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Charles River Laboratories International, Inc., a non-clinical contract research organization, provides drug discovery, non-clinical development, and safety testing services in the United States, Europe, Canada, the Asia Pacific, and internationally. It operates through three segments: Research Models and Services (RMS), Discovery and Safety Assessment (DSA), and Manufacturing Solutions (Manufacturing). The RMS segment produces and sells rodent research model strains and purpose-bred rats and mice for use by researchers. This segment also provides a range of services to assist its clients in supporting the use of research models in research and screening non-clinical drug candidates, including research models, genetically engineered models and services, insourcing solutions, and research animal diagnostic services. The DSA segment offers early and in vivo discovery services for the identification and validation of novel targets, chemical compounds, and antibodies through delivery of non-clinical drug and therapeutic candidates ready for safety assessment; and safety assessment services, such as toxicology, pathology, safety pharmacology, bioanalysis, drug metabolism, and pharmacokinetics services. The Manufacturing segment provides in vitro methods for conventional and rapid quality control testing of sterile and non-sterile pharmaceuticals and consumer products. This segment also offers specialized testing of biologics that are outsourced by pharmaceutical and biotechnology companies; and avian vaccine services that provide specific-pathogen-free (SPF) fertile chicken eggs, SPF chickens, and diagnostic products used to manufacture vaccines. The company also provides contract vivarium operation services to biopharmaceutical clients. Charles River Laboratories International, Inc. was founded in 1947 and is headquartered in Wilmington, Massachusetts. |
Insider Trading |
Relationship |
Date |
Transaction |
Cost |
#Shares |
Value ($) |
#Shares Total |
SEC Form 4 |
LaPlume Joseph W | EVP, Corp Strategy & Develop | Aug 05 | Sale | 226.13 | 200 | 45,227 | 20,766 | Aug 08 03:03 PM | MASSARO GEORGE | Director | May 09 | Sale | 230.96 | 178 | 41,110 | 4,677 | May 11 03:52 PM | Smith David Ross | Corporate Executive VP & CFO | Mar 03 | Option Exercise | 136.60 | 8,965 | 1,224,594 | 34,784 | Mar 04 04:13 PM | Smith David Ross | Corporate Executive VP & CFO | Mar 03 | Sale | 282.53 | 8,965 | 2,532,921 | 25,819 | Mar 04 04:13 PM | FOSTER JAMES C | Chairman, President and CEO | Feb 23 | Option Exercise | 109.34 | 20,296 | 2,219,165 | 235,318 | Feb 25 04:20 PM | FOSTER JAMES C | Chairman, President and CEO | Feb 23 | Sale | 287.83 | 20,296 | 5,841,869 | 215,022 | Feb 25 04:20 PM | LaPlume Joseph W | EVP, Corp Strategy & Develop | Feb 23 | Sale | 292.75 | 395 | 115,636 | 19,852 | Feb 24 06:37 PM | FOSTER JAMES C | Chairman, President and CEO | Feb 22 | Option Exercise | 144.67 | 17,436 | 2,522,466 | 234,228 | Feb 23 04:49 PM | WALLMAN RICHARD F | Director | Feb 22 | Sale | 288.05 | 3,250 | 936,162 | 0 | Feb 23 04:07 PM | FOSTER JAMES C | Chairman, President and CEO | Feb 22 | Sale | 288.67 | 17,436 | 5,033,328 | 216,792 | Feb 23 04:49 PM | LaPlume Joseph W | EVP, Corp Strategy & Develop | Feb 22 | Sale | 290.83 | 396 | 115,170 | 20,562 | Feb 23 04:44 PM | LaPlume Joseph W | EVP, Corp Strategy & Develop | Feb 18 | Option Exercise | 88.05 | 743 | 65,421 | 22,418 | Feb 23 04:44 PM | WALLMAN RICHARD F | Director | Feb 18 | Sale | 297.50 | 2,800 | 833,000 | 3,250 | Feb 23 04:07 PM | WALLMAN RICHARD F | Director | Feb 18 | Sale | 295.00 | 1,150 | 339,250 | 17,679 | Feb 23 04:07 PM | LaPlume Joseph W | EVP, Corp Strategy & Develop | Feb 18 | Sale | 291.80 | 1,143 | 333,527 | 21,275 | Feb 23 04:44 PM | FOSTER JAMES C | Chairman, President and CEO | Feb 15 | Sale | 315.46 | 20,000 | 6,309,137 | 218,402 | Feb 17 04:41 PM | Girshick Birgit | Corporate Executive VP | Sep 14 | Sale | 439.90 | 2,344 | 1,031,126 | 27,602 | Sep 15 11:11 AM | Girshick Birgit | Corporate Executive VP | Sep 13 | Sale | 442.19 | 81 | 35,817 | 29,946 | Sep 15 11:11 AM | MASSARO GEORGE | Director | Aug 31 | Option Exercise | 164.24 | 2,539 | 417,005 | 7,394 | Sep 01 02:29 PM | MASSARO GEORGE | Director | Aug 31 | Sale | 442.48 | 2,539 | 1,123,457 | 4,855 | Sep 01 02:29 PM | Creamer Victoria L | EVP & Chief People Officer | Aug 16 | Option Exercise | 145.34 | 6,917 | 1,005,330 | 13,303 | Aug 17 03:01 PM | Creamer Victoria L | EVP & Chief People Officer | Aug 16 | Sale | 415.24 | 6,917 | 2,872,236 | 6,386 | Aug 17 03:01 PM |
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