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KYMR

Kymera Therapeutics Inc

Jun 06 • 04:00PM ET

47.62

Dollar change -0.04
Percentage change -0.08	%

Healthcare • Biotechnology • USA • NASD

Peers: SRRK NRIX ARDX QURE KPTI CRNC RVNC MREO ONCT

| Held by: VTI IWM VB XBI VBK VXF IWO IBB SCHA VTWO

Index	RUT	P/E	-	EPS (ttm)	-3.10	Insider Own	18.27%	Shs Outstand	65.11M	Perf Week	60.66%
Market Cap	3.10B	Forward P/E	-	EPS next Y	-3.86	Insider Trans	-0.63%	Shs Float	53.22M	Perf Month	63.59%
Income	-240.88M	PEG	-	EPS next Q	-0.84	Inst Own	95.94%	Short Float	13.14%	Perf Quarter	44.79%
Sales	58.88M	P/S	52.67	EPS this Y	-15.81%	Inst Trans	2.73%	Short Ratio	8.10	Perf Half Y	1.51%
Book/sh	12.07	P/B	3.94	EPS next Y	-11.91%	ROA	-26.97%	Short Interest	7.00M	Perf Year	49.09%
Cash/sh	7.11	P/C	6.70	EPS next 5Y	-8.41%	ROE	-32.17%	52W Range	19.44 - 53.27	Perf YTD	18.37%
Dividend Est.	-	P/FCF	-	EPS past 5Y	-26.36%	ROI	-28.03%	52W High	-10.61%	Beta	2.05
Dividend TTM	-	Quick Ratio	8.49	Sales past 5Y	74.20%	Gross Margin	86.55%	52W Low	144.90%	ATR (14)	3.17
Dividend Ex-Date	-	Current Ratio	8.49	EPS Y/Y TTM	-23.89%	Oper. Margin	-472.50%	RSI (14)	78.75	Volatility	3.35% 9.03%
Employees	188	Debt/Eq	0.11	Sales Y/Y TTM	-25.85%	Profit Margin	-409.07%	Recom	1.00	Target Price	62.32
Option/Short	Yes / Yes	LT Debt/Eq	0.09	EPS Q/Q	-19.27%	Payout	-	Rel Volume	1.14	Prev Close	47.66
Sales Surprise	105.88%	EPS Surprise	9.59%	Sales Q/Q	114.83%	Earnings	May 09 BMO	Avg Volume	864.04K	Price	47.62
SMA20	40.49%	SMA50	56.15%	SMA200	20.53%	Trades		Volume	986,842	Change	-0.08%

Date	Action	Analyst	Rating Change	Price Target Change
Jun-03-25	Upgrade	Morgan Stanley	Equal-Weight → Overweight	$79
Jun-03-25	Upgrade	B. Riley Securities	Neutral → Buy	$60
Jun-02-25	Upgrade	BofA Securities	Neutral → Buy	$51
May-20-25	Resumed	Stifel	Buy	$55
Mar-13-25	Initiated	Citigroup	Buy	$52
Dec-10-24	Initiated	BTIG Research	Buy	$60
Dec-06-24	Initiated	BMO Capital Markets	Market Perform	$55
Dec-02-24	Upgrade	Wells Fargo	Equal Weight → Overweight	$57
Nov-18-24	Initiated	Stephens	Overweight	$65
Sep-09-24	Resumed	Leerink Partners	Outperform	$60
Aug-26-24	Upgrade	Wolfe Research	Peer Perform → Outperform	$65
Apr-22-24	Initiated	Oppenheimer	Outperform	$53
Feb-15-24	Initiated	Wolfe Research	Peer Perform
Jan-04-24	Upgrade	JP Morgan	Neutral → Overweight
Jan-03-24	Downgrade	BofA Securities	Buy → Neutral	$45 → $30
Dec-19-23	Downgrade	Wells Fargo	Overweight → Equal Weight	$26
Jun-30-23	Initiated	Truist	Buy	$50
May-05-23	Upgrade	Raymond James	Mkt Perform → Outperform
Dec-06-22	Downgrade	Credit Suisse	Outperform → Neutral	$47 → $32
Nov-08-22	Initiated	Raymond James	Mkt Perform

Show Previous Ratings

Today 03:13PM	Kymera Therapeutics Stock Earns 92 RS Rating (Investor's Business Daily)
Jun-05-25 04:16PM	Wall Street Shows Love for Kymera Stock After Biotech's Promising Drug Trial (Barrons.com) +7.68%
Jun-03-25 11:14AM	Kymera Stock Gains on Positive Data on Investigational Dermatitis Drug (Zacks)
02:22AM	Why Kymera Therapeutics, Inc. (KYMR) Skyrocketed On Monday (Insider Monkey)
Jun-02-25 10:29AM	Kymera Therapeutics Says Atopic Dermatitis Potential Matches Sanofi/Regeneron's Blockbuster Dupixent In Early Biomarker Response (Benzinga) +45.51%
07:44AM	Loading…
07:44AM	Kymera Stock Jumps 41%. New Dermatitis Pill Could Challenge Regeneron Blockbuster. (Barrons.com)
07:00AM	Kymera Therapeutics Announces Positive First-in-Human Results from Phase 1 Healthy Volunteer Clinical Trial of KT-621, a First-in-Class, Oral STAT6 Degrader (GlobeNewswire)
May-30-25 04:01PM	Kymera Therapeutics to Announce KT-621 Phase 1 Healthy Volunteer Trial Results on June 2, 2025 (GlobeNewswire)
May-29-25 07:00AM	Kymera Therapeutics to Participate in Upcoming June Investor Conferences (GlobeNewswire) +5.03%
May-19-25 12:15PM	Kymera Therapeutics Presents New Preclinical Data for KT-621, a First-In-Class, Oral STAT6 Degrader at the American Thoracic Society International Conference (GlobeNewswire)
May-10-25 07:00AM	Kymera Therapeutics Inc (KYMR) Q1 2025 Earnings Call Highlights: Strategic Advances and ... (GuruFocus.com)
May-09-25 01:29PM	Kymera' s Q1 Loss Narrower Than Expected, Pipeline Progress Encouraging (Zacks)
08:10AM	Kymera Therapeutics, Inc. (KYMR) Reports Q1 Loss, Tops Revenue Estimates (Zacks)
07:01AM	Kymera Therapeutics Expands Industry Leading Immunology Pipeline with New First-in-Class, Oral IRF5 Degrader Program with Potential to Address Multiple Immuno-Inflammatory Diseases (GlobeNewswire)
07:00AM	Kymera Therapeutics Announces First Quarter 2025 Financial Results and Provides a Business Update (GlobeNewswire)
09:26AM	Loading…
May-08-25 09:26AM	What To Expect From Kymera Therapeutics Inc (KYMR) Q1 2025 Earnings (GuruFocus.com) +5.70%
May-07-25 07:00AM	Kymera Therapeutics to Participate in Fireside Chat at the BofA Securities 2025 Health Care Conference (GlobeNewswire)
Apr-25-25 06:03PM	Why Kymera Therapeutics Stock Crushed it This Week (Motley Fool)
Apr-24-25 07:00AM	Kymera Therapeutics to Unveil New Oral Immunology Program and Report First Quarter 2025 Financial Results on May 9, 2025 (GlobeNewswire) +9.32%
Apr-22-25 07:00AM	Kymera Therapeutics Announces First Patient Dosed in BROADEN Phase 1b Atopic Dermatitis Clinical Trial of KT-621, a First-in-Class Oral STAT6 Degrader (GlobeNewswire) +6.04%
Apr-10-25 10:10AM	Kymera Therapeutics (KYMR) Moves 13.8% Higher: Will This Strength Last? (Zacks) -6.47%
Apr-09-25 07:00AM	Kymera Therapeutics Appoints Noah Goodman as Chief Business Officer (GlobeNewswire) +13.78%
Feb-28-25 02:15AM	Kymera Therapeutics Inc (KYMR) Q4 2024 Earnings Call Highlights: Strategic Collaborations and ... (GuruFocus.com)
Feb-27-25 08:15AM	Kymera Therapeutics, Inc. (KYMR) Reports Q4 Loss, Misses Revenue Estimates (Zacks) -14.45%
07:00AM	Kymera Therapeutics Announces Fourth Quarter and Full Year 2024 Financial Results and Provides a Business Update (GlobeNewswire)
Feb-26-25 07:33AM	What To Expect From Kymera Therapeutics Inc (KYMR) Q4 2024 Earnings (GuruFocus.com)
07:00AM	Kymera Therapeutics to Participate in Upcoming March Investor Conferences (GlobeNewswire)
Feb-20-25 07:00AM	Kymera Therapeutics to Report Fourth Quarter and Full Year 2024 Financial Results on February 27 (GlobeNewswire)
Feb-19-25 09:15AM	NAYA Biosciences Announces Nomination of New Board Members (GlobeNewswire)
Jan-30-25 07:00AM	Kymera Therapeutics to Participate in Upcoming February Investor Conferences (GlobeNewswire)
09:38AM	Loading…
Jan-15-25 09:38AM	Kymera Therapeutics (KYMR) Moves 7.8% Higher: Will This Strength Last? (Zacks) +8.57%
Jan-14-25 01:28PM	Kymera Therapeutics Surges 10% on Bold 2025 Roadmap to Revolutionize Immunology Treatments (GuruFocus.com) +7.79%
07:00AM	Kymera Therapeutics Outlines Key 2025 Objectives and Strategy to Advance Industry Leading Portfolio of Oral Immunology Programs (GlobeNewswire)
Jan-07-25 07:00AM	Kymera Therapeutics to Present at the 43rd Annual J.P. Morgan Healthcare Conference on January 14 (GlobeNewswire)
Dec-27-24 04:25PM	Leerink sees positive readthrough for Kymera Therapeutics from J&J-Kaken deal (TipRanks)
Nov-26-24 07:00AM	Kymera Therapeutics to Participate in Upcoming December Investor Conferences (GlobeNewswire)
Nov-05-24 07:00AM	Kymera Therapeutics to Participate in Upcoming November Investor Conferences (GlobeNewswire)
Nov-01-24 03:07AM	Kymera Therapeutics Inc (KYMR) Q3 2024 Earnings Call Highlights: Strategic Advancements and ... (GuruFocus.com)
12:04AM	U.S. Drugmakers Are Breaking Up With Their Chinese Supply-Chain Partners (The Wall Street Journal)
Oct-31-24 08:40AM	Kymera Therapeutics, Inc. (KYMR) Reports Q3 Loss, Lags Revenue Estimates (Zacks)
07:30AM	Kymera Therapeutics Announces Third Quarter 2024 Financial Results and Provides a Business Update (GlobeNewswire)
Oct-30-24 09:10AM	Kymera Therapeutics Inc (KYMR) Q3 2024: Everything You Need To Know Ahead Of Earnings (GuruFocus.com)
Oct-24-24 10:01AM	Kymera Therapeutics, Inc. (KYMR) Expected to Beat Earnings Estimates: What to Know Ahead of Q3 Release (Zacks)
07:00AM	Kymera Therapeutics Announces Dosing of First Participant in Phase 1 Clinical Trial of KT-621, a First-in-Class Oral STAT6 Degrader, for the Treatment of TH2 Immuno-Inflammatory Diseases (GlobeNewswire)
Oct-23-24 07:15AM	Kymera Therapeutics to Report Third Quarter 2024 Financial Results on October 31 (GlobeNewswire)
07:00AM	Kymera Therapeutics Announces Three Scientific Presentations at the EORTC-NCI-AACR 2024 Symposium (GlobeNewswire)
Oct-09-24 07:00AM	Kymera Therapeutics Announces FDA Clearance of Investigational New Drug Application for KT-621, a First-in-Class, Oral STAT6 Degrader (GlobeNewswire)
Sep-25-24 07:00AM	Kymera Therapeutics Presents Preclinical Data for KT-621, a Potent, Selective, First-In-Class, Oral STAT6 Degrader at the EADV Congress (GlobeNewswire)
Sep-06-24 11:31AM	Why Is Kymera Therapeutics (KYMR) Up 10.9% Since Last Earnings Report? (Zacks)
Aug-28-24 07:00AM	Kymera Therapeutics to Participate in Upcoming September Investor Conferences (GlobeNewswire)
Aug-21-24 11:15AM	Kymera Therapeutics Announces Closing of Upsized $225 Million Public Offering and Full Exercise of Underwriters' Option to Purchase Additional Shares (GlobeNewswire)
Aug-20-24 01:02PM	Kymera (KYMR) to Raise $225 Million Through Offering of Shares (Zacks)
07:44AM	Avidity, Kymera raise fresh funds; Walgreens partners with BARDA (BioPharma Dive)
Aug-19-24 10:45PM	Kymera Therapeutics Announces Pricing of $225 Million Public Offering (GlobeNewswire)
04:01PM	Kymera Therapeutics Announces Proposed Public Offering (GlobeNewswire)
Aug-08-24 09:55AM	Kymera (KYMR) Q2 Loss Narrower Than Expected, Pipeline in Focus (Zacks)
Aug-07-24 08:10AM	Kymera Therapeutics, Inc. (KYMR) Reports Q2 Loss, Tops Revenue Estimates (Zacks)
07:00AM	Kymera Therapeutics Announces Second Quarter 2024 Financial Results and Provides a Business Update (GlobeNewswire)
Jul-31-24 07:00AM	Kymera Therapeutics to Report Second Quarter 2024 Financial Results on August 7 (GlobeNewswire) +7.17%
Jul-10-24 08:10AM	Kymera Therapeutics (KYMR) Surges 23.4%: Is This an Indication of Further Gains? (Zacks) -8.09%
Jul-09-24 01:30PM	Why Kymera Therapeutics Stock Is Soaring Today (Motley Fool) +23.40%
12:22PM	Kymera Therapeutics soars as Sanofi expands phase 2 trials (Investing.com)
10:44AM	Kymera Therapeutics Soars as Sanofi Expands Studies of Its Skin Diseases Drug (Investopedia)
09:59AM	Kymera's (KYMR) Partner SNY to Expand Ongoing HS and AD Studies (Zacks)
07:00AM	Kymera Therapeutics to Present in Fireside Chat at the UBS Virtual Targeted Protein Degradation Day (GlobeNewswire)
Jul-08-24 04:05PM	Kymera Announces Expansion of KT-474 (SAR444656) HS and AD Phase 2 Studies Following Interim Review of Safety and Efficacy (GlobeNewswire) +5.65%
Jun-20-24 08:45AM	Biotechs Race to Develop New Treatments as Global Pancreatic Cancer Market Size Expected to Reach $7.5 Billion by 2033 (GlobeNewswire)
Jun-14-24 07:00AM	Kymera Therapeutics Presents New Clinical Data from the Ongoing Phase 1 Trial of STAT3 Degrader KT-333 at EHA Annual Meeting (GlobeNewswire)
Jun-01-24 08:00AM	Kymera Therapeutics Presents New Clinical Data from Ongoing Phase 1 Trial of MDM2 Degrader KT-253 at ASCO Annual Meeting (GlobeNewswire)
May-29-24 07:00AM	Kymera Therapeutics to Participate in Upcoming June Investor Conferences (GlobeNewswire)
May-23-24 05:00PM	Kymera Therapeutics to Present New Clinical Data from Ongoing Phase 1 Trial of MDM2 Degrader KT-253 at ASCO Annual Meeting (GlobeNewswire)
May-22-24 11:20AM	Kymera Therapeutics Presents New Preclinical Data for KT-621, a First-In-Class, Oral STAT6 Degrader at the ATS Annual Meeting (GlobeNewswire)
May-14-24 10:00AM	Kymera Therapeutics to Present New Clinical Data from the Ongoing Phase 1 Trial of STAT3 Degrader KT-333 at EHA Annual Meeting (GlobeNewswire) -8.52%
May-08-24 07:00AM	Kymera Therapeutics to Participate in Upcoming May Investor Conferences (GlobeNewswire)
May-03-24 12:23PM	Kymera Therapeutics, Inc. (NASDAQ:KYMR) Q1 2024 Earnings Call Transcript (Insider Monkey)
09:57AM	Kymera (KYMR) Q1 Loss Narrower Than Expected, Pipeline in Focus (Zacks)
09:55AM	Wall Street Analysts Predict a 34.41% Upside in Kymera Therapeutics (KYMR): Here's What You Should Know (Zacks)
08:44AM	Oppenheimer Adjusts Kymera Therapeutics Price Target to $52 From $53 (MT Newswires)
03:19AM	Kymera Therapeutics Inc (KYMR) (Q1 2024) Earnings Call Transcript Highlights: Strategic ... (GuruFocus.com)
May-02-24 12:18PM	Kymera Therapeutics Q1 Net Loss Narrows, Collaboration Revenue Rises (MT Newswires)
11:57AM	KYMR Stock Earnings: Kymera Therapeutics Beats EPS, Misses Revenue for Q1 2024 (InvestorPlace)
07:00AM	Kymera Therapeutics Announces First Quarter 2024 Financial Results and Provides a Business Update (GlobeNewswire)
Apr-25-24 10:02AM	Kymera Therapeutics, Inc. (KYMR) Expected to Beat Earnings Estimates: What to Know Ahead of Q1 Release (Zacks) -5.28%
09:20AM	20 Counties with the Highest Cancer Rates in the US (Insider Monkey)
07:00AM	Kymera Therapeutics to Report First Quarter 2024 Financial Results on May 2 (GlobeNewswire)
Apr-08-24 07:00AM	Kymera Therapeutics Announces Scientific Presentations at the American Association for Cancer Research 2024 Annual Meeting (GlobeNewswire)
Mar-08-24 10:00AM	Kymera Therapeutics Presents Preclinical Data for STAT6 and TYK2 First-In-Class, Oral Degrader Immunology Programs at the American Academy of Dermatology Annual Meeting (GlobeNewswire)
Mar-04-24 11:27PM	Insider Sell: CFO Bruce Jacobs Sells 3,934 Shares of Kymera Therapeutics Inc (KYMR) (GuruFocus.com)
Feb-28-24 07:00AM	Kymera Therapeutics to Participate in Upcoming March Investor Conferences (GlobeNewswire)
Feb-23-24 11:59AM	Kymera Therapeutics, Inc. (NASDAQ:KYMR) Q4 2023 Earnings Call Transcript (Insider Monkey)
Feb-22-24 11:24PM	Q4 2023 Kymera Therapeutics Inc Earnings Call (Thomson Reuters StreetEvents)
07:35AM	Kymera Therapeutics Inc (KYMR) Reports Q4 and Full Year 2023 Financial Results (GuruFocus.com)
07:00AM	Kymera Therapeutics Announces Fourth Quarter and Full Year 2023 Financial Results and Provides a Business Update (GlobeNewswire)
Feb-21-24 11:52PM	Director Jeffrey Albers Sells 5,000 Shares of Kymera Therapeutics Inc (KYMR) (GuruFocus.com)
Feb-15-24 10:00AM	Kymera Therapeutics, Inc. (KYMR) Expected to Beat Earnings Estimates: Should You Buy? (Zacks)
07:00AM	Kymera Therapeutics to Report Fourth Quarter and Full Year 2023 Financial Results on February 22 (GlobeNewswire)
Feb-10-24 02:56AM	Chief Medical Officer Jared Gollob Sells 46,137 Shares of Kymera Therapeutics Inc (GuruFocus.com)
Jan-31-24 07:00AM	Kymera Therapeutics to Present in Fireside Chat at the Guggenheim Healthcare Conference (GlobeNewswire)
Jan-24-24 12:20AM	Director Jeffrey Albers Sells 10,000 Shares of Kymera Therapeutics Inc (GuruFocus.com)
Jan-17-24 08:00AM	INVO Bioscience Files S-4 Registration and Preliminary Joint Proxy Statements in Connection with Merger with NAYA Biosciences, NAYA Announces New Board Directors (GlobeNewswire)

Kymera Therapeutics, Inc. is a biopharmaceutical company, which engages in the discovery and development of small molecule therapeutics that degrade disease-causing proteins. The company was founded by Bruce Lee Booth and Nello Mainolfi in September 2015 and is headquartered in Watertown, MA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Esposito Pamela	Director	Jun 03 '25	Option Exercise	29.55	5,000	147,750	5,000	Jun 03 06:30 PM
Esposito Pamela	Director	Jun 03 '25	Sale	49.04	5,000	245,186	0	Jun 03 06:30 PM
Ridloff Elena	Director	Jun 03 '25	Option Exercise	27.67	12,000	332,040	12,000	Jun 03 06:30 PM
Ridloff Elena	Director	Jun 03 '25	Sale	46.10	12,000	553,200	0	Jun 03 06:30 PM
Mainolfi Nello	Chief Executive Officer	Jun 03 '25	Option Exercise	2.08	30,000	62,400	690,482	Jun 03 06:30 PM
Mainolfi Nello	Chief Executive Officer	Jun 03 '25	Sale	49.00	30,000	1,470,000	660,482	Jun 03 06:30 PM
Albers Jeffrey W.	Director	Jun 03 '25	Option Exercise	10.34	6,349	65,649	6,349	Jun 03 06:30 PM
Albers Jeffrey W.	Director	Jun 03 '25	Sale	49.00	6,349	311,101	0	Jun 03 06:30 PM
Mainolfi Nello	Officer	Jun 03 '25	Proposed Sale	49.00	30,000	1,470,000		Jun 03 04:31 PM
JEFFREY ALBERS	Director	Jun 03 '25	Proposed Sale	43.13	6,349	273,832		Jun 03 04:25 PM
PAMELA ESPOSITO	Director	Jun 03 '25	Proposed Sale	43.13	5,000	215,650		Jun 03 04:25 PM
ELENA RIDLOFF	Director	Jun 03 '25	Proposed Sale	43.13	12,000	517,560		Jun 03 04:24 PM
Chadwick Jeremy G	Chief Operating Officer	May 23 '25	Sale	29.30	2,575	75,436	66,420	May 23 04:30 PM
Chadwick Jeremy G	Officer	May 23 '25	Proposed Sale	30.17	2,575	77,688		May 23 04:20 PM
Jacobs Bruce N.	Chief Financial Officer	Mar 31 '25	Option Exercise	2.08	25,000	52,000	226,886	Apr 01 08:00 AM
Chiniara Ellen	Chief Legal Officer	Mar 03 '25	Sale	30.45	2,241	68,239	80,085	Mar 03 06:30 PM
Chadwick Jeremy G	Chief Operating Officer	Mar 03 '25	Sale	30.45	1,383	42,113	67,800	Mar 03 06:30 PM
Jacobs Bruce N.	Chief Financial Officer	Mar 03 '25	Sale	30.45	7,035	214,219	201,886	Mar 03 06:30 PM
Gollob Jared	Chief Medical Officer	Mar 03 '25	Sale	30.45	5,740	174,786	120,000	Mar 03 06:30 PM
Gollob Jared	Officer	Mar 03 '25	Proposed Sale	31.35	5,740	179,949		Mar 03 06:00 PM
Chiniara Ellen	Officer	Mar 03 '25	Proposed Sale	31.35	2,241	70,255		Mar 03 06:00 PM
Chadwick Jeremy G	Officer	Mar 03 '25	Proposed Sale	31.35	1,383	43,357		Mar 03 06:00 PM
Jacobs Bruce N.	Officer	Mar 03 '25	Proposed Sale	31.35	7,035	220,547		Mar 03 06:00 PM
Mainolfi Nello	Chief Executive Officer	Jan 10 '25	Option Exercise	2.08	10,000	20,800	659,959	Jan 13 07:00 AM
Jacobs Bruce N.	Chief Financial Officer	Jan 10 '25	Option Exercise	2.08	10,000	20,800	178,921	Jan 13 07:00 AM
Chiniara Ellen	Chief Legal Officer	Jan 06 '25	Sale	41.75	3,129	130,645	54,826	Jan 06 05:00 PM
Chiniara Ellen	Officer	Jan 06 '25	Proposed Sale	41.59	3,129	130,135		Jan 06 04:30 PM
Esposito Pamela	Director	Dec 02 '24	Option Exercise	29.55	2,500	73,875	2,500	Dec 02 07:50 PM
Esposito Pamela	Director	Dec 02 '24	Sale	49.00	2,500	122,500	0	Dec 02 07:50 PM
PAMELA ESPOSITO	Director	Dec 02 '24	Proposed Sale	46.85	2,500	117,125		Dec 02 04:41 PM
Esposito Pamela	Director	Sep 17 '24	Option Exercise	23.86	13,500	322,075	13,500	Sep 17 06:20 PM
Esposito Pamela	Director	Sep 17 '24	Sale	48.28	13,500	651,766	0	Sep 17 06:20 PM
PAMELA ESPOSITO	Director	Sep 17 '24	Proposed Sale	48.48	13,500	654,480		Sep 17 04:40 PM
Albers Jeffrey W.	Director	Aug 26 '24	Option Exercise	10.34	5,000	51,700	5,000	Aug 26 06:31 PM
Albers Jeffrey W.	Director	Aug 26 '24	Sale	49.10	5,000	245,508	0	Aug 26 06:31 PM
JOANNA HOROBIN	Director	Aug 26 '24	Proposed Sale	49.16	12,000	589,896		Aug 26 04:32 PM
JEFFREY ALBERS	Director	Aug 26 '24	Proposed Sale	47.78	5,000	238,900		Aug 26 04:25 PM
BAKER BROS. ADVISORS LP	Director	Aug 20 '24	Buy	46.41	1	46	5,516,986	Aug 22 04:03 PM
Gollob Jared	Chief Medical Officer	Jul 16 '24	Option Exercise	2.08	23,145	48,142	118,885	Jul 16 06:00 PM
Gollob Jared	Chief Medical Officer	Jul 15 '24	Option Exercise	2.08	16,455	34,226	112,195	Jul 16 06:00 PM
Gollob Jared	Chief Medical Officer	Jul 16 '24	Sale	45.81	23,145	1,060,218	95,470	Jul 16 06:00 PM
Gollob Jared	Chief Medical Officer	Jul 15 '24	Sale	45.15	16,455	742,925	95,740	Jul 16 06:00 PM
Booth Bruce	Director	Jul 09 '24	Sale	38.21	453,960	17,346,919	723,246	Jul 09 05:15 PM
Mainolfi Nello	Chief Executive Officer	Jul 01 '24	Option Exercise	5.33	18,773	100,060	649,959	Jul 01 04:30 PM
Jacobs Bruce N.	Chief Financial Officer	Jun 27 '24	Option Exercise	2.08	25,000	52,000	168,554	Jun 28 08:30 AM
Mainolfi Nello	Chief Executive Officer	Jun 18 '24	Option Exercise	2.08	14,413	29,979	631,186	Jun 20 08:30 AM
Booth Bruce	Director	Jun 12 '24	Sale	35.45	16,740	593,378	803,792	Jun 14 06:01 PM
Booth Bruce	Director	Jun 13 '24	Sale	34.98	10,200	356,796	802,022	Jun 14 06:01 PM
Horobin Joanna	Director	Jun 07 '24	Option Exercise	2.08	8,500	17,680	8,500	Jun 07 06:36 PM
Horobin Joanna	Director	Jun 07 '24	Sale	32.99	8,500	280,400	0	Jun 07 06:36 PM

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BPMC

Blueprint Medicines Corp

Jun 06 • 04:00PM ET

127.85

Dollar change -0.05
Percentage change -0.04	%

Healthcare • Biotechnology • USA • NASD

BPMC Blueprint Medicines Corp daily Stock Chart

Peers: INCY EXEL SAGE TXMD GNFT BLUE TVRD DNLI BYSI MGNX

| Held by: IWM VTI XBI VB VXF VBK IWO IBB SCHA VTWO

Index	RUT	P/E	-	EPS (ttm)	-2.46	Insider Own	3.67%	Shs Outstand	64.56M	Perf Week	26.15%
Market Cap	8.26B	Forward P/E	139.19	EPS next Y	0.92	Insider Trans	-5.85%	Shs Float	62.21M	Perf Month	28.11%
Income	-155.73M	PEG	-	EPS next Q	-0.44	Inst Own	106.96%	Short Float	9.11%	Perf Quarter	46.75%
Sales	562.12M	P/S	14.69	EPS this Y	34.23%	Inst Trans	3.70%	Short Ratio	2.63	Perf Half Y	32.45%
Book/sh	5.30	P/B	24.13	EPS next Y	230.52%	ROA	-13.94%	Short Interest	5.67M	Perf Year	25.48%
Cash/sh	8.92	P/C	14.33	EPS next 5Y	-	ROE	-47.71%	52W Range	73.04 - 128.24	Perf YTD	46.58%
Dividend Est.	0.33 (0.26%)	P/FCF	-	EPS past 5Y	31.87%	ROI	-16.74%	52W High	-0.30%	Beta	0.82
Dividend TTM	-	Quick Ratio	2.75	Sales past 5Y	50.22%	Gross Margin	93.65%	52W Low	75.04%	ATR (14)	4.32
Dividend Ex-Date	-	Current Ratio	2.80	EPS Y/Y TTM	48.43%	Oper. Margin	-31.01%	RSI (14)	76.09	Volatility	0.26% 5.75%
Employees	649	Debt/Eq	2.08	Sales Y/Y TTM	99.19%	Profit Margin	-27.70%	Recom	2.74	Target Price	131.53
Option/Short	Yes / Yes	LT Debt/Eq	1.72	EPS Q/Q	-99.46%	Payout	-	Rel Volume	1.43	Prev Close	127.90
Sales Surprise	-3.91%	EPS Surprise	102.06%	Sales Q/Q	55.45%	Earnings	May 01 BMO	Avg Volume	2.15M	Price	127.85
SMA20	19.37%	SMA50	33.61%	SMA200	35.58%	Trades		Volume	3,067,536	Change	-0.04%

Date	Action	Analyst	Rating Change	Price Target Change
Jun-02-25	Downgrade	Wedbush	Outperform → Neutral	$129
Mar-20-25	Resumed	Morgan Stanley	Equal-Weight	$100
Mar-18-25	Initiated	Wolfe Research	Outperform
Mar-17-25	Initiated	Jefferies	Buy	$135
Mar-07-25	Initiated	Scotiabank	Sector Outperform	$150
Nov-14-24	Initiated	JP Morgan	Overweight	$126
Oct-24-24	Initiated	UBS	Neutral	$88
May-14-24	Initiated	Stephens	Overweight	$140
May-06-24	Upgrade	Leerink Partners	Underperform → Market Perform	$50 → $97
Oct-27-23	Upgrade	Oppenheimer	Perform → Outperform	$85
Aug-21-23	Reiterated	Needham	Buy	$65 → $66
Jul-31-23	Upgrade	Wells Fargo	Equal Weight → Overweight	$55 → $82
Jun-05-23	Downgrade	SVB Securities	Market Perform → Underperform	$48 → $43
Jan-03-23	Upgrade	Wells Fargo	Underweight → Equal Weight	$41
Dec-14-22	Initiated	Needham	Buy	$60
Nov-02-22	Downgrade	Oppenheimer	Outperform → Perform
Sep-14-22	Initiated	Berenberg	Buy	$90
Jul-08-22	Initiated	Oppenheimer	Outperform	$80
Jun-27-22	Initiated	Wells Fargo	Underweight	$40
Jun-10-22	Downgrade	Citigroup	Neutral → Sell	$68 → $41

Show Previous Ratings

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Jun-03-25 02:22AM	Why Blueprint Medicines Corporation (BPMC) Skyrocketed On Monday (Insider Monkey)
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11:58AM	Loading…
11:58AM	Sanofi Signs a $9.5B Agreement to Acquire Blueprint Medicines (Zacks)
11:45AM	M&A is 'lifeblood' of biopharma: Analyst on Sanofi-Blueprint deal (Yahoo Finance Video)
11:43AM	Sanofi to acquire Blueprint Medicines, Boeing upgrade (Yahoo Finance Video)
10:54AM	Sanofi to expand immunology offerings with Blueprint Medicines (Pharmaceutical Technology)
08:54AM	Blueprint Medicines Stock Soars as Biotech Agrees to Over $9B Sanofi Takeover (Investopedia)
08:12AM	Sanofi Expands Rare Immunology Portfolio With Blueprint Buyout (Benzinga)
07:38AM	5 Things to Know Before the Stock Market Opens (Investopedia)
06:50AM	Blueprint Medicines Soars 27% on $9.5 Billion Buyout. Why This Drug Is Key to the Deal. (Barrons.com)
05:11AM	Sanofi to Buy Blueprint Medicines for Up to $9.5 Billion in Boost to Pipeline (The Wall Street Journal)
01:25AM	Sanofi to acquire Blueprint Medicines, expanding portfolio in rare immunological disease and adding early-stage pipeline in immunology (PR Newswire)
01:24AM	Loading…
01:24AM	Sanofi to buy US biopharma group Blueprint for up to $9.5 billion (Reuters)
01:22AM	Sanofi to Acquire Blueprint Medicines for Up to $9.5 Billion (The Wall Street Journal)
May-24-25 06:02AM	Stay Invested: Wells Fargo Suggests 2 Stocks to Ride the Market Recovery (TipRanks)
May-02-25 12:21PM	Blueprint Medicines Stock Up Despite Lower-Than-Expected Q1 Earnings (Zacks) +5.43%
03:03AM	Blueprint Medicines Corp (BPMC) Q1 2025 Earnings Call Highlights: Strong AYVAKIT Revenue Growth ... (GuruFocus.com)
01:22AM	Q1 2025 Blueprint Medicines Corp Earnings Call (Thomson Reuters StreetEvents)
May-01-25 02:01PM	Blueprint Medicines Corporation (BPMC) Q1 2025 Earnings Call Transcript (Seeking Alpha) +10.89%
08:25AM	Blueprint Medicines (BPMC) Reports Q1 Loss, Lags Revenue Estimates (Zacks)
07:22AM	Blueprint Medicines: Q1 Earnings Snapshot (Associated Press Finance)
07:00AM	Blueprint Medicines Reports First Quarter 2025 Results and Raises AYVAKIT/AYVAKYT (avapritinib) Full Year Revenue Guidance (PR Newswire)
Apr-29-25 11:59AM	Corcept Therapeutics to Report Q1 Earnings: What's in the Cards? (Zacks)
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Apr-25-25 11:59AM	CRISPR Therapeutics to Report Q1 Earnings: What's in the Cards? (Zacks)
08:00AM	Blueprint Medicines to Report First Quarter 2025 Financial Results on Thursday, May 1, 2025 (PR Newswire)
10:01AM	Loading…
Apr-24-25 10:01AM	Blueprint Medicines (BPMC) Expected to Beat Earnings Estimates: Should You Buy? (Zacks)
Apr-23-25 08:47PM	Blueprint Medicines Corporation (BPMC): Among Takeover Rumors Hedge Funds Are Buying (Insider Monkey)
Apr-15-25 08:59AM	Adma Biologics (ADMA) Moves 7.8% Higher: Will This Strength Last? (Zacks)
Apr-07-25 05:37AM	Blueprint Medicines Continues Targeting Mast Cells For Potential Billion-Dollar Growth (Seeking Alpha)
Mar-31-25 08:00AM	Blueprint Medicines to Present at 24th Annual Needham Virtual Healthcare Conference (PR Newswire)
Mar-30-25 04:10PM	Is Blueprint Medicines (BPMC) One of the Best Mid Cap Biotech Stocks to Buy? (Insider Monkey)
Mar-29-25 06:04AM	Blueprint Medicines: Strong Business, Ambitious Targets, Expensive Stock (Seeking Alpha)
Mar-25-25 09:18PM	Is Blueprint Medicines Corporation (BPMC) a Promising Biotech Stock According to Wall Street Analysts (InsiderMonkey)
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Mar-18-25 09:45AM	Reddit initiated, Netflix upgraded: Wall Streets top analyst calls (TipRanks)
Feb-28-25 08:00AM	Blueprint Medicines Highlights Leading Portfolio of Mast Cell-Targeted Therapies at 2025 AAAAI / WAO Joint Congress (PR Newswire) +6.80%
Feb-24-25 01:12PM	Blueprint Medicines Corporation (BPMC): Among the Oversold Biotech Stocks to Buy Now (Insider Monkey)
Feb-14-25 02:09AM	Blueprint Medicines Corp (BPMC) Q4 2024 Earnings Call Highlights: Record Growth and Strategic ... (GuruFocus.com)
Feb-13-25 11:23PM	Q4 2024 Blueprint Medicines Corp Earnings Call (Thomson Reuters StreetEvents) -8.08%
08:25AM	Blueprint Medicines (BPMC) Reports Q4 Loss, Misses Revenue Estimates (Zacks)
07:21AM	Blueprint Medicines: Q4 Earnings Snapshot (Associated Press Finance)
07:00AM	Blueprint Medicines Reports Fourth Quarter and Full Year 2024 Results (PR Newswire)
Feb-06-25 10:01AM	Will Blueprint Medicines (BPMC) Report Negative Earnings Next Week? What You Should Know (Zacks)
09:55AM	Should You Buy Blueprint Medicines (BPMC) After Golden Cross? (Zacks)
Feb-05-25 08:00AM	Blueprint Medicines to Report Fourth Quarter and Full Year 2024 Financial Results on Thursday, February 13, 2025 (PR Newswire)
Jan-26-25 03:09AM	Why Blueprint Medical (BPMC) Is Skyrocketing Now (Insider Monkey)
Jan-14-25 04:43AM	Blueprint Medicines (BPMC) Stock Jumps 18.2%: Will It Continue to Soar? (Zacks)
Jan-13-25 11:13AM	Blueprint Medicines Surges Over 10% as 2025 Growth Strategy Ignites Investor (GuruFocus.com) +18.22%
Jan-12-25 04:00PM	Blueprint Medicines Provides 2025 Outlook and Highlights Strategy for Continued Growth (PR Newswire)
Dec-18-24 08:00AM	Blueprint Medicines to Present at the 43rd Annual J.P. Morgan Healthcare Conference (PR Newswire)
Dec-07-24 12:30PM	Blueprint Medicines' Continued Leadership in Redefining the Standard of Care in Systemic Mastocytosis Highlighted at 2024 ASH Annual Meeting (PR Newswire)
Nov-29-24 11:31AM	Blueprint Medicines (BPMC) Up 8.7% Since Last Earnings Report: Can It Continue? (Zacks)
Nov-14-24 03:18PM	Blood Cancer-Focused Blueprint Medicines Could Be 'Attractive Target For Partnerships': Analyst (Benzinga)
Oct-31-24 03:05AM	Blueprint Medicines Corp (BPMC) Q3 2024 Earnings Call Highlights: Record AYVAKIT Revenue and ... (GuruFocus.com)
12:04AM	Q3 2024 Blueprint Medicines Corp Earnings Call (Thomson Reuters StreetEvents)
Oct-30-24 08:10AM	Blueprint Medicines (BPMC) Reports Q3 Loss, Tops Revenue Estimates (Zacks) +7.00%
07:10AM	Blueprint Medicines: Q3 Earnings Snapshot (Associated Press Finance)
07:00AM	Blueprint Medicines Reports Third Quarter 2024 Results and Raises AYVAKIT/AYVAKYT (avapritinib) Full Year Revenue Guidance (PR Newswire)
Oct-23-24 10:01AM	Blueprint Medicines (BPMC) May Report Negative Earnings: Know the Trend Ahead of Next Week's Release (Zacks)
Oct-21-24 12:00PM	Blueprint Medicines (BPMC) Upgraded to Strong Buy: What Does It Mean for the Stock? (Zacks)
Oct-16-24 08:00AM	Blueprint Medicines to Report Third Quarter 2024 Financial Results on Wednesday, October 30, 2024 (PR Newswire)
Oct-15-24 09:55AM	Wall Street Analysts Predict a 41.4% Upside in Blueprint Medicines (BPMC): Here's What You Should Know (Zacks)
Sep-10-24 08:00AM	Blueprint Medicines to Present at Upcoming Investor Conferences (PR Newswire)
Aug-19-24 07:00PM	Insider Sale: CFO Michael Landsittel Sells Shares of Blueprint Medicines Corp (BPMC) (GuruFocus.com)
Aug-09-24 09:55AM	Blueprint Medicines (BPMC) Forms 'Hammer Chart Pattern': Time for Bottom Fishing? (Zacks)
Aug-02-24 10:44AM	Blueprint Medicines (BPMC) Down Despite Q2 Earnings Beat (Zacks)
Aug-01-24 08:05AM	Blueprint Medicines (BPMC) Reports Q2 Loss, Tops Revenue Estimates (Zacks) -7.40%
07:05AM	Blueprint Medicines: Q2 Earnings Snapshot (Associated Press Finance)
07:00AM	Blueprint Medicines Reports Second Quarter 2024 Results and Raises AYVAKIT/AYVAKYT (avapritinib) Full Year Revenue Guidance (PR Newswire)
Jul-25-24 10:02AM	Blueprint Medicines (BPMC) Expected to Beat Earnings Estimates: Should You Buy? (Zacks)
Jul-18-24 08:00AM	Blueprint Medicines to Report Second Quarter 2024 Financial Results on Thursday, August 1, 2024 (PR Newswire)
Jun-25-24 12:39PM	How IBD Stock Of The Day Blueprint Medicines 'Knocked It Out Of The Park' (Investor's Business Daily)
Jun-07-24 09:15PM	Insider Sale: Chief Scientific Officer Percy Carter Sells Shares of Blueprint Medicines Corp (BPMC) (GuruFocus.com)
Jun-06-24 07:01PM	Insider Sale at Blueprint Medicines Corp (BPMC): Chief Medical Officer L. Hewes Sells Shares (GuruFocus.com)
May-30-24 06:01PM	Blueprint Medicines Announces Data Presentations at EAACI and EHA Annual Meetings Highlighting Sustained Clinical Benefits of AYVAKIT/AYVAKYT (avapritinib) (PR Newswire) +5.76%
May-23-24 05:05PM	Blueprint Medicines to Present the First Promising and Most Advanced Clinical Data for a CDK2 Inhibitor in Combination with an Approved CDK4/6 Inhibitor in HR+/HER2- Breast Cancer at the 2024 ASCO Annual Meeting (PR Newswire)
May-14-24 07:50AM	Stephens Starts Blueprint Medicines With Overweight Rating, $140 Price Target (MT Newswires)
May-06-24 05:32PM	Blueprint Medicines Insider Sold Shares Worth $1,050,000, According to a Recent SEC Filing (MT Newswires)
04:01PM	Blueprint Medicines Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (PR Newswire)
11:45AM	Goldman Sachs Adjusts Price Target on Blueprint Medicines to $168 From $121, Maintains Buy Rating (MT Newswires)
07:05AM	Leerink Upgrades Blueprint Medicines to Market Perform, Price Target at $97 (MT Newswires)
May-03-24 10:03AM	Blueprint Medicines Corporation (NASDAQ:BPMC) Q1 2024 Earnings Call Transcript (Insider Monkey)
09:51AM	Blueprint (BPMC) Q1 Earnings and Revenues Beat, Stock Rises (Zacks)
03:05AM	Blueprint Medicines Corp (BPMC) (Q1 2024) Earnings Call Transcript Highlights: Surpassing ... (GuruFocus.com)
May-02-24 09:24PM	Q1 2024 Blueprint Medicines Corp Earnings Call (Thomson Reuters StreetEvents) +12.80%
11:56AM	BPMC Stock Earnings: Blueprint Medicines Beats EPS, Beats Revenue for Q1 2024 (InvestorPlace)
10:56AM	Wedbush Raises Blueprint Medicines' Price Target to $120 From $110 After Stronger-Than-Expected Q1 Results, Keeps Outperform Rating (MT Newswires)
10:16AM	Blueprint Medicines Shares Rise After Q1 Swings to Net Income, Revenue Rises (MT Newswires)
08:36AM	Blueprint Medicines Corp Reports Q1 2024 Earnings, Surpasses Revenue Estimates and Raises ... (GuruFocus.com)
08:10AM	Blueprint Medicines (BPMC) Reports Q1 Loss, Tops Revenue Estimates (Zacks)
07:11AM	Blueprint Medicines: Q1 Earnings Snapshot (Associated Press Finance)
07:00AM	Blueprint Medicines Reports Strong First Quarter 2024 Results and Raises AYVAKIT/AYVAKYT (avapritinib) Full Year Revenue Guidance (PR Newswire)
Apr-25-24 10:01AM	Blueprint Medicines (BPMC) Expected to Beat Earnings Estimates: What to Know Ahead of Q1 Release (Zacks)
Apr-18-24 08:00AM	Blueprint Medicines to Report First Quarter 2024 Financial Results on Thursday, May 2, 2024 (PR Newswire)
Apr-11-24 08:00AM	Blueprint Medicines to Host Webcast and Conference Call Highlighting Emerging Opportunities for Mast Cell-Targeted Therapeutics (PR Newswire)

Blueprint Medicines Corp. is a precision therapy company, which engages in the provision of medicines for people with cancer and blood disorders. The company was founded by Chris Varma, Nicholas B. Lydon, Brian Druker, and Alexis Borisy on October 14, 2008 and is headquartered in Cambridge, MA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Carter Percy H.	CHIEF SCIENTIFIC OFFICER	Jun 03 '25	Sale	127.88	2,659	340,033	54,206	Jun 05 04:22 PM
Albers Jeffrey W.	Director	May 27 '25	Option Exercise	36.05	5,000	180,250	151,630	May 29 04:20 PM
Albers Jeffrey W.	Director	May 27 '25	Sale	101.14	5,000	505,692	146,630	May 29 04:20 PM
Albers Jeffrey W.	Director	May 27 '25	Proposed Sale	101.14	5,000	505,686		May 27 09:06 PM
Rossi Christina	CHIEF OPERATING OFFICER	May 19 '25	Sale	100.51	2,274	228,557	64,718	May 21 04:33 PM
Rossi Christina	CHIEF OPERATING OFFICER	May 05 '25	Sale	101.75	2,274	231,386	66,992	May 07 04:32 PM
Hurley Ariel	PRINCIPAL ACCOUNTING OFFICER	May 05 '25	Option Exercise	54.13	2,752	148,966	19,696	May 07 04:30 PM
Hurley Ariel	PRINCIPAL ACCOUNTING OFFICER	May 05 '25	Sale	103.13	2,752	283,819	16,944	May 07 04:30 PM
ARIEL HURLEY	Officer	May 05 '25	Proposed Sale	104.64	2,942	307,851		May 05 04:57 PM
Haviland Kate	CHIEF EXECUTIVE OFFICER	Apr 01 '25	Sale	86.65	2,498	216,461	165,929	Apr 03 04:30 PM
KATHRYN D HAVILAND	Officer	Apr 01 '25	Proposed Sale	88.51	2,498	221,098		Apr 01 04:20 PM
Rossi Christina	CHIEF OPERATING OFFICER	Mar 24 '25	Sale	95.02	2,274	216,075	69,266	Mar 26 04:27 PM
Christina Rossi	Officer	Mar 24 '25	Proposed Sale	89.20	9,096	811,363		Mar 24 05:04 PM
Albers Jeffrey W.	Director	Mar 05 '25	Sale	88.80	5,766	512,021	146,630	Mar 17 04:26 PM
Albers Jeffrey W.	Director	Mar 12 '25	Option Exercise	36.05	7,500	270,375	159,896	Mar 14 04:36 PM
Albers Jeffrey W.	Director	Mar 12 '25	Sale	87.80	7,500	658,500	152,396	Mar 14 04:36 PM
Hewes L. Becker	CHIEF MEDICAL OFFICER	Mar 06 '25	Sale	87.69	5,232	458,804	30,419	Mar 07 04:15 PM
Hewes L. Becker	CHIEF MEDICAL OFFICER	Mar 05 '25	Sale	88.80	4,863	431,834	35,651	Mar 07 04:15 PM
Rossi Christina	CHIEF OPERATING OFFICER	Mar 05 '25	Sale	88.80	6,495	576,756	71,540	Mar 07 04:14 PM
Namouni Fouad	PRESIDENT, R & D	Mar 05 '25	Sale	88.80	6,489	576,223	75,781	Mar 07 04:13 PM
McCain Tracey L	EVP AND CHIEF LEGAL OFFICER	Mar 05 '25	Sale	88.80	5,262	467,266	66,583	Mar 07 04:12 PM
Lee Philina	CHIEF COMMERCIAL OFFICER	Mar 05 '25	Sale	88.80	3,733	331,490	41,996	Mar 07 04:11 PM
Landsittel Michael	CHIEF FINANCIAL OFFICER	Mar 05 '25	Sale	88.80	5,284	469,219	72,924	Mar 07 04:10 PM
Hurley Ariel	PRINCIPAL ACCOUNTING OFFICER	Mar 05 '25	Sale	88.80	1,326	117,749	16,944	Mar 07 04:09 PM
Haviland Kate	CHIEF EXECUTIVE OFFICER	Mar 05 '25	Sale	88.80	16,151	1,434,209	168,427	Mar 07 04:08 PM
Durso-Bumpus Debra	CHIEF PEOPLE OFFICER	Mar 05 '25	Sale	88.80	5,157	457,942	49,606	Mar 07 04:07 PM
Carter Percy H.	CHIEF SCIENTIFIC OFFICER	Mar 05 '25	Sale	88.80	3,530	313,464	56,865	Mar 07 04:06 PM
LEMUEL BECKER HEWES	Officer	Mar 06 '25	Proposed Sale	87.69	5,232	458,804		Mar 06 04:19 PM
Hurley Ariel	PRINCIPAL ACCOUNTING OFFICER	Mar 03 '25	Sale	92.62	3,203	296,666	18,270	Mar 04 05:20 PM
ARIEL HURLEY	Officer	Mar 03 '25	Proposed Sale	96.57	2,250	217,282		Mar 03 04:15 PM
Rossi Christina	CHIEF OPERATING OFFICER	Feb 20 '25	Sale	95.14	2,274	216,348	64,835	Feb 24 04:15 PM
Haviland Kate	CHIEF EXECUTIVE OFFICER	Jan 21 '25	Sale	110.24	1,446	159,407	149,378	Jan 23 07:56 PM
Rossi Christina	CHIEF OPERATING OFFICER	Jan 21 '25	Sale	110.14	2,274	250,455	67,109	Jan 23 07:54 PM
Albers Jeffrey W.	Director	Jan 21 '25	Option Exercise	36.05	10,000	360,500	167,557	Jan 23 07:53 PM
Albers Jeffrey W.	Director	Jan 21 '25	Sale	109.53	15,161	1,660,511	152,396	Jan 23 07:53 PM
CHRISTOPHER MURRAY	Officer	Jan 23 '25	Proposed Sale	111.08	2,500	277,700		Jan 23 04:23 PM
Albers Jeffrey W.	Director	Jan 21 '25	Proposed Sale	109.79	5,161	566,627		Jan 21 09:25 PM
CHRISTOPHER MURRAY	Officer	Jan 17 '25	Proposed Sale	103.95	2,500	259,875		Jan 17 04:24 PM
Albers Jeffrey W.	Director	Jan 13 '25	Option Exercise	36.05	5,000	180,250	162,557	Jan 15 06:04 PM
Albers Jeffrey W.	Director	Jan 13 '25	Sale	102.28	5,000	511,400	157,557	Jan 15 06:04 PM
Hurley Ariel	PRINCIPAL ACCOUNTING OFFICER	Jan 13 '25	Option Exercise	36.05	2,250	81,112	17,217	Jan 15 06:03 PM
Hurley Ariel	PRINCIPAL ACCOUNTING OFFICER	Jan 13 '25	Sale	100.00	2,250	225,000	14,967	Jan 15 06:03 PM
Albers Jeffrey W.	Director	Jan 13 '25	Proposed Sale	102.28	5,000	511,398		Jan 14 04:50 PM
Albers Jeffrey W.	Director	Dec 19 '24	Option Exercise	36.05	15,000	540,750	172,557	Dec 20 04:15 PM
Albers Jeffrey W.	Director	Dec 19 '24	Sale	89.77	15,000	1,346,615	157,557	Dec 20 04:15 PM
Rossi Christina	CHIEF OPERATING OFFICER	Dec 18 '24	Sale	95.91	2,274	218,098	69,383	Dec 20 04:15 PM
Albers Jeffrey W.	Director	Dec 19 '24	Proposed Sale	89.78	15,000	1,346,633		Dec 19 05:17 PM
Hurley Ariel	PRINCIPAL ACCOUNTING OFFICER	Dec 12 '24	Option Exercise	15.01	1,600	24,016	16,786	Dec 16 07:51 PM
Hurley Ariel	PRINCIPAL ACCOUNTING OFFICER	Dec 12 '24	Sale	93.26	1,819	169,636	14,967	Dec 16 07:51 PM
ARIEL HURLEY	Officer	Dec 12 '24	Proposed Sale	94.47	5,022	474,428		Dec 12 04:52 PM
Haviland Kate	CHIEF EXECUTIVE OFFICER	Nov 29 '24	Sale	96.60	2,353	227,304	150,824	Dec 03 05:33 PM
Rossi Christina	CHIEF OPERATING OFFICER	Nov 27 '24	Sale	95.10	2,274	216,257	71,657	Dec 02 06:52 PM
KATHRYN D HAVILAND	Officer	Nov 29 '24	Proposed Sale	95.10	3,799	361,285		Nov 29 01:40 PM
Christina Rossi and Gregory Pa	Affiliate	Nov 27 '24	Proposed Sale	94.63	9,096	860,754		Nov 27 06:51 PM
COATS LONNEL	Director	Nov 20 '24	Option Exercise	70.75	8,812	623,452	22,066	Nov 22 04:47 PM
COATS LONNEL	Director	Nov 20 '24	Sale	93.77	10,000	937,655	12,066	Nov 22 04:47 PM
COATS LONNEL	Director	Nov 21 '24	Sale	94.87	9,824	932,003	2,242	Nov 22 04:47 PM
LONNEL COATS	Director	Nov 21 '24	Proposed Sale	94.81	9,824	931,413		Nov 21 04:23 PM
LONNEL COATS	Director	Nov 20 '24	Proposed Sale	94.60	10,000	946,000		Nov 20 04:30 PM
Albers Jeffrey W.	Director	Nov 07 '24	Option Exercise	36.05	5,000	180,250	162,557	Nov 12 04:15 PM
Albers Jeffrey W.	Director	Nov 07 '24	Sale	102.00	5,000	510,000	157,557	Nov 12 04:15 PM
Albers Jeffrey W.	Director	Nov 07 '24	Proposed Sale	102.00	5,000	510,000		Nov 07 05:24 PM
Namouni Fouad	PRESIDENT, R & D	Oct 03 '24	Sale	89.32	3,633	324,500	69,070	Oct 04 05:09 PM
Albers Jeffrey W.	Director	Sep 09 '24	Option Exercise	36.05	10,000	360,500	177,259	Sep 11 04:06 PM
Albers Jeffrey W.	Director	Sep 09 '24	Sale	85.57	19,702	1,685,891	157,557	Sep 11 04:06 PM
Albers Jeffrey W.	Director	Sep 09 '24	Proposed Sale	85.57	19,702	1,685,911		Sep 09 09:22 PM
Landsittel Michael	CHIEF FINANCIAL OFFICER	Aug 15 '24	Sale	95.23	4,409	419,869	67,208	Aug 19 04:00 PM
MICHAEL LANDSITTEL	Officer	Aug 15 '24	Proposed Sale	95.23	4,409	419,891		Aug 15 04:27 PM
Lee Philina	CHIEF COMMERCIAL OFFICER	Aug 05 '24	Option Exercise	67.50	41,913	2,828,921	76,642	Aug 07 05:06 PM
Lee Philina	CHIEF COMMERCIAL OFFICER	Aug 05 '24	Sale	93.19	41,913	3,905,872	34,729	Aug 07 05:06 PM
Lee Philina	Officer	Aug 05 '24	Proposed Sale	93.00	46,436	4,318,548		Aug 05 04:50 PM
Durso-Bumpus Debra	CHIEF PEOPLE OFFICER	Jul 03 '24	Option Exercise	54.13	8,817	477,264	52,580	Jul 08 04:05 PM
Durso-Bumpus Debra	CHIEF PEOPLE OFFICER	Jul 05 '24	Option Exercise	54.13	3,850	208,400	47,613	Jul 08 04:05 PM
Durso-Bumpus Debra	CHIEF PEOPLE OFFICER	Jul 03 '24	Sale	111.29	8,817	981,244	43,763	Jul 08 04:05 PM
Durso-Bumpus Debra	CHIEF PEOPLE OFFICER	Jul 05 '24	Sale	111.20	3,850	428,120	43,763	Jul 08 04:05 PM
Durso-Bumpus Debra	CHIEF PEOPLE OFFICER	Jun 28 '24	Option Exercise	54.13	333	18,025	44,096	Jul 02 04:05 PM
Durso-Bumpus Debra	CHIEF PEOPLE OFFICER	Jun 28 '24	Sale	111.15	333	37,013	43,763	Jul 02 04:05 PM
Durso-Bumpus Debra	CHIEF PEOPLE OFFICER	Jun 21 '24	Option Exercise	34.48	60,482	2,085,501	117,797	Jun 25 04:00 PM
Durso-Bumpus Debra	CHIEF PEOPLE OFFICER	Jun 21 '24	Sale	104.19	74,034	7,713,537	43,763	Jun 25 04:00 PM

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SYRE

Spyre Therapeutics Inc

Jun 06 • 04:00PM ET

16.97

Dollar change +0.35
Percentage change 2.11	%

Healthcare • Biotechnology • USA • NASD

SYRE Spyre Therapeutics Inc daily Stock Chart

Peers: AMGN GILD REGN VRTX BIIB MRNA BMY PFE LLY NVS

| Held by: VTI IWM XBI VXF IWN IBB SCHA VTWO VHT LABU

Index	RUT	P/E	-	EPS (ttm)	-3.03	Insider Own	14.56%	Shs Outstand	60.28M	Perf Week	11.06%
Market Cap	1.02B	Forward P/E	-	EPS next Y	-3.30	Insider Trans	0.00%	Shs Float	51.56M	Perf Month	33.52%
Income	-160.22M	PEG	-	EPS next Q	-0.75	Inst Own	99.38%	Short Float	23.85%	Perf Quarter	-12.93%
Sales	0.00M	P/S	-	EPS this Y	2.80%	Inst Trans	2.78%	Short Ratio	19.06	Perf Half Y	-37.77%
Book/sh	5.42	P/B	3.13	EPS next Y	-6.73%	ROA	-30.31%	Short Interest	12.30M	Perf Year	-50.23%
Cash/sh	9.36	P/C	1.81	EPS next 5Y	-2.32%	ROE	-50.47%	52W Range	10.91 - 40.26	Perf YTD	-27.10%
Dividend Est.	-	P/FCF	-	EPS past 5Y	44.65%	ROI	-33.20%	52W High	-57.85%	Beta	2.72
Dividend TTM	-	Quick Ratio	8.06	Sales past 5Y	-	Gross Margin	-	52W Low	55.55%	ATR (14)	0.93
Dividend Ex-Date	-	Current Ratio	8.06	EPS Y/Y TTM	94.51%	Oper. Margin	-	RSI (14)	65.42	Volatility	3.41% 3.33%
Employees	65	Debt/Eq	0.00	Sales Y/Y TTM	-100.00%	Profit Margin	-	Recom	1.27	Target Price	54.67
Option/Short	Yes / Yes	LT Debt/Eq	0.00	EPS Q/Q	17.20%	Payout	-	Rel Volume	0.48	Prev Close	16.62
Sales Surprise	-	EPS Surprise	28.66%	Sales Q/Q	-	Earnings	May 08 AMC	Avg Volume	645.32K	Price	16.97
SMA20	10.76%	SMA50	16.88%	SMA200	-26.49%	Trades		Volume	309,214	Change	2.11%

Date	Action	Analyst	Rating Change	Price Target Change
Apr-08-25	Initiated	Leerink Partners	Outperform	$45
Mar-18-25	Initiated	Wolfe Research	Outperform	$27
Sep-04-24	Initiated	Wedbush	Outperform	$45
Jul-16-24	Initiated	Evercore ISI	Outperform
May-02-24	Initiated	Robert W. Baird	Outperform	$50
Mar-01-24	Upgrade	Wells Fargo	Equal Weight → Overweight	$12 → $35
Dec-20-23	Initiated	BTIG Research	Buy	$32
Dec-11-23	Initiated	Jefferies	Buy	$31
Dec-11-23	Initiated	Guggenheim	Buy	$44
May-04-20	Initiated	Piper Sandler	Overweight	$12
Mar-21-19	Initiated	JP Morgan	Overweight	$14
Sep-04-18	Downgrade	Wells Fargo	Outperform → Market Perform
Apr-24-18	Initiated	Evercore ISI	Outperform	$37
Mar-14-18	Reiterated	Needham	Buy	$8 → $12

Show Previous Ratings

Today 04:05PM	Spyre Therapeutics Announces Grants of Inducement Awards (PR Newswire)
May-30-25 09:55AM	Wall Street Analysts Predict a 244.05% Upside in Spyre Therapeutics (SYRE): Here's What You Should Know (Zacks)
May-28-25 08:30AM	Spyre Therapeutics to Participate in Upcoming June Investor Conferences (PR Newswire)
May-13-25 09:55AM	How Much Upside is Left in Spyre Therapeutics (SYRE)? Wall Street Analysts Think 258.34% (Zacks)
May-08-25 04:05PM	Spyre Therapeutics Reports First Quarter 2025 Financial Results and Provides Corporate Update (PR Newswire) +9.64%
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May-05-25 08:00AM	Spyre Therapeutics Announces Poster Presentations at Digestive Disease Week (DDW) 2025 Including Up to Eight months of Follow-up from an Ongoing Phase 1 Trial of SPY001 (PR Newswire) -6.75%
May-02-25 04:05PM	Spyre Therapeutics Announces Grants of Inducement Awards (PR Newswire)
Apr-04-25 04:05PM	Spyre Therapeutics Announces Grants of Inducement Awards (PR Newswire) -8.58%
Mar-27-25 04:05PM	Spyre Therapeutics Announces First Participant Dosed in Phase 1 Trial of SPY003, its Novel Half-life Extended IL-23 Antibody (PR Newswire)
Mar-07-25 04:40PM	Spyre Therapeutics Announces Grants of Inducement Awards (PR Newswire)
Feb-27-25 04:05PM	Spyre Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Corporate Update (PR Newswire) +7.24%
Feb-25-25 08:00AM	Spyre Therapeutics to Participate in Upcoming March Investor Conferences (PR Newswire)
Feb-19-25 08:00AM	Spyre Therapeutics Announces Poster Presentation at the 20th Congress of the European Crohn's and Colitis Organisation (PR Newswire)
Feb-07-25 05:13PM	Spyre Therapeutics Announces Grants of Inducement Awards (PR Newswire) -5.07%
Jan-13-25 08:00AM	Spyre Therapeutics Highlights 2025 Priorities and Robust Pipeline of Upcoming Clinical Readouts (PR Newswire)
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Jan-03-25 05:20PM	Spyre Therapeutics Announces Grants of Inducement Awards (PR Newswire)
Dec-18-24 08:00AM	Spyre Therapeutics Added to the Nasdaq Biotechnology Index (PR Newswire) -8.31%
Dec-02-24 05:03PM	Spyre Therapeutics Announces Grants of Inducement Awards (PR Newswire)
08:00AM	Spyre Therapeutics Announces First Participants Dosed in Phase 1 Trials of Novel Half-life Extended Anti-TL1A Antibodies (PR Newswire)
Nov-25-24 05:11PM	Spyre Therapeutics to Participate in the 7th Annual Evercore ISI HealthCONx Conference (PR Newswire)
Nov-18-24 09:18PM	Spyre Therapeutics Announces Pricing of $200 Million Public Offering of Common Stock (PR Newswire) -6.17%
04:14PM	Spyre Therapeutics Announces Proposed Public Offering of its Common Stock and Pre-Funded Warrants (PR Newswire)
Nov-12-24 07:30AM	Spyre Therapeutics Announces Positive Interim Results from Phase 1 Healthy Volunteer Trial for SPY001, Its Novel Half-Life Extended anti-47 Antibody for the Treatment of Inflammatory Bowel Disease, with a Half-Life of >90 Days Supporting the Potential for Both Q3M & Q6M Maintenance Dosing (PR Newswire) -8.97%
Nov-11-24 04:05PM	Spyre Therapeutics to Host Conference Call and Webcast to Report Interim Results from Phase 1 Healthy Volunteer Trial for SPY001, its Novel Half-Life Extended Anti-47 Antibody for the Treatment for Inflammatory Bowel Disease on November 12, 2024 (PR Newswire)
Nov-07-24 04:05PM	Spyre Therapeutics Reports Third Quarter 2024 Financial Results and Provides Corporate Update (PR Newswire) +5.00%
Nov-01-24 04:44PM	Spyre Therapeutics Announces Grants of Inducement Awards (PR Newswire)
Oct-30-24 04:05PM	Spyre Therapeutics to Participate in Upcoming November Investor Conferences (PR Newswire)
Oct-14-24 08:00AM	Spyre Therapeutics Announces Expected Acceleration of SPY003 (IL-23p19) Clinical Timelines and Presentations at UEGW supporting Spyre's Portfolio of Potentially Best-in-Class Antibodies and Combinations (PR Newswire) +6.83%
Oct-04-24 05:00PM	Spyre Therapeutics Announces Grants of Inducement Awards (PR Newswire) -5.66%
Oct-01-24 08:00AM	Spyre Therapeutics Appoints Dr. Sheldon Sloan as Chief Medical Officer (PR Newswire) -6.63%
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Sep-10-24 04:47PM	Spyre Therapeutics to Participate in Upcoming Investor Conference (PR Newswire)
Aug-07-24 11:53PM	SYRE Stock Earnings: Spyre Therapeutics Beats EPS for Q2 2024 (InvestorPlace) -5.72%
04:05PM	Spyre Therapeutics Reports Second Quarter 2024 Financial Results and Provides Corporate Update (PR Newswire)
Jul-18-24 08:00AM	NewAmsterdam Pharma Announces Appointments of Mark C. McKenna and Wouter Joustra to its Board of Directors (GlobeNewswire) -5.22%
Jun-18-24 07:30AM	Spyre Therapeutics Announces First Participants Dosed in Phase 1 Trial of SPY001, its Novel Half-life Extended anti-47 Antibody, for the Treatment of Inflammatory Bowel Disease (PR Newswire)
Jun-03-24 05:23PM	Spyre Therapeutics Announces Grants of Inducement Awards (PR Newswire) +5.26% -7.31%
May-29-24 08:30AM	Spyre Therapeutics to Participate in the Jefferies Global Healthcare Conference (PR Newswire)
May-15-24 07:30AM	Spyre Therapeutics Appoints Accomplished Biopharma Leader Dr. Sandra Milligan to its Board of Directors (PR Newswire)
May-09-24 10:54PM	SYRE Stock Earnings: Spyre Therapeutics Misses EPS for Q1 2024 (InvestorPlace) +6.57%
04:02PM	Spyre Therapeutics Reports First Quarter 2024 Financial Results and Provides Corporate Update (PR Newswire)
May-03-24 05:00PM	Spyre Therapeutics Announces Grants of Inducement Awards (PR Newswire)
Apr-01-24 05:00PM	Spyre Therapeutics Announces Grants of Inducement Awards (PR Newswire) -7.27%
Mar-18-24 08:00AM	Spyre Therapeutics Announces $180 Million Private Placement (PR Newswire) -11.68%
Mar-04-24 08:50AM	Here's What Could Help Spyre Therapeutics (SYRE) Maintain Its Recent Price Strength (Zacks) +16.96%
Mar-01-24 05:25PM	Spyre Therapeutics Announces Grants of Inducement Awards (PR Newswire) +8.97%
Feb-29-24 04:05PM	Spyre Therapeutics Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Corporate Update (PR Newswire) +5.13%
Feb-26-24 07:30AM	Spyre Therapeutics to Participate in the 44th Annual TD Cowen Health Care Conference (PR Newswire)
Feb-08-24 07:30AM	Spyre Therapeutics Announces Three Abstracts Accepted for Presentation at the 19th Annual Congress of the European Crohn's and Colitis Organisation (PR Newswire)
Feb-06-24 09:55AM	Here's Why Spyre Therapeutics (SYRE) Could be Great Choice for a Bottom Fisher (Zacks)
Feb-05-24 07:30AM	Spyre Therapeutics Appoints Accomplished Biopharma and IBD Leader Mark C. McKenna, Former Chairman, President, and CEO of Prometheus Biosciences, to its Board of Directors (PR Newswire)
Feb-02-24 05:30PM	Spyre Therapeutics Announces Grants of Inducement Awards (PR Newswire)
Dec-22-23 05:00PM	Spyre Therapeutics Announces Grants of Inducement Awards (PR Newswire) +5.52% +6.22%
Dec-08-23 07:19AM	Spyre Therapeutics raises $180 million to advance anti-inflammatory drugs (BioPharma Dive)
Dec-07-23 06:20PM	Spyre Therapeutics Announces $180 Million Private Placement (PR Newswire)
Nov-28-23 08:00AM	Spyre Therapeutics to Present at Upcoming Investor Conference (PR Newswire) +20.73%
Nov-27-23 08:30AM	Aeglea BioTherapeutics Announces Name Change to Spyre Therapeutics, Appoints CEO and Additional Directors, and Expands Leadership Team to Develop Next-Generation Therapeutic Combinations for the Treatment of IBD (PR Newswire) +8.79%
Nov-22-23 05:00PM	Aeglea BioTherapeutics Announces Grants of Inducement Awards (PR Newswire) +6.26%
Nov-09-23 06:26PM	Aeglea: Q3 Earnings Snapshot (Associated Press Finance)
04:05PM	Aeglea BioTherapeutics Reports Third Quarter 2023 Financial Results and Provides Corporate Update (PR Newswire)
Nov-03-23 05:00PM	Aeglea BioTherapeutics Announces Grants of Inducement Awards (PR Newswire) -5.39%
Oct-30-23 08:00PM	Aeglea BioTherapeutics to Participate in Upcoming November Investor Conferences (PR Newswire) +9.57%
Oct-02-23 06:02PM	Aeglea BioTherapeutics Announces Grants of Inducement Awards (PR Newswire)
Sep-14-23 05:03PM	Aeglea BioTherapeutics to Participate in Upcoming September Conference (PR Newswire) -6.63%
Sep-07-23 08:40AM	Aeglea BioTherapeutics Announces Reverse Stock Split (PR Newswire)
Sep-05-23 07:00AM	Aeglea BioTherapeutics Expands Executive Leadership Team with Appointment of Industry Veterans Scott Burrows and Heidy Abreu King-Jones (PR Newswire)
Aug-11-23 07:07AM	Aeglea: Q2 Earnings Snapshot (Associated Press Finance)
07:00AM	Aeglea BioTherapeutics Reports Second Quarter 2023 Financial Results (PR Newswire)
Jul-27-23 07:00AM	Aeglea BioTherapeutics Announces Sale of Pegzilarginase to Immedica Pharma (PR Newswire)
Jun-23-23 04:30PM	Aeglea BioTherapeutics Announces Grant of Inducement Awards (PR Newswire) -12.30% -5.30%
10:31AM	Aeglea (AGLE) Soars 329% on Acquiring Spyre Therapeutics (Zacks)
Jun-22-23 10:59AM	Aeglea BioTherapeutics Stock Surges Over 400% Today - What's Going On (Benzinga) +328.67%
08:17AM	Aeglea BioTherapeutics Announces Acquisition of Spyre Therapeutics (PR Newswire)
May-13-23 08:03AM	Aeglea BioTherapeutics First Quarter 2023 Earnings: Revenues Beat Expectations, EPS Lags (Simply Wall St.)
May-11-23 08:15AM	Aeglea Biotherapeutics (AGLE) Reports Q1 Loss, Tops Revenue Estimates (Zacks)
07:10AM	Aeglea: Q1 Earnings Snapshot (AP Finance)
07:01AM	Aeglea BioTherapeutics Reports First Quarter 2023 Financial Results (PR Newswire)
Apr-13-23 09:44AM	Aeglea (AGLE) Plunges 26% After Rare Disorder Drug Study Fails (Zacks) -7.37%
Apr-12-23 07:00AM	Aeglea BioTherapeutics Announces Interim Results from Ongoing Phase 1/2 Clinical Trial of Pegtarviliase for the Treatment of Classical Homocystinuria and Begins Process to Explore Strategic Alternatives (PR Newswire) -26.21%
Mar-17-23 05:30PM	Aeglea BioTherapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (PR Newswire) -8.35%
Mar-02-23 10:15AM	Aeglea Biotherapeutics (AGLE) Reports Q4 Loss, Lags Revenue Estimates (Zacks)
07:01AM	Aeglea BioTherapeutics Reports Fourth Quarter and Full Year 2022 Financial Results and Provides Program Updates (PR Newswire)
Feb-12-23 07:40AM	Aeglea BioTherapeutics, Inc. (NASDAQ:AGLE) insiders placed bullish bets worth US$695k in the last 12 months (Simply Wall St.)
Jan-06-23 07:01AM	Aeglea BioTherapeutics Announces Update to Corporate Structure to Increase Operational Efficiency (PR Newswire)
Jan-02-23 07:29AM	Here's Why Aeglea BioTherapeutics (NASDAQ:AGLE) Must Use Its Cash Wisely (Simply Wall St.)
Dec-14-22 12:00PM	Aeglea (AGLE) Moves to Buy: Rationale Behind the Upgrade (Zacks)
Dec-02-22 04:05PM	Aeglea BioTherapeutics Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) (PR Newswire) +18.17% -5.90%
Nov-30-22 10:38AM	Aeglea Nosedives After Clinical Update On Investigational Candidate For Rare Metabolism Disease (Benzinga) -65.98%
07:01AM	Aeglea BioTherapeutics Appoints Jeffrey M. Goldberg as Chief Executive Officer (PR Newswire)
Nov-15-22 04:25PM	Aeglea BioTherapeutics Appoints Linda Neuman, M.D., M.B.A, to Chief Medical Officer (PR Newswire) -5.88%
Nov-03-22 08:35AM	Aeglea Biotherapeutics (AGLE) Reports Q3 Loss, Misses Revenue Estimates (Zacks) -6.56%
07:01AM	Aeglea BioTherapeutics Reports Third Quarter 2022 Financial Results and Provides Program Updates (PR Newswire)
Oct-21-22 12:27PM	Gilead (GILD) Inks Deal for Gene Platform in Blood Cancers (Zacks) +6.02%
12:06PM	AbbVie (ABBV) to Boost Immunology Pipeline With New Acquisition (Zacks)
Oct-19-22 04:05PM	Aeglea BioTherapeutics Hosting Key Opinion Leader Webinar on Classical Homocystinuria and Pegtarviliase's Potential Role in Treatment (PR Newswire)
Oct-17-22 11:57AM	NeuBase (NBSE) Up on Restructuring Plan, Set to Lower Workforce (Zacks)
Oct-04-22 11:05AM	FDA Puts Partial Hold On Aeglea's Rare Disorder Trial In Pediatric Patients (Benzinga)
07:01AM	Aeglea BioTherapeutics Provides Clinical Progress and Regulatory Update for Homocystinuria Program (PR Newswire)
Aug-29-22 04:05PM	Aeglea BioTherapeutics Announces Presentations at the Society for the Study of Inborn Errors of Metabolism (SSIEM) Annual Symposium 2022 (PR Newswire) +16.74% -13.51%
Aug-27-22 09:18AM	Trade Alert: Marcio De'Souza At Aeglea BioTherapeutics, Inc. (NASDAQ:AGLE), Has Just Spent US$50k Buying A Small Number of Shares (Simply Wall St.)
Aug-25-22 11:52AM	Aeglea (AGLE) Down on Corporate Restructuring, CEO Steps Down (Zacks)

Spyre Therapeutics, Inc. is a clinical-stage biotechnology company, which engages in the development of next-generation human enzyme therapeutics as disruptive solutions for rare and other high-burden diseases. Its product, Pegzilarginase, is in a Phase 3 pivotal trial for the treatment of Arginase 1 Deficiency. The company was founded by George Georgiou and David G. Lowe on December 16, 2013 and is headquartered in Waltham, MA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Albers Jeffrey W.	Director	Nov 06 '24	Sale	36.76	6,700	246,313	27,360	Nov 08 04:53 PM
Albers Jeffrey W.	Director	Oct 25 '24	Sale	36.43	300	10,929	34,060	Oct 28 04:41 PM
SESSIONS, LLC	Director	Oct 25 '24	Proposed Sale	33.70	7,000	235,900		Oct 25 04:28 PM
Burrows Scott L	Chief Financial Officer	Sep 03 '24	Sale	28.17	18,531	522,074	116,422	Sep 05 04:04 PM

KYMR

Kymera Therapeutics Inc

BPMC

Blueprint Medicines Corp

SYRE

Spyre Therapeutics Inc

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