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ANRO

Alto Neuroscience Inc

Jul 03 • 03:43PM ET

2.35

Dollar change +0.05
Percentage change 2.17	%

Healthcare • Biotechnology • USA • NYSE

Peers: LLY BIIB AXSM ACAD VRTX NBIX REGN BMY CYTK SRPT

| Held by: VTI VXF VTWO SCHA IWM IWC SCHB IWO VTWG IWN

Scroll to Statements

Index	-	P/E	-	EPS (ttm)	-2.34	Insider Own	20.61%	Shs Outstand	27.07M	Perf Week	2.17%
Market Cap	63.62M	Forward P/E	-	EPS next Y	-2.76	Insider Trans	0.00%	Shs Float	21.49M	Perf Month	-10.65%
Enterprise Value	-70.69M	PEG	-	EPS next Q	-0.60	Inst Own	76.39%	Short Float	13.00%	Perf Quarter	14.63%
Income	-63.18M	P/S	-	EPS this Y	1.05%	Inst Trans	-9.28%	Short Ratio	9.25	Perf Half Y	-44.05%
Sales	0.00M	P/B	0.46	EPS next Y	-11.61%	ROA	-33.09%	Short Interest	2.79M	Perf YTD	-44.44%
Book/sh	5.14	P/C	0.40	EPS next 5Y	-5.25%	ROE	-38.04%	52W High	17.55 -86.61%	Perf Year	-79.39%
Cash/sh	5.94	P/FCF	-	EPS past 3/5Y	-90.85% -	ROIC	-38.37%	52W Low	1.60 46.87%	Perf 3Y	-
Dividend Est.	-	EV/EBITDA	-	Sales past 3/5Y	- -	Gross Margin	-	Volatility	7.05% 8.10%	Perf 5Y	-
Dividend TTM	-	EV/Sales	-	EPS Y/Y TTM	-	Oper. Margin	-	ATR (14)	0.19	Perf 10Y	-
Dividend Ex-Date	-	Quick Ratio	22.53	Sales Y/Y TTM	-	Profit Margin	-	RSI (14)	47.65	Recom	1.38
Dividend Gr. 3/5Y	- -	Current Ratio	22.53	EPS Q/Q	-12.36%	SMA20	-1.45%	Beta	1.65	Target Price	11.43
Payout	-	Debt/Eq	0.19	Sales Q/Q	-	SMA50	-4.17%	Rel Volume	0.27	Prev Close	2.30
Employees	76	LT Debt/Eq	0.18	Earnings	May 14 AMC	SMA200	-48.29%	Avg Volume	301.84K	Price	2.35
IPO	Feb 02, 2024	Option/Short	Yes / Yes	EPS/Sales Surpr.	7.99% -	Trades		Volume	83,674	Change	2.17%

Date	Action	Analyst	Rating Change	Price Target Change
Oct-23-24	Downgrade	Wedbush	Outperform → Neutral	$29 → $4
Oct-23-24	Downgrade	Rodman & Renshaw	Buy → Neutral
Sep-03-24	Initiated	Wedbush	Outperform	$29
Feb-27-24	Initiated	William Blair	Outperform
Feb-27-24	Initiated	TD Cowen	Outperform
Feb-27-24	Initiated	Stifel	Buy	$32
Feb-27-24	Initiated	Robert W. Baird	Outperform	$32
Feb-27-24	Initiated	Jefferies	Buy	$33

Jun-30-25 08:03AM	Alto Neuroscience Highlights Peer-Reviewed Publication of PAX-D Study in The Lancet Psychiatry Demonstrating Robust Clinical Effects of Pramipexole for Patients with Treatment-Resistant Depression (Business Wire)
Jun-26-25 07:33AM	Alto Neuroscience Identifies Biomarker and Reports Positive Pharmacodynamic Results from Exploratory Phase 2 Proof-of-Concept Trial of ALTO-203 (Business Wire) -10.51%
Jun-04-25 05:16AM	Regeneron makes obesity push; Atai, Alto ink brain drug deals (BioPharma Dive) -6.84%
Jun-03-25 02:48PM	Alto Neuroscience Adds 'Intriguing' Depression Asset Via Over $100 Million Deal (Benzinga)
06:03AM	Alto Neuroscience Announces Acquisition of Novel Dopamine Agonist Combination Product Candidate, Adding Late-Stage Readout in Treatment Resistant Depression Within Current Cash Runway (Business Wire)
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May-29-25 08:03AM	Alto Neuroscience Presents Data at the 2025 American Society of Clinical Psychopharmacology Annual Meeting Reinforcing Safety and Tolerability Profile for ALTO-300 in Major Depressive Disorder (Business Wire)
May-28-25 08:03AM	Alto Neuroscience to Participate in Upcoming Investor Conferences (Business Wire) -5.23%
May-14-25 04:10PM	Alto Neuroscience Reports First Quarter 2025 Financial Results and Recent Business Highlights (Business Wire) -7.17% +10.45%
Apr-28-25 08:03AM	Alto Neuroscience Presents New Data at the Society of Biological Psychiatry Annual Meeting Underscoring Precision Psychiatry Approach (Business Wire)
Apr-22-25 08:03AM	Alto Neuroscience to Participate in the JonesResearch Virtual CNS Day (Business Wire)
Apr-08-25 10:15AM	Alto Neuroscience initiated with a Buy at H.C. Wainwright (TipRanks) -10.18%
Mar-20-25 04:10PM	Alto Neuroscience Reports Full-Year 2024 Financial Results and Recent Business Highlights (Business Wire)
Mar-13-25 09:00AM	Christopher Nixon Cox Named Chairman of High-Trend International Group (PR Newswire) -8.14%
Mar-02-25 06:15AM	Jefferies Predicts Up to ~500% Jump for These 2 Strong Buy Stocks (TipRanks)
Feb-25-25 08:03AM	Alto Neuroscience to Participate in Upcoming Investor Conferences (Business Wire) -5.47%
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Feb-19-25 08:03AM	Alto Neuroscience Announces U.S. Patent Granted Covering ALTO-300 as a Treatment for Patients with Major Depressive Disorder Characterized by an Electroencephalogram Biomarker (Business Wire)
Feb-13-25 05:01AM	Alto Neuroscience reports positive outcomes from Phase IIb trial of MDD therapy (Clinical Trials Arena)
Feb-12-25 08:03AM	Alto Neuroscience Announces Favorable Outcome from Interim Analysis of ALTO-300 Phase 2b Major Depressive Disorder Trial (Business Wire)
Jan-08-25 12:00PM	All You Need to Know About Alto Neuroscience, Inc. (ANRO) Rating Upgrade to Buy (Zacks)
Dec-11-24 08:03AM	Alto Neuroscience Announces Data Presented at the 63rd Annual Meeting of the American College of Neuropsychopharmacology (Business Wire)
Nov-28-24 08:06AM	Allink Biotherapeutics Raises $42M Series A Financing to Accelerate Global Development of Bispecific Antibody and ADC Pipeline (PR Newswire)
Nov-12-24 04:10PM	Alto Neuroscience Reports Third Quarter 2024 Financial Results and Recent Business Highlights (Business Wire) -7.02%
Nov-04-24 08:00AM	Alto Neuroscience to Participate in Upcoming Investor Conferences (Business Wire) -6.78%
Oct-24-24 08:32AM	Wedbush downgrades Alto Neuroscience to Neutral following ALTO-100 readout (TipRanks) -5.28%
Oct-23-24 01:36PM	Neuropsychiatry-Focused Alto Neuroscience's Mid-Stage Depression Trial Disappoints, Analyst Notes Failure Raises Concerns About Platform (Benzinga) -69.99%
08:03AM	Alto hits new low as depression drug flunks key test (BioPharma Dive)
07:32AM	Altos Phase IIb study of ALTO-100 for MDD fails to meet primary endpoint (Clinical Trials Arena)
Oct-22-24 04:30PM	Alto Neuroscience Reports Topline Results from a Phase 2b Trial Evaluating ALTO-100 as a Treatment for Major Depressive Disorder (Business Wire)
Sep-05-24 09:27AM	15 Healthiest Countries in Asia (Insider Monkey) -5.07%
Sep-04-24 08:05AM	Alto Neuroscience Announces Peer-Reviewed Publication in the Journal of Clinical Psychiatry Demonstrating Baseline Cognitive Performance is Not a Moderator of Response to Standard-of-Care Antidepressants (Business Wire)
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Sep-03-24 08:05AM	Alto Neuroscience to Participate in Upcoming Investor Conferences (Business Wire)
Aug-13-24 04:05PM	Alto Neuroscience Reports Second Quarter 2024 Financial Results and Recent Business Highlights (Business Wire) +9.25% +6.01%
Jul-25-24 08:30AM	Alto Neuroscience Receives Funding Award from Wellcome Trust to Accelerate Development of ALTO-100 in Bipolar Depression Leveraging Precision Psychiatry Approach (Business Wire)
Jul-16-24 07:30AM	Alto Neuroscience Announces Enrollment Completion in Phase 2b Study of ALTO-100 in Major Depressive Disorder (Business Wire) +6.90%
Jul-12-24 01:58PM	Hedge Fund and Insider Trading News: David Tepper, Bill Ackman, Josh Friedman, Whale Rock Capital Management, 352 Capital, Alto Neuroscience Inc (ANRO), Lions Gate Entertainment Corp. (LGF), and More (Insider Monkey)
Jun-20-24 08:05AM	Alto Neuroscience Initiates Phase 2 Study of ALTO-101, a Novel PDE4 Inhibitor, in Cognitive Impairment Associated with Schizophrenia (Business Wire)
Jun-18-24 08:05AM	Amit Etkin, M.D., Ph.D., Founder and CEO of Alto Neuroscience, Named an EY Entrepreneur Of The Year 2024 Bay Area Award Winner (Business Wire)
Jun-10-24 09:00AM	Wake Up! 3 Lesser-Known Stocks Investors Are Sleeping On (InvestorPlace) +5.33%
May-29-24 08:05AM	Alto Neuroscience to Present at the Jefferies Global Healthcare Conference (Business Wire)
May-21-24 08:05AM	Alto Neuroscience Appoints Michael Hanley as Chief Operating Officer (Business Wire)
May-14-24 10:54PM	ANRO Stock Earnings: Alto Neuroscience Misses EPS for Q1 2024 (InvestorPlace)
04:03PM	Alto Neuroscience Reports First Quarter 2024 Financial Results and Recent Business Highlights (Business Wire)
May-09-24 08:05AM	Alto Neuroscience Announces Data Presentations Highlighting Late-Stage Clinical Pipeline and Robust Platform at Upcoming Scientific Conferences (Business Wire) +5.19%
Apr-23-24 08:05AM	Alto Neuroscience Announces Positive Phase 1 Results for ALTO-101, a Novel PDE4 Inhibitor in Development for Schizophrenia (Business Wire)
Apr-10-24 03:30PM	Insiders are Piling into These 10 Healthcare Stocks in 2024 (Insider Monkey)
Apr-09-24 09:37AM	Alto Neuroscience (ANRO): Strong Industry, Solid Earnings Estimate Revisions (Zacks)
Apr-03-24 08:05AM	Alto Neuroscience Announces Initiation of Phase 2 Study of ALTO-203 in Patients with Major Depressive Disorder (Business Wire)
Mar-21-24 04:05PM	Alto Neuroscience Reports Full Year 2023 Financial Results and Recent Business Highlights (Business Wire) +5.41%
Mar-11-24 08:05AM	Alto Neuroscience Appoints Maha Radhakrishnan, M.D., to Board of Directors (Business Wire) +5.74%
Mar-07-24 08:00AM	Alto Neuroscience to Participate in Upcoming Investor Conferences (Business Wire)
Feb-27-24 08:00AM	Alto Neuroscience to Present at the TD Cowen 44th Annual Healthcare Conference (Business Wire) -6.21%
Feb-06-24 04:05PM	Alto Neuroscience Announces Closing of Upsized Initial Public Offering and Full Exercise of the Underwriters Option to Purchase Additional Shares (Business Wire) -11.06%
Feb-01-24 08:57PM	Alto Neuroscience Announces Pricing of Upsized Initial Public Offering (Business Wire)

Alto Neuroscience, Inc. is a clinical-stage biopharmaceutical company, which engages in the development of psychiatric drugs. Its pipeline is composed of five clinical-stage assets which initially target depressive disorder and schizophrenia population. The company was founded by Amit Etkin, Dan Segal, and Wei Wu on March 25, 2019 and is headquartered in Mountain View, CA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Savitz Adam	CHIEF MEDICAL OFFICER	Jul 09 '24	Buy	12.60	12,069	152,085	36,920	Jul 11 04:15 PM
Savitz Adam	CHIEF MEDICAL OFFICER	Jul 10 '24	Buy	13.22	2,931	38,748	39,851	Jul 11 04:15 PM

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ANRO

Alto Neuroscience Inc

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