3 Artificial Intelligence Stocks to Buy and Hold Through 2035

By Geoffrey Seiler | October 27, 2025, 5:45 AM

Key Points

  • Nvidia has created a wide moat by building a strong ecosystem around its chips.

  • ASML has a monopoly on the technology used to make advanced chips.

  • TSMC has become an invaluable parter to advanced chipmakers.

If you're looking for artificial intelligence (AI) stocks to hold for the next decade, you're going to want to find ones with leadership positions and strong moats. Let's look at three stocks that fit that bill.

Nvidia

When looking for market leaders with wide moats, it would be foolish not to start with Nvidia (NASDAQ: NVDA). The company captured an incredible 94% market share in its fiscal second quarter with its graphics processing units (GPUs), which are the primary chips being used to power AI infrastructure.

Where to invest $1,000 right now? Our analyst team just revealed what they believe are the 10 best stocks to buy right now, when you join Stock Advisor. See the stocks »

Nvidia's moat comes not from having the most powerful chips, but from the ecosystem it has designed around them. This starts with its CUDA software platform, which it created as a way to let developers easily program its chips for tasks outside their original purpose. GPUs were actually developed to help speed up graphics rendering in video games, hence the name, but early on, Nvidia saw they had potential beyond this market.

While other markets were admittedly slow to develop for GPUs, the company smartly seeded CUDA into universities and research labs that were doing early work on AI. This led to most foundational AI code being written on CUDA for its chips, and most developers having been trained on CUDA. This dynamic not only helps its chips' performance, but also makes it extremely difficult to switch.

Nvidia didn't stop there, though. It created a proprietary interconnect system called NVLink that allows its chips to essentially act as a single unit, making them more powerful. Through its acquisition of Mellanox, meanwhile, it added important networking components, which now let it provide end-to-end solutions it calls AI factories. Networking has actually been a huge growth driver for the company, with its data center networking revenue nearly doubling last quarter.

With AI infrastructure spending expected to continue to rise over the next decade, Nvidia remains very well positioned to be a big winner.

ASML

Perhaps no stock has built as wide a moat in the tech space as ASML (NASDAQ: ASML). The company has a true monopoly on extreme ultraviolet lithography (EUV), which is the technology used to make advanced chips. Without EUV, there would be no Nvidia GPUs powering the AI revolution, or even smartphones.

Semiconductor equipment manufacturing can be a lumpy business quarter to quarter because ASML's machines are pricey and it only has a handful of customers for its most advanced machines. However, over the next 10 years, ASML is poised to see strong growth, both from the continued proliferation of advanced chips and the introduction of its newest technology, high numerical aperture (high-NA) EUV.

AI should continue to power chip growth over the next decade, but new applications such as robotaxis, robotics, and quantum computing could also add to this growth during this time. Meanwhile, to shrink node sizes even further, foundries will eventually need to turn to ASML's high-NA EUV platform, which costs nearly double its EUV machines. That makes ASML an intriguing stock to own over the next decade.

The letters AI on a computer chip.

Image source: Getty Images.

Taiwan Semiconductor Manufacturing

Foundry Taiwan Semiconductor Manufacturing (NYSE: TSM) is another company with a wide moat that looks poised to benefit from increasing chip demand. Today, most chipmakers don't actually manufacture their own chips. Not only is it very capital-intensive to build a fab, but it is also very technically challenging to produce advanced chips with high yields at scale.

TSMC's ability to shrink nodes (the amount of transistors that fit on a chip) while maintaining high yields has set it apart in the industry. With rivals struggling with yields, TSMC has become the go-to partner for chipmakers making advanced chips. The keyword is "partner," as companies like Nvidia and Apple rely on TSMC for both their chip roadmaps and to build out their future capacity needs. Its importance in the semiconductor ecosystem should not be underestimated, as it has given it strong pricing power and allowed it to expand its gross margin.

As chip demand continued to grow over the next decade, TSMC is one of the best stocks to own.

Should you invest $1,000 in Nvidia right now?

Before you buy stock in Nvidia, consider this:

The Motley Fool Stock Advisor analyst team just identified what they believe are the 10 best stocks for investors to buy now… and Nvidia wasn’t one of them. The 10 stocks that made the cut could produce monster returns in the coming years.

Consider when Netflix made this list on December 17, 2004... if you invested $1,000 at the time of our recommendation, you’d have $590,357!* Or when Nvidia made this list on April 15, 2005... if you invested $1,000 at the time of our recommendation, you’d have $1,141,748!*

Now, it’s worth noting Stock Advisor’s total average return is 1,033% — a market-crushing outperformance compared to 193% for the S&P 500. Don’t miss out on the latest top 10 list, available when you join Stock Advisor.

See the 10 stocks »

*Stock Advisor returns as of October 20, 2025

Geoffrey Seiler has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends ASML, Apple, Nvidia, and Taiwan Semiconductor Manufacturing. The Motley Fool has a disclosure policy.

Latest News

8 min
24 min
28 min
37 min
45 min
53 min
54 min
58 min
59 min
1 hour
1 hour
1 hour
1 hour
1 hour
1 hour