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UPB

Upstream Bio Inc

Mar 21 • 04:00PM ET

7.62

Dollar change -0.43
Percentage change -5.34	%

Healthcare • Biotechnology • USA • NASD

Held by: VTI IWM VXF IWO VTWO SCHA IWN FESM SBIO RSSL

Scroll to Statements

Index	RUT	P/E	-	EPS (ttm)	-	Insider Own	64.29%	Shs Outstand	53.60M	Perf Week	-20.71%
Market Cap	408.74M	Forward P/E	-	EPS next Y	-2.78	Insider Trans	8.92%	Shs Float	19.15M	Perf Month	-7.41%
Income	-	PEG	-	EPS next Q	-0.48	Inst Own	40.25%	Short Float	19.33%	Perf Quarter	-61.18%
Sales	-	P/S	-	EPS this Y	57.00%	Inst Trans	44.54%	Short Ratio	15.51	Perf Half Y	-
Book/sh	8.77	P/B	0.87	EPS next Y	-15.70%	ROA	-	Short Interest	3.70M	Perf Year	-
Cash/sh	8.77	P/C	0.87	EPS next 5Y	23.56%	ROE	-	52W Range	6.65 - 29.46	Perf YTD	-53.65%
Dividend Est.	-	P/FCF	-	EPS past 5Y	-	ROI	-	52W High	-74.13%	Beta	-
Dividend TTM	-	Quick Ratio	44.63	Sales past 5Y	47.97%	Gross Margin	-	52W Low	14.59%	ATR (14)	0.89
Dividend Ex-Date	-	Current Ratio	44.63	EPS Y/Y TTM	-	Oper. Margin	-	RSI (14)	39.14	Volatility	9.30% 10.55%
Employees	52	Debt/Eq	0.00	Sales Y/Y TTM	-	Profit Margin	-	Recom	1.00	Target Price	56.50
Option/Short	No / Yes	LT Debt/Eq	0.00	EPS Q/Q	-	Payout	-	Rel Volume	3.11	Prev Close	8.05
Sales Surprise	59.30%	EPS Surprise	22.72%	Sales Q/Q	-	Earnings	Mar 12 BMO	Avg Volume	238.67K	Price	7.62
SMA20	-9.80%	SMA50	-17.75%	SMA200	-52.95%	Trades		Volume	742,304	Change	-5.34%

Date	Action	Analyst	Rating Change	Price Target Change
Nov-05-24	Initiated	William Blair	Outperform
Nov-05-24	Initiated	TD Cowen	Buy
Nov-05-24	Initiated	Piper Sandler	Overweight	$75
Nov-05-24	Initiated	JP Morgan	Overweight	$38

Mar-12-25 07:00AM	Upstream Bio Reports Fourth Quarter and Full Year 2024 Financial Results and Recent Business Highlights (GlobeNewswire) +7.83%
Feb-25-25 08:00AM	Upstream Bio to Present at Upcoming March Investor Conferences (GlobeNewswire) -5.96%
Feb-11-25 09:00AM	Automotive Security Leaders Must Take Immediate Action to Mitigate the Surging Cyber Threats--Upstream Report Reveals Critical Gaps (PR Newswire)
Jan-06-25 08:00AM	Upstream Bio to Present at the 43rd Annual J.P. Morgan Healthcare Conference (GlobeNewswire) -7.47%
Dec-17-24 08:00AM	Upstream Bio Appoints Allison Ambrose as General Counsel (GlobeNewswire)
08:00AM	Loading…
Dec-16-24 08:00AM	Upstream Bio Announces Addition to Russell 2000 Index (GlobeNewswire) -6.12%
Nov-21-24 08:00AM	Upstream Bio to Participate in the Piper Sandler 36th Annual Healthcare Conference (GlobeNewswire)
Nov-08-24 07:11AM	Upstream Bio reports Q3 revenue $607,000 vs $621,000 last year (TipRanks)
Nov-07-24 07:00AM	Upstream Bio Reports Third Quarter 2024 Financial Results and Recent Business Highlights (GlobeNewswire)
Oct-17-24 07:02PM	Orbimed Advisors LLC Acquires New Stake in Upstream Bio Inc (GuruFocus.com) +9.66%
Oct-15-24 04:15PM	Upstream Bio Announces Closing of $293 Million Upsized Initial Public Offering, Including Full Exercise of Underwriters' Option to Purchase Additional Shares (GlobeNewswire)
Oct-14-24 06:45AM	Opening Day: Another trio of biotech IPOs make Friday debut (TipRanks) +6.27%
Oct-10-24 07:35PM	Upstream Bio Announces Pricing of Upsized Initial Public Offering (GlobeNewswire)

Upstream Bio, Inc. is a clinical-stage biotechnology company, which engages in the development of treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. It develops verekitug, the only known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin. The company was founded in April 2021 and is headquartered in Waltham, MA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Chimovits Erez	Director	Oct 15 '24	Buy	17.00	825,000	14,025,000	4,554,873	Oct 17 04:19 PM
ORBIMED ADVISORS LLC	Director	Oct 15 '24	Buy	17.00	825,000	14,025,000	4,554,873	Oct 17 04:17 PM
AI Upstream LLC	10% Owner	Oct 15 '24	Buy	17.00	1,175,000	19,975,000	1,175,000	Oct 17 04:05 PM

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UPB

Upstream Bio Inc

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