CRL,PBE Stock Price and Quote

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Index	S&P 500	P/E	-	EPS (ttm)	-1.55	Insider Own	1.26%	Shs Outstand	49.22M	Perf Week	-14.72%
Market Cap	7.94B	Forward P/E	14.67	EPS next Y	11.00	Insider Trans	-0.19%	Shs Float	48.60M	Perf Month	-25.44%
Enterprise Value	10.41B	PEG	2.66	EPS next Q	2.35	Inst Own	106.59%	Short Float	5.53%	Perf Quarter	-5.92%
Income	-83.48M	P/S	1.97	EPS this Y	-0.76%	Inst Trans	3.83%	Short Ratio	3.29	Perf Half Y	3.56%
Sales	4.02B	P/B	2.33	EPS next Y	7.37%	ROA	-1.08%	Short Interest	2.69M	Perf YTD	-19.11%
Book/sh	69.20	P/C	38.24	EPS next 5Y	5.52%	ROE	-2.32%	52W High	228.88 -29.50%	Perf Year	5.34%
Cash/sh	4.22	P/FCF	14.61	EPS past 3/5Y	-70.29% -47.65%	ROIC	-1.38%	52W Low	91.86 75.65%	Perf 3Y	-36.35%
Dividend Est.	-	EV/EBITDA	11.47	Sales past 3/5Y	4.59% 9.09%	Gross Margin	29.73%	Volatility	6.47% 4.63%	Perf 5Y	-44.89%
Dividend TTM	-	EV/Sales	2.59	EPS Y/Y TTM	-118.96%	Oper. Margin	11.94%	ATR (14)	9.28	Perf 10Y	123.88%
Dividend Ex-Date	-	Quick Ratio	1.10	Sales Y/Y TTM	-0.92%	Profit Margin	-2.07%	RSI (14)	24.93	Recom	2.05
Dividend Gr. 3/5Y	- -	Current Ratio	1.37	EPS Q/Q	-17.30%	SMA20	-19.95%	Beta	1.67	Target Price	220.07
Payout	0.00%	Debt/Eq	0.77	Sales Q/Q	-0.49%	SMA50	-20.09%	Rel Volume	1.35	Prev Close	158.74
Employees	20100	LT Debt/Eq	0.77	Earnings	Feb 18 BMO	SMA200	-4.69%	Avg Volume	817.12K	Price	161.35
IPO	Jun 23, 2000	Option/Short	Yes / Yes	EPS/Sales Surpr.	3.95% 1.42%	Trades		Volume	1,102,264	Change	1.64%

Date	Action	Analyst	Rating Change	Price Target Change
Dec-15-25	Upgrade	BofA Securities	Neutral → Buy	$225
Nov-17-25	Upgrade	Argus	Hold → Buy
Nov-06-25	Upgrade	Robert W. Baird	Neutral → Outperform	$199
Oct-06-25	Upgrade	William Blair	Mkt Perform → Outperform
Oct-02-25	Upgrade	Barclays	Equal Weight → Overweight	$195
Sep-09-25	Upgrade	Jefferies	Hold → Buy	$195
Jul-09-25	Upgrade	Citigroup	Neutral → Buy	$200
May-23-25	Upgrade	Redburn Atlantic	Neutral → Buy	$182
May-14-25	Upgrade	TD Cowen	Hold → Buy	$179
May-08-25	Upgrade	Evercore ISI	In-line → Outperform	$170
Mar-21-25	Downgrade	Goldman	Buy → Neutral	$190 → $170
Mar-04-25	Upgrade	Citigroup	Sell → Neutral	$155 → $175
Mar-03-25	Upgrade	Redburn Atlantic	Sell → Neutral	$188
Jan-22-25	Downgrade	William Blair	Outperform → Mkt Perform
Jan-17-25	Downgrade	UBS	Buy → Neutral	$250 → $185
Nov-18-24	Downgrade	CLSA	Hold → Underperform	$164
Nov-07-24	Upgrade	CLSA	Underperform → Hold	$205
Oct-23-24	Initiated	CLSA	Underperform	$167
Oct-14-24	Initiated	Redburn Atlantic	Sell
Oct-07-24	Downgrade	Evercore ISI	Outperform → In-line	$225 → $190

Show Previous Ratings

Feb-13-26 09:39AM	Here's How Charles River Stock Is Placed Ahead of Q4 Earnings (Zacks)
07:01AM	Mariner selects State Streets Charles River wealth platform (Private Banker International)
Feb-12-26 02:27PM	Mariner Has Big Growth Plans. State Streets Charles River Is Supplying the Tech Platform. (Barrons.com)
Feb-11-26 08:21PM	Analyst Report: Charles River Laboratories International, Inc. (Morningstar Research) -8.42%
10:00AM	Analysts Estimate Charles River Laboratories (CRL) to Report a Decline in Earnings: What to Look Out for (Zacks)
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Feb-10-26 11:34PM	1 S&P 500 Stock with Competitive Advantages and 2 We Ignore (StockStory)
Feb-08-26 11:01PM	Charles River Laboratories (CRL): Buy, Sell, or Hold Post Q3 Earnings? (StockStory)
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Jan-21-26 04:30PM	Charles River Laboratories Schedules Fourth-Quarter 2025 Earnings and 2026 Guidance Release and Conference Call (Business Wire)
08:00AM	Charles River Enters Manufacturing Collaboration with Gazi University (Business Wire)
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Jan-19-26 05:59AM	What to Expect From Charles River Laboratories Next Quarterly Earnings Report (Barchart)
Jan-15-26 12:00PM	Here's Why Charles River Laboratories (CRL) is a Great Momentum Stock to Buy (Zacks)
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09:42AM	Phibro Animal Health Stock Climbs 90.9% in a Year: What's Driving It? (Zacks)
Jan-12-26 04:30PM	Charles River Laboratories Provides Business Updates (Business Wire)
08:57AM	RVTY & Eli Lilly Partner to Expand Access to AI Drug Discovery Models (Zacks)
Jan-09-26 07:45AM	Tempus AI Stock Surges 82.4% in a Year: What's Driving It? (Zacks)
Jan-08-26 08:00AM	Charles River Laboratories Announces Planned Retirement of James C. Foster and CEO Succession Plan (Business Wire)
Jan-06-26 12:00PM	What Makes Charles River (CRL) a New Buy Stock (Zacks)
09:15AM	Charles River Laboratories International, Inc. (CRL) Hit a 52 Week High, Can the Run Continue? (Zacks)
Dec-22-25 03:00PM	Why Charles River Laboratories (CRL) Stock Is Trading Up Today (StockStory)
Dec-18-25 08:36AM	Should You Continue to Hold CRL Stock in Your Portfolio for Now? (Zacks)
Dec-16-25 05:24AM	Is Charles River Laboratories Stock Underperforming the Dow? (Barchart)
Dec-15-25 04:36PM	Stocks Fall Ahead of US November Payroll Report (Barchart)
Dec-11-25 08:00AM	Charles River Extends Commitment to Advanced Therapy Developers with Second Incubator Program Cohort (Business Wire)
Dec-03-25 04:55PM	Charles River Laboratories (CRL) Shares Skyrocket, What You Need To Know (StockStory) +5.67%
Dec-01-25 03:42PM	HALPER SADEH LLC ENCOURAGES CHARLES RIVER LABORATORIES INTERNATIONAL, INC. SHAREHOLDERS TO CONTACT THE FIRM TO DISCUSS THEIR RIGHTS (PR Newswire)
Nov-24-25 07:56AM	What Makes Charles River Laboratories (CRL) an Investment Bet? (Insider Monkey)
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Nov-21-25 03:24AM	Charles River Laboratories Stock: Is Wall Street Bullish or Bearish? (Barchart)
Nov-20-25 11:54AM	MA life sciences company Charles River Laboratories to lay off dozens of workers in 2026 (Worcester Telegram & Gazette)
Nov-17-25 09:15AM	Charles River (CRL) International Revenue Performance Explored (Zacks)
08:00AM	Charles River Laboratories to Present at Jefferies Global Healthcare Conference (Business Wire)
Nov-16-25 10:37PM	Drug Development Inputs & Services Stocks Q3 Teardown: Charles River Laboratories (NYSE:CRL) Vs The Rest (StockStory)
Nov-12-25 12:32AM	5 Must-Read Analyst Questions From Charles River Laboratories's Q3 Earnings Call (StockStory)
Nov-06-25 03:58PM	Analyst Report: Charles River Laboratories International, Inc. (Morningstar Research)
12:31AM	CRL Q3 Deep Dive: Portfolio Streamlining and End Market Stabilization Shape Outlook (StockStory)
Nov-05-25 08:15PM	Analyst Report: Charles River Laboratories International, Inc. (Morningstar Research) -5.71%
04:03PM	Charles River Laboratories International Inc (CRL) Q3 2025 Earnings Call Highlights: Strategic ... (GuruFocus.com)
12:26PM	Why Charles River Laboratories (CRL) Shares Are Getting Obliterated Today (StockStory)
09:30AM	Charles River (CRL) Q3 Earnings: How Key Metrics Compare to Wall Street Estimates (Zacks)
09:22AM	CRL's Q3 Earnings Top Estimates, Revenues Decline Y/Y, Stock Falls (Zacks)
08:10AM	Charles River Laboratories (CRL) Q3 Earnings and Revenues Surpass Estimates (Zacks)
07:51AM	Charles River Laboratories's (NYSE:CRL) Q3: Beats On Revenue (StockStory)
07:22AM	Charles River: Q3 Earnings Snapshot (Associated Press Finance)
07:01AM	Charles River Laboratories Provides Update on Strategic Review (Business Wire)
07:00AM	Charles River Laboratories Announces Third-Quarter 2025 Results (Business Wire)
Nov-03-25 10:12PM	What To Expect From Charles River Laboratories's (CRL) Q3 Earnings (StockStory)
Oct-30-25 10:00AM	Solventum (SOLV) Expected to Beat Earnings Estimates: What to Know Ahead of Q3 Release (Zacks)
Oct-29-25 10:00AM	Charles River Laboratories (CRL) Expected to Beat Earnings Estimates: What to Know Ahead of Q3 Release (Zacks)
Oct-27-25 07:17PM	HALPER SADEH LLC ENCOURAGES CHARLES RIVER LABORATORIES INTERNATIONAL, INC. SHAREHOLDERS TO CONTACT THE FIRM TO DISCUSS THEIR RIGHTS (PR Newswire)
Oct-24-25 10:22AM	Halper Sadeh LLC Encourages Charles River Laboratories International, Inc. Shareholders to Contact the Firm to Discuss Their Rights (Business Wire)
08:53AM	Here's How Charles River Stock Is Placed Ahead of Q3 Earnings (Zacks)
Oct-23-25 07:15AM	What to Expect From Charles River Laboratories' Q3 2025 Earnings Report (Barchart)
Oct-22-25 08:00AM	Charles River and the Francis Crick Institute Combine Expertise in Antibody-Drug Conjugate Development (Business Wire)
Oct-20-25 07:22PM	Analyst Report: Charles River Laboratories International, Inc. (Morningstar Research)
12:10PM	Will Charles River (CRL) Beat Estimates Again in Its Next Earnings Report? (Zacks)
08:00AM	Charles River and X-Chem Announce Strategic Collaboration to Enhance Hit Identification Capabilities (Business Wire)
Oct-15-25 08:00AM	Charles River Announces Scientific Advisory Board to Drive Alternative Method Innovation and Adoption (Business Wire)
Oct-14-25 08:00AM	Charles River Laboratories Schedules Third-Quarter 2025 Earnings Release and Conference Call (Business Wire)
12:02AM	3 Reasons to Avoid CRL and 1 Stock to Buy Instead (StockStory)
Oct-10-25 11:50AM	3 Medical Service Industry Stocks Poised to Counter Workforce Issues (Zacks)
Oct-08-25 11:34PM	Winners And Losers Of Q2: Charles River Laboratories (NYSE:CRL) Vs The Rest Of The Drug Development Inputs & Services Stocks (StockStory)
08:00AM	Charles River and Toxys Announce Collaboration to Validate the Use of NAMs for Developmental Toxicity Testing (Business Wire)
Oct-06-25 09:15AM	Pediatrix Medical Group, Inc. (MD) Soars to 52-Week High, Time to Cash Out? (Zacks)
Oct-04-25 08:31AM	Charles River price target raised to $200 from $190 at Evercore ISI (TipRanks)
Oct-03-25 04:16PM	S&P 500 Stocks: These 5 Lead As Index Hits Record High (Investor's Business Daily)
01:05PM	Charles River Laboratories (CRL) Stock Is Up, What You Need To Know (StockStory)
Oct-02-25 11:36AM	Why Charles River Laboratories (CRL) Stock Is Up Today (StockStory)
09:40AM	Nike upgraded, RH downgraded: Wall Street's top analyst calls (The Fly)
09:34AM	Life science tools Q3 preview: Barclays ups Charles River, downgrades Medpace (Investing.com)
Sep-24-25 01:59AM	Is Charles River Laboratories Stock Underperforming the Nasdaq? (Barchart)
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Sep-17-25 08:27AM	Here's Why ClearBridge Investments Growth Strategy Closed Out Charles River Laboratories International (CRL) (Insider Monkey)
Sep-16-25 07:36AM	Insulet names new CFO; Dexcom CEO on leave (MedTech Dive)
07:05AM	Charles River Laboratories Announces Chief Financial Officer Transition (Business Wire)
Sep-12-25 08:44AM	CRL Stock Rises Following New Strategic Oncology Collaborations (Zacks)
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Sep-08-25 08:00AM	Charles River Laboratories to Present at Baird and Morgan Stanley Conferences (Business Wire)
Sep-04-25 08:50AM	Is it the Right Time to Add CRL Stock to Your Portfolio Now? (Zacks)
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Sep-01-25 02:18PM	Podcast: Alternative testing models to shape toxicology with time (Clinical Trials Arena)
10:21AM	Charles River Stock May Benefit From Joining EASYGEN Consortium (Zacks)
Aug-27-25 10:23AM	Charles River Laboratories Stock: Analyst Estimates & Ratings (Barchart)
Aug-26-25 08:00AM	Charles River Joins EASYGEN Consortium, Supports Development of Bedside CAR-T Manufacturing (Business Wire)
Aug-20-25 07:45AM	Factbox-Healthcare firms see growing activist investor involvement in the past year (Reuters)
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Aug-13-25 01:36AM	5 Revealing Analyst Questions From Charles River Laboratories's Q2 Earnings Call (StockStory)
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03:13AM	CRL Q2 Deep Dive: Flat Sales and Margin Pressures Offset by Demand Stabilization and Raised Outlook (StockStory)
Aug-11-25 09:15AM	Interpreting Charles River (CRL) International Revenue Trends (Zacks)
Aug-06-25 10:18PM	Analyst Report: Charles River Laboratories International, Inc. (Morningstar Research) -10.25%
09:30AM	Charles River (CRL) Q2 Earnings: Taking a Look at Key Metrics Versus Estimates (Zacks)
09:24AM	CRL Stock Gains on Q2 Earnings and Revenue Beat, Raises '25 View (Zacks)
08:56AM	Charles River Laboratories (NYSE:CRL) Delivers Impressive Q2 (StockStory)

Charles River Laboratories International, Inc. engages in providing products and services to help pharmaceutical and biotechnology companies. It operates through the following segments: Research Models and Services (RMS), Discovery and Safety Assessment (DSA), and Manufacturing Solutions. The Research Models and Services segment includes its insourcing solutions business and Charles River accelerator and development lab footprint. The Discovery and Safety Assessment segment offers regulatory-required safety testing of potential new drugs, vaccines, industrial and agricultural chemicals, consumer products, veterinary medicines, and medical devices. The Manufacturing Solutions segment focuses on microbial solutions and biologics solutions. The company was founded by Henry L. Foster in 1947 and is headquartered in Wilmington, MA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
LaPlume Joseph W	EVP, Corp Strategy & Develop	Aug 22 '25	Sale	163.72	400	65,488	23,716	Jan 20 08:49 AM
Joseph LaPlume	Officer	Aug 22 '25	Proposed Sale	152.50	400	61,000		Aug 22 01:37 PM
LaPlume Joseph W	EVP, Corp Strategy & Develop	Aug 18 '25	Sale	157.60	800	126,080	24,116	Aug 20 04:45 PM
WALLMAN RICHARD F	Former Director	Aug 18 '25	Proposed Sale	152.00	22,500	3,420,000		Aug 18 05:16 PM
Joseph LaPlume	Officer	Aug 18 '25	Proposed Sale	157.00	800	125,600		Aug 18 01:27 PM
LaPlume Joseph W	EVP, Corp Strategy & Develop	Aug 07 '25	Sale	150.04	400	60,016	24,916	Aug 08 04:18 PM
Joseph LaPlume	Officer	Aug 07 '25	Proposed Sale	150.00	400	60,000		Aug 07 02:57 PM
WALLMAN RICHARD F	Former Director	Jul 21 '25	Proposed Sale	150.00	8,500	1,275,000		Jul 21 04:21 PM
WALLMAN RICHARD F	Former Director	Jun 23 '25	Proposed Sale	137.50	4,000	550,000		Jun 25 04:34 PM
MASSARO GEORGE	Director	May 15 '25	Sale	137.57	140	19,260	5,575	May 16 04:29 PM
MASSARO GEORGE	Director	May 14 '25	Sale	140.73	140	19,703	5,715	May 15 04:41 PM
LaPlume Joseph W	EVP, Corp Strategy & Develop	May 13 '25	Sale	145.41	500	72,705	19,513	May 15 04:38 PM
MASSARO GEORGE	Director	May 14 '25	Proposed Sale	140.73	280	39,405		May 14 04:05 PM
Joseph LaPlume	Officer	May 13 '25	Proposed Sale	144.32	500	72,160		May 13 03:33 PM
FOSTER JAMES C	Chairman, President and CEO	Feb 20 '25	Buy	165.01	6,075	1,002,436	183,639	Feb 21 04:41 PM
Girshick Birgit	Corporate Executive VP & COO	Feb 20 '25	Buy	164.63	1,514	249,250	55,058	Feb 21 04:38 PM
LaPlume Joseph W	EVP, Corp Strategy & Develop	Feb 20 '25	Sale	162.50	4,400	715,000	20,013	Feb 21 04:36 PM
Joseph LaPlume	Officer	Feb 20 '25	Proposed Sale	165.00	4,400	726,000		Feb 20 12:36 PM

PBE Invesco Biotechnology & Genome ETF daily Stock Chart

Category	US Equities - Industry Sector	Asset Type	Equities (Stocks)	Tags	U.S.	Return% 1Y	21.93%	Total Holdings	30	Perf Week	-2.42%
Sponsor	Invesco	ETF Type		Tags	equity	Return% 3Y	7.69%	AUM	261.03M	Perf Month	-0.75%
Fund Family		Bond Type		Tags	biotechnology	Return% 5Y	-0.31%	NAV/sh		Perf Quarter	3.96%
Index	Dynamic Biotechnology & Genome Intellide...	Average Maturity		Tags	-	Return% 10Y		52W High	85.73 -4.88%	Perf Half Y	21.39%
Index Weighting		Commodity Type		Tags	-	Return% SI		52W Low	54.52 49.58%	Perf YTD	-0.73%
Active/Passive		Quant Type		Tags	-	Flows% 1M	0.32%	Volatility	1.09% 1.23%	Perf Year	19.56%
Dividend TTM	0.82 (1.00%)	ESG Type		Tags	-	Flows% 3M	2.01%	ATR (14)	1.13	Perf 3Y	23.88%
Dividend Ex-Date	Dec 22, 2025	Dividend Type		Sector/Theme		Flows% YTD	1.31%	RSI (14)	46.30	Perf 5Y	-0.56%
Dividend Gr. 3/5Y	- 95.02%	Structure Type		Region		Flows% 1Y		Beta	0.76	Perf 10Y	127.35%
Expense	0.58%	Growth/Value		SMA20	-1.11%	Flows% 3Y		Rel Volume	0.52	Prev Close	80.81
Inverse/Leveraged		Market Cap		SMA50	-0.88%	Flows% 5Y		Avg Volume	7.11K	Price	81.55
IPO	Jun 23, 2005	Option/Short	Yes / Yes	SMA200	13.26%	Trades		Volume	3,730	Change	0.92%

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Invesco Dynamic Biotechnology & Genome ETF seeks to track the investment results (before fees and expenses) of the Dynamic Biotech & Genome IntellidexSM Index. The fund generally will invest at least 90% of its total assets in securities that comprise the underlying index. The underlying index was composed of common stocks of U.S. biotechnology and genome companies. These companies are engaged principally in the research, development, manufacture and marketing and distribution of various biotechnological products, services and processes, etc. It is non-diversified.

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CRL

Charles River Laboratories International Inc

PBE

Invesco Biotechnology & Genome ETF

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