Point.360 operates as an integrated media management services company in the United States. It offers film, video and audio post-production, archival, duplication, and data distribution services. The company also provides services to edit, master, reformat, convert, archive, and distribute its clients' audio, video, and film content, including television programming, feature films, and movie trailers. Its value-added services comprise digital and video editing, digital color correction, picture restoration, audio post-production, audio restoration and layback, closed captioning and subtitling, foreign language mastering, standards conversion, broadcast encoding, global distribution and syndication, and archival services. In addition, Point.360 is involved in the rental and sale of DVDs and video games to consumers through its Movie>Q retail stores. Its customers include independent motion picture and television studios, cable television program suppliers, and television program syndicators, as well as national television networks, local television stations, corporate or instructional video providers, and educational institutions. The company is based in Los Angeles, California.
Progenics Pharmaceuticals, Inc. develops medicines for oncology in the United States and internationally. The company's primary clinical-stage product candidates include prostate specific membrane antigen (PSMA) antibody-drug conjugate, which has completed Phase II testing in chemotherapy-experienced patients and is ongoing second cohort in chemotherapy-nave patients for the treatment of prostate cancer; 1404, a radio-labeled small molecule that has completed Phase II testing, as well as acts as an imaging agent to diagnose and detect prostate cancer; and Azedra, a radiotherapeutic product candidate, which is in Phase IIb registrational trial under special protocol assessment for the treatment of pheochromocytoma and paraganglioma. It also offers Relistor-subcutaneous injection for the treatment of opioid induced constipation (OIC) in advanced-illness patients receiving palliative care when laxative therapy has not been sufficient; and for treatment of OIC inpatients with non-cancer pain. In addition, the company develops Relistor-oral that has completed Phase III testing for the treatment of OIC. Further, it develops MIP-1095, a PSMA-targeted small molecule radiopharmaceutical that is in clinical development stage for the treatment of prostate cancer. The company has license agreement with Salix Pharmaceuticals, Inc. for the development and commercialization of Relistor worldwide; and with Amgen Fremont, Inc. to use its XenoMouse technology for generating human antibodies to PSMA, as well as has collaboration agreement with Seattle Genetics, Inc. Progenics Pharmaceuticals, Inc. was founded in 1986 and is based in Tarrytown, New York.
OncoGenex Pharmaceuticals, Inc., a biopharmaceutical company, develops and commercializes therapies that address treatment resistance in cancer patients. The company's product candidates include Custirsen that is in Phase III clinical development for the treatment in men with metastatic castrate-resistant prostate cancer, as well as in patients with non-small cell lung cancer; and Apatorsen, which is in two Phase I and seven randomized Phase II trials for the treatment of bladder, lung, pancreatic, and prostate cancers. It also develops OGX-225 that is in pre-clinical development for the treatment of solid tumors. The company has a collaboration agreement with Teva Pharmaceutical Industries Ltd. to develop and commercialize Custirsen. OncoGenex Pharmaceuticals, Inc. is headquartered in Bothell, Washington.
BioSpecifics Technologies Corp., a biopharmaceutical company, engages in the development of an injectable collagenase clostridium histolyticum for multiple indications in the United States. The company offers injectable collagenase for the treatment of Dupuytren's contracture and Peyronie's disease under the XIAFLEX brand in Canada, Australia, Brazil, and Mexico, as well as under XIAPEX brand name in Europe. It also provides injectable collagenase to treat frozen shoulder, cellulite, human lipoma, canine lipoma, and uterine fibroids. The company is also involved in the development of other clinical indications for which collagenase injection has been tested include keloids, hypertrophic scars, scarred tendons, glaucoma, herniated intervertebral discs, and as an adjunct to vitrectomy. It has a development and license agreement with Auxilium Pharmaceuticals, Inc. BioSpecifics Technologies Corp. was founded in 1957 and is headquartered in Lynbrook, New York.
PRA Health Sciences, Inc., a contract research organization, provides various product development services for pharmaceutical and biotechnology companies worldwide. The company offers integrated services, such as data management, statistical analysis, clinical trial management, and regulatory and drug development consulting. Its services include a suite of product registration services, such as clinical trial management, project management, regulatory affairs, therapeutic expertise, clinical operations, data and programming, safety and risk management, biostatistics and medical writing, quality assurance, and late phase services. The company's services also comprise strategic solutions, including embedded, functional services provider, staff augmentation, and custom-built development solutions, as well as commercialization services; and early development services, including phase I through phase IIa clinical trials and bioanalytical laboratory services. It conducts clinical trials in the areas of pharmaceutical development, comprising oncology, central nervous system, inflammation, and infectious diseases. The company was formerly known as PRA Global Holdings, Inc. and changed its name to PRA Health Sciences, Inc. in July 2014. The company was founded in 1976 and is headquartered in Raleigh, North Carolina. PRA Health Sciences, Inc. is a subsidiary of KKR PRA Investors L.P.
ICON Public Limited Company, a contract research organization, provides outsourced development services to the pharmaceutical, biotechnology, and medical device industries in Ireland, rest of Europe, the United States, and internationally. It develops, manages, and analyzes programs that support various stages of the clinical development process from compound selection to Phase I-IV clinical studies. The company also offers clinical trials management, biometric activities, consulting, imaging, contract staffing, informatics, and laboratory services. Its clinical development services include investigator recruitment, study monitoring and data collection, case report form preparation, statistical analysis, patient safety monitoring, risk-based monitoring, clinical data management, interactive response technologies, electronic patient reported outcomes, medical reporting, patient registries, outcomes research, health economics, market access and commercialization services, strategic analysis and data operations, bioanalysis, immunoassay development, pharmacokinetic and pharmacodynamic analysis, and study protocol preparation. The company's clinical development services also comprise regulatory consulting, product development planning, strategic consulting, pricing and market access consulting, strategic resourcing, electronic endpoint adjudication, sample analyses, safety testing, microbiology, custom flow cytometry, electronic transmission of test results, biomarker development, adaptive trial design and execution, medical device trials, and healthcare communication services. ICON Public Limited Company was founded in 1990 and is headquartered in Dublin, Ireland.
MicroStrategy Incorporated designs, develops, markets, and sells enterprise-ready analytics, mobile, and security software platforms worldwide. It offers MicroStrategy Analytics Platform that delivers reports and dashboards, and enables users to conduct ad hoc analysis and share insights through mobile devices or the Web; and MicroStrategy Analytics Desktop to create data visualizations and dashboards. The company also provides MicroStrategy Mobile that enable organizations to build information-rich applications that deliver analytics combined with transactions, multimedia, and custom workflows to mobile devices; and MicroStrategy Usher, a mobile identity and security platform that primarily offers authentication, cybersecurity, access management, and resource authorization to businesses, universities, associations, governments, and other organizations. In addition, it offers MicroStrategy Secure Cloud that provides enterprise analytics and analytical databases, as well as extract, transform, load capabilities in an integrated environment. Further, the company provides technical support, consulting and advisory, and education services. It serves various industries, including retail, financial services and insurance, pharmaceutical and healthcare, manufacturing, consumer goods, government and public services, restaurants, and hospitality and leisure, as well as technology, media, and telecommunications. The company was founded in 1989 and is headquartered in Tysons Corner, Virginia.
Masco Corporation manufactures, distributes, and installs home improvement and building products worldwide. Its Cabinets and Related Products segment provides cabinetry for kitchen, bath, storage, home office, and home entertainment applications; and kitchen countertops, and integrated bathroom vanity and countertop solutions. The company's Plumbing Products segment offers faucets, showerheads, handheld showers, valves, bathing units, and toilets; acrylic tub and shower systems, bath and shower enclosure units, shower trays, and laundry tubs, as well as spas; and brass and copper plumbing system components, and other plumbing specialties. Its Decorative Architectural Products segment produces architectural coatings, including paints, primers, specialty paint products, stains, and waterproofing products; and cabinet, door, window, and other hardware products. The company's Other Specialty Products segment provides vinyl, fiberglass, and aluminum windows and patio doors; and manual and electric staple gun tackers, staples, and other fastening tools. Masco Corporation markets its products under the KRAFTMAID, MERILLAT, MOORES, QUALITY CABINETS, DELTA, PEERLESS, HANSGROHE, AXOR, BRIZO, BRASSTECH, BRISTAN, GINGER, HERITAGE, NEWPORT BRASS, PLUMB SHOP, HOT SPRING, CALDERA, FREEFLOW, MIROLIN, BRASSCRAFT, COBRA, MASTER PLUMBER, BEHRPRO, BEHR, KILZ, LIBERTY, BRAINERD, FRANKLIN BRASS, DECOR BATHWARE, MILGARD, GRIFFIN, PREMIER, and DURAFLEX brands. The company sells its products to home improvement and new home construction markets through mass merchandisers, hardware stores, home centers, homebuilders, distributors, and other outlets, as well as directly to the consumers. The company was founded in 1929 and is headquartered in Taylor, Michigan.
Reynolds American Inc., through its subsidiaries, manufactures and sells cigarettes and other tobacco products in the United States. It operates through RJR Tobacco, American Snuff, and Santa Fe segments. The RJR Tobacco segment offers cigarettes under the brand names of CAMEL, PALL MALL, WINSTON, KOOL, DORAL, SALEM, MISTY, and CAPRI; and CAMEL Snus, a smoke-free tobacco product, as well as manages various licensed brands, including DUNHILL and STATE EXPRESS 555. The American Snuff segment provides smokeless tobacco products, such as moist snuff under GRIZZLY and KODIAK brand names. The Santa Fe segment offers cigarettes and other tobacco products under the NATURAL AMERICAN SPIRIT brand name. The company also provides electronic cigarettes; manufactures digital vapor cigarettes under the VUSE brand name; and markets and distributes nicotine replacement therapy products under ZONNIC brand name in Sweden. It distributes its products primarily through direct wholesale deliveries from a local distribution center and public warehouses. Reynolds American Inc. was founded in 2004 and is headquartered in Winston-Salem, North Carolina.
Cadence Design Systems, Inc. develops, sells, leases, and licenses electronic design automation (EDA) software, emulation and prototyping hardware, verification intellectual property (VIP), and design intellectual property (design IP) for semiconductor and electronics systems industries worldwide. It offers functional verification products, including logic verification software that enables customers to coordinate verification activities across multiple teams and various specialists for verification planning and closure; and system design and verification products for hardware-software verification, as well as for system power exploration, analysis, and optimization. The company also provides digital integrated circuits (ICs) design products, such as logic design products for chip planning, design, verification, and test technologies and services; physical implementation products for use in place and route, signal integrity, optimization, and double patterning preparation; and signoff products to signoff the design as ready for manufacture by a silicon foundry, as well as design for manufacturing products for use in the product development process. In addition, it offers custom IC design and verification products to create schematic and physical representations of circuits down to the transistor level for analog, mixed-signal, custom digital, memory, and RF designs; and system interconnect design products to develop printed circuit boards and IC packages. Further, the company provides design IP products consisting of pre-verified and customizable functional blocks to integrate into customer's SoCs; and VIP and memory models for use in system-level verification to model correct behavior of full systems interacting with their environments. Additionally, it offers engineering, methodology, education, and hosted design solutions, as well as technical support and maintenance services. The company was founded in 1988 and is headquartered in San Jose, California.