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Last Close
Feb 13  •  04:00PM ET
8.96
Dollar change
+0.11
Percentage change
1.24
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IndexRUT P/E- EPS (ttm)-5.21 Insider Own19.39% Shs Outstand53.83M Perf Week0.56%
Market Cap482.32M Forward P/E15.04 EPS next Y0.60 Insider Trans0.00% Shs Float43.39M Perf Month-2.61%
Enterprise Value160.56M PEG0.61 EPS next Q-0.56 Inst Own81.55% Short Float16.28% Perf Quarter-17.42%
Income-280.46M P/S40.91 EPS this Y-106.80% Inst Trans1.96% Short Ratio11.94 Perf Half Y11.17%
Sales11.79M P/B1.64 EPS next Y112.69% ROA-59.18% Short Interest7.06M Perf YTD-6.18%
Book/sh5.48 P/C1.46 EPS next 5Y24.74% ROE-67.63% 52W High16.67 -46.23% Perf Year-35.49%
Cash/sh6.15 P/FCF- EPS past 3/5Y- -3.15% ROIC-93.12% 52W Low4.32 107.41% Perf 3Y-83.40%
Dividend Est.- EV/EBITDA- Sales past 3/5Y-12.33% 178.00% Gross Margin69.05% Volatility4.49% 5.55% Perf 5Y-60.79%
Dividend TTM- EV/Sales13.62 EPS Y/Y TTM-112.24% Oper. Margin-1885.68% ATR (14)0.48 Perf 10Y-71.56%
Dividend Ex-Date- Quick Ratio6.61 Sales Y/Y TTM-91.16% Profit Margin-2379.59% RSI (14)46.38 Recom2.00
Dividend Gr. 3/5Y- - Current Ratio6.61 EPS Q/Q38.12% SMA20-2.45% Beta-0.25 Target Price20.33
Payout- Debt/Eq0.03 Sales Q/Q148.97% SMA50-5.52% Rel Volume0.49 Prev Close8.85
Employees163 LT Debt/Eq0.02 EarningsNov 06 AMC SMA2006.62% Avg Volume591.84K Price8.96
IPODec 21, 2012 Option/ShortYes / Yes EPS/Sales Surpr.1.03% -63.62% Trades Volume290,008 Change1.24%
Date Action Analyst Rating Change Price Target Change
May-28-25Downgrade BofA Securities Neutral → Underperform $4
May-27-25Downgrade Oppenheimer Outperform → Perform
May-27-25Downgrade Jefferies Buy → Hold $6
May-27-25Downgrade Cantor Fitzgerald Overweight → Neutral
Dec-20-24Initiated Chardan Capital Markets Buy $40
Jan-30-24Downgrade BofA Securities Buy → Neutral $68 → $38
Dec-12-23Initiated Deutsche Bank Buy $62
Apr-24-23Initiated SVB Securities Outperform $80
Jan-27-23Initiated Piper Sandler Overweight $94
Nov-04-22Downgrade RBC Capital Mkts Outperform → Sector Perform $52 → $55
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Prothena Corp. Plc is a clinical-stage neuroscience company, which engages in the discovery and development of novel therapies to change the course of devastating diseases. The firm's clinical pipeline includes both wholly owned and partnered programs being developed for the potential treatment of diseases including AL amyloidosis, ATTR amyloidosis, Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases. The company was founded in December 1969 and is headquartered in Dublin, Ireland.
Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total SEC Form 4
EcoR1 Capital, LLC10% OwnerMay 02 '25Sale8.363,317,93827,744,9298,266,342May 06 07:06 PM
EcoR1 Capital, LLC10% OwnerMay 06 '25Sale7.641,984,05315,164,7125,304,596May 06 07:06 PM
EcoR1 Capital, LLC10% OwnerMay 05 '25Sale8.11977,6937,930,1667,288,649May 06 07:06 PM
Last Close
Feb 13  •  04:00PM ET
20.52
Dollar change
-2.98
Percentage change
-12.68
%
RARE Ultragenyx Pharmaceutical Inc daily Stock Chart
Index- P/E- EPS (ttm)-5.84 Insider Own6.94% Shs Outstand96.48M Perf Week-16.92%
Market Cap1.98B Forward P/E- EPS next Y-0.89 Insider Trans-0.30% Shs Float89.85M Perf Month-14.75%
Enterprise Value2.11B PEG- EPS next Q-1.37 Inst Own99.73% Short Float10.12% Perf Quarter-38.80%
Income-575.44M P/S2.94 EPS this Y29.10% Inst Trans3.96% Short Ratio3.64 Perf Half Y-29.27%
Sales672.72M P/B215.68 EPS next Y78.38% ROA-37.91% Short Interest9.10M Perf YTD-10.78%
Book/sh0.10 P/C2.69 EPS next 5Y- ROE-656.54% 52W High46.27 -55.65% Perf Year-52.85%
Cash/sh7.64 P/FCF- EPS past 3/5Y16.78% -13.72% ROIC-72.42% 52W Low18.41 11.46% Perf 3Y-53.16%
Dividend Est.- EV/EBITDA- Sales past 3/5Y22.81% 19.95% Gross Margin83.85% Volatility7.56% 5.17% Perf 5Y-86.34%
Dividend TTM- EV/Sales3.14 EPS Y/Y TTM7.91% Oper. Margin-79.63% ATR (14)1.47 Perf 10Y-62.53%
Dividend Ex-Date- Quick Ratio1.74 Sales Y/Y TTM20.08% Profit Margin-85.54% RSI (14)30.16 Recom1.19
Dividend Gr. 3/5Y- - Current Ratio1.89 EPS Q/Q7.37% SMA20-13.77% Beta0.16 Target Price56.05
Payout- Debt/Eq- Sales Q/Q25.55% SMA50-25.38% Rel Volume2.88 Prev Close23.50
Employees1294 LT Debt/Eq- EarningsFeb 12 AMC SMA200-34.52% Avg Volume2.50M Price20.52
IPOJan 31, 2014 Option/ShortYes / Yes EPS/Sales Surpr.-18.07% 4.23% Trades Volume7,194,308 Change-12.68%
Date Action Analyst Rating Change Price Target Change
Oct-20-25Initiated Wells Fargo Overweight $65
Jul-28-25Resumed H.C. Wainwright Buy $80
May-28-25Initiated William Blair Outperform
Jun-06-24Upgrade Goldman Neutral → Buy $56 → $67
Apr-22-24Initiated RBC Capital Mkts Outperform $77
Dec-08-23Initiated Wells Fargo Overweight $72
Jun-14-23Resumed Credit Suisse Outperform $96
Jun-06-23Upgrade Evercore ISI In-line → Outperform $60 → $80
Apr-26-23Initiated Cantor Fitzgerald Overweight $114
Jan-18-23Resumed Canaccord Genuity Buy $90
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Ultragenyx Pharmaceutical, Inc. is a biopharmaceutical company, which engages in the identification, acquisition, development, and commercialization of novel products for the treatment of genetic diseases. Its products include Crysvita, Mepsevii, Dojolvi, and Evkeeza. The company was founded by Emil D. Kakkis in April 2010 and is headquartered in Novato, CA.
Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total SEC Form 4
Horn HowardChief Financial OfficerFeb 02 '26Sale23.563,06172,11788,935Feb 03 12:00 PM
HOWARD HORNOfficerFeb 02 '26Proposed Sale23.563,06172,117Feb 02 04:09 PM
Horn HowardChief Financial OfficerJan 02 '26Sale22.843,15071,94691,996Jan 05 04:07 PM
HOWARD HORNOfficerJan 02 '26Proposed Sale22.843,15071,946Jan 02 04:10 PM
Huizenga Theodore AlanSVP, Chief Accounting OfficerDec 29 '25Sale34.38852,92250,450Dec 30 01:49 PM
Horn HowardChief Financial OfficerDec 10 '25Sale36.383,081112,08795,146Dec 11 12:10 PM
HOWARD HORNOfficerDec 10 '25Proposed Sale36.383,081112,087Dec 10 04:05 PM
Horn HowardChief Financial OfficerOct 13 '25Sale31.517,942250,25298,227Oct 14 12:15 PM
Huizenga Theodore AlanSVP, Chief Accounting OfficerSep 18 '25Sale29.17641,86750,242Sep 19 06:23 PM
KARAH PARSCHAUEROfficerSep 12 '25Proposed Sale31.172,45076,366Sep 12 04:17 PM
Parschauer Karah HerdmanEVP and Chief Legal OfficerSep 12 '25Sale31.172,45076,36673,271Sep 12 04:11 PM
Huizenga Theodore AlanSVP, Chief Accounting OfficerSep 05 '25Sale31.39842,63750,306Sep 08 02:01 PM
Sanders Corazon (Corsee) D.DirectorJun 20 '25Sale37.392,40589,92315,344Jun 23 01:50 PM
CORAZON D. SANDERSDirectorJun 20 '25Proposed Sale37.392,40589,923Jun 20 04:02 PM
Crombez EricEVP and Chief Medical OfficerMay 05 '25Sale39.2452020,40571,530May 05 07:18 PM
Crombez EricEVP and Chief Medical OfficerApr 21 '25Sale35.112428,49771,680May 05 07:18 PM
Horn HowardChief Financial OfficerMar 06 '25Sale40.401,78572,114106,169Mar 10 12:53 PM
Kassberg Thomas RichardCBO & EVPMar 03 '25Sale42.106,028253,779265,238Mar 04 08:19 PM
Parschauer Karah HerdmanEVP and Chief Legal OfficerMar 03 '25Sale42.1012,846540,81775,287Mar 04 08:18 PM
Crombez EricEVP and Chief Medical OfficerMar 03 '25Sale42.108,945376,58471,922Mar 04 08:16 PM
Pinion John RichardSee RemarksMar 03 '25Sale42.1014,439607,882107,766Mar 04 08:12 PM
KAKKIS EMIL DPresident & CEOMar 03 '25Sale42.1073,4343,091,571641,731Mar 04 08:10 PM
KAKKIS EMIL DPresident & CEOFeb 28 '25Sale42.4825,0001,062,0002,158,985Mar 04 08:10 PM
Harris ErikEVP & Chief Commercial OfficerMar 03 '25Sale42.1015,103635,83687,855Mar 04 08:06 PM
Huizenga Theodore AlanSVP, Chief Accounting OfficerMar 03 '25Sale42.1096740,71150,265Mar 04 08:00 PM
Parschauer Karah HerdmanEVP and Chief Legal OfficerFeb 27 '25Sale42.882,990128,22454,991Mar 03 01:58 PM
KAKKIS EMIL DOfficerFeb 28 '25Proposed Sale42.4825,0001,062,100Feb 28 04:11 PM
Parschauer Karah HerdmanOfficerFeb 27 '25Proposed Sale42.882,990128,215Feb 27 05:08 PM