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Last Close
Feb 13  •  04:00PM ET
3.20
Dollar change
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Feb 12, 10:56 AMGuggenheim Biotech Summit presentation on NMRA-511 efficacy drove the intraday gain.
Index- P/E- EPS (ttm)-1.46 Insider Own65.32% Shs Outstand161.95M Perf Week50.94%
Market Cap534.69M Forward P/E- EPS next Y-0.97 Insider Trans5.44% Shs Float57.94M Perf Month48.84%
Enterprise Value383.25M PEG- EPS next Q-0.33 Inst Own20.73% Short Float9.73% Perf Quarter11.89%
Income-236.30M P/S- EPS this Y6.93% Inst Trans0.57% Short Ratio3.50 Perf Half Y102.53%
Sales0.00M P/B3.92 EPS next Y32.01% ROA-89.11% Short Interest5.63M Perf YTD78.77%
Book/sh0.82 P/C3.12 EPS next 5Y12.08% ROE-104.35% 52W High3.46 -7.65% Perf Year89.35%
Cash/sh1.03 P/FCF- EPS past 3/5Y0.69% -586.93% ROIC-155.47% 52W Low0.61 423.73% Perf 3Y-
Dividend Est.- EV/EBITDA- Sales past 3/5Y- - Gross Margin- Volatility16.82% 9.51% Perf 5Y-
Dividend TTM- EV/Sales- EPS Y/Y TTM20.71% Oper. Margin- ATR (14)0.25 Perf 10Y-
Dividend Ex-Date- Quick Ratio6.85 Sales Y/Y TTM- Profit Margin- RSI (14)77.87 Recom1.89
Dividend Gr. 3/5Y- - Current Ratio6.85 EPS Q/Q22.86% SMA2041.59% Beta2.47 Target Price9.14
Payout- Debt/Eq0.15 Sales Q/Q- SMA5052.94% Rel Volume2.30 Prev Close3.25
Employees110 LT Debt/Eq0.15 EarningsNov 06 BMO SMA20087.38% Avg Volume1.61M Price3.20
IPOSep 15, 2023 Option/ShortYes / Yes EPS/Sales Surpr.-5.11% - Trades Volume3,698,883 Change-1.54%
Date Action Analyst Rating Change Price Target Change
Jan-12-26Initiated Leerink Partners Outperform $8
Dec-01-25Upgrade RBC Capital Mkts Sector Perform → Outperform $7
Oct-27-25Upgrade Guggenheim Neutral → Buy $14
Sep-16-25Downgrade JP Morgan Neutral → Underweight
Apr-02-25Downgrade BofA Securities Buy → Underperform $1
Mar-10-25Downgrade William Blair Outperform → Mkt Perform
Mar-07-25Downgrade Stifel Buy → Hold $6 → $2
Mar-07-25Downgrade Guggenheim Buy → Neutral
Jan-02-25Downgrade RBC Capital Mkts Outperform → Sector Perform $29 → $4
Nov-05-24Downgrade JP Morgan Overweight → Neutral $18 → $15
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Neumora Therapeutics, Inc. is a clinical-stage biotechnology company. It offers a precision medicine approach for brain diseases through the integration of data science and neuroscience. The firm focuses on advancing medicines for therapeutically relevant targets implicated in CNS diseases, targeting novel mechanisms of action with best-in-class pharmacology. The company was founded by Paul L. Berns, Carol Suh and Mike Poole in November 2019 and is headquartered in Watertown, MA.
Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total SEC Form 4
Aurora Daljit SinghSee RemarksNov 11 '25Sale2.68114,703307,0260Nov 13 04:39 PM
Aurora Family TrustDirectorNov 11 '25Proposed Sale2.68114,703307,027Nov 12 07:54 PM
Burow KristinaDirectorOct 27 '25Buy2.611,915,7004,999,9776,046,907Oct 29 07:22 PM
ARCH Venture Partners XII, LLC10% OwnerOct 27 '25Buy2.611,915,7004,999,9776,046,907Oct 29 07:21 PM
ARCH Venture Partners X, LLC10% OwnerOct 27 '25Buy2.611,915,7004,999,9776,046,907Oct 29 07:19 PM
Henry GosebruchOfficerMar 12 '25Proposed Sale1.4315,00021,450Mar 12 04:49 PM
BERNS PAUL LSee RemarksFeb 18 '25Sale1.6913,87123,4687,405,004Feb 20 05:14 PM
Milligan Michael LeeSee RemarksFeb 18 '25Sale1.691,9783,35122,470Feb 20 05:14 PM
Aurora Daljit SinghChief Strategy OfficerFeb 18 '25Sale1.688,56514,34788,935Feb 20 05:13 PM
Lenz Robert A.Head of R&DFeb 18 '25Sale1.675,6149,383309,092Feb 20 05:12 PM
Pinto JoshuaPresidentFeb 18 '25Sale1.678,04813,47776,952Feb 20 05:11 PM
Suh Carol Y.OfficerFeb 18 '25Proposed Sale1.689,54016,020Feb 18 05:51 PM
Milligan Michael LeeOfficerFeb 18 '25Proposed Sale1.691,9783,351Feb 18 05:49 PM
Pinto JoshuaOfficerFeb 18 '25Proposed Sale1.678,04813,478Feb 18 05:45 PM
Lenz Robert A.OfficerFeb 18 '25Proposed Sale1.675,6149,383Feb 18 05:43 PM
Gosebruch Henry OOfficerFeb 18 '25Proposed Sale1.676,85711,462Feb 18 05:41 PM
BERNS PAUL LOfficerFeb 18 '25Proposed Sale1.6913,87123,468Feb 18 05:40 PM
Aurora Daljit SinghOfficerFeb 18 '25Proposed Sale1.688,56514,348Feb 18 05:38 PM
Last Close
Feb 13  •  04:00PM ET
42.70
Dollar change
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CRNX Crinetics Pharmaceuticals Inc daily Stock Chart
IndexRUT P/E- EPS (ttm)-4.53 Insider Own7.11% Shs Outstand102.51M Perf Week-5.70%
Market Cap4.38B Forward P/E- EPS next Y-4.97 Insider Trans-1.07% Shs Float95.28M Perf Month-22.95%
Enterprise Value3.33B PEG- EPS next Q-1.35 Inst Own106.80% Short Float15.03% Perf Quarter-0.28%
Income-423.10M P/S2860.90 EPS this Y-36.38% Inst Trans4.67% Short Ratio11.45 Perf Half Y43.82%
Sales1.53M P/B3.77 EPS next Y1.22% ROA-39.66% Short Interest14.32M Perf YTD-8.27%
Book/sh11.34 P/C4.01 EPS next 5Y-0.76% ROE-44.42% 52W High57.99 -26.37% Perf Year21.10%
Cash/sh10.66 P/FCF- EPS past 3/5Y-9.67% -12.11% ROIC-37.95% 52W Low24.10 77.18% Perf 3Y112.97%
Dividend Est.- EV/EBITDA- Sales past 3/5Y-1.22% - Gross Margin-140.00% Volatility6.47% 5.17% Perf 5Y163.42%
Dividend TTM- EV/Sales2178.78 EPS Y/Y TTM-21.96% Oper. Margin-31130.16% ATR (14)2.73 Perf 10Y-
Dividend Ex-Date- Quick Ratio15.12 Sales Y/Y TTM- Profit Margin-27563.32% RSI (14)31.86 Recom1.19
Dividend Gr. 3/5Y- - Current Ratio15.12 EPS Q/Q-43.94% SMA20-14.49% Beta0.23 Target Price85.00
Payout- Debt/Eq0.05 Sales Q/Q- SMA50-13.91% Rel Volume1.12 Prev Close44.08
Employees437 LT Debt/Eq0.04 EarningsFeb 26 AMC SMA20010.44% Avg Volume1.25M Price42.70
IPOJul 18, 2018 Option/ShortYes / Yes EPS/Sales Surpr.-10.90% -66.73% Trades Volume1,397,324 Change-3.13%
Date Action Analyst Rating Change Price Target Change
Jan-12-26Upgrade Goldman Neutral → Buy $67
Jul-10-25Initiated Goldman Neutral $36
Mar-25-25Initiated Stifel Buy $60
Feb-11-25Initiated TD Cowen Buy
Feb-04-25Initiated Wolfe Research Peer Perform
Jan-22-25Upgrade Jefferies Hold → Buy $55
Mar-06-24Initiated Citigroup Buy $68
Jan-16-24Initiated Morgan Stanley Overweight $50
Dec-21-23Initiated Jefferies Hold $35
Nov-20-23Resumed JP Morgan Overweight $35
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Crinetics Pharmaceuticals, Inc. operates as a clinical stage pharmaceutical company focused on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. Its product candidate, CRN00808, is an oral nonpeptide somatostatin agonist for the treatment of acromegaly. The firm is also developing other oral nonpeptide somatostatin agonists for neuroendocrine tumors and hyperinsulinism, as well as an oral nonpeptide ACTH antagonist for the treatment of Cushing's disease. The company was founded by R. Scott Struthers, Yun-Fei Zhu and Stephen F. Betz in 2008 and is headquartered in San Diego, CA.
Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total SEC Form 4
DANA PIZZUTIOfficerFeb 02 '26Proposed Sale49.9410,000499,400Feb 02 04:32 PM
Kalofonos IsabelChief Commercial OfficerJan 05 '26Option Exercise40.592,500101,4753,334Jan 07 05:11 PM
Kalofonos IsabelChief Commercial OfficerJan 05 '26Sale55.002,500137,500834Jan 07 05:11 PM
ISABEL KALOFONOSOfficerJan 05 '26Proposed Sale46.732,500116,825Jan 05 04:43 PM
DANA PIZZUTIOfficerJan 02 '26Proposed Sale46.555,000232,750Jan 02 04:31 PM
Betz Stephen F.Chief Scientific OfficerDec 26 '25Option Exercise1.9118,00034,380117,713Dec 29 04:36 PM
Struthers Richard ScottPresident & CEODec 18 '25Option Exercise13.0944,742585,890364,759Dec 18 06:54 PM
Pizzuti DanaChief Med and Dev OfficerDec 01 '25Option Exercise16.895,00084,45071,837Dec 03 04:28 PM
Pizzuti DanaChief Med and Dev OfficerDec 01 '25Sale45.025,000225,10066,837Dec 03 04:28 PM
DANA PIZZUTIOfficerDec 01 '25Proposed Sale45.565,000227,800Dec 01 04:37 PM
Pizzuti DanaChief Med and Dev OfficerNov 03 '25Option Exercise16.895,00084,45071,270Nov 05 05:00 PM
Pizzuti DanaChief Med and Dev OfficerNov 03 '25Sale42.665,000213,31266,270Nov 05 05:00 PM
DANA PIZZUTIOfficerNov 03 '25Proposed Sale43.505,000217,500Nov 03 04:26 PM
Pizzuti DanaChief Med and Dev OfficerOct 01 '25Option Exercise16.895,00084,45071,270Oct 03 04:41 PM
Pizzuti DanaChief Med and Dev OfficerOct 01 '25Sale41.815,000209,05066,270Oct 03 04:41 PM
DANA PIZZUTIOfficerOct 01 '25Proposed Sale41.655,000208,250Oct 01 04:30 PM
Struthers Richard ScottPresident & CEOSep 26 '25Sale45.004,000180,000106,000Sep 30 04:42 PM
Fust Matthew KDirectorSep 26 '25Option Exercise1.9110,00019,10038,836Sep 30 04:41 PM
Fust Matthew KDirectorSep 26 '25Sale44.7516,000716,00022,836Sep 30 04:41 PM
MATTHEW K FUSTDirectorSep 26 '25Proposed Sale35.8916,000574,240Sep 26 04:27 PM
Struthers Richard ScottOfficerSep 26 '25Proposed Sale45.004,000180,000Sep 26 04:09 PM
Pizzuti DanaChief Med and Dev OfficerSep 02 '25Option Exercise16.895,00084,450101,270Sep 04 04:30 PM
Pizzuti DanaChief Med and Dev OfficerSep 02 '25Sale32.105,000160,50096,270Sep 04 04:30 PM
DANA PIZZUTIOfficerSep 02 '25Proposed Sale30.995,000154,950Sep 02 04:41 PM
Pizzuti DanaChief Med and Dev OfficerAug 22 '25Option Exercise16.8930,000506,70096,270Aug 26 04:30 PM
Pizzuti DanaChief Med and Dev OfficerAug 22 '25Sale30.4330,000912,90066,270Aug 26 04:30 PM
DANA PIZZUTIOfficerAug 22 '25Proposed Sale29.4030,000882,000Aug 22 04:44 PM
Pizzuti DanaChief Med and Dev OfficerAug 20 '25Sale29.186,492189,43766,270Aug 21 04:30 PM
DANA PIZZUTIOfficerAug 20 '25Proposed Sale29.436,492191,060Aug 20 04:24 PM
Betz Stephen F.Chief Scientific OfficerJun 12 '25Option Exercise3.3088,170291,078197,196Jun 16 04:48 PM
Betz Stephen F.Chief Scientific OfficerJun 12 '25Sale32.2397,4833,141,87799,713Jun 16 04:48 PM
STEPHEN BETZOfficerJun 12 '25Proposed Sale32.3397,4833,151,625Jun 12 04:19 PM
Struthers Richard ScottPresident & CEOApr 02 '25Option Exercise1.9181,270155,226410,417Apr 04 04:30 PM
Pizzuti DanaChief Med and Dev OfficerMar 19 '25Sale34.202,51586,02172,233Mar 21 06:34 PM
Knight Jeff E.Chief Operating OfficerMar 19 '25Sale34.207,162244,96487,491Mar 21 06:33 PM
Betz Stephen F.Chief Scientific OfficerMar 19 '25Sale34.205,770197,353108,588Mar 21 06:32 PM
Struthers Richard ScottPresident & CEOMar 19 '25Sale34.2017,338593,017329,147Mar 21 06:31 PM
Last Close
Feb 13  •  04:00PM ET
20.52
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RARE Ultragenyx Pharmaceutical Inc daily Stock Chart
Index- P/E- EPS (ttm)-5.84 Insider Own6.94% Shs Outstand96.48M Perf Week-16.92%
Market Cap1.98B Forward P/E- EPS next Y-0.87 Insider Trans-0.30% Shs Float89.85M Perf Month-14.75%
Enterprise Value2.11B PEG- EPS next Q-1.37 Inst Own99.78% Short Float10.12% Perf Quarter-38.80%
Income-575.44M P/S2.94 EPS this Y29.10% Inst Trans0.86% Short Ratio3.64 Perf Half Y-29.27%
Sales672.72M P/B215.68 EPS next Y78.85% ROA-37.91% Short Interest9.10M Perf YTD-10.78%
Book/sh0.10 P/C2.69 EPS next 5Y- ROE-656.54% 52W High46.27 -55.65% Perf Year-52.85%
Cash/sh7.64 P/FCF- EPS past 3/5Y16.78% -13.72% ROIC-72.42% 52W Low18.41 11.46% Perf 3Y-53.16%
Dividend Est.- EV/EBITDA- Sales past 3/5Y22.81% 19.95% Gross Margin83.85% Volatility7.56% 5.17% Perf 5Y-86.34%
Dividend TTM- EV/Sales3.14 EPS Y/Y TTM7.91% Oper. Margin-79.63% ATR (14)1.47 Perf 10Y-62.53%
Dividend Ex-Date- Quick Ratio1.74 Sales Y/Y TTM20.08% Profit Margin-85.54% RSI (14)30.16 Recom1.19
Dividend Gr. 3/5Y- - Current Ratio1.89 EPS Q/Q7.37% SMA20-13.77% Beta0.16 Target Price56.05
Payout- Debt/Eq- Sales Q/Q25.55% SMA50-25.38% Rel Volume2.88 Prev Close23.50
Employees1294 LT Debt/Eq- EarningsFeb 12 AMC SMA200-34.52% Avg Volume2.50M Price20.52
IPOJan 31, 2014 Option/ShortYes / Yes EPS/Sales Surpr.-18.07% 4.23% Trades Volume7,194,308 Change-12.68%
Date Action Analyst Rating Change Price Target Change
Oct-20-25Initiated Wells Fargo Overweight $65
Jul-28-25Resumed H.C. Wainwright Buy $80
May-28-25Initiated William Blair Outperform
Jun-06-24Upgrade Goldman Neutral → Buy $56 → $67
Apr-22-24Initiated RBC Capital Mkts Outperform $77
Dec-08-23Initiated Wells Fargo Overweight $72
Jun-14-23Resumed Credit Suisse Outperform $96
Jun-06-23Upgrade Evercore ISI In-line → Outperform $60 → $80
Apr-26-23Initiated Cantor Fitzgerald Overweight $114
Jan-18-23Resumed Canaccord Genuity Buy $90
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Ultragenyx Pharmaceutical, Inc. is a biopharmaceutical company, which engages in the identification, acquisition, development, and commercialization of novel products for the treatment of genetic diseases. Its products include Crysvita, Mepsevii, Dojolvi, and Evkeeza. The company was founded by Emil D. Kakkis in April 2010 and is headquartered in Novato, CA.
Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total SEC Form 4
Horn HowardChief Financial OfficerFeb 02 '26Sale23.563,06172,11788,935Feb 03 12:00 PM
HOWARD HORNOfficerFeb 02 '26Proposed Sale23.563,06172,117Feb 02 04:09 PM
Horn HowardChief Financial OfficerJan 02 '26Sale22.843,15071,94691,996Jan 05 04:07 PM
HOWARD HORNOfficerJan 02 '26Proposed Sale22.843,15071,946Jan 02 04:10 PM
Huizenga Theodore AlanSVP, Chief Accounting OfficerDec 29 '25Sale34.38852,92250,450Dec 30 01:49 PM
Horn HowardChief Financial OfficerDec 10 '25Sale36.383,081112,08795,146Dec 11 12:10 PM
HOWARD HORNOfficerDec 10 '25Proposed Sale36.383,081112,087Dec 10 04:05 PM
Horn HowardChief Financial OfficerOct 13 '25Sale31.517,942250,25298,227Oct 14 12:15 PM
Huizenga Theodore AlanSVP, Chief Accounting OfficerSep 18 '25Sale29.17641,86750,242Sep 19 06:23 PM
KARAH PARSCHAUEROfficerSep 12 '25Proposed Sale31.172,45076,366Sep 12 04:17 PM
Parschauer Karah HerdmanEVP and Chief Legal OfficerSep 12 '25Sale31.172,45076,36673,271Sep 12 04:11 PM
Huizenga Theodore AlanSVP, Chief Accounting OfficerSep 05 '25Sale31.39842,63750,306Sep 08 02:01 PM
Sanders Corazon (Corsee) D.DirectorJun 20 '25Sale37.392,40589,92315,344Jun 23 01:50 PM
CORAZON D. SANDERSDirectorJun 20 '25Proposed Sale37.392,40589,923Jun 20 04:02 PM
Crombez EricEVP and Chief Medical OfficerMay 05 '25Sale39.2452020,40571,530May 05 07:18 PM
Crombez EricEVP and Chief Medical OfficerApr 21 '25Sale35.112428,49771,680May 05 07:18 PM
Horn HowardChief Financial OfficerMar 06 '25Sale40.401,78572,114106,169Mar 10 12:53 PM
Kassberg Thomas RichardCBO & EVPMar 03 '25Sale42.106,028253,779265,238Mar 04 08:19 PM
Parschauer Karah HerdmanEVP and Chief Legal OfficerMar 03 '25Sale42.1012,846540,81775,287Mar 04 08:18 PM
Crombez EricEVP and Chief Medical OfficerMar 03 '25Sale42.108,945376,58471,922Mar 04 08:16 PM
Pinion John RichardSee RemarksMar 03 '25Sale42.1014,439607,882107,766Mar 04 08:12 PM
KAKKIS EMIL DPresident & CEOMar 03 '25Sale42.1073,4343,091,571641,731Mar 04 08:10 PM
KAKKIS EMIL DPresident & CEOFeb 28 '25Sale42.4825,0001,062,0002,158,985Mar 04 08:10 PM
Harris ErikEVP & Chief Commercial OfficerMar 03 '25Sale42.1015,103635,83687,855Mar 04 08:06 PM
Huizenga Theodore AlanSVP, Chief Accounting OfficerMar 03 '25Sale42.1096740,71150,265Mar 04 08:00 PM
Parschauer Karah HerdmanEVP and Chief Legal OfficerFeb 27 '25Sale42.882,990128,22454,991Mar 03 01:58 PM
KAKKIS EMIL DOfficerFeb 28 '25Proposed Sale42.4825,0001,062,100Feb 28 04:11 PM
Parschauer Karah HerdmanOfficerFeb 27 '25Proposed Sale42.882,990128,215Feb 27 05:08 PM