ISRG

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NEW: Price Reaction to Earnings Reports

View detailed tables showing price action before and after earnings announcements, ranging from intraday to one week out. Track how the market has reacted to past earnings to identify patterns and predict future behavior. Click here to open.

Dollar change +0.52
Percentage change 0.10	%

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Index	NDX, S&P 500	P/E	84.29	EPS (ttm)	6.22	Insider Own	0.61%	Shs Outstand	356.20M	Perf Week	-2.81%
Market Cap	186.98B	Forward P/E	66.72	EPS next Y	7.86	Insider Trans	-6.63%	Shs Float	353.99M	Perf Month	-3.21%
Income	2.24B	PEG	5.22	EPS next Q	1.75	Inst Own	86.13%	Short Float	0.98%	Perf Quarter	7.23%
Sales	7.87B	P/S	23.77	EPS this Y	20.27%	Inst Trans	-1.20%	Short Ratio	2.69	Perf Half Y	22.23%
Book/sh	43.75	P/B	11.99	EPS next Y	14.47%	ROA	13.82%	Short Interest	3.46M	Perf Year	61.15%
Cash/sh	11.87	P/C	44.18	EPS next 5Y	16.14%	ROE	15.95%	52W Range	320.26 - 556.23	Perf YTD	55.45%
Dividend Est.	-	P/FCF	319.07	EPS past 5Y	9.71%	ROI	14.39%	52W High	-5.72%	Beta	1.39
Dividend TTM	-	Quick Ratio	3.42	Sales past 5Y	14.41%	Gross Margin	66.98%	52W Low	63.75%	ATR (14)	11.45
Dividend Ex-Date	-	Current Ratio	4.30	EPS Y/Y TTM	46.62%	Oper. Margin	26.24%	RSI (14)	41.97	Volatility	2.75% 2.04%
Employees	13676	Debt/Eq	0.00	Sales Y/Y TTM	14.83%	Profit Margin	28.51%	Recom	1.85	Target Price	576.43
Option/Short	Yes / Yes	LT Debt/Eq	0.00	EPS Q/Q	34.25%	Payout	0.00%	Rel Volume	3.03	Prev Close	523.91
Sales Surprise	1.63%	EPS Surprise	12.05%	Sales Q/Q	16.88%	Earnings	Oct 17 AMC	Avg Volume	1.29M	Price	524.43
SMA20	-2.94%	SMA50	-0.25%	SMA200	15.38%	Trades		Volume	3,890,225	Change	0.10%

Date	Action	Analyst	Rating Change	Price Target Change
Dec-02-24	Upgrade	Morgan Stanley	Equal-Weight → Overweight	$522 → $650
Aug-02-24	Upgrade	Redburn Atlantic	Neutral → Buy	$380 → $510
Jul-10-24	Reiterated	Citigroup	Buy	$462 → $512
May-30-24	Initiated	Goldman	Buy	$500
Nov-17-23	Initiated	HSBC Securities	Buy	$318
Jul-19-23	Initiated	Robert W. Baird	Outperform	$377
Apr-19-23	Reiterated	Wells Fargo	Overweight	$289 → $310
Apr-19-23	Reiterated	Truist	Buy	$300 → $325
Apr-19-23	Reiterated	Stifel	Buy	$285 → $315
Apr-19-23	Reiterated	RBC Capital Mkts	Outperform	$305 → $309
Apr-19-23	Reiterated	Raymond James	Outperform	$270 → $323
Apr-19-23	Reiterated	Morgan Stanley	Equal-Weight	$265 → $285
Apr-19-23	Reiterated	JP Morgan	Overweight	$250 → $335
Apr-19-23	Reiterated	Evercore ISI	In-line	$240 → $270
Apr-19-23	Reiterated	Citigroup	Buy	$305 → $317
Apr-19-23	Reiterated	BTIG Research	Buy	$284 → $313
Apr-19-23	Reiterated	BofA Securities	Buy	$300 → $315
Mar-29-23	Initiated	UBS	Neutral	$278
Mar-23-23	Initiated	William Blair	Outperform
Oct-18-22	Initiated	Barclays	Overweight	$235

Show Previous Ratings

Dec-19-24 05:50PM	Intuitive Surgical, Inc. (ISRG) Declines More Than Market: Some Information for Investors (Zacks)
07:30AM	Intuitive Surgical price target raised to $640 from $570 at Truist (TipRanks)
Dec-17-24 10:55AM	Palantirs high valuation paints a stark picture of the S&P 500s priciest picks (MarketWatch)
09:00AM	Investors Heavily Search Intuitive Surgical, Inc. (ISRG): Here is What You Need to Know (Zacks)
06:07AM	Prediction: 2 Stocks That'll Be Worth More Than Palantir 5 Years From Now (Motley Fool)
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Dec-16-24 06:01AM	The Art of Valuation: Discovering Intuitive Surgical Inc's Intrinsic Value (GuruFocus.com)
Dec-13-24 05:50PM	Intuitive Surgical, Inc. (ISRG) Stock Moves -0.94%: What You Should Know (Zacks)
Dec-10-24 04:54AM	Intuitives da Vinci beats non-robotic surgeries in cancer meta-analysis (MedTech Dive)
Dec-09-24 08:42AM	Are Options Traders Betting on a Big Move in Intuitive Surgical (ISRG) Stock? (Zacks)
Dec-06-24 09:00AM	Here is What to Know Beyond Why Intuitive Surgical, Inc. (ISRG) is a Trending Stock (Zacks)
Dec-05-24 04:15PM	Meta-analysis published in Annals of Surgery shows benefits of da Vinci surgery across seven oncologic procedures compared to laparoscopic and open (GlobeNewswire)
Dec-04-24 05:50PM	Intuitive Surgical, Inc. (ISRG) Beats Stock Market Upswing: What Investors Need to Know (Zacks)
08:45AM	Artificial Intelligence (AI) Redefining Medical Diagnostics Industry That's Expected to be a $7.2 Billion Market by 2029 (GlobeNewswire)
Dec-03-24 02:05PM	Intuitive Surgical, Inc. (ISRG): A Bull Case Theory (Insider Monkey)
12:47PM	These are the sectors investors need to watch (Yahoo Finance Video)
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12:00PM	Intuitive Surgical (ISRG) Upgraded to Buy: Here's What You Should Know (Zacks)
05:00AM	How CMR Surgical is taking on robotics 800-pound gorilla (MedTech Dive)
Dec-02-24 02:29PM	Morgan Stanley Maintains Positive MedTech Outlook Despite Setbacks in 2024, Upgrades Intuitive Surgical And Stryker, Downgrades Nevro And Glaukos (Benzinga)
06:00AM	Invest with Confidence: Intrinsic Value Unveiled of Intuitive Surgical Inc (GuruFocus.com)
Nov-28-24 07:45AM	2 Excellent Healthcare Stocks to Hold Through the Next Decade (Motley Fool)
Nov-25-24 09:30AM	Wall Street Bulls Look Optimistic About Intuitive Surgical (ISRG): Should You Buy? (Zacks)
09:00AM	Is Trending Stock Intuitive Surgical, Inc. (ISRG) a Buy Now? (Zacks)
Nov-18-24 09:15PM	The Art of Valuation: Discovering Intuitive Surgical Inc's Intrinsic Value (GuruFocus.com)
09:40AM	Is Intuitive Surgical (ISRG) Outperforming Other Medical Stocks This Year? (Zacks)
Nov-16-24 10:04AM	Ignore The Valuation And Buy The Growth In Intuitive Surgical (ISRG) (Insider Monkey)
Nov-13-24 11:58AM	J&J MedTech wins IDE for Ottava to greenlight trials for surgical robot (Medical Device Network)
Nov-12-24 09:00AM	Intuitive Surgical, Inc. (ISRG) is Attracting Investor Attention: Here is What You Should Know (Zacks)
Nov-10-24 05:48AM	Intuitive Surgical (ISRG): The Hidden Gem in Robotics Stocks Dominating Healthcare (Insider Monkey)
Nov-09-24 05:14AM	3 Soaring Stocks to Hold for the Next 20 Years (Motley Fool)
Nov-08-24 09:30AM	Wall Street Analysts Think Intuitive Surgical (ISRG) Is a Good Investment: Is It? (Zacks)
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Nov-05-24 12:40PM	3 Robotic Stocks To Play AI As Nvidia Rally Slows (Insider Monkey)
Nov-04-24 06:00AM	Unlocking Intrinsic Value: Analysis of Intuitive Surgical Inc (GuruFocus.com)
Nov-01-24 09:00AM	Intuitive Surgical, Inc. (ISRG) Is a Trending Stock: Facts to Know Before Betting on It (Zacks)
Oct-30-24 12:32PM	Why IBD Stock Of The Day Intuitive Surgical Is Eyeing Yet Another Breakout (Investor's Business Daily)
09:47AM	Intuitive Surgical, Inc. (ISRG): Among UBS Top Tech Based Disruptive Stocks For 2030 (Insider Monkey)
Oct-28-24 07:00AM	Deborah Kilpatrick Joins Sonder Capital as its Newest Venture Partner (PR Newswire)
Oct-25-24 07:00AM	Got $1,000? 2 Healthcare Stocks to Buy and Hold Forever. (Motley Fool)
Oct-23-24 09:30AM	Intuitive Surgical (ISRG) Is Considered a Good Investment by Brokers: Is That True? (Zacks)
04:28AM	Has Intuitive Surgical (NASDAQ:ISRG) Stocks Valuation Gotten Out of Hand? (TipRanks)
Oct-22-24 09:53AM	Up 800% the Past Decade, Can the Momentum Continue for This Hot Stock? (Motley Fool)
Oct-21-24 05:00PM	Eaton Vance Worldwide Health Sciences Fund Sharpens Focus on Humana Inc in Q3 2024 (GuruFocus.com)
04:05PM	AI Leaders Broadcom And SentinelOne Lead 5 Stocks Near Buy Points (Investor's Business Daily)
02:24PM	AI Leaders Broadcom, SentinelOne Lead 5 Stocks Near Buy Points (Investor's Business Daily)
09:00AM	Intuitive Surgical, Inc. (ISRG) is Attracting Investor Attention: Here is What You Should Know (Zacks)
08:00AM	Navigating Market Uncertainty: Intrinsic Value of Intuitive Surgical Inc (GuruFocus.com)
Oct-19-24 07:52AM	Intuitive Surgical price target raised to $525 from $475 at Stifel (TipRanks)
01:04AM	Decoding Intuitive Surgical Inc (ISRG): A Strategic SWOT Insight (GuruFocus.com)
Oct-18-24 07:30PM	Compared to Estimates, Intuitive Surgical (ISRG) Q3 Earnings: A Look at Key Metrics (Zacks) +10.01%
04:32PM	Intuitive Surgical stock moves higher on Q3 earnings beat (Yahoo Finance Video)
04:28PM	Intuitive Surgical Breaks Out On Massive Earnings Beat, But 2025 Launch Remains Key (Investor's Business Daily)
04:22PM	Intuitive Surgical Shares Surge 6% as Q3 Earnings Beat Expectations (GuruFocus.com)
03:26PM	Intuitive Surgical (ISRG): Financial Growth Fueled by AI-Driven Da Vinci Systems (Insider Monkey)
02:54PM	Robotic Surgery Leader, Mobile Carrier Jump To New Highs (Investor's Business Daily)
12:48PM	Intuitive Surgical Surges 9% on Strong Q3 Results and Regulatory Wins (GuruFocus.com)
11:38AM	Intuitive Surgical Stock Pops on Earnings Beat. What Wall Street Thinks of the Results. (Barrons.com)
10:14AM	Intuitive Surgical Stock Hits Record High on da Vinci Device Demand (Investopedia)
09:27AM	Intuitive Surgical Eyes Breakout On Massive Earnings Beat, But 2025 Launch Remains Key (Investor's Business Daily)
07:16AM	Q3 2024 Intuitive Surgical Inc Earnings Call (Thomson Reuters StreetEvents)
05:01AM	Analyst Report: Intuitive Surgical, Inc. (Morningstar Research)
04:34AM	Intuitive Surgical shares jump 6% after Q3 earnings beat, da Vinci ramp (Investing.com)
03:04AM	Intuitive Surgical Inc (ISRG) Q3 2024 Earnings Call Highlights: Strong Revenue and Procedure ... (GuruFocus.com)
Oct-17-24 09:15PM	Intuitive Surgical (ISRG) Q3 2024 Earnings Call Transcript (Motley Fool)
05:15PM	Intuitive Surgical, Inc. (ISRG) Beats Q3 Earnings and Revenue Estimates (Zacks)
04:54PM	Intuitive Surgical Adds To 40% Run With Massive Profit Beat, Strong Procedure Growth (Investor's Business Daily)
04:05PM	Intuitive Announces Third Quarter Earnings (GlobeNewswire)
01:20PM	Intuitive Surgical's Earnings Are On Deck. Will Its 41% Surge Remain Intact? (Investor's Business Daily)
Oct-16-24 12:10PM	Will Intuitive Surgical (ISRG) Beat Estimates Again in Its Next Earnings Report? (Zacks)
Oct-15-24 12:33PM	Analysts reboot Intuitive Surgical stock price target ahead of earnings (TheStreet)
Oct-14-24 09:15AM	Intuitive Surgical (ISRG) Q3 Earnings Preview: What You Should Know Beyond the Headline Estimates (Zacks)
Oct-13-24 06:00AM	What To Expect in the Markets This Week (Investopedia)
Oct-11-24 11:39PM	RBC Capital Raises Intuitive Surgical, Inc. (ISRG) Price Target to $525, Maintains Outperform Rating Amid Positive Q3 Utilization Trends in MedTech (Insider Monkey)
06:45AM	2 Soaring Growth Stocks Up 45% and 60% in 2024 to Buy Right Now (Motley Fool)
Oct-09-24 06:00PM	Intuitive Surgical, Inc. (ISRG) Outperforms Broader Market: What You Need to Know (Zacks)
04:47PM	LLY, NVS, or ISRG: Which Healthcare Stock Scores Wall Streets Strong Buy Rating? (TipRanks)
02:33AM	Intuitive Surgical, Inc. (ISRG): Stock That Will Make You Rich in 5-10 Years (Insider Monkey)
Oct-07-24 09:00AM	Intuitive Surgical, Inc. (ISRG) Is a Trending Stock: Facts to Know Before Betting on It (Zacks)
Oct-04-24 01:22PM	Is Intuitive Surgical, Inc. (NASDAQ:ISRG) The Top Goldman Sachs Fund Manager Stock Pick? (Insider Monkey)
09:30AM	Wall Street Analysts See Intuitive Surgical (ISRG) as a Buy: Should You Invest? (Zacks)
08:00AM	Unlocking Intrinsic Value: Analysis of Intuitive Surgical Inc (GuruFocus.com)
Oct-03-24 08:30AM	Eli Lilly Leads S&P Health Care Stocks With 1,241% Gain. But The Others Aren't Slackers. (Investor's Business Daily)
Oct-01-24 06:00PM	Intuitive Surgical, Inc. (ISRG) Registers a Bigger Fall Than the Market: Important Facts to Note (Zacks)
08:00AM	These Are The Best Second-Chance Stocks Around (Investor's Business Daily)
Sep-28-24 09:56PM	Jim Cramer Prefers Intuitive Surgical, Inc. (NASDAQ:ISRG) Over Procept Biorobotics (Insider Monkey)
Sep-25-24 06:00PM	Intuitive Surgical, Inc. (ISRG) Flat As Market Sinks: What You Should Know (Zacks)
08:29AM	Intuitive Surgical, Inc. (ISRG): Hedge Funds Are Bullish On This Trending AI Stock Right Now (Insider Monkey)
Sep-24-24 09:00AM	Intuitive Surgical, Inc. (ISRG) is Attracting Investor Attention: Here is What You Should Know (Zacks)
Sep-21-24 06:20AM	Bull Market Buys: 2 Nasdaq Stocks to Own for the Long Run (Motley Fool)
Sep-20-24 10:00AM	Intuitive Surgical Has Stellar Performance, but Is Priced to Perfection (GuruFocus.com)
08:00AM	Intuitive Surgical Inc: An Exploration into Its Intrinsic Value (GuruFocus.com)
Sep-19-24 05:50PM	Here's Why Intuitive Surgical, Inc. (ISRG) Gained But Lagged the Market Today (Zacks)
Sep-18-24 09:30AM	Is It Worth Investing in Intuitive Surgical (ISRG) Based on Wall Street's Bullish Views? (Zacks)
08:16AM	Intuitive Surgical, Inc. (ISRG): A Bear Case Theory (Insider Monkey)
08:00AM	CIBC introduces additional Canadian Depositary Receipts ("CDRs") (PR Newswire)
Sep-17-24 06:00PM	Intuitive Surgical, Inc. (ISRG) Stock Falls Amid Market Uptick: What Investors Need to Know (Zacks)
Sep-12-24 10:54AM	Intuitive Surgical, Inc. (ISRG): A Very Important AI Stock According to BlackRock (Insider Monkey)
Sep-11-24 05:50PM	Intuitive Surgical, Inc. (ISRG) Rises Higher Than Market: Key Facts (Zacks)
09:00AM	Intuitive Surgical, Inc. (ISRG) Is a Trending Stock: Facts to Know Before Betting on It (Zacks)
Sep-06-24 07:51AM	Jim Cramer Says I Think If Youre Going To Be In Robotics, You Have To Be In Intuitive Surgical Inc. (ISRG) (Insider Monkey)
Sep-05-24 05:50PM	Intuitive Surgical, Inc. (ISRG) Sees a More Significant Dip Than Broader Market: Some Facts to Know (Zacks)
08:00AM	Unlocking Intrinsic Value: Analysis of Intuitive Surgical Inc (GuruFocus.com)

Intuitive Surgical, Inc. engages in the provision of robotic-assisted surgical solutions and invasive care through a comprehensive ecosystem of products and services. Its products include Da Vinci Surgical and Ion Endoluminal systems. The company was founded by Frederic H. Moll, John Gordon Freund, and Robert G. Younge in November 1995 and is headquartered in Sunnyvale, CA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Samath Jamie	CFO and Head of Business Techn	Dec 10 '24	Option Exercise	267.03	270	72,098	8,892	Dec 11 12:50 PM
Samath Jamie	CFO and Head of Business Techn	Dec 10 '24	Sale	540.15	270	145,842	8,757	Dec 11 12:50 PM
JAMIE E SAMATH	Officer	Dec 10 '24	Proposed Sale	540.15	270	145,842		Dec 10 04:02 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Nov 29 '24	Option Exercise	249.61	376	93,855	5,694	Dec 02 01:48 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Nov 29 '24	Sale	539.00	376	202,664	5,506	Dec 02 01:48 PM
Samath Jamie	CFO and Head of Business Techn	Nov 29 '24	Option Exercise	249.61	188	46,928	8,851	Dec 02 01:35 PM
Samath Jamie	CFO and Head of Business Techn	Nov 29 '24	Sale	539.00	188	101,332	8,757	Dec 02 01:35 PM
JAMIE E SAMATH	Officer	Nov 29 '24	Proposed Sale	539.00	188	101,332		Nov 29 01:27 PM
ROBERT DESANTIS	Officer	Nov 29 '24	Proposed Sale	539.00	376	202,664		Nov 29 01:25 PM
Samath Jamie	CFO and Head of Business Techn	Nov 26 '24	Option Exercise	296.51	108	32,023	8,811	Nov 26 06:03 PM
Samath Jamie	CFO and Head of Business Techn	Nov 26 '24	Sale	542.06	108	58,542	8,757	Nov 26 06:03 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Nov 26 '24	Option Exercise	296.51	396	117,417	5,704	Nov 26 05:42 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Nov 26 '24	Sale	542.06	396	214,656	5,506	Nov 26 05:42 PM
JAMIE E SAMATH	Officer	Nov 26 '24	Proposed Sale	542.06	108	58,542		Nov 26 04:08 PM
ROBERT DESANTIS	Officer	Nov 26 '24	Proposed Sale	542.06	396	214,656		Nov 26 04:06 PM
Curet Myriam	EVP & Chief Medical Officer	Nov 12 '24	Option Exercise	197.39	13,466	2,658,000	5,298	Nov 13 04:21 PM
Curet Myriam	EVP & Chief Medical Officer	Nov 12 '24	Sale	535.96	13,466	7,217,196	298	Nov 13 04:21 PM
Samath Jamie	See Remarks	Nov 08 '24	Option Exercise	245.13	22,903	5,614,260	31,660	Nov 12 07:16 PM
Samath Jamie	See Remarks	Nov 11 '24	Option Exercise	266.89	269	71,793	9,026	Nov 12 07:16 PM
Samath Jamie	See Remarks	Nov 08 '24	Sale	525.00	22,903	12,024,075	8,757	Nov 12 07:16 PM
Samath Jamie	See Remarks	Nov 11 '24	Sale	539.89	269	145,230	8,757	Nov 12 07:16 PM
MYRIAM CURET MCADAMS	Officer	Nov 12 '24	Proposed Sale	535.96	13,466	7,217,196		Nov 12 04:06 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Nov 11 '24	Option Exercise	267.19	239	63,858	5,626	Nov 12 01:34 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Nov 11 '24	Sale	539.89	239	129,034	5,506	Nov 12 01:34 PM
JAMIE E SAMATH	Officer	Nov 11 '24	Proposed Sale	539.89	269	145,230		Nov 12 11:43 AM
ROBERT DESANTIS	Officer	Nov 11 '24	Proposed Sale	539.89	239	129,034		Nov 12 11:42 AM
JAMIE E SAMATH	Officer	Nov 08 '24	Proposed Sale	525.00	22,903	12,024,075		Nov 08 04:17 PM
GUTHART GARY S	CEO	Oct 30 '24	Option Exercise	59.23	25,200	1,492,541	42,370	Oct 31 12:22 PM
GUTHART GARY S	CEO	Oct 30 '24	Sale	511.63	18,151	9,286,674	24,219	Oct 31 12:22 PM
GUTHART GARY S	CEO	Oct 30 '24	Sale	510.64	7,440	3,799,129	19,920	Oct 31 12:22 PM
GARY S GUTHART	Officer	Oct 30 '24	Proposed Sale	511.63	18,151	9,286,672		Oct 30 04:25 PM
GUTHART GARY S	Officer	Oct 30 '24	Proposed Sale	516.31	7,440	3,841,346		Oct 30 10:44 AM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Oct 25 '24	Option Exercise	272.09	1,012	275,360	5,704	Oct 29 06:55 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Oct 28 '24	Option Exercise	294.52	584	171,999	5,704	Oct 29 06:55 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Oct 29 '24	Option Exercise	208.90	188	39,273	5,694	Oct 29 06:55 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Oct 25 '24	Sale	514.00	1,012	520,168	5,506	Oct 29 06:55 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Oct 28 '24	Sale	513.66	584	299,977	5,506	Oct 29 06:55 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Oct 29 '24	Sale	506.52	188	95,226	5,506	Oct 29 06:55 PM
ROBERT DESANTIS	Officer	Oct 29 '24	Proposed Sale	506.52	188	95,226		Oct 29 04:02 PM
Brosius Mark	SVP & Chief Mfg and Supply Cha	Oct 25 '24	Sale	514.00	22	11,308	207	Oct 28 04:29 PM
Brosius Mark	SVP & Chief Mfg and Supply Cha	Oct 28 '24	Sale	513.66	22	11,301	185	Oct 28 04:29 PM
MARK BROSIUS	Officer	Oct 28 '24	Proposed Sale	513.66	22	11,301		Oct 28 04:05 PM
ROBERT DESANTIS	Officer	Oct 28 '24	Proposed Sale	513.66	584	299,977		Oct 28 04:04 PM
MARK BROSIUS	Officer	Oct 25 '24	Proposed Sale	514.00	22	11,308		Oct 25 04:11 PM
ROBERT DESANTIS	Officer	Oct 25 '24	Proposed Sale	514.00	1,012	520,168		Oct 25 04:11 PM
Brosius Mark	SVP & Chief Mfg and Supply Cha	Oct 22 '24	Option Exercise	77.00	2,106	162,160	2,401	Oct 24 05:58 PM
Brosius Mark	SVP & Chief Mfg and Supply Cha	Oct 22 '24	Sale	515.00	2,128	1,095,920	273	Oct 24 05:58 PM
Brosius Mark	SVP & Chief Mfg and Supply Cha	Oct 23 '24	Sale	513.89	22	11,306	251	Oct 24 05:58 PM
Brosius Mark	SVP & Chief Mfg and Supply Cha	Oct 24 '24	Sale	510.79	22	11,237	229	Oct 24 05:58 PM
MARK BROSIUS	Officer	Oct 24 '24	Proposed Sale	510.79	22	11,237		Oct 24 04:08 PM
MARK BROSIUS	Officer	Oct 23 '24	Proposed Sale	513.89	22	11,306		Oct 23 04:02 PM
Miller Brian Edward	EVP & Chief Digital Officer	Oct 22 '24	Sale	515.00	2,553	1,314,795	7,066	Oct 23 07:38 AM
BRIAN MILLER	Officer	Oct 22 '24	Proposed Sale	515.00	2,553	1,314,795		Oct 22 04:02 PM
MARK BROSIUS	Officer	Oct 22 '24	Proposed Sale	515.00	2,128	1,095,920		Oct 22 04:01 PM
MOHR MARSHALL	Officer	Oct 22 '24	Proposed Sale	515.00	29,787	15,340,305		Oct 22 01:01 PM
LOEB GARY	General Counsel	Oct 10 '24	Option Exercise	0.00	2,613	0	4,208	Oct 10 02:36 PM
Ladd Amy L	Director	Sep 13 '24	Sale	490.28	450	220,626	821	Sep 16 12:30 PM
Brosius Mark	See Remarks	Sep 12 '24	Option Exercise	59.46	2,115	125,763	2,410	Sep 16 12:29 PM
Brosius Mark	See Remarks	Sep 12 '24	Sale	491.91	2,115	1,040,390	295	Sep 16 12:29 PM
AMY L LADD	Director	Sep 13 '24	Proposed Sale	490.28	450	220,626		Sep 13 04:08 PM
MARK BROSIUS	Officer	Sep 12 '24	Proposed Sale	491.91	2,115	1,040,390		Sep 12 04:52 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Sep 10 '24	Option Exercise	267.03	238	63,553	5,625	Sep 10 07:07 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Sep 10 '24	Sale	477.50	238	113,645	5,506	Sep 10 07:07 PM
ROBERT DESANTIS	Officer	Sep 10 '24	Proposed Sale	477.50	238	113,645		Sep 10 04:01 PM
LOEB GARY	General Counsel	Sep 09 '24	Sale	475.00	300	142,500	1,595	Sep 09 06:38 PM
GARY LOEB	Officer	Sep 09 '24	Proposed Sale	475.00	300	142,500		Sep 09 04:02 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Aug 28 '24	Option Exercise	290.33	188	54,582	5,694	Aug 29 05:49 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Aug 29 '24	Option Exercise	208.90	188	39,273	5,694	Aug 29 05:49 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Aug 28 '24	Sale	482.93	188	90,791	5,506	Aug 29 05:49 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Aug 29 '24	Sale	482.21	188	90,655	5,506	Aug 29 05:49 PM
ROBERT DESANTIS	Officer	Aug 29 '24	Proposed Sale	482.21	188	90,655		Aug 29 04:16 PM
ROBERT DESANTIS	Officer	Aug 28 '24	Proposed Sale	482.93	188	90,791		Aug 28 04:22 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Aug 26 '24	Option Exercise	296.51	396	117,417	5,704	Aug 26 06:49 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Aug 26 '24	Sale	486.88	396	192,804	5,506	Aug 26 06:49 PM
Charlton Henry L	SVP & Chief Commercial and Mkt	Aug 23 '24	Option Exercise	142.20	19,758	2,809,518	28,689	Aug 26 05:04 PM
Charlton Henry L	SVP & Chief Commercial and Mkt	Aug 23 '24	Sale	486.84	40,243	19,591,843	3,001	Aug 26 05:04 PM
ROBERT DESANTIS	Officer	Aug 26 '24	Proposed Sale	486.88	396	192,804		Aug 26 04:03 PM
HENRY CHARLTON	Officer	Aug 23 '24	Proposed Sale	486.84	40,243	19,591,840		Aug 23 04:13 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Aug 12 '24	Option Exercise	267.03	240	64,087	5,626	Aug 13 02:13 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Aug 12 '24	Sale	464.76	240	111,542	5,506	Aug 13 02:13 PM
ROBERT DESANTIS	Officer	Aug 12 '24	Proposed Sale	464.76	240	111,542		Aug 12 04:10 PM
Johnson Amal M	Director	Aug 01 '24	Option Exercise	71.32	2,943	209,904	15,218	Aug 05 01:10 PM
Johnson Amal M	Director	Aug 01 '24	Sale	443.30	2,943	1,304,632	12,275	Aug 05 01:10 PM
AMAL M JOHNSON	Director	Aug 01 '24	Proposed Sale	443.30	2,943	1,304,632		Aug 01 04:15 PM
GUTHART GARY S	CEO	Jul 30 '24	Option Exercise	57.11	25,200	1,439,200	40,558	Jul 31 01:24 PM
GUTHART GARY S	CEO	Jul 30 '24	Sale	443.07	23,388	10,362,516	17,170	Jul 31 01:24 PM
GUTHART GARY S	CEO	Jul 30 '24	Sale	445.09	7,440	3,311,480	23,640	Jul 31 01:24 PM
GARY S GUTHART	Officer	Jul 30 '24	Proposed Sale	443.07	23,388	10,362,514		Jul 30 04:38 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Jul 26 '24	Option Exercise	279.09	1,413	394,347	5,905	Jul 30 02:02 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Jul 29 '24	Option Exercise	249.61	376	93,855	5,694	Jul 30 02:02 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Jul 26 '24	Sale	438.60	1,413	619,742	5,506	Jul 30 02:02 PM
DeSantis Robert	EVP & Chief Strategy & Corp Op	Jul 29 '24	Sale	446.60	376	167,922	5,506	Jul 30 02:02 PM
GUTHART GARY S	Officer	Jul 30 '24	Proposed Sale	442.05	7,440	3,288,852		Jul 30 10:55 AM
ROBERT DESANTIS	Officer	Jul 29 '24	Proposed Sale	446.60	376	167,922		Jul 29 04:36 PM
ROBERT DESANTIS	Officer	Jul 26 '24	Proposed Sale	438.60	1,413	619,742		Jul 26 04:35 PM
BARRATT CRAIG H	Director	Jul 23 '24	Option Exercise	56.97	1,400	79,764	1,400	Jul 24 02:06 PM
BARRATT CRAIG H	Director	Jul 23 '24	Sale	458.13	1,400	641,382	0	Jul 24 02:06 PM
Curet Myriam	EVP & Chief Medical Officer	Jul 23 '24	Option Exercise	177.99	2,818	501,567	3,116	Jul 24 01:47 PM
Curet Myriam	EVP & Chief Medical Officer	Jul 23 '24	Sale	458.13	2,818	1,291,010	298	Jul 24 01:47 PM
BARRATT CRAIG H	Director	Jun 12 '24	Option Exercise	56.97	1,400	79,764	1,400	Jun 12 09:18 PM

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