VRTX Vertex Pharmaceuticals Incorporated Stock Quote

VRTX [NASD]

Index	S&P 500	P/E	26.00	EPS (ttm)	9.49	Insider Own	0.20%	Shs Outstand	255.10M	Perf Week	-2.84%
Market Cap	61.60B	Forward P/E	16.18	EPS next Y	15.25	Insider Trans	-15.06%	Shs Float	254.81M	Perf Month	-15.20%
Income	2.45B	PEG	2.39	EPS next Q	3.58	Inst Own	93.00%	Short Float	1.34%	Perf Quarter	5.49%
Sales	7.95B	P/S	7.75	EPS this Y	-12.50%	Inst Trans	1.03%	Short Ratio	2.07	Perf Half Y	32.74%
Book/sh	42.76	P/B	5.77	EPS next Y	7.24%	ROA	18.70%	Target Price	293.15	Perf Year	13.65%
Cash/sh	33.00	P/C	7.48	EPS next 5Y	10.90%	ROE	24.70%	52W Range	176.36 - 292.75	Perf YTD	12.35%
Dividend	-	P/FCF	25.13	EPS past 5Y	85.00%	ROI	22.50%	52W High	-13.87%	Beta	0.59
Dividend %	-	Quick Ratio	4.60	Sales past 5Y	34.80%	Gross Margin	88.00%	52W Low	42.97%	ATR	8.90
Employees	3900	Current Ratio	4.80	Sales Q/Q	21.60%	Oper. Margin	36.90%	RSI (14)	45.70	Volatility	3.97% 2.97%
Optionable	Yes	Debt/Eq	0.05	EPS Q/Q	18.50%	Profit Margin	30.80%	Rel Volume	0.59	Prev Close	246.72
Shortable	Yes	LT Debt/Eq	0.05	Earnings	May 05 AMC	Payout	0.00%	Avg Volume	1.65M	Price	252.14
Recom	2.10	SMA20	-4.39%	SMA50	-3.04%	SMA200	15.35%	Volume	368,536	Change	2.20%

May-06-22

Downgrade

Robert W. Baird

Outperform → Neutral

$250

May-03-22

Upgrade

Morgan Stanley

Underweight → Equal-Weight

$250

Feb-03-22

Downgrade

RBC Capital Mkts

Outperform → Sector Perform

$269

Jan-27-22

Reiterated

Wolfe Research

Outperform

$271 → $282

Jan-27-22

Reiterated

Stifel

Hold

$213 → $222

Jan-27-22

Reiterated

RBC Capital Mkts

Outperform

$268 → $269

Jan-27-22

Reiterated

Morgan Stanley

Underweight

$203 → $208

Jan-27-22

Reiterated

JP Morgan

Overweight

$260 → $288

Jan-20-22

Upgrade

BMO Capital Markets

Market Perform → Outperform

$202 → $274

Dec-09-21

Initiated

Wells Fargo

Overweight

$270

Nov-19-21

Initiated

BMO Capital Markets

Market Perform

$202

Nov-19-21

Downgrade

Piper Sandler

Overweight → Neutral

$323 → $218

Sep-09-21

Downgrade

Stifel

Buy → Hold

$244 → $213

Sep-07-21

Downgrade

Morgan Stanley

Equal-Weight → Underweight

$202

Jul-20-21

Downgrade

SVB Leerink

Mkt Perform → Underperform

$170

Jul-19-21

Resumed

Wolfe Research

Outperform

$252

Jul-01-21

Initiated

Raymond James

Mkt Perform

Jun-11-21

Downgrade

Daiwa Securities

Outperform → Neutral

$210

Feb-23-21

Upgrade

Robert W. Baird

Neutral → Outperform

$220 → $252

Feb-02-21

Reiterated

H.C. Wainwright

Buy

$315 → $275

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Apr-20-22 07:04PM	Health Canada Grants Marketing Authorization for TRIKAFTA® (elexacaftor/tezacaftor/ivacaftor and ivacaftor) in Children With Cystic Fibrosis Ages 6 Through 11 years With At Least One F508del Mutation CNW Group
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Apr-16-22 06:18AM	3 Reasons Vertex Pharmaceuticals Is a Top Stock to Buy Now Motley Fool
Apr-14-22 05:50PM	Vertex Pharmaceuticals (VRTX) Stock Moves -1.02%: What You Should Know Zacks

Vertex Pharmaceuticals Incorporated engages in developing and commercializing therapies for treating cystic fibrosis. The company markets SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO to treat patients with cystic fibrosis who have specific mutations in their cystic fibrosis transmembrane conductance regulator gene; and TRIKAFTA for the treatment of patients with CF 12 years of age or older who have at least one F508del mutation in the cystic fibrosis transmembrane conductance regulator, or CFTR, gene. Its pipeline includes Pipeline for Alpha-1 antitrypsin deficiency that is in Phase 2 clinical trial; VX-864, a second investigational small molecule corrector for the treatment of AAT deficiency, which is in Phase 1 clinical trial; and VX-147 that completed a Phase 1 clinical trial for the treatment of APOL1-mediated focal segmental glomerulosclerosis, or FSGS, and other serious kidney diseases. The company sells its products primarily to specialty pharmacy and specialty distributors in the United States, as well as specialty distributors and retail chains, and hospitals and clinics internationally. Vertex Pharmaceuticals Incorporated has collaborations with CRISPR Therapeutics AG; Arbor Biotechnologies, Inc.; Moderna, Inc.; Genomics plc; Merck KGaA; Darmstadt, Germany; X-Chem, Inc.; Janssen Pharmaceuticals, Inc.; Merck KGaA; Kymera Therapeutics; Ribometrix, Inc.; Molecular Templates, Inc.; Mammoth Biosciences; and Affinia Therapeutics, as well as a strategic research collaboration and licensing agreement with Obsidian Therapeutics, Inc. for the discovery of novel therapies that regulate gene editing for the treatment of serious diseases. The company was founded in 1989 and is headquartered in Boston, Massachusetts.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Sanna Bastiano	EVP, Cell & Genetic Therapies	May 04	Sale	275.09	36	9,903	41,660	May 06 04:05 PM
Arbuckle Stuart A	EVP, COO	May 02	Sale	263.98	306	80,778	64,760	May 04 05:21 PM
Sanna Bastiano	EVP, Cell & Genetic Therapies	May 02	Sale	259.16	320	82,930	41,696	May 04 05:10 PM
Bhatia Sangeeta N.	Director	May 02	Sale	258.94	737	190,842	5,903	May 04 05:09 PM
WAGNER CHARLES F JR	EVP & Chief Financial Officer	May 02	Sale	258.83	343	88,778	42,730	May 04 05:07 PM
Liu Joy	SVP, General Counsel	Apr 29	Sale	275.41	120	33,049	14,334	May 03 04:28 PM
Ambrose Kristen	SVP & Chief Accounting Officer	Apr 25	Sale	269.55	327	88,143	3,496	Apr 27 04:05 PM
Lee Yuchun	Director	Apr 18	Option Exercise	81.54	2,000	163,080	3,875	Apr 20 04:05 PM
Lee Yuchun	Director	Apr 18	Sale	284.23	2,000	568,467	1,875	Apr 20 04:05 PM
Lee Yuchun	Director	Apr 14	Option Exercise	81.54	2,000	163,080	3,875	Apr 18 04:05 PM
Lee Yuchun	Director	Apr 14	Sale	289.06	2,000	578,117	1,875	Apr 18 04:05 PM
Lee Yuchun	Director	Apr 13	Option Exercise	81.54	2,000	163,080	3,875	Apr 14 04:35 PM
Lee Yuchun	Director	Apr 13	Sale	287.50	2,000	575,010	1,875	Apr 14 04:35 PM
LEIDEN JEFFREY M	Executive Chairman	Apr 13	Sale	289.04	15,789	4,563,653	74,160	Apr 14 04:35 PM
Lee Yuchun	Director	Apr 12	Option Exercise	81.54	2,000	163,080	3,875	Apr 14 04:35 PM
Lee Yuchun	Director	Apr 12	Sale	281.03	2,000	562,051	1,875	Apr 14 04:35 PM
Lee Yuchun	Director	Apr 11	Option Exercise	81.54	2,000	163,080	3,875	Apr 12 04:07 PM
Lee Yuchun	Director	Apr 11	Sale	280.30	2,000	560,599	1,875	Apr 12 04:07 PM
MCGLYNN MARGARET G	Director	Apr 08	Option Exercise	127.54	5,000	637,700	6,099	Apr 12 04:05 PM
Bhatia Sangeeta N.	Director	Apr 08	Option Exercise	125.71	1,907	239,729	7,098	Apr 12 04:05 PM
Lee Yuchun	Director	Apr 08	Option Exercise	81.54	2,000	163,080	3,875	Apr 12 04:07 PM
Lee Yuchun	Director	Apr 08	Sale	278.57	2,000	557,141	1,875	Apr 12 04:07 PM
Bhatia Sangeeta N.	Director	Apr 08	Sale	280.20	1,907	534,341	5,191	Apr 12 04:05 PM
MCGLYNN MARGARET G	Director	Apr 08	Sale	280.22	5,000	1,401,080	1,099	Apr 12 04:05 PM
Lee Yuchun	Director	Apr 07	Option Exercise	81.54	2,000	163,080	3,875	Apr 08 05:57 PM
Sanna Bastiano	EVP, Cell & Genetic Therapies	Apr 07	Sale	276.18	561	154,935	42,782	Apr 08 04:34 PM
Lee Yuchun	Director	Apr 07	Sale	274.86	2,000	549,720	1,875	Apr 08 05:57 PM
Lee Yuchun	Director	Apr 06	Option Exercise	81.54	2,000	163,080	3,875	Apr 08 05:57 PM
Lee Yuchun	Director	Apr 06	Sale	271.62	2,000	543,243	1,875	Apr 08 05:57 PM
Lee Yuchun	Director	Apr 05	Option Exercise	81.54	2,000	163,080	3,875	Apr 06 04:59 PM
Sanna Bastiano	EVP, Cell & Genetic Therapies	Apr 05	Sale	275.23	3,163	870,552	43,343	Apr 06 05:02 PM
Lee Yuchun	Director	Apr 05	Sale	272.50	2,000	544,993	1,875	Apr 06 04:59 PM
Lee Yuchun	Director	Apr 04	Option Exercise	81.54	2,000	163,080	3,875	Apr 06 04:59 PM
Lee Yuchun	Director	Apr 04	Sale	267.72	2,000	535,431	1,875	Apr 06 04:59 PM
Sanna Bastiano	EVP, Cell & Genetic Therapies	Apr 04	Sale	267.71	562	150,452	46,506	Apr 06 05:02 PM
WAGNER CHARLES F JR	EVP & Chief Financial Officer	Apr 01	Sale	264.76	2,582	683,602	43,620	Apr 05 04:06 PM
MCGLYNN MARGARET G	Director	Mar 31	Option Exercise	127.54	5,000	637,700	6,099	Apr 04 04:05 PM
MCGLYNN MARGARET G	Director	Mar 31	Sale	262.27	5,000	1,311,346	1,099	Apr 04 04:05 PM
Tatsis Ourania	EVP, Chief Reg. & Quality Off.	Mar 17	Sale	250.11	2,833	708,572	47,356	Mar 21 04:15 PM
WAGNER CHARLES F JR	EVP & Chief Financial Officer	Mar 17	Sale	250.15	3,171	793,218	46,202	Mar 21 04:12 PM
Sanna Bastiano	EVP, Cell & Genetic Therapies	Mar 17	Sale	250.06	2,122	530,627	48,412	Mar 21 04:10 PM
Tatsis Ourania	EVP, Chief Reg. & Quality Off.	Feb 25	Sale	230.95	325	75,058	50,189	Feb 28 05:27 PM
Tatsis Ourania	EVP, Chief Reg. & Quality Off.	Feb 18	Sale	231.00	519	119,889	53,104	Feb 22 05:03 PM
ALTSHULER DAVID	EVP, Global Research and CSO	Feb 18	Sale	230.97	4,312	995,949	49,687	Feb 22 04:51 PM
ALTSHULER DAVID	EVP, Global Research and CSO	Feb 14	Sale	232.02	2,444	567,057	57,438	Feb 16 04:05 PM
ALTSHULER DAVID	EVP, Global Research and CSO	Feb 11	Sale	235.02	2,297	539,837	59,882	Feb 14 04:11 PM
ALTSHULER DAVID	EVP, Global Research and CSO	Feb 02	Option Exercise	86.52	4,660	403,183	70,357	Feb 03 04:06 PM
ALTSHULER DAVID	EVP, Global Research and CSO	Feb 02	Sale	251.47	4,660	1,171,842	65,697	Feb 03 04:06 PM
WAGNER CHARLES F JR	EVP & Chief Financial Officer	Feb 02	Sale	250.07	2,944	736,206	57,435	Feb 03 04:29 PM
Sanna Bastiano	EVP, Cell & Genetic Therapies	Feb 02	Sale	250.98	1,040	261,017	54,952	Feb 03 04:26 PM
MCGLYNN MARGARET G	Director	Jan 28	Option Exercise	127.54	5,000	637,700	6,099	Feb 01 04:09 PM
MCGLYNN MARGARET G	Director	Jan 28	Sale	241.79	5,000	1,208,960	1,099	Feb 01 04:09 PM
Sachdev Amit	EVP, Chief Patient Officer	Nov 15	Sale	187.19	51	9,547	31,928	Nov 16 04:07 PM
Arbuckle Stuart A	EVP, COO	Nov 15	Sale	187.26	3	562	41,103	Nov 16 04:05 PM
ALTSHULER DAVID	EVP, Global Research and CSO	Nov 15	Sale	187.22	34	6,365	33,589	Nov 16 04:04 PM
Kewalramani Reshma	CEO & President	Aug 19	Buy	195.65	10,000	1,956,492	73,754	Aug 23 08:30 AM
SACHS BRUCE I	Director	Aug 02	Buy	197.91	15,000	2,968,650	41,210	Aug 04 04:05 PM
Bhatia Sangeeta N.	Director	Jun 02	Sale	209.69	559	117,216	5,191	Jun 04 04:03 PM
Arbuckle Stuart A	EVP, Chief Comm & Ops Officer	May 17	Sale	216.41	109	23,589	41,103	May 19 04:04 PM
ALTSHULER DAVID	EVP, Global Research and CSO	May 17	Sale	216.36	79	17,093	33,589	May 19 04:02 PM
Sanna Bastiano	EVP, Cell & Genetic Therapies	May 17	Sale	216.34	112	24,230	34,108	May 19 04:10 PM
Sachdev Amit	EVP, Chief Patient Officer	May 17	Sale	216.35	45	9,736	40,133	May 19 04:08 PM

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