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DNLI Denali Therapeutics Inc. daily Stock Chart
Denali Therapeutics Inc.
Index- P/E- EPS (ttm)-2.16 Insider Own2.60% Shs Outstand105.72M Perf Week-6.82%
Market Cap4.34B Forward P/E- EPS next Y-2.15 Insider Trans-61.22% Shs Float83.97M Perf Month18.25%
Income-215.80M PEG- EPS next Q2.98 Inst Own90.00% Short Float10.87% Perf Quarter75.59%
Sales27.70M P/S156.57 EPS this Y-428.30% Inst Trans0.20% Short Ratio13.08 Perf Half Y73.88%
Book/sh4.75 P/B8.66 EPS next Y-263.00% ROA-34.50% Target Price35.82 Perf Year170.48%
Cash/sh5.21 P/C7.89 EPS next 5Y- ROE-45.90% 52W Range12.39 - 45.82 Perf YTD136.17%
Dividend- P/FCF- EPS past 5Y- ROI-53.90% 52W High-10.21% Beta-
Dividend %- Quick Ratio9.60 Sales past 5Y- Gross Margin- 52W Low232.04% ATR2.22
Employees276 Current Ratio9.60 Sales Q/Q38.10% Oper. Margin- RSI (14)56.81 Volatility6.02% 5.44%
OptionableYes Debt/Eq0.00 EPS Q/Q9.00% Profit Margin- Rel Volume0.52 Prev Close40.92
ShortableYes LT Debt/Eq0.00 Earnings- Payout- Avg Volume697.93K Price41.14
Recom1.90 SMA203.16% SMA5014.46% SMA20056.15% Volume360,743 Change0.54%
Oct-16-20Downgrade BTIG Research Buy → Neutral
Sep-14-20Resumed JP Morgan Overweight $35
Aug-20-20Reiterated H.C. Wainwright Buy $28 → $45
Mar-13-20Upgrade Evercore ISI In-line → Outperform $20
Feb-28-20Upgrade Wedbush Neutral → Outperform $24
Feb-24-20Initiated Jefferies Buy $35
Feb-19-20Initiated Stifel Hold $26
Jan-27-20Upgrade Goldman Neutral → Buy $20 → $37
Sep-26-19Initiated Wedbush Neutral $19
Sep-13-19Initiated Nomura Buy
Aug-09-19Initiated BTIG Research Buy $30
Jun-26-19Initiated H.C. Wainwright Buy $28
Nov-15-18Initiated Cantor Fitzgerald Overweight $25
Nov-12-18Initiated Janney Buy
Mar-12-18Downgrade Evercore ISI Outperform → In-line
Jan-02-18Initiated Morgan Stanley Overweight
Jan-02-18Initiated JP Morgan Overweight $24
Jan-02-18Initiated Goldman Neutral $19
Jan-02-18Initiated Evercore ISI Outperform $23
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Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutic candidates for neurodegenerative diseases in the United States. The company offers leucine-rich repeat kinase 2 (LRRK2) inhibitor product candidates, including DNL201 that has completed Phase 1b clinical trials and DNL151, which are in Phase 1 and Phase 1b clinical trials for Parkinson's disease. It is also developing receptor interacting serine/threonine protein kinase 1 (RIPK1) product candidates, such as DNL747, a selective and brain-penetrant small molecule RIPK1 inhibitor product candidate that is in Phase 1b clinical trial for Alzheimer's disease and amyotrophic lateral sclerosis (ALS). In addition, the company develops enzyme transport vehicle: iduronate 2-sulfatase, an enzyme replacement therapy program for MPS II, a lysosomal storage disorder; antibody transport vehicle (ATV): alpha-synuclein (aSyn) program, a protein that spreads throughout the brain in Parkinson's disease; ATV: triggering receptor expressed in myeloid cells 2, a therapeutic candidate designed to rescue microglial function in Alzheimer's disease; and ATV: Tau, a therapeutic targeting the spreading of Tau. Further, it has various seed programs under the research, discovery, and preclinical stages of development. Denali Therapeutics Inc. has collaboration agreement with Takeda Pharmaceutical Company and Genentech, Inc., Sanofi, F-star Gamma Limited, F-star Biotechnologische Forschungs-Und Entwicklungsges M.B.H, F-star Biotechnology Limited, SIRION Biotech GmbH, Genzyme Corporation, Harvard University, the Michael J. Fox Foundation, Centogene, and MedGenome Labs Private Ltd; and a research and option agreement with Secarna Pharmaceuticals GmbH & Co. KG. to develop antisense therapies in the field of neurodegenerative diseases. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.
Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total SEC Form 4
Ho CaroleChief Medical OfficerOct 09Option Exercise5.2830,000158,400196,617Oct 13 06:45 PM
Ho CaroleChief Medical OfficerOct 09Sale41.2230,0001,236,614166,617Oct 13 06:45 PM
Ho CaroleChief Medical OfficerOct 08Option Exercise5.2822,906120,944189,523Oct 13 06:45 PM
Ho CaroleChief Medical OfficerOct 08Sale40.1222,906918,989166,617Oct 13 06:45 PM
Ho CaroleChief Medical OfficerSep 10Sale31.003,689114,359165,141Sep 14 09:38 PM
BRATTON DOUGLAS K10% OwnerAug 12Sale31.651,443,24745,678,76812,201,634Aug 14 04:50 PM
BRATTON DOUGLAS K10% OwnerJun 30Sale24.0145,3451,088,601448,035Jun 30 07:17 PM
BRATTON DOUGLAS K10% OwnerJun 29Sale24.0182,5781,982,373493,380Jun 30 07:17 PM
BRATTON DOUGLAS K10% OwnerJun 26Sale23.94122,0772,922,078575,958Jun 30 07:17 PM
BRATTON DOUGLAS K10% OwnerJun 23Sale25.7720,024515,969698,035Jun 23 05:41 PM
BRATTON DOUGLAS K10% OwnerJun 22Sale24.7890,0562,231,902718,059Jun 23 05:41 PM
BRATTON DOUGLAS K10% OwnerJun 19Sale24.54144,9203,556,503808,115Jun 23 05:41 PM
Tessier-Lavigne MarcDirectorJun 16Sale26.10400,00010,440,0002,739,043Jun 18 09:41 PM
BRATTON DOUGLAS K10% OwnerJun 05Sale25.751,922,85549,513,51613,644,881Jun 09 04:10 PM
Krognes Steve E.CFO and TreasurerMar 30Sale19.481,42827,8171,006,488Apr 01 06:19 PM
Schuth Alexander O.COO and SecretaryMar 30Sale19.491,42727,81228,662Apr 01 06:19 PM
Watts Ryan J.President and CEOMar 30Sale19.484,80793,64022,013Apr 01 06:17 PM
Ho CaroleChief Medical OfficerMar 30Sale19.481,42827,8172,822Apr 01 06:18 PM
BRATTON DOUGLAS K10% OwnerFeb 26Sale20.253,894,76478,868,97115,567,736Feb 28 04:25 PM
Ho CaroleChief Medical OfficerDec 23Sale20.013,46469,3150Dec 23 07:35 PM
Ho CaroleChief Medical OfficerDec 20Sale20.0086017,2003,464Dec 23 07:35 PM
Ho CaroleChief Medical OfficerDec 19Sale20.002,56651,3204,324Dec 23 07:35 PM
Schuth Alexander O.COO and SecretaryDec 04Option Exercise5.283,12116,47928,960Dec 05 05:16 PM
Schuth Alexander O.COO and SecretaryDec 04Sale18.002,65647,808580,710Dec 05 05:16 PM
Schuth Alexander O.COO and SecretaryDec 04Sale18.003,12156,17825,839Dec 05 05:16 PM
Watts Ryan J.President and CEODec 04Sale18.0018,755337,5902,429,304Dec 05 04:29 PM
Schuth Alexander O.COO and SecretaryDec 03Option Exercise5.287113,75426,550Dec 05 05:16 PM
Watts Ryan J.President and CEODec 03Sale18.022,51345,2842,448,059Dec 05 04:29 PM
Schuth Alexander O.COO and SecretaryDec 03Sale18.011,01218,226583,366Dec 05 05:16 PM
Schuth Alexander O.COO and SecretaryDec 03Sale18.0171112,80525,839Dec 05 05:16 PM
Schuth Alexander O.COO and SecretaryNov 26Sale18.022294,127584,378Nov 26 05:08 PM
Watts Ryan J.President and CEONov 25Sale18.0242,185760,1742,450,572Nov 26 06:17 PM
Schuth Alexander O.COO and SecretaryNov 25Sale18.0214,125254,533584,607Nov 26 05:08 PM
Schuth Alexander O.COO and SecretaryNov 22Sale18.0064611,628598,732Nov 26 05:08 PM
Watts Ryan J.President and CEONov 22Sale18.001,30023,4002,492,757Nov 26 06:17 PM
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