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VIR | Vir Biotechnology Inc

Index	RUT	P/E	-	EPS (ttm)	-1.97	Insider Own	34.97%	Shs Outstand	133.24M	Perf Week	-3.90%
Market Cap	1.24B	Forward P/E	-	EPS next Y	-4.30	Insider Trans	-3.43%	Shs Float	87.31M	Perf Month	-27.98%
Income	-261.97M	PEG	-	EPS next Q	-1.22	Inst Own	55.35%	Short Float / Ratio	5.24% / 2.95	Perf Quarter	-61.07%
Sales	490.72M	P/S	2.53	EPS this Y	-	Inst Trans	-5.48%	Short Interest	4.57M	Perf Half Y	-58.85%
Book/sh	13.49	P/B	0.69	EPS next Y	10.11%	ROA	-10.77%	Target Price	48.12	Perf Year	-50.33%
Cash/sh	13.86	P/C	0.67	EPS next 5Y	35.58%	ROE	-13.93%	52W Range	8.90 - 31.55	Perf YTD	-63.44%
Dividend	-	P/FCF	-	EPS past 5Y	-	ROI	-13.59%	52W High	-70.67%	Beta	0.26
Dividend %	-	Quick Ratio	8.63	Sales past 5Y	499.11%	Gross Margin	90.10%	52W Low	3.98%	ATR	0.48
Employees	576	Current Ratio	8.63	Sales Q/Q	-	Oper. Margin	-59.40%	RSI (14)	20.23	Volatility	4.29% 3.81%
Optionable	Yes	Debt/Eq	0.07	EPS Q/Q	-151.58%	Profit Margin	-53.38%	Rel Volume	0.87	Prev Close	9.35
Shortable	Yes	LT Debt/Eq	0.07	Earnings	Aug 03 AMC	Payout	0.00%	Avg Volume	1.55M	Price	9.25
Recom	1.33	SMA20	-16.78%	SMA50	-30.27%	SMA200	-58.46%	Volume	677,351	Change	-1.02%

Date	Action	Analyst	Rating Change	Price Target Change
Sep-08-23	Downgrade	BofA Securities	Buy → Neutral	$23 → $14
Mar-06-23	Upgrade	JP Morgan	Neutral → Overweight	$35 → $34
Feb-21-23	Upgrade	Goldman	Neutral → Buy	$41 → $53
Jan-27-23	Upgrade	Morgan Stanley	Underweight → Equal-Weight	$18 → $30
Sep-14-22	Initiated	SVB Leerink	Outperform	$40
Sep-09-22	Initiated	Morgan Stanley	Underweight	$15
Mar-03-22	Upgrade	Robert W. Baird	Underperform → Neutral	$36 → $28
Dec-21-21	Downgrade	Robert W. Baird	Neutral → Underperform	$36
Oct-25-21	Upgrade	JP Morgan	Underweight → Neutral	$29 → $37
Sep-22-21	Downgrade	Goldman	Buy → Neutral	$64 → $62
Jun-04-21	Resumed	Robert W. Baird	Neutral	$45
Jan-27-21	Downgrade	JP Morgan	Neutral → Underweight	$30
Jan-20-21	Reiterated	H.C. Wainwright	Buy	$100 → $125
Oct-05-20	Initiated	BofA Securities	Buy	$55
Sep-14-20	Upgrade	Goldman	Neutral → Buy	$48 → $54
Sep-11-20	Upgrade	JP Morgan	Underweight → Neutral	$29
Aug-20-20	Initiated	Needham	Buy	$62
Mar-19-20	Downgrade	JP Morgan	Neutral → Underweight	$26
Mar-13-20	Downgrade	Goldman	Buy → Neutral
Feb-27-20	Downgrade	Robert W. Baird	Neutral → Underperform	$17

Show Previous Ratings

Sep-20-23 08:00AM	Vir Biotechnology Announces First Participant Dosed in New Phase 1 Trial Evaluating VIR-1388, an Investigational T Cell Vaccine for the Prevention of HIV (GlobeNewswire)
Sep-19-23 05:07AM	Down More Than 50%: 2 Strong Buy Stocks That Are Too Cheap to Ignore (TipRanks)
Sep-08-23 09:34AM	Adobe upgraded, DigitalOcean double downgraded: Wall Street's top analyst calls (The Fly)
Aug-29-23 04:30PM	Vir Biotechnology to Participate in Upcoming Investor Healthcare Conferences (GlobeNewswire)
Aug-12-23 11:05AM	10 Oversold Healthcare Stocks to Buy (Insider Monkey)
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Aug-11-23 10:15AM	Is Vir Biotechnology Stock a Buy? (Motley Fool)
Aug-07-23 06:03AM	Analysts Just Made A Major Revision To Their Vir Biotechnology, Inc. (NASDAQ:VIR) Revenue Forecasts (Simply Wall St.)
Aug-04-23 01:40PM	Vir Biotechnology, Inc. (NASDAQ:VIR) Q2 2023 Earnings Call Transcript (Insider Monkey)
Aug-03-23 06:05PM	Vir Biotechnology, Inc. (VIR) Reports Q2 Loss, Misses Revenue Estimates (Zacks)
04:05PM	Vir Biotechnology Provides Corporate Update and Reports Second Quarter 2023 Financial Results (GlobeNewswire)
Jul-26-23 04:05PM	Vir Biotechnology to Provide Business Update and Report Second Quarter 2023 Financial Results on August 3, 2023 (GlobeNewswire)
Jul-21-23 10:11AM	Biotech Stock Roundup: BBIO, ARGX Soar on Study Results, APLS Down on Safety Issues (Zacks) +12.99%
Jul-20-23 04:50PM	Vir's flu-prevention drug fails mid-stage clinical trial, stock dips (American City Business Journals) -44.90%
11:31AM	Why Shares of Vir Biotechnology Are Plunging Thursday (Motley Fool)
08:00AM	Vir Biotechnology Announces Topline Data from Phase 2 PENINSULA Trial Evaluating VIR-2482 for the Prevention of Seasonal Influenza A Illness (GlobeNewswire)
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Jun-29-23 09:00AM	Vir Biotechnology Appoints Sasha Damouni Ellis as Executive Vice President and Chief Corporate Affairs Officer (GlobeNewswire)
Jun-25-23 08:00AM	Brii Bio Announces New Data from Partners Underscoring Potential for HBV Functional Cure at EASL Congress 2023 (PR Newswire)
Jun-24-23 05:30AM	Vir Biotechnology Presents New Data Evaluating the Potential for VIR-2218 and VIR-3434 as Therapies for Chronic Hepatitis B and Hepatitis D (GlobeNewswire)
Jun-21-23 08:00PM	VIR: Lowering target price to $26.00 (Argus Research)
Jun-07-23 02:13AM	Vir Biotechnology Announces Multiple Abstracts Highlighting New Hepatitis B and D Data Accepted for Presentation at EASL Congress 2023 (GlobeNewswire)
Jun-05-23 04:05PM	Vir Biotechnology to Participate in the 44th Annual Goldman Sachs Global Healthcare Conference (GlobeNewswire)
May-17-23 04:05PM	Vir Biotechnology to Host a Virtual-Only 2023 Annual Meeting of Stockholders (GlobeNewswire)
May-16-23 09:25AM	Billionaire Steve Cohen Snaps Up These 2 Strong Buy Stocks Heres Why You Might Want to Ride His Coattails (TipRanks)
May-15-23 08:35AM	Vir Biotechnology, Inc. (NASDAQ:VIR) is favoured by institutional owners who hold 50% of the company (Simply Wall St.)
08:00AM	Vir Biotechnology Appoints Jeff Calcagno, M.D., as Executive Vice President and Chief Business Officer (GlobeNewswire)
May-11-23 08:30AM	Vir Biotechnology Announces First Patient Dosed in New Phase 2 Chronic Hepatitis B Virus Trial Evaluating Combinations of VIR-2218, VIR-3434, PEG-IFN and an NRTI (GlobeNewswire)
May-10-23 02:07PM	7 Top-Rated Stocks That Will Boost Your Portfolio in 2023 (InvestorPlace)
May-04-23 07:45PM	Vir Biotechnology, Inc. (VIR) Reports Q1 Loss, Tops Revenue Estimates (Zacks)
05:48PM	The 7 Best Bargain Stocks to Buy for May 2023 (InvestorPlace)
04:05PM	Vir Biotechnology Provides Corporate Update and Reports First Quarter 2023 Financial Results (GlobeNewswire)
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May-03-23 04:05PM	Vir Biotechnology to Participate in the BofA Securities 2023 Health Care Conference (GlobeNewswire)
May-02-23 09:00AM	Vir Biotechnology Receives Expanded Support to Develop Its Novel T Cell Vaccine Platform with New $10 Million Grant for HIV Prevention (GlobeNewswire)
Apr-28-23 10:00AM	Twist Bioscience (TWST) Expected to Beat Earnings Estimates: Should You Buy? (Zacks)
Apr-27-23 10:03AM	Earnings Preview: Vir Biotechnology, Inc. (VIR) Q1 Earnings Expected to Decline (Zacks)
Apr-26-23 08:00PM	VIR: What does Argus have to say about VIR? (Argus Research)
Apr-11-23 04:05PM	Vir Biotechnology to Participate in the 22nd Annual Needham Virtual Healthcare Conference (GlobeNewswire)
Apr-05-23 01:40PM	7 Thrilling Biotech Stocks for Aggressive Investors to Buy (InvestorPlace)
Mar-29-23 08:40AM	Is the Options Market Predicting a Spike in Vir Biotechnology (VIR) Stock? (Zacks)
Mar-21-23 02:33PM	Strong week for Vir Biotechnology (NASDAQ:VIR) shareholders doesn't alleviate pain of three-year loss (Simply Wall St.)
Mar-08-23 04:05PM	Vir Biotechnology to Participate in the Barclays Global Healthcare Conference (GlobeNewswire)
Mar-05-23 07:30AM	As Covid Threat Weakens, This Biotech Is Still Worth a Shot (TheStreet.com)
Mar-03-23 06:57PM	The Top 7 Growth Stocks in Biotech (InvestorPlace)
Feb-28-23 04:05PM	Vir Biotechnology to Participate in the Cowen 43rd Annual Health Care Conference (GlobeNewswire)
Feb-26-23 07:13AM	Positive Sentiment Still Eludes Vir Biotechnology, Inc. (NASDAQ:VIR) Following 25% Share Price Slump (Simply Wall St.)
Feb-23-23 05:35PM	Vir Biotechnology, Inc. (VIR) Reports Q4 Loss, Misses Revenue Estimates (Zacks)
04:05PM	Vir Biotechnology Provides Corporate Update and Reports Fourth Quarter and Full Year 2022 Financial Results (GlobeNewswire)
Feb-22-23 08:30AM	Vir Biotechnology Announces Positive Final Draft Guidance on Sotrovimab from the UKs National Institute for Health and Care Excellence (NICE) (GlobeNewswire)
Feb-20-23 10:00AM	BioMarin Pharmaceutical (BMRN) Reports Next Week: Wall Street Expects Earnings Growth (Zacks)
Feb-16-23 04:05PM	Vir Biotechnology to Provide Corporate Update and Report Fourth Quarter and Full Year 2022 Financial Results on February 23, 2023 (GlobeNewswire)
10:01AM	Vir Biotechnology, Inc. (VIR) Expected to Beat Earnings Estimates: Should You Buy? (Zacks)
08:30AM	Vir Biotechnology Appoints Sung Lee as Chief Financial Officer (GlobeNewswire)
Feb-14-23 04:33PM	11 Most Undervalued Biotech Stocks To Buy According To Hedge Funds (Insider Monkey)
08:19AM	Vir Biotech To Work On Next-Gen COVID-19 Solutions Independently, Or With Other Partners, As GSK Walks Out (Benzinga)
Feb-13-23 04:45PM	Vir Biotechnology Announces Amended Collaboration Agreement with GSK (GlobeNewswire)
Feb-02-23 02:19PM	The 7 Most Undervalued Biotech Stocks to Buy in February 2023 (InvestorPlace)
Jan-31-23 10:06AM	7 Healthcare Stocks That Will Be Big Winners in 2023 (InvestorPlace)
Jan-25-23 06:05PM	'You have to have the goods': Retiring Vir CEO George Scangos looks back on building great companies (American City Business Journals)
08:29AM	Vir Biotechnology Announces Retirement of CEO George Scangos, Ph.D.; Appoints Marianne De Backer, MSc, Ph.D., MBA, as Successor (GlobeNewswire)
Jan-24-23 12:00PM	Vir Biotechnology, Inc. (VIR) Moves to Strong Buy: Rationale Behind the Upgrade (Zacks)
Jan-22-23 07:15AM	2 Stocks That Could Turn $100 Into $1,000 by 2028 (Motley Fool)
Jan-21-23 04:51PM	10 Best Healthcare Stocks For the Long Term (Insider Monkey)
07:36AM	Are Robust Financials Driving The Recent Rally In Vir Biotechnology, Inc.'s (NASDAQ:VIR) Stock? (Simply Wall St.)
Jan-20-23 09:40AM	Is Vir Biotechnology (VIR) Outperforming Other Medical Stocks This Year? (Zacks)
Jan-03-23 04:05PM	Vir Biotechnology to Highlight Anticipated 2023 Catalysts and Long-Term Growth Strategy at 41st Annual J.P. Morgan Healthcare Conference (GlobeNewswire)
Dec-31-22 08:44AM	Are Investors Undervaluing Vir Biotechnology, Inc. (NASDAQ:VIR) By 32%? (Simply Wall St.)
Dec-22-22 05:30PM	Vir Biotechnology: A 'Magic Formula' Top Performer (GuruFocus.com)
Dec-21-22 08:00AM	Vir Biotechnology Achieves Target Enrollment for Groundbreaking Phase 2 PENINSULA Trial Evaluating VIR-2482 for Prevention of Seasonal Influenza A (GlobeNewswire)
Dec-06-22 06:04AM	With 49% stake, Vir Biotechnology, Inc. (NASDAQ:VIR) seems to have captured institutional investors' interest (Simply Wall St.)
Dec-02-22 07:10AM	2 Fast-Growing Healthcare Stocks to Buy and Hold (Motley Fool)
Nov-24-22 09:55AM	Wall Street Analysts Believe Vir Biotechnology, Inc. (VIR) Could Rally 71%: Here's is How to Trade (Zacks)
Nov-22-22 09:40AM	Should Value Investors Buy Vir Biotechnology (VIR) Stock? (Zacks)
Nov-17-22 04:48PM	99 Bay Area companies named in Deloitte's Technology Fast 500 list, including its No. 1 (American City Business Journals)
04:48PM	99 Bay Area companies named in Deloitte 'fast 500' list, including its No. 1 (American City Business Journals)
09:15AM	Genmab AS Sponsored ADR (GMAB) Hits Fresh High: Is There Still Room to Run? (Zacks)
Nov-16-22 08:30AM	Vir Biotechnology Ranked the Fastest-Growing Company in North America on the 2022 Deloitte Technology Fast 500 (GlobeNewswire)
Nov-09-22 05:32AM	Vir Biotechnology Third Quarter 2022 Earnings: Beats Expectations (Simply Wall St.)
Nov-08-22 09:55AM	Wall Street Analysts Predict a 107% Upside in Vir Biotechnology, Inc. (VIR): Here's What You Should Know (Zacks)
09:40AM	Are Investors Undervaluing Dynavax Technologies (DVAX) Right Now? (Zacks)
Nov-07-22 08:57AM	Data From Multiple Ongoing Trials Of Vir Biotech's HBV Therapies Show Promising Action (Benzinga) +6.16%
Nov-06-22 10:35AM	Vir Biotechnology Presents New Data Evaluating the Potential for VIR-2218 and VIR-3434 to Achieve a Functional Cure for Chronic Hepatitis B Virus (HBV) Infection (GlobeNewswire)
Nov-05-22 08:18AM	Analyst Forecasts For Vir Biotechnology, Inc. (NASDAQ:VIR) Are Surging Higher (Simply Wall St.)
Nov-04-22 05:46PM	Top Biotech Stocks for Q4 2022 (Investopedia) +17.71%
04:16PM	Why Vir Biotechnology Jumped Nearly 19% Today (Motley Fool)
Nov-03-22 06:05PM	Vir Biotechnology, Inc. (VIR) Q3 Earnings and Revenues Surpass Estimates (Zacks)
04:03PM	Vir Biotechnology Provides Corporate Update and Reports Third Quarter 2022 Financial Results (GlobeNewswire)
Oct-31-22 07:20PM	7 Undervalued Biotech Stocks to Buy Before They Boom (InvestorPlace)
04:05PM	Vir Biotechnology Announces Multiple Abstracts Highlighting New Hepatitis B Data Accepted for Presentation at AASLDs The Liver Meeting® 2022 (GlobeNewswire)
Oct-28-22 06:06PM	Vir Biotechnology to Provide Corporate Update and Report Third Quarter 2022 Financial Results on November 3, 2022 (GlobeNewswire)
Oct-18-22 08:32AM	Vir begins dosing participants in Phase 2 clinical trial for new type of flu shot (MarketWatch)
08:00AM	Vir Biotechnology Announces First Patient Dosed in Groundbreaking Phase 2 Trial of VIR-2482 for Antibody Prophylaxis of Influenza A (GlobeNewswire)
Oct-12-22 01:27PM	Vir Biotechnology (NASDAQ:VIR shareholders incur further losses as stock declines 4.7% this week, taking one-year losses to 50% (Simply Wall St.)
Oct-11-22 04:03PM	Vir Biotechnology to Participate in the H. C. Wainwright 3rd Annual Hepatitis B Virus (HBV) Conference (GlobeNewswire)
Oct-07-22 12:33PM	Vir Biotechnology (VIR) Gains 11% This Week on BARDA Contract (Zacks)
Oct-05-22 09:37AM	How $1 billion deal with San Francisco biotech could change how we prep for flu season (American City Business Journals)
Oct-04-22 12:56PM	Vir Biotech Secures US Government Contract For Influenza & Other Infectious Disease Candidates (Benzinga) +7.67%
09:01AM	Vir's stock gains 10% after announcing new flu contract with the U.S. (MarketWatch)
08:00AM	Vir Biotech gets U.S. funding for flu-prevention antibody (Reuters)
08:00AM	Vir Biotechnology Awarded U.S. Government Contract to Support Pandemic Preparedness for Influenza and Other Infectious Disease Threats (GlobeNewswire)
Sep-22-22 08:00AM	Vir Biotechnology Announces First Patient Dosed in the Phase 2 SOLSTICE Trial Evaluating VIR-2218 and VIR-3434 for the Treatment of Chronic Hepatitis D Virus Infection (GlobeNewswire)
Sep-20-22 09:16PM	3 Biotech Stocks to Buy Now for Extraordinary Gains (InvestorPlace)

Vir Biotechnology, Inc. operates as a clinical-stage immunology company that focuses on combining immunologic insights with cutting-edge technologies to treat and prevent serious infectious diseases. The firm's technology platforms include antibody, T cell, innate immunity and siRNA, which are designed to stimulate and enhance the immune system by exploiting critical observations of natural immune processes. The company was founded by Robert Taylor Nelsen, Klaus Frueh, Jay Parrish, Lawrence Corey, and Louis Picker in April 7, 2016 and is headquartered in San Francisco, CA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
SATO VICKI L	Director	Jun 30	Sale	24.66	18,000	443,916	1,315,351	Jul 03 04:15 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jun 30	Sale	25.11	700	17,577	16,684,041	Jul 05 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jun 29	Sale	25.18	89,942	2,264,731	16,684,741	Jun 30 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jun 28	Sale	25.10	7,010	175,922	16,774,683	Jun 30 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jun 20	Sale	25.18	9,902	249,302	16,781,693	Jun 22 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jun 16	Sale	25.43	128,144	3,258,980	16,791,595	Jun 20 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jun 15	Sale	25.85	55,182	1,426,680	16,919,739	Jun 20 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jun 14	Sale	26.13	57,248	1,495,618	16,974,921	Jun 15 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jun 13	Sale	27.09	106,854	2,894,180	17,032,169	Jun 15 09:00 PM
Pang Phillip	Chief Medical Officer	Jun 07	Option Exercise	1.53	5,000	7,650	193,000	Jun 08 04:30 PM
Pang Phillip	Chief Medical Officer	Jun 07	Sale	25.95	5,000	129,727	188,000	Jun 08 04:30 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jun 05	Sale	27.32	5,197	141,998	17,139,023	Jun 06 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jun 02	Sale	27.32	34,365	938,732	17,144,220	Jun 06 09:00 PM
Ramasastry Saira	Director	Jun 01	Sale	25.67	3,500	89,845	10,619	Jun 02 12:19 PM
Rice Steven J.	Chief Administrative Officer	Jun 01	Sale	25.67	2,500	64,175	106,840	Jun 02 12:20 PM
SVF Endurance (Cayman) Ltd	10% Owner	May 24	Sale	26.15	104,384	2,729,599	17,178,585	May 25 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	May 23	Sale	26.66	170,067	4,533,230	17,282,969	May 25 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	May 22	Sale	25.72	91,896	2,363,905	17,453,036	May 23 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	May 19	Sale	25.38	91,651	2,326,231	17,544,932	May 23 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	May 05	Sale	25.10	136	3,414	17,636,583	May 09 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	May 04	Sale	25.55	114,332	2,921,160	17,636,719	May 05 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	May 03	Sale	25.51	83,674	2,134,691	17,751,051	May 05 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	May 01	Sale	25.30	3,075	77,812	17,834,725	May 03 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Apr 25	Sale	25.30	961	24,313	17,837,800	Apr 26 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Apr 24	Sale	25.42	66,038	1,678,633	17,838,761	Apr 26 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Apr 21	Sale	25.78	305,393	7,872,247	17,904,799	Apr 24 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Apr 20	Sale	25.06	6,590	165,147	18,210,192	Apr 24 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Apr 19	Sale	25.12	76,114	1,911,968	18,216,782	Apr 20 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Apr 18	Sale	25.12	6,953	174,661	18,292,896	Apr 20 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Apr 17	Sale	25.06	10,524	263,741	18,299,849	Apr 18 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Apr 14	Sale	25.11	9,565	240,152	18,310,373	Apr 18 09:00 PM
HANLY ANN M.	Chief Technology Officer	Mar 30	Sale	22.77	2,627	59,817	114,576	Mar 31 02:40 PM
SATO VICKI L	Director	Mar 08	Sale	22.59	17,935	405,062	1,327,324	Mar 09 02:36 PM
Friedl-Naderer Johanna	EVP & Chief Operating Officer	Mar 03	Sale	22.82	1,482	33,819	148,518	Mar 07 02:04 PM
Sigal Charles Elliott	Director	Mar 01	Buy	22.73	2,500	56,816	10,000	Mar 02 04:27 PM
SCANGOS GEORGE A	President and CEO	Feb 24	Sale	23.33	15,119	352,682	168,489	Feb 24 08:34 PM
SCANGOS GEORGE A	President and CEO	Feb 23	Sale	25.97	12,631	328,065	183,608	Feb 24 08:34 PM
Pang Phillip	Chief Medical Officer	Feb 23	Sale	25.97	2,878	74,750	198,320	Feb 24 08:29 PM
HANLY ANN M.	Chief Technology Officer	Feb 23	Sale	25.97	2,302	59,790	117,203	Feb 24 08:35 PM
Horn Howard	CFO	Feb 23	Sale	25.97	2,248	58,387	230,712	Feb 24 08:36 PM
Rice Steven J.	Chief Administrative Officer	Feb 23	Sale	25.97	1,795	46,622	108,414	Feb 24 08:28 PM
SVF Endurance (Cayman) Ltd	10% Owner	Feb 21	Sale	28.43	74,477	2,117,336	18,319,938	Feb 23 09:00 PM
SCANGOS GEORGE A	President and CEO	Feb 21	Sale	28.30	17,856	505,318	196,239	Feb 21 07:29 PM
SCANGOS GEORGE A	President and CEO	Feb 17	Sale	25.29	9,894	250,199	214,095	Feb 21 07:29 PM
Pang Phillip	Chief Medical Officer	Feb 17	Sale	25.29	2,802	70,857	141,198	Feb 21 07:24 PM
Horn Howard	CFO	Feb 17	Sale	25.29	2,424	61,298	232,960	Feb 21 07:22 PM
Rice Steven J.	Chief Administrative Officer	Feb 17	Sale	25.29	1,981	50,096	37,209	Feb 21 07:25 PM
SVF Endurance (Cayman) Ltd	10% Owner	Feb 15	Sale	26.75	38,964	1,042,384	18,394,415	Feb 17 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Feb 14	Sale	26.81	38,907	1,043,108	18,433,379	Feb 15 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Feb 13	Sale	26.02	79,050	2,056,585	18,472,286	Feb 15 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Feb 10	Sale	26.13	97,221	2,540,300	18,551,336	Feb 13 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Feb 09	Sale	26.38	137,050	3,615,729	18,648,557	Feb 13 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Feb 08	Sale	27.88	81,914	2,284,153	18,785,607	Feb 09 09:00 PM
SATO VICKI L	Director	Feb 08	Sale	28.38	17,915	508,343	1,345,259	Feb 09 11:27 AM
SVF Endurance (Cayman) Ltd	10% Owner	Feb 07	Sale	29.33	63,508	1,862,396	18,867,521	Feb 09 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Feb 06	Sale	29.92	45,249	1,353,849	18,931,029	Feb 07 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Feb 03	Sale	30.40	68,786	2,091,135	18,976,278	Feb 07 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Feb 02	Sale	29.70	86,801	2,578,016	19,045,064	Feb 03 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Feb 01	Sale	29.02	61,834	1,794,159	19,131,865	Feb 03 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jan 31	Sale	29.47	73,883	2,177,232	19,193,699	Feb 01 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jan 30	Sale	29.46	78,930	2,325,106	19,267,582	Feb 01 09:00 PM
Pang Phillip	Chief Medical Officer	Jan 24	Sale	30.00	30,000	900,057	144,000	Jan 25 08:01 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jan 23	Sale	28.34	36,512	1,034,707	19,346,512	Jan 25 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jan 20	Sale	27.41	144,358	3,956,801	19,383,024	Jan 23 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jan 19	Sale	26.56	69,839	1,854,610	19,527,382	Jan 23 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jan 18	Sale	26.31	102,467	2,696,409	19,597,221	Jan 19 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jan 17	Sale	26.24	88,372	2,318,749	19,699,688	Jan 19 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jan 13	Sale	26.54	94,199	2,499,749	19,788,060	Jan 17 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jan 12	Sale	26.61	117,479	3,126,129	19,882,259	Jan 17 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jan 11	Sale	26.24	79,065	2,074,607	19,999,738	Jan 12 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jan 10	Sale	26.41	70,575	1,863,886	20,078,803	Jan 12 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jan 09	Sale	25.85	34,801	899,574	20,149,378	Jan 10 09:00 PM
SATO VICKI L	Director	Jan 09	Sale	25.83	17,915	462,784	1,363,174	Jan 11 11:40 AM
SVF Endurance (Cayman) Ltd	10% Owner	Jan 06	Sale	26.13	66,179	1,729,399	20,184,179	Jan 10 09:00 PM
Sigal Charles Elliott	Director	Jan 05	Buy	24.96	2,500	62,396	7,500	Jan 09 11:51 AM
Sigal Charles Elliott	Director	Jan 04	Buy	25.25	2,500	63,136	5,000	Jan 05 05:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jan 04	Sale	25.47	1,000	25,468	20,250,358	Jan 05 09:00 PM
Sigal Charles Elliott	Director	Jan 03	Buy	25.60	2,500	63,992	2,500	Jan 05 05:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Jan 03	Sale	25.58	8,177	209,145	20,251,358	Jan 05 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Dec 29	Sale	25.55	44,169	1,128,461	20,259,535	Jan 03 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Dec 27	Sale	25.59	6,850	175,304	20,303,704	Dec 29 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Dec 23	Sale	25.76	80,081	2,063,115	20,310,554	Dec 27 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Dec 22	Sale	26.07	95,144	2,480,399	20,390,635	Dec 27 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Dec 21	Sale	26.13	111,730	2,919,291	20,485,779	Dec 22 09:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Dec 20	Sale	25.53	104,026	2,656,294	20,597,509	Dec 22 09:00 PM
SATO VICKI L	Director	Dec 08	Sale	25.81	17,915	462,366	1,381,089	Dec 09 03:43 PM
SVF Endurance (Cayman) Ltd	10% Owner	Dec 05	Sale	27.25	8,831	240,644	20,701,535	Dec 06 09:30 PM
SVF Endurance (Cayman) Ltd	10% Owner	Dec 02	Sale	27.47	88,462	2,430,414	20,710,366	Dec 06 09:30 PM
SVF Endurance (Cayman) Ltd	10% Owner	Dec 01	Sale	27.48	46,376	1,274,334	20,798,828	Dec 02 05:51 PM
SVF Endurance (Cayman) Ltd	10% Owner	Nov 30	Sale	27.85	165,953	4,621,607	20,845,204	Dec 02 05:51 PM
SVF Endurance (Cayman) Ltd	10% Owner	Nov 29	Sale	27.39	71,126	1,948,205	21,011,157	Nov 30 08:50 PM
SVF Endurance (Cayman) Ltd	10% Owner	Nov 28	Sale	27.46	37,989	1,043,180	21,082,283	Nov 30 08:50 PM
SVF Endurance (Cayman) Ltd	10% Owner	Nov 25	Sale	27.21	17,264	469,671	21,120,272	Nov 28 05:04 PM
SVF Endurance (Cayman) Ltd	10% Owner	Nov 23	Sale	27.30	39,729	1,084,745	21,137,536	Nov 28 05:04 PM
SVF Endurance (Cayman) Ltd	10% Owner	Nov 22	Sale	27.27	65,213	1,778,195	21,177,265	Nov 23 04:30 PM
SVF Endurance (Cayman) Ltd	10% Owner	Nov 21	Sale	27.13	720	19,535	21,242,478	Nov 22 06:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Nov 18	Sale	27.21	25,259	687,282	21,243,198	Nov 22 06:00 PM
SVF Endurance (Cayman) Ltd	10% Owner	Nov 17	Sale	27.18	73,030	1,984,700	21,268,457	Nov 18 04:30 PM
SVF Endurance (Cayman) Ltd	10% Owner	Nov 16	Sale	27.54	137,001	3,772,909	21,341,487	Nov 18 04:30 PM
SVF Endurance (Cayman) Ltd	10% Owner	Nov 15	Sale	27.72	87,800	2,434,046	21,478,488	Nov 16 09:00 PM

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