug 20 08:08 PM ALEXANDER SCHUTH Officer Aug 20 '24 Proposed Sale 23.95 3,353 80,304 Aug 20 04:27 PM Schuth Alexander O. COFO and Secretary Aug 13 '24 Sale 22.89 2,272 52,006 186,419 Aug 15 04:10 PM Ho Carole Chief Medical Officer Aug 13 '24 Sale 22.89 2,337 53,494 141,268 Aug 15 04:09 PM Schuth Alexander O. Officer Aug 13 '24 Proposed Sale 22.89 2,272 52,006 Aug 13 08:37 PM Ho Carole Officer Aug 13 '24 Proposed Sale 22.89 2,337 53,494 Aug 13 08:36 PM Krognes Steve E. Director Jul 01 '24 Sale 22.12 30,000 663,668 34,404 Jul 03 09:13 PM Krognes Steve E. Director Jun 13 '24 Sale 21.79 688 14,992 52,620 Jul 03 09:13 PM SATO VICKI L Director Jul 01 '24 Sale 22.14 3,080 68,204 119,256 Jul 03 09:13 PM Cook Jennifer E. Director Jun 06 '24 Sale 21.73 1,458 31,682 20,038 Jun 10 08:06 PM SATO VICKI L Director May 15 '24 Sale 20.39 1,674 34,133 116,369 May 17 04:28 PM SATO VICKI L Director Apr 15 '24 Sale 18.29 1,666 30,471 118,043 Apr 17 05:14 PM Krognes Steve E. Director Apr 01 '24 Sale 20.50 92,500 1,896,250 47,341 Apr 02 06:07 PM SATO VICKI L Director Mar 15 '24 Sale 20.10 1,666 33,487 119,709 Mar 19 04:27 PM SATO VICKI L Director Feb 15 '24 Sale 18.37 1,666 30,604 121,375 Feb 20 05:38 PM Krognes Steve E. Director Feb 13 '24 Sale 17.29 2,750 47,548 139,841 Feb 15 09:16 PM Watts Ryan J. President and CEO Feb 13 '24 Sale 17.29 9,589 165,794 238,067 Feb 15 09:15 PM Ho Carole Chief Medical Officer Feb 13 '24 Sale 17.29 2,784 48,135 145,010 Feb 15 09:14 PM Ho Carole Chief Medical Officer Feb 14 '24 Sale 17.79 1,405 24,995 143,605 Feb 15 09:14 PM Schuth Alexander O. COFO and Secretary Feb 14 '24 Sale 17.66 20,128 355,460 187,341 Feb 15 09:14 PM Schuth Alexander O. COFO and Secretary Feb 13 '24 Sale 17.29 2,716 46,960 207,469 Feb 15 09:14 PM Schuth Alexander O. COFO and Secretary Feb 08 '24 Option Exercise 0.68 50,000 34,000 210,185 Feb 12 04:48 PM SATO VICKI L Director Jan 16 '24 Sale 18.42 1,666 30,688 123,041 Jan 18 06:26 PM Ho Carole Chief Medical Officer Jan 10 '24 Sale 19.02 4,668 88,785 147,794 Jan 12 08:18 PM Watts Ryan J. President and CEO Jan 09 '24 Sale 19.78 7,818 154,640 2,268,363 Jan 11 05:28 PM Ho Carole Chief Medical Officer Jan 05 '24 Sale 19.43 9,972 193,756 198,777 Jan 09 07:35 PM Krognes Steve E. Director Jan 05 '24 Sale 19.43 3,208 62,331 142,591 Jan 09 07:34 PM Schuth Alexander O. COFO and Secretary Jan 05 '24 Sale 19.43 9,972 193,756 539,307 Jan 09 07:34 PM Watts Ryan J. President and CEO Jan 05 '24 Sale 19.43 17,483 339,695 2,276,181 Jan 09 07:33 PM SATO VICKI L Director Dec 15 '23 Sale 23.39 1,666 38,968 124,707 Dec 18 07:30 PM
Index RUT
P/E 4.90
EPS (ttm) 11.37
Insider Own 3.32%
Shs Outstand 55.95M
Perf Week 3.53%
Market Cap 3.18B
Forward P/E -
EPS next Y -6.08
Insider Trans -3.72%
Shs Float 55.13M
Perf Month 23.51%
Income 674.31M
PEG -
EPS next Q -1.68
Inst Own 104.87%
Short Float 7.87%
Perf Quarter 19.56%
Sales 32.87M
P/S 96.85
EPS this Y 281.41%
Inst Trans 3.19%
Short Ratio 7.76
Perf Half Y 76.76%
Book/sh 28.53
P/B 1.95
EPS next Y -152.92%
ROA 48.18%
Short Interest 4.34M
Perf Year 153.55%
Cash/sh 17.57
P/C 3.17
EPS next 5Y -
ROE 53.65%
52W Range 20.96 - 62.58
Perf YTD 150.02%
Dividend Est. -
P/FCF -
EPS past 5Y -0.98%
ROI 40.35%
52W High -11.03%
Beta 0.76
Dividend TTM -
Quick Ratio 8.77
Sales past 5Y 2.66%
Gross Margin 72.07%
52W Low 165.65%
ATR (14) 2.40
Dividend Ex-Date -
Current Ratio 8.99
EPS Y/Y TTM 398.86%
Oper. Margin -1238.10%
RSI (14) 62.44
Volatility 3.90% 4.81%
Employees 383
Debt/Eq 0.04
Sales Y/Y TTM 36.79%
Profit Margin 2051.38%
Recom 1.70
Target Price 53.88
Option/Short Yes / Yes
LT Debt/Eq 0.03
EPS Q/Q 1091.28%
Payout -
Rel Volume 0.82
Prev Close 55.54
Sales Surprise -4.64%
EPS Surprise 6.60%
Sales Q/Q 21.15%
Earnings Oct 31 BMO
Avg Volume 559.18K
Price 55.68
SMA20 6.45%
SMA50 17.42%
SMA200 38.26%
Trades
Volume 456,102
Change 0.25%
Date
Action
Analyst
Rating Change
Price Target Change
Oct-16-24 Initiated
Scotiabank
Sector Outperform
Oct-10-24 Resumed
Raymond James
Outperform
$51
Sep-27-24 Downgrade
Leerink Partners
Outperform → Market Perform
$60 → $56
Feb-08-24 Initiated
Cantor Fitzgerald
Overweight
Feb-03-23 Initiated
Piper Sandler
Overweight
$41
Nov-17-22 Upgrade
Goldman
Sell → Neutral
$17 → $32
Jul-27-22 Upgrade
SVB Leerink
Mkt Perform → Outperform
$33
Dec-03-21 Initiated
BofA Securities
Buy
$54
Jul-30-21 Downgrade
Goldman
Neutral → Sell
$58 → $39
Jul-01-21 Initiated
Raymond James
Mkt Perform
Jun-10-21 Initiated
H.C. Wainwright
Buy
$88
Mar-01-21 Upgrade
SVB Leerink
Mkt Perform → Outperform
$50
Mar-01-21 Downgrade
JP Morgan
Overweight → Neutral
$64 → $54
Feb-26-21 Downgrade
SVB Leerink
Outperform → Mkt Perform
Oct-22-20 Upgrade
Barclays
Equal Weight → Overweight
$46
Mar-04-20 Initiated
Barclays
Equal Weight
$50
Nov-26-19 Initiated
Cantor Fitzgerald
Overweight
$64
Sep-23-19 Upgrade
Guggenheim
Neutral → Buy
$55
May-23-19 Resumed
Goldman
Neutral
$55
Feb-15-19 Upgrade
SVB Leerink
Mkt Perform → Outperform
$80
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(Associated Press Finance)
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(Investor's Business Daily) +23.21%
12:20PM
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09:46AM
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(Investor's Business Daily)
Feb-23-24 10:45AM
(Investor's Business Daily) +10.78%
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(Thomson Reuters StreetEvents)
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Jan-03-24 04:05PM
(Investor's Business Daily) +5.21%
02:46PM
(The Wall Street Journal)
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10:09AM
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09:26AM
(Investor's Business Daily)
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(American City Business Journals)
Aug-04-23 05:32PM
09:10AM
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Aug-03-23 11:53PM
(Thomson Reuters StreetEvents)
Agios Pharmaceuticals, Inc. is a biopharmaceutical company, which engages in a research engine, multiple novels, and investigational therapies in preclinical development. It focuses on cellular metabolism and classical hematology. The company was founded by Lewis Clayton Cantley, Tak W. Mak, Craig B. Thompson and Shin-Shan Michael Su on August 7, 2007 and is headquartered in Cambridge, MA.
Insider Trading
Relationship
Date
Transaction
Cost
#Shares
Value ($)
#Shares Total
SEC Form 4
Washburn Theodore James Jr. Principal Accounting Officer Nov 08 '24 Sale 56.09 772 43,301 813 Nov 13 04:14 PM Ballal Rahul D. Director Nov 07 '24 Option Exercise 25.99 10,000 259,900 17,992 Nov 12 04:09 PM Ballal Rahul D. Director Nov 08 '24 Option Exercise 25.99 10,000 259,900 17,992 Nov 12 04:09 PM Ballal Rahul D. Director Nov 08 '24 Sale 58.19 10,000 581,911 7,992 Nov 12 04:09 PM Ballal Rahul D. Director Nov 07 '24 Sale 53.52 10,000 535,236 7,992 Nov 12 04:09 PM Burns James William Chief Legal Officer Nov 07 '24 Sale 52.21 21,752 1,135,775 15,700 Nov 12 04:08 PM RAHUL BALLAL Director Nov 08 '24 Proposed Sale 58.19 10,000 581,894 Nov 08 04:17 PM RAHUL BALLAL Director Nov 07 '24 Proposed Sale 53.52 10,000 535,241 Nov 07 04:51 PM JAMES BURNS Officer Nov 07 '24 Proposed Sale 52.21 21,752 1,135,711 Nov 07 04:06 PM Jones Cecilia Chief Financial Officer Sep 26 '24 Option Exercise 0.00 7,473 0 22,700 Sep 30 04:15 PM Jones Cecilia Chief Financial Officer Sep 26 '24 Sale 49.03 2,542 124,634 20,158 Sep 30 04:15 PM Ballal Rahul D. Director Aug 11 '24 Option Exercise 0.00 2,302 0 7,992 Aug 13 04:15 PM Smith Cynthia Director Aug 11 '24 Option Exercise 0.00 2,302 0 7,992 Aug 13 04:12 PM Goff Brian Chief Executive Officer Aug 08 '24 Option Exercise 0.00 22,691 0 89,883 Aug 12 05:15 PM Goff Brian Chief Executive Officer Aug 08 '24 Sale 42.75 11,091 474,140 78,792 Aug 12 05:15 PM Goff Brian Officer Aug 08 '24 Proposed Sale 42.75 11,091 474,184 Aug 08 04:08 PM Gheuens Sarah Chief Medical Officer Jul 01 '24 Option Exercise 0.00 8,375 0 47,441 Jul 03 04:30 PM Gheuens Sarah Chief Medical Officer Jul 01 '24 Sale 43.85 3,705 162,464 43,736 Jul 03 04:30 PM Foster-Cheek Kaye I Director Jun 13 '24 Option Exercise 0.00 3,388 0 8,912 Jun 17 05:32 PM FOUSE JACQUALYN A Director Jun 13 '24 Option Exercise 0.00 3,388 0 140,784 Jun 17 05:31 PM Schenkein David P Director Jun 13 '24 Option Exercise 0.00 3,388 0 126,242 Jun 17 05:29 PM Ballal Rahul D. Director Jun 13 '24 Option Exercise 0.00 3,388 0 5,690 Jun 17 05:22 PM Smith Cynthia Director Jun 13 '24 Option Exercise 0.00 3,388 0 5,690 Jun 17 05:20 PM Ho Maykin Director Jun 13 '24 Option Exercise 0.00 3,388 0 14,912 Jun 17 05:19 PM Scadden David Director Jun 13 '24 Option Exercise 0.00 3,388 0 15,483 Jun 17 05:18 PM Owen Catherine E. Director Jun 13 '24 Option Exercise 0.00 1,976 0 1,976 Jun 17 05:15 PM CAPELLO JEFFREY D Director Jun 13 '24 Option Exercise 0.00 1,976 0 1,976 Jun 17 05:13 PM Goff Brian Chief Executive Officer Jun 05 '24 Option Exercise 0.00 25,527 0 79,307 Jun 07 04:25 PM Goff Brian Chief Executive Officer Jun 05 '24 Sale 48.84 12,115 591,697 67,192 Jun 07 04:25 PM Washburn Theodore James Jr. Principal Accounting Officer Jun 03 '24 Sale 44.39 1,362 60,459 1,524 Jun 05 04:14 PM FOUSE JACQUALYN A Director Apr 08 '24 Option Exercise 0.00 15,934 0 145,187 Apr 10 04:03 PM FOUSE JACQUALYN A Director Apr 10 '24 Sale 27.55 7,791 214,642 137,396 Apr 10 04:03 PM Foster-Cheek Kaye I Director Mar 07 '24 Sale 31.62 1,285 40,632 5,524 Mar 11 04:09 PM Foster-Cheek Kaye I Director Mar 06 '24 Sale 31.99 4,415 141,236 6,809 Mar 07 06:49 PM Foster-Cheek Kaye I Director Mar 05 '24 Sale 32.21 300 9,663 11,224 Mar 07 06:49 PM Washburn Theodore James Jr. Principal Accounting Officer Mar 05 '24 Sale 31.75 1,913 60,738 2,886 Mar 07 06:47 PM Gheuens Sarah Chief Medical Officer Mar 01 '24 Option Exercise 0.00 7,834 0 40,415 Mar 05 04:20 PM Gheuens Sarah Chief Medical Officer Mar 05 '24 Sale 32.57 2,642 86,050 36,415 Mar 05 04:20 PM Jones Cecilia Chief Financial Officer Mar 01 '24 Option Exercise 0.00 2,000 0 15,512 Mar 05 04:18 PM Jones Cecilia Chief Financial Officer Mar 05 '24 Sale 32.57 672 21,887 14,840 Mar 05 04:18 PM Washburn Theodore James Jr. Principal Accounting Officer Mar 01 '24 Option Exercise 0.00 3,127 0 5,718 Mar 05 04:15 PM Washburn Theodore James Jr. Principal Accounting Officer Mar 05 '24 Sale 32.57 1,214 39,540 3,368 Mar 05 04:15 PM Goff Brian Chief Executive Officer Mar 01 '24 Option Exercise 0.00 8,500 0 57,936 Mar 05 04:10 PM Goff Brian Chief Executive Officer Mar 05 '24 Sale 32.57 4,156 135,361 53,780 Mar 05 04:10 PM Burns James William Chief Legal Officer Mar 01 '24 Option Exercise 0.00 7,834 0 38,518 Mar 05 04:08 PM Burns James William Chief Legal Officer Mar 05 '24 Sale 32.57 2,642 86,050 34,518 Mar 05 04:08 PM Schenkein David P Director Feb 27 '24 Option Exercise 31.64 69,329 2,193,570 180,325 Feb 29 04:05 PM Schenkein David P Director Feb 27 '24 Sale 34.67 69,329 2,403,592 122,854 Feb 29 04:05 PM Schenkein David P Director Feb 23 '24 Option Exercise 31.64 47,731 1,510,209 170,585 Feb 27 04:04 PM Schenkein David P Director Feb 26 '24 Option Exercise 31.64 20,411 645,804 143,265 Feb 27 04:04 PM Schenkein David P Director Feb 23 '24 Sale 33.05 47,731 1,577,510 122,854 Feb 27 04:04 PM Schenkein David P Director Feb 26 '24 Sale 33.19 20,411 677,441 122,854 Feb 27 04:04 PM Washburn Theodore James Jr. Principal Accounting Officer Feb 20 '24 Sale 26.63 504 13,422 2,741 Feb 22 05:43 PM Gheuens Sarah Chief Medical Officer Feb 12 '24 Option Exercise 0.00 2,162 0 34,073 Feb 14 05:53 PM Gheuens Sarah Chief Medical Officer Feb 14 '24 Sale 25.14 642 16,140 33,431 Feb 14 05:53 PM Burns James William Chief Legal Officer Feb 12 '24 Option Exercise 0.00 1,833 0 32,211 Feb 14 05:51 PM Burns James William Chief Legal Officer Feb 14 '24 Sale 25.14 545 13,701 31,666 Feb 14 05:51 PM Washburn Theodore James Jr. Principal Accounting Officer Feb 12 '24 Option Exercise 0.00 777 0 3,518 Feb 14 05:50 PM Washburn Theodore James Jr. Principal Accounting Officer Feb 14 '24 Sale 25.14 273 6,863 3,245 Feb 14 05:50 PM Burns James William Chief Legal Officer Jan 20 '24 Option Exercise 0.00 5,750 0 32,086 Jan 24 04:25 PM Burns James William Chief Legal Officer Jan 24 '24 Sale 21.64 1,708 36,961 30,378 Jan 24 04:25 PM Gheuens Sarah Chief Medical Officer Jan 20 '24 Option Exercise 0.00 5,750 0 33,619 Jan 24 04:24 PM Gheuens Sarah Chief Medical Officer Jan 24 '24 Sale 21.64 1,708 36,961 31,911 Jan 24 04:24 PM Jones Cecilia Chief Financial Officer Jan 20 '24 Option Exercise 0.00 5,380 0 14,955 Jan 24 04:23 PM Jones Cecilia Chief Financial Officer Jan 24 '24 Sale 21.64 1,886 40,813 13,069 Jan 24 04:23 PM FOUSE JACQUALYN A Director Jan 20 '24 Option Exercise 0.00 23,900 0 139,975 Jan 24 04:22 PM FOUSE JACQUALYN A Director Jan 24 '24 Sale 21.64 10,722 232,024 129,253 Jan 24 04:22 PM Goff Brian Chief Executive Officer Jan 20 '24 Option Exercise 0.00 17,018 0 57,071 Jan 24 04:20 PM Goff Brian Chief Executive Officer Jan 24 '24 Sale 21.64 7,635 165,221 49,436 Jan 24 04:20 PM Milanova Tsveta Chief Commercial Officer Jan 20 '24 Option Exercise 0.00 5,448 0 14,852 Jan 24 04:19 PM Milanova Tsveta Chief Commercial Officer Jan 24 '24 Sale 21.64 1,618 35,014 13,234 Jan 24 04:19 PM Goff Brian Chief Executive Officer Jan 05 '24 Option Exercise 0.00 25,527 0 52,119 Jan 09 04:28 PM Goff Brian Chief Executive Officer Jan 09 '24 Sale 22.99 12,066 277,397 40,053 Jan 09 04:28 PM FOUSE JACQUALYN A Director Jan 05 '24 Option Exercise 0.00 17,500 0 124,466 Jan 09 04:26 PM FOUSE JACQUALYN A Director Jan 09 '24 Sale 22.99 8,391 192,909 116,075 Jan 09 04:26 PM Burns James William Chief Legal Officer Jan 05 '24 Option Exercise 0.00 3,250 0 27,499 Jan 09 04:25 PM Burns James William Chief Legal Officer Jan 09 '24 Sale 22.99 1,163 26,737 26,336 Jan 09 04:25 PM Gheuens Sarah Chief Medical Officer Jan 05 '24 Option Exercise 0.00 5,000 0 29,658 Jan 09 04:22 PM Gheuens Sarah Chief Medical Officer Jan 09 '24 Sale 22.99 1,789 41,129 27,869 Jan 09 04:22 PM Milanova Tsveta Chief Commercial Officer Jan 03 '24 Option Exercise 0.00 8,475 0 12,306 Jan 05 04:10 PM Milanova Tsveta Chief Commercial Officer Jan 05 '24 Sale 22.32 2,902 64,773 9,404 Jan 05 04:10 PM
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