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GUTS

Fractyl Health Inc

Mar 31 • 04:00PM ET

1.19

Dollar change -0.05
Percentage change -4.03	%

Healthcare • Biotechnology • USA • NASD

Peers: ILMN EXAS CDNA PACB TXG TWST GH CYRX QDEL FLGT

| Held by: VTI IWM VTWO IWO VXF IWN IWC VTWG RSSL VTWV

Index	RUT	P/E	-	EPS (ttm)	-1.46	Insider Own	57.37%	Shs Outstand	48.76M	Perf Week	-8.46%
Market Cap	58.21M	Forward P/E	-	EPS next Y	-1.71	Insider Trans	-0.83%	Shs Float	20.86M	Perf Month	-23.72%
Income	-70.43M	PEG	-	EPS next Q	-0.45	Inst Own	34.80%	Short Float	14.46%	Perf Quarter	-42.23%
Sales	0.09M	P/S	646.82	EPS this Y	12.35%	Inst Trans	-5.34%	Short Ratio	10.14	Perf Half Y	-52.96%
Book/sh	0.58	P/B	2.04	EPS next Y	-20.42%	ROA	-74.55%	Short Interest	3.02M	Perf Year	-83.47%
Cash/sh	1.38	P/C	0.86	EPS next 5Y	18.72%	ROE	-	52W Range	1.16 - 7.89	Perf YTD	-42.23%
Dividend Est.	-	P/FCF	-	EPS past 5Y	-12.32%	ROI	-81.93%	52W High	-84.92%	Beta	0.17
Dividend TTM	-	Quick Ratio	3.63	Sales past 5Y	-4.50%	Gross Margin	-681.72%	52W Low	2.59%	ATR (14)	0.11
Dividend Ex-Date	-	Current Ratio	3.63	EPS Y/Y TTM	-	Oper. Margin	-100570.97%	RSI (14)	36.85	Volatility	7.10% 8.52%
Employees	107	Debt/Eq	2.20	Sales Y/Y TTM	-	Profit Margin	-75732.26%	Recom	1.00	Target Price	8.00
Option/Short	No / Yes	LT Debt/Eq	2.02	EPS Q/Q	90.17%	Payout	-	Rel Volume	0.56	Prev Close	1.24
Sales Surprise	-70.00%	EPS Surprise	-19.54%	Sales Q/Q	-57.14%	Earnings	Mar 03 AMC	Avg Volume	297.53K	Price	1.19
SMA20	-9.92%	SMA50	-21.94%	SMA200	-53.70%	Trades		Volume	166,566	Change	-4.03%

Date	Action	Analyst	Rating Change	Price Target Change
Feb-28-24	Initiated	Evercore ISI	Outperform
Feb-27-24	Initiated	Morgan Stanley	Overweight	$18
Feb-27-24	Initiated	BofA Securities	Buy	$26

Mar-03-25 04:05PM	Fractyl Health Announces Fourth Quarter and Full Year 2024 Financial Results and Business Updates (GlobeNewswire)
Feb-24-25 07:00AM	Fractyl Health to Report Fourth Quarter and Full Year 2024 Financial Results and Provide Business Updates on March 3, 2025 (GlobeNewswire)
Feb-12-25 09:35AM	After Plunging -19.55% in 4 Weeks, Here's Why the Trend Might Reverse for Fractyl Health, Inc. (GUTS) (Zacks)
Feb-10-25 03:00AM	Beyond GLP-1s? This biotech is exploring longer-term metabolic treatments (Pharma Voice)
Jan-31-25 08:01AM	Fractyl Health Announces Increased Focus on Groundbreaking Revita Weight Maintenance and Rejuva Pancreatic Gene Therapy Programs with Potential to Deliver Key Clinical Milestones Across Multiple Studies in 2025 (GlobeNewswire) -5.15%
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Jan-13-25 07:00AM	Fractyl Health Announces Positive Initial Clinical Results Demonstrating Weight Maintenance Following GLP-1 Discontinuation and Revita Procedure in First Patient of the REVEAL-1 Cohort (GlobeNewswire) +5.41%
Jan-06-25 09:10AM	Heres Why Fractyl Health, Inc. (NASDAQ:GUTS) Is Among the Best Diabetes Stocks to Buy Under $10 (Insider Monkey) -6.36%
Dec-12-24 07:00AM	Fractyl Health Unveils Promising Preclinical Data Demonstrating Safety and Feasibility of Local Delivery of RJVA-001 Rejuva Smart GLP-1 Pancreatic Gene Therapy at the World Congress Insulin Resistance, Diabetes and Cardiovascular Disease (WCIRDC) (GlobeNewswire)
Dec-09-24 07:00AM	Fractyl Health to Present New Preclinical Data from its Rejuva Single-Administration Smart GLP-1 Pancreatic Gene Therapy Platform at the World Congress Insulin Resistance, Diabetes and Cardiovascular Disease (WCIRDC) (GlobeNewswire)
Nov-26-24 07:00AM	Fractyl Health to Participate in the Upcoming December Conferences (GlobeNewswire)
Nov-12-24 04:05PM	Fractyl Health Reports Third Quarter 2024 Financial Results and Provides Business Updates (GlobeNewswire)
Nov-04-24 04:05PM	Fractyl Health to Present New Preclinical Data on Sustained Weight Maintenance and Blood Sugar from its Rejuva RJVA-001 Single-Administration GLP-1 Pancreatic Gene Therapy Candidate at ObesityWeek 2024 (GlobeNewswire) -9.86% -6.25%
07:00AM	Fractyl Health Presented New Analysis from Pooled Data of Revita Clinical Studies Demonstrating Durable Weight Loss Maintenance for One Year at ObesityWeek 2024 (GlobeNewswire)
Oct-29-24 07:00AM	Fractyl Health to Report Third Quarter 2024 Financial Results and Provide Business Updates on November 12, 2024 (GlobeNewswire) +23.19%
Oct-28-24 07:00AM	Fractyl Health to Present Compelling Weight Maintenance Data from both Revita and Rejuva Platforms at ObesityWeek 2024 (GlobeNewswire) +16.46%
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Sep-24-24 07:00AM	Fractyl Health to Present at Chardan's 8th Annual Genetic Medicines Conference (GlobeNewswire)
Sep-03-24 07:00AM	Fractyl Health to Participate in Upcoming September Investor Conferences (GlobeNewswire)
Aug-14-24 04:05PM	Fractyl Health Reports Second Quarter 2024 Financial Results and Provides Business Updates (GlobeNewswire) +5.38%
Aug-12-24 10:53AM	Rising diabetes rates spur growth in weight management solutions (Medical Device Network) +14.61%
Aug-08-24 12:13PM	Fractyl Health touts positive year-long weight loss results for Revita device (Clinical Trials Arena) -6.19%
08:00AM	Fractyl Health Announces Clinical Results from German Real-World Registry Showing Meaningful and Sustained Weight Loss for at Least One Year After a Single Revita Endoscopic Procedure (GlobeNewswire)
Aug-07-24 07:00AM	Fractyl Health to Report Second Quarter 2024 Financial Results and Provide Business Updates on August 14, 2024 (GlobeNewswire) -9.77%
Jul-30-24 07:00AM	Fractyl Health Receives FDA Breakthrough Device Designation for Revita in Weight Maintenance for People with Obesity Who Discontinue GLP-1 Based Drugs (GlobeNewswire)
Jun-25-24 09:02AM	FDA expands Fractyl endoscopy trial to include untreated diabetes patients (Medical Device Network) -9.22%
07:00AM	Fractyl Health to Present at Piper Sandler 2nd Annual Virtual Obesity Day (GlobeNewswire)
Jun-24-24 06:00AM	Fractyl Health Announces Advancement in Weight Maintenance Pipeline and Business Updates (GlobeNewswire) +5.76%
Jun-23-24 01:30PM	Fractyl Health Presents New Preclinical Data on Sustained Weight Maintenance and Improved Body Composition from its Rejuva Single-Administration GLP-1 Pancreatic Gene Therapy in President's Select Oral Presentation at the American Diabetes Association's 84th Scientific Sessions (GlobeNewswire)
May-29-24 07:00AM	Fractyl Health to Present New Preclinical Obesity Data from Rejuva Platform at the American Diabetes Association's 84th Scientific Sessions (GlobeNewswire)
May-20-24 06:00AM	Fractyl Health Presents Compelling Preclinical Data from Single-Administration GLP-1 Pancreatic Gene Therapy Rejuva at Digestive Disease Week 2024 (GlobeNewswire)
May-13-24 08:56PM	GUTS Stock Earnings: Fractyl Health Beats EPS for Q1 2024 (InvestorPlace) +8.52%
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04:00PM	Fractyl Health Reports First Quarter 2024 Financial Results and Provides Business Updates (GlobeNewswire)
11:41AM	Fractyl Health Says New Revita Data Show Sustained Weight Loss, Glucose Control in Type 2 Diabetes (MT Newswires)
06:00AM	Fractyl Health Presents Clinical Update on Revita German Real-World Registry for Patients With Advanced Type 2 Diabetes (T2D) (GlobeNewswire)
May-08-24 06:00AM	Fractyl Health to Present at BofA Securities 2024 Health Care Conference (GlobeNewswire)
May-07-24 06:00AM	Fractyl Health to Report First Quarter 2024 Financial Results and Provide Business Updates on May 13, 2024 (GlobeNewswire)
Apr-30-24 08:38AM	Fractyl Health Announces Multiple Presentations at the Upcoming Digestive Disease Week (DDW) 2024 Conference and the German Diabetes Association (DDG) Annual Meeting (GlobeNewswire)
Apr-17-24 03:10PM	The 3 Most Volatile Stocks for Short-Term Traders: April 2024 (InvestorPlace)
Apr-02-24 08:00AM	Fractyl Health Expands Leadership with Appointment of Adrian Kimber as Chief Commercial Officer to Spearhead Anticipated Launch Preparation as the Company Conducts Two Pivotal Studies for Revita in Obesity and Type 2 Diabetes (GlobeNewswire) -9.53%
Apr-01-24 07:00AM	Fractyl Health Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Business Update (GlobeNewswire)
06:00AM	Fractyl Health Receives FDA IDE Approval for the Revita Remain-1 Pivotal Study of Weight Maintenance in Obesity after Discontinuation of GLP-1 Based Drugs (GlobeNewswire)
Mar-12-24 02:06PM	UPDATE -- Fractyl Health Announces New Results From Its Rejuva Platform Demonstrating Potent and Durable Effects of a Single Dose of a Human GLP-1 Pancreatic Gene Therapy Transgene Compared to Semaglutide in the db/db Mouse Model of Diabetes and Obesity (GlobeNewswire) -10.34%
08:38AM	Fractyl Health Announces New Results From Its Rejuva Platform Demonstrating Potent and Durable Effects of a Single Dose of a Human GLP-1 Pancreatic Gene Therapy Transgene Compared to Semaglutide in the db/db Mouse Model of Diabetes and Obesity (GlobeNewswire)
Mar-03-24 01:13PM	Analysts Bet Big on These Beaten-Down IPO Stocks (TipRanks)
Feb-20-24 08:38AM	Fractyl Health Appoints Samuel Conaway to Its Board of Directors, Bolstering New Product Commercial Expertise During Revita Pivotal Clinical Trials (GlobeNewswire)
Feb-01-24 08:08PM	Fractyl Health Announces Pricing of Initial Public Offering (GlobeNewswire)

Fractyl Health, Inc. is a metabolic therapeutics company. It develops medical device solutions for the treatment of metabolic diseases, which includes type 2 diabetes and obesity. The company was founded by Harith Rajagopalan and Jay D. Caplan on August 30, 2010 and is headquartered in Burlington, MA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Royan Ajay	Director	Mar 14 '25	Buy	1.28	17,901	22,980	17,901	Mar 18 07:57 PM
Barnes Kelly Ann	Director	Mar 14 '25	Buy	1.30	31,000	40,210	31,000	Mar 18 04:50 PM
SCHULMAN AMY W	Director	Mar 13 '25	Buy	1.17	8,550	9,964	8,550	Mar 17 05:09 PM
BRADLEY WILLIAM	Director	Mar 13 '25	Buy	1.26	16,129	20,358	16,129	Mar 17 02:57 PM
Conaway Samuel	Director	Mar 13 '25	Buy	1.17	8,550	9,964	8,550	Mar 17 02:56 PM
Rajagopalan Harith	Chief Executive Officer	Jan 31 '25	Option Exercise	1.70	90,972	154,652	582,301	Feb 03 06:04 PM
Rajagopalan Harith	Chief Executive Officer	Jan 30 '25	Option Exercise	1.70	20,948	35,612	512,277	Feb 03 06:04 PM
Rajagopalan Harith	Chief Executive Officer	Jan 31 '25	Sale	1.82	90,972	165,205	491,329	Feb 03 06:04 PM
Rajagopalan Harith	Chief Executive Officer	Jan 30 '25	Sale	1.95	20,948	40,798	491,329	Feb 03 06:04 PM
Caplan Jay David	President, Chief Product Off.	Jan 31 '25	Option Exercise	1.70	22,346	37,988	175,890	Feb 03 06:03 PM
Caplan Jay David	President, Chief Product Off.	Jan 30 '25	Option Exercise	1.70	21,472	36,502	175,016	Feb 03 06:03 PM
Caplan Jay David	President, Chief Product Off.	Jan 30 '25	Sale	1.95	21,472	41,802	153,544	Feb 03 06:03 PM
Caplan Jay David	President, Chief Product Off.	Jan 31 '25	Sale	1.81	22,346	40,464	153,544	Feb 03 06:03 PM
HARITH RAJAGOPALAN	Director	Jan 30 '25	Proposed Sale	2.02	111,920	226,078		Jan 30 04:12 PM
JAY CAPLAN	Officer	Jan 30 '25	Proposed Sale	2.02	43,818	88,512		Jan 30 04:12 PM
Rajagopalan Harith	Chief Executive Officer	Nov 10 '24	Option Exercise	0.00	216,924	0	587,846	Nov 13 06:26 PM
Rajagopalan Harith	Chief Executive Officer	Nov 11 '24	Sale	2.47	96,517	238,358	491,329	Nov 13 06:26 PM
Caplan Jay David	President, Chief Product Off.	Nov 10 '24	Option Exercise	0.00	187,257	0	217,741	Nov 13 06:25 PM
Caplan Jay David	President, Chief Product Off.	Nov 11 '24	Sale	2.47	64,197	158,541	153,544	Nov 13 06:25 PM
Caplan Jay David	President, Chief Product Off.	Sep 12 '24	Option Exercise	1.70	95,484	162,323	95,484	Sep 13 06:39 PM
Caplan Jay David	President, Chief Product Off.	Sep 12 '24	Sale	2.90	65,000	188,474	30,484	Sep 13 06:39 PM
JAY D CAPLAN	Officer	Sep 12 '24	Proposed Sale	2.85	65,000	185,213		Sep 12 04:44 PM

Dollar change +1.56
Percentage change 0.58	%

ALNY Alnylam Pharmaceuticals Inc daily Stock Chart

Peers: VRTX REGN BMRN BIIB IONS SRPT ARWR NTLA CRSP EDIT

| Held by: VTI VO VXF VUG VOT IBB IWP XBI IWR IWF

Index	-	P/E	-	EPS (ttm)	-2.17	Insider Own	4.41%	Shs Outstand	129.29M	Perf Week	-7.11%
Market Cap	35.12B	Forward P/E	189.12	EPS next Y	1.43	Insider Trans	-2.05%	Shs Float	124.34M	Perf Month	9.43%
Income	-278.16M	PEG	-	EPS next Q	-0.93	Inst Own	95.03%	Short Float	2.04%	Perf Quarter	11.35%
Sales	2.25B	P/S	15.62	EPS this Y	18.25%	Inst Trans	-0.26%	Short Ratio	3.29	Perf Half Y	-1.66%
Book/sh	0.52	P/B	520.39	EPS next Y	180.12%	ROA	-6.84%	Short Interest	2.54M	Perf Year	74.89%
Cash/sh	20.72	P/C	13.03	EPS next 5Y	-	ROE	-	52W Range	141.98 - 304.39	Perf YTD	14.75%
Dividend Est.	-	P/FCF	-	EPS past 5Y	23.11%	ROI	-10.47%	52W High	-11.29%	Beta	0.30
Dividend TTM	-	Quick Ratio	2.71	Sales past 5Y	63.53%	Gross Margin	85.62%	52W Low	90.19%	ATR (14)	11.97
Dividend Ex-Date	-	Current Ratio	2.78	EPS Y/Y TTM	38.54%	Oper. Margin	-7.87%	RSI (14)	56.46	Volatility	4.32% 4.44%
Employees	2230	Debt/Eq	40.89	Sales Y/Y TTM	22.97%	Profit Margin	-12.37%	Recom	1.74	Target Price	319.71
Option/Short	Yes / Yes	LT Debt/Eq	38.58	EPS Q/Q	40.90%	Payout	-	Rel Volume	1.38	Prev Close	268.46
Sales Surprise	1.81%	EPS Surprise	-9.78%	Sales Q/Q	34.90%	Earnings	Feb 13 BMO	Avg Volume	771.67K	Price	270.02
SMA20	5.46%	SMA50	3.81%	SMA200	5.42%	Trades		Volume	1,068,173	Change	0.58%

Date	Action	Analyst	Rating Change	Price Target Change
Today	Initiated	Redburn Atlantic	Buy	$353
Mar-24-25	Upgrade	JP Morgan	Neutral → Overweight	$280 → $328
Nov-12-24	Downgrade	Wolfe Research	Peer Perform → Underperform
Oct-16-24	Initiated	Scotiabank	Sector Outperform
Aug-16-24	Upgrade	Goldman	Neutral → Buy	$198 → $370
Feb-16-24	Downgrade	Goldman	Buy → Neutral	$173
Feb-15-24	Initiated	Wolfe Research	Peer Perform
Dec-08-23	Initiated	Wells Fargo	Equal Weight	$171
Dec-08-23	Initiated	Wells Fargo	Equal Weight
Oct-11-23	Downgrade	Oppenheimer	Outperform → Perform
Sep-29-23	Initiated	Raymond James	Outperform	$208
May-05-23	Upgrade	BMO Capital Markets	Market Perform → Outperform	$200 → $250
Apr-26-23	Initiated	SMBC Nikko	Neutral	$220
Mar-21-23	Initiated	Bernstein	Outperform	$243
Jan-18-23	Initiated	Canaccord Genuity	Buy	$310
Sep-09-22	Resumed	Morgan Stanley	Equal-Weight	$222
Jul-13-22	Initiated	Cantor Fitzgerald	Neutral	$175
Jun-27-22	Downgrade	Guggenheim	Buy → Neutral
Jun-07-22	Initiated	William Blair	Outperform
Apr-25-22	Downgrade	Morgan Stanley	Overweight → Equal-Weight	$210 → $178

Show Previous Ratings

Mar-29-25 01:00PM	Alnylam Presents New Data from the HELIOS-B Phase 3 Study of Vutrisiran in Patients with ATTR Amyloidosis with Cardiomyopathy (ATTR-CM) at the American College of Cardiology's Annual Scientific Session 2025 (Business Wire)
Mar-28-25 04:44PM	FDA Approves Qfitlia (fitusiran), the First siRNA (RNAi Therapeutic) for the Treatment of Hemophilia A or B (Business Wire)
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Mar-27-25 11:30AM	Jazz (JAZZ) Down 9.2% Since Last Earnings Report: Can It Rebound? (Zacks)
Mar-26-25 10:02AM	Biotech Stock Roundup: SAVA Dives on Setback, ALNY Up on Update & More (Zacks)
Mar-25-25 07:28AM	Verve Therapeutics: HeFH Treatment Program Of VERVE-102 Remains On Track With 2025 Catalysts (SeekingAlpha)
Mar-24-25 09:57AM	Alnylam (ALNY) Surges 11.8%: Is This an Indication of Further Gains? (Zacks)
Mar-22-25 09:40AM	Alnylam price target raised to $338 from $300 at Scotiabank (TipRanks)
Mar-21-25 07:13PM	Analyst Report: Alnylam Pharmaceuticals, Inc. (Morningstar Research) +11.75%
05:37PM	Alnylam Pharmaceuticals Ready To Go With Its Next Blockbuster (SeekingAlpha)
04:13PM	Alnylam Jumps As A New Approval Sets Up Its Next Battle With Pfizer, BridgeBio (Investor's Business Daily)
02:04PM	Alnylam challenges Pfizer and BridgeBio with FDA nod for ATTR-CM drug (Pharmaceutical Technology)
01:21PM	Alnylam Stock Jumps After the FDA Approves Its Heart Drug (The Wall Street Journal)
12:46PM	Loading…
12:46PM	Alnylam Gets FDA Nod for Expanded Use of Amvuttra in Cardiomyopathy (Zacks)
11:30AM	BioMarin (BMRN) Up 4.2% Since Last Earnings Report: Can It Continue? (Zacks)
10:05AM	Alnylam Heart Drug Approval Sets Up Challenge With Pfizer (Bloomberg)
07:37AM	Alnylam prices heart drug at premium to rivals (BioPharma Dive)
Mar-20-25 06:13PM	Alnylam nabs key additional indication for Amvuttra (SeekingAlpha)
05:54PM	Alnylam Announces FDA Approval of AMVUTTRA (vutrisiran), the First RNAi Therapeutic to Reduce Cardiovascular Death, Hospitalizations and Urgent Heart Failure Visits in Adults with ATTR Amyloidosis with Cardiomyopathy (ATTR-CM) (Business Wire)
01:57PM	Alnylam drug gets long-awaited FDA approval in deadly heart disease (BioPharma Dive)
Mar-11-25 08:00AM	Alnylam to Webcast Presentation at Stifel 2025 Virtual CNS Forum (Business Wire)
Mar-05-25 07:00AM	Alnylam Announces Retirement of Longtime Board Member, Dr. Phillip A. Sharp, Company Co-Founder and Industry Luminary (Business Wire)
Feb-27-25 01:30PM	Q4 2024 Vir Biotechnology Inc Earnings Call (Thomson Reuters StreetEvents)
Feb-25-25 07:00AM	Alnylam Highlights Significant Pipeline Progress and Platform Innovation at R&D Day (Business Wire)
Feb-24-25 07:11PM	Analyst Report: Alnylam Pharmaceuticals, Inc. (Morningstar Research)
12:59PM	Alnylam Pharmaceuticals (ALNY): Among the Oversold Biotech Stocks to Buy Now (Insider Monkey)
Feb-14-25 04:35PM	Analyst Report: Alnylam Pharmaceuticals, Inc. (Morningstar Research)
02:10AM	Alnylam Pharmaceuticals Inc (ALNY) Q4 2024 Earnings Call Highlights: Strong Revenue Growth and ... (GuruFocus.com)
11:26PM	Loading…
Feb-13-25 11:26PM	Q4 2024 Alnylam Pharmaceuticals Inc Earnings Call (Thomson Reuters StreetEvents)
09:30AM	Alnylam (ALNY) Reports Q4 Earnings: What Key Metrics Have to Say (Zacks)
09:15AM	Alnylam Pharmaceuticals (ALNY) Beats Q4 Earnings and Revenue Estimates (Zacks)
08:18AM	Alnylam: Q4 Earnings Snapshot (Associated Press Finance)
08:00AM	Alnylam Pharmaceuticals Reports Fourth Quarter and Full Year 2024 Financial Results and Highlights Recent Period Progress (Business Wire)
Feb-10-25 09:16AM	Ahead of Alnylam (ALNY) Q4 Earnings: Get Ready With Wall Street Estimates for Key Metrics (Zacks)
Feb-06-25 10:01AM	Alnylam Pharmaceuticals (ALNY) May Report Negative Earnings: Know the Trend Ahead of Next Week's Release (Zacks)
Jan-30-25 08:00AM	Alnylam to Webcast Conference Call Discussing Fourth Quarter and Full Year 2024 Financial Results (Business Wire)
Jan-23-25 09:50AM	Here's Why Alnylam Pharmaceuticals (ALNY) is a Strong Momentum Stock (Zacks)
Jan-21-25 07:20PM	Analyst Report: Alnylam Pharmaceuticals, Inc. (Morningstar Research) +7.60%
09:40AM	Are Medical Stocks Lagging Alnylam Pharmaceuticals (ALNY) This Year? (Zacks)
Jan-12-25 04:00PM	Alnylam Announces Preliminary* Fourth Quarter and Full Year 2024 Global Net Product Revenues and Provides 2025 Combined Net Product Revenue Guidance and Pipeline Goals (Business Wire)
Jan-06-25 08:00AM	Alnylam to Webcast Presentation at 43rd Annual J.P. Morgan Healthcare Conference (Business Wire)
Dec-25-24 09:40AM	Is Alnylam Pharmaceuticals (ALNY) Stock Outpacing Its Medical Peers This Year? (Zacks)
Dec-23-24 10:09AM	Is Alnylam Pharmaceuticals, Inc. (ALNY) the Best Performing Biotech Stock in 2024? (Insider Monkey)
Dec-04-24 12:00PM	What Makes Alnylam (ALNY) a New Buy Stock (Zacks)
Dec-02-24 02:48PM	Why Is Alnylam Pharmaceuticals, Inc. (ALNY) Among the Best High Growth Healthcare Stocks to Invest In Now? (Insider Monkey)
Nov-27-24 07:00AM	Alnylam to Webcast Presentation at Piper Sandler 36th Annual Healthcare Conference (Business Wire)
05:38AM	Kronos, Idorsia plan layoffs; PTC shelves ALS drug (BioPharma Dive)
Nov-25-24 04:16PM	BridgeBio Catapults After Snagging Approval For Its Rival To Pfizer's Heart Drug (Investor's Business Daily)
07:00AM	Alnylam Announces U.S. Food and Drug Administration Acceptance of Supplemental New Drug Application for Vutrisiran for the Treatment of ATTR Amyloidosis with Cardiomyopathy (Business Wire)
Nov-22-24 02:16PM	BridgeBio heart drug approved by FDA, setting up battle with Pfizer (BioPharma Dive)
Nov-18-24 07:24AM	Alnylam reveals trial outcomes of nucresiran for ATTR amyloidosis treatment (Clinical Trials Arena)
Nov-17-24 09:30AM	Alnylam Announces Interim Phase 1 Data of Nucresiran (ALN-TTRsc04) Showing Rapid Knockdown of TTR that is Sustained at Six Months Following a Single Dose (Business Wire)
Nov-15-24 07:19PM	Analyst Report: Alnylam Pharmaceuticals, Inc. (Morningstar Research) -8.67%
Nov-06-24 12:26PM	Top 20 biopharmas market cap rises 2% in Q3 2024 amid flurry of drug approvals (Pharmaceutical Technology)
04:27AM	An RNAi renaissance is creating a new generation of startups (BioPharma Dive)
Nov-04-24 08:00AM	Alnylam to Webcast Presentations at Upcoming November Investor Conferences (Business Wire)
Nov-01-24 10:34AM	Analyst Report: Alnylam Pharmaceuticals, Inc. (Morningstar Research)
03:05AM	Alnylam Pharmaceuticals Inc (ALNY) Q3 2024 Earnings Call Highlights: Strong Revenue Growth and ... (GuruFocus.com)
01:11AM	Decoding Alnylam Pharmaceuticals Inc (ALNY): A Strategic SWOT Insight (GuruFocus.com)
12:25AM	Q3 2024 Alnylam Pharmaceuticals Inc Earnings Call (Thomson Reuters StreetEvents)
Oct-31-24 10:00AM	Alnylam (ALNY) Reports Q3 Earnings: What Key Metrics Have to Say (Zacks) -5.29%
09:10AM	Alnylam Pharmaceuticals (ALNY) Reports Q3 Loss, Lags Revenue Estimates (Zacks)
08:07AM	Alnylam: Q3 Earnings Snapshot (Associated Press Finance)
08:00AM	Alnylam Pharmaceuticals Reports Third Quarter 2024 Financial Results and Highlights Recent Period Activity (Business Wire)
Oct-30-24 11:31AM	Cognizant signs deal to enhance Alnylams IT infrastructure (Verdict)
08:00AM	Alnylam to Showcase Latest Data from TTR Franchise and Hypertension Program at American Heart Association Scientific Sessions 2024 (Business Wire)
Oct-28-24 09:16AM	Seeking Clues to Alnylam (ALNY) Q3 Earnings? A Peek Into Wall Street Projections for Key Metrics (Zacks)
Oct-24-24 10:01AM	Alnylam Pharmaceuticals (ALNY) Expected to Beat Earnings Estimates: Should You Buy? (Zacks)
Oct-23-24 12:00PM	Alnylam Pharmaceuticals (ALNY) is a Great Momentum Stock: Should You Buy? (Zacks)
Oct-17-24 09:40AM	Are Medical Stocks Lagging Alnylam Pharmaceuticals (ALNY) This Year? (Zacks)
08:00AM	Alnylam to Webcast Conference Call Discussing Third Quarter 2024 Financial Results (Business Wire)
Oct-16-24 08:00AM	Alnylam Submits Regulatory Application to the European Medicines Agency for Vutrisiran for the Treatment of ATTR Amyloidosis with Cardiomyopathy (Business Wire)
Oct-09-24 12:14PM	Biotech Eyes Early Entry As Several Factors Could Unleash Shares (Investor's Business Daily)
07:00AM	Protein prediction wins chemistry Nobel; Alnylam submits an all-important drug application (BioPharma Dive)
07:00AM	Alnylam Submits Supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration for Vutrisiran for the Treatment of Transthyretin Amyloidosis with Cardiomyopathy (Business Wire)
Oct-08-24 07:41AM	Startup led by John Maraganore raises $135M to build future of RNAi (BioPharma Dive)
Oct-07-24 03:00AM	Judo Bio debuts with $100M and a plan to take RNA drugs to the kidney (BioPharma Dive)
Oct-01-24 09:40AM	Is Alnylam Pharmaceuticals (ALNY) Stock Outpacing Its Medical Peers This Year? (Zacks)
08:03AM	Not Holding Alnylam Pharmaceuticals (ALNY) Hurt Fidelity Growth Strategies Funds Performance (Insider Monkey)
Sep-29-24 09:00AM	Alnylam Highlights New Data From HELIOS-B Study of Vutrisiran for the Treatment of Transthyretin Amyloidosis With Cardiomyopathy at Heart Failure Society of America Annual Scientific Meeting 2024 (Business Wire)
Sep-26-24 08:00AM	Alnylam to Webcast TTR Investor Day (Business Wire)
Sep-14-24 07:03PM	Alnylam Pharmaceuticals, Inc. (ALNY): Hedge Funds Are Bullish on This Aggressive Growth Stock (Insider Monkey)
Sep-13-24 07:10PM	Analyst Report: Alnylam Pharmaceuticals, Inc. (Morningstar Research)
Sep-12-24 01:01PM	The Brawl Taking Shape Over Pfizers Multibillion-Dollar Heart Monopoly (The Wall Street Journal)
Sep-08-24 02:01AM	Alnylam Pharmaceuticals, Inc. (ALNY): Do Hedge Funds Recommend This Biotech Stock Now? (Insider Monkey)
Sep-06-24 07:09PM	Analyst Report: Alnylam Pharmaceuticals, Inc. (Morningstar Research)
Aug-30-24 04:19PM	Why IBD 50's Alnylam Just Reversed Its 50% Gain And BridgeBio Surged (Investor's Business Daily) -8.47%
04:03PM	Alnylam Stock Falls on Positive but Disappointing Study Results for Heart Drug (The Wall Street Journal)
02:33PM	ESC Congress: Amvuttra data signals positive prospects in cardiomyopathy for Alnylam (Pharmaceutical Technology)
02:33PM	ESC 2024: Amvuttra data signals positive prospects in cardiomyopathy for Alnylam (Pharmaceutical Technology)
10:13AM	Alnylam Plummets, Reversing 50% Gain This Year, As Pfizer Rival Lags Expectations (Investor's Business Daily)
06:00AM	Alnylam Presents Detailed Results from the Positive HELIOS-B Phase 3 Study of Vutrisiran? in Patients with ATTR Amyloidosis with Cardiomyopathy at the European Society of Cardiology Congress (Business Wire)
02:00AM	Full study data back Alnylam heart drugs benefit, but leave doctors with tough choices (BioPharma Dive)
Aug-28-24 04:00PM	Alnylam to Webcast Presentations at Upcoming September Investor Conferences (Business Wire)
Aug-23-24 10:22AM	Alnylam (ALNY) Amvuttra & Givlaari Fuel Revenues Amid Competition (Zacks)
Aug-21-24 02:45AM	Here's Why Alnylam Pharmaceuticals (ALNY) Surged in Q2 (Insider Monkey)
Aug-07-24 09:00AM	The 3 Best Gene Editing Stocks to Buy in August 2024 (InvestorPlace)
08:00AM	Alnylam to Present Detailed Results from the HELIOS-B Phase 3 Study of Vutrisiran in Patients with ATTR Amyloidosis with Cardiomyopathy at the European Society of Cardiology Congress 2024 (Business Wire)

Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company. It engages in the business of developing and commercializing novel therapeutics based on ribonucleic acid interference. The company was founded by Noble Laureate, David Bartel, Thomas Tuschl, Phillip Zamore, Paul R. Schimmel, and Phillip Allen Sharp on June 14, 2002 and is headquartered in Cambridge, MA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Garg Pushkal	CMO & EVP Dev & Med Affairs	Mar 24 '25	Option Exercise	42.22	5,445	229,888	25,666	Mar 25 04:10 PM
Garg Pushkal	CMO & EVP Dev & Med Affairs	Mar 24 '25	Sale	300.00	5,445	1,633,500	20,221	Mar 25 04:10 PM
Garg Pushkal	CMO & EVP Dev & Med Affairs	Mar 21 '25	Sale	285.00	4,321	1,231,485	20,221	Mar 25 04:10 PM
PYOTT DAVID E I	Director	Mar 24 '25	Option Exercise	88.95	7,440	661,788	7,576	Mar 25 04:09 PM
PYOTT DAVID E I	Director	Mar 24 '25	Sale	299.00	7,440	2,224,560	136	Mar 25 04:09 PM
PYOTT DAVID E I	Director	Mar 24 '25	Proposed Sale	299.00	7,440	2,224,560		Mar 24 04:13 PM
Garg Pushkal	Officer	Mar 24 '25	Proposed Sale	300.00	5,445	1,633,500		Mar 24 04:06 PM
Garg Pushkal	Officer	Mar 21 '25	Proposed Sale	285.00	4,321	1,231,485		Mar 21 04:03 PM
SCHULMAN AMY W	Director	Mar 13 '25	Option Exercise	131.21	2,750	360,828	11,186	Mar 14 04:16 PM
Fitzgerald Kevin Joseph	CSO & EVP, Head of Research	Mar 03 '25	Sale	243.73	1,911	465,772	14,345	Mar 05 04:22 PM
Fitzgerald Kevin Joseph	CSO & EVP, Head of Research	Mar 04 '25	Sale	241.15	844	203,532	13,501	Mar 05 04:22 PM
Tanguler Tolga	EVP, Chief Commercial Officer	Mar 03 '25	Sale	243.78	471	114,820	28,011	Mar 05 04:22 PM
Garg Pushkal	CMO & EVP Dev & Med Affairs	Mar 03 '25	Sale	243.79	1,749	426,384	25,350	Mar 05 04:21 PM
Garg Pushkal	CMO & EVP Dev & Med Affairs	Mar 04 '25	Sale	241.05	808	194,766	24,542	Mar 05 04:21 PM
Poulton Jeffrey V.	EVP, Chief Financial Officer	Mar 03 '25	Sale	243.78	1,264	308,141	47,751	Mar 05 04:21 PM
Greenstreet Yvonne	Chief Executive Officer	Mar 03 '25	Sale	243.79	3,877	945,165	98,635	Mar 05 04:20 PM
Fitzgerald Kevin Joseph	Officer	Mar 04 '25	Proposed Sale	241.09	844	203,479		Mar 04 04:07 PM
Garg Pushkal	Officer	Mar 04 '25	Proposed Sale	241.09	808	194,801		Mar 04 04:06 PM
Greenstreet Yvonne	Chief Executive Officer	Feb 27 '25	Option Exercise	0.00	5,921	0	87,447	Mar 03 04:32 PM
Greenstreet Yvonne	Chief Executive Officer	Feb 28 '25	Sale	241.69	2,900	700,894	84,547	Mar 03 04:32 PM
Poulton Jeffrey V.	EVP, Chief Financial Officer	Feb 27 '25	Option Exercise	0.00	1,908	0	34,694	Mar 03 04:31 PM
Poulton Jeffrey V.	EVP, Chief Financial Officer	Feb 28 '25	Sale	241.70	796	192,390	33,898	Mar 03 04:31 PM
Tanguler Tolga	EVP, Chief Commercial Officer	Feb 27 '25	Option Exercise	0.00	1,667	0	14,858	Mar 03 04:31 PM
Tanguler Tolga	EVP, Chief Commercial Officer	Feb 28 '25	Sale	241.68	513	123,983	14,345	Mar 03 04:31 PM
Garg Pushkal	CMO & EVP Dev & Med Affairs	Feb 27 '25	Option Exercise	0.00	1,908	0	13,897	Mar 03 04:31 PM
Garg Pushkal	CMO & EVP Dev & Med Affairs	Feb 28 '25	Sale	241.69	935	225,977	12,962	Mar 03 04:31 PM
Fitzgerald Kevin Joseph	CSO & EVP, Head of Research	Feb 28 '25	Sale	241.69	496	119,878	12,385	Mar 03 04:30 PM
Garg Pushkal	Officer	Mar 03 '25	Proposed Sale	246.18	973	239,533		Mar 03 04:09 PM
Fitzgerald Kevin Joseph	Officer	Mar 03 '25	Proposed Sale	246.18	1,171	288,277		Mar 03 04:09 PM
Greenstreet Yvonne	Chief Executive Officer	Feb 14 '25	Sale	255.17	1,213	309,527	81,526	Feb 18 04:49 PM
Poulton Jeffrey V.	EVP, Chief Financial Officer	Feb 14 '25	Sale	255.17	967	246,750	32,786	Feb 18 04:47 PM
Fitzgerald Kevin Joseph	CSO & EVP, Head of Research	Feb 18 '25	Sale	251.56	1,440	362,243	12,881	Feb 18 04:47 PM
Fitzgerald Kevin Joseph	CSO & EVP, Head of Research	Feb 14 '25	Sale	255.21	663	169,204	14,321	Feb 18 04:47 PM
Garg Pushkal	CMO & EVP Dev & Med Affairs	Feb 14 '25	Sale	255.17	1,561	398,325	13,537	Feb 18 04:47 PM
Garg Pushkal	CMO & EVP Dev & Med Affairs	Feb 18 '25	Sale	251.67	1,548	389,579	11,989	Feb 18 04:47 PM
Garg Pushkal	Officer	Feb 18 '25	Proposed Sale	256.95	1,548	397,759		Feb 18 04:14 PM
Fitzgerald Kevin Joseph	Officer	Feb 18 '25	Proposed Sale	256.95	1,440	370,008		Feb 18 04:13 PM
Garg Pushkal	CMO & EVP Dev & Med Affairs	Jan 27 '25	Option Exercise	88.95	48,876	4,347,520	64,581	Jan 29 04:03 PM
Garg Pushkal	CMO & EVP Dev & Med Affairs	Jan 27 '25	Sale	285.00	52,592	14,988,720	11,989	Jan 29 04:03 PM
Garg Pushkal	Officer	Jan 27 '25	Proposed Sale	285.00	52,592	14,988,720		Jan 27 04:01 PM
SHARP PHILLIP A	Director	Jan 23 '25	Option Exercise	131.21	11,250	1,476,112	11,250	Jan 24 04:10 PM
SHARP PHILLIP A	Director	Jan 23 '25	Sale	275.00	11,250	3,093,750	0	Jan 24 04:10 PM
SHARP PHILLIP A	Director	Jan 23 '25	Proposed Sale	275.00	11,250	3,093,750		Jan 23 04:17 PM
Garg Pushkal	CMO & EVP Dev & Med Affairs	Dec 12 '24	Sale	251.00	1,752	439,760	15,705	Dec 13 04:13 PM
Garg Pushkal	Officer	Dec 12 '24	Proposed Sale	255.02	1,752	446,795		Dec 12 04:05 PM
Greenstreet Yvonne	Chief Executive Officer	Nov 26 '24	Sale	250.98	5,219	1,309,853	78,880	Nov 27 05:22 PM
Garg Pushkal	CMO & EVP Dev & Med Affairs	Nov 26 '24	Sale	250.98	1,682	422,144	17,457	Nov 27 05:22 PM
Poulton Jeffrey V.	EVP, Chief Financial Officer	Nov 26 '24	Sale	250.98	1,682	422,144	30,644	Nov 27 05:21 PM
Tanguler Tolga	EVP, Chief Commercial Officer	Nov 26 '24	Sale	250.98	1,469	368,686	13,191	Nov 27 05:21 PM
Fitzgerald Kevin Joseph	CSO & EVP, Head of Research	Nov 27 '24	Sale	252.29	1,531	386,261	12,881	Nov 27 05:20 PM
Fitzgerald Kevin Joseph	CSO & EVP, Head of Research	Nov 26 '24	Sale	250.98	1,469	368,686	14,412	Nov 27 05:20 PM
Fitzgerald Kevin Joseph	Officer	Nov 27 '24	Proposed Sale	253.98	1,531	388,843		Nov 27 04:06 PM
Greenstreet Yvonne	Chief Executive Officer	Aug 20 '24	Option Exercise	85.00	15,000	1,275,000	88,441	Aug 22 08:01 PM
Greenstreet Yvonne	Chief Executive Officer	Aug 20 '24	Sale	280.00	15,000	4,200,000	73,441	Aug 22 08:01 PM
Greenstreet Yvonne	Officer	Aug 20 '24	Proposed Sale	280.00	15,000	4,200,000		Aug 20 05:10 PM
Fitzgerald Kevin Joseph	CSO & EVP, Head of Research	Aug 12 '24	Option Exercise	89.09	20,725	1,846,429	34,906	Aug 14 04:12 PM
Fitzgerald Kevin Joseph	CSO & EVP, Head of Research	Aug 12 '24	Sale	270.99	22,025	5,968,516	12,881	Aug 14 04:12 PM
Fitzgerald Kevin Joseph	Officer	Aug 12 '24	Proposed Sale	269.52	22,025	5,936,178		Aug 12 04:07 PM
Ausiello Dennis A	Director	Aug 06 '24	Option Exercise	119.68	20,250	2,423,452	20,386	Aug 08 04:10 PM
Ausiello Dennis A	Director	Aug 06 '24	Sale	262.00	20,250	5,305,586	136	Aug 08 04:10 PM
Ausiello Dennis A	Director	Aug 06 '24	Proposed Sale	266.66	20,250	5,399,865		Aug 06 04:07 PM
Greenstreet Yvonne	Chief Executive Officer	Aug 01 '24	Option Exercise	85.00	15,148	1,287,580	88,589	Aug 02 08:01 PM
Greenstreet Yvonne	Chief Executive Officer	Aug 01 '24	Sale	270.00	15,148	4,089,960	73,441	Aug 02 08:01 PM
Greenstreet Yvonne	Officer	Aug 01 '24	Proposed Sale	270.00	15,148	4,089,960		Aug 01 04:01 PM
Greenstreet Yvonne	Chief Executive Officer	Jul 11 '24	Sale	261.00	7,093	1,851,273	73,441	Jul 12 08:02 PM
SCHULMAN AMY W	Director	Jun 25 '24	Option Exercise	131.21	8,500	1,115,285	16,936	Jun 27 04:04 PM
SCHULMAN AMY W	Director	Jun 25 '24	Sale	240.00	8,500	2,040,000	8,436	Jun 27 04:04 PM
PYOTT DAVID E I	Director	Jun 24 '24	Option Exercise	80.76	32,450	2,620,611	32,586	Jun 26 04:28 PM
PYOTT DAVID E I	Director	Jun 24 '24	Sale	220.69	32,450	7,161,360	136	Jun 26 04:28 PM
Garg Pushkal	CMO & EVP Dev & Med Affairs	Jun 25 '24	Sale	230.99	2,103	485,773	15,609	Jun 26 04:28 PM
Greenstreet Yvonne	Chief Executive Officer	Jun 25 '24	Sale	230.99	8,301	1,917,475	80,534	Jun 26 04:27 PM
Poulton Jeffrey V.	EVP, Chief Financial Officer	Jun 25 '24	Sale	231.00	1,605	370,747	28,892	Jun 26 04:26 PM
Tanguler Tolga	EVP, Chief Commercial Officer	Jun 25 '24	Sale	231.00	1,605	370,747	11,660	Jun 26 04:26 PM
Fitzgerald Kevin Joseph	CSO & EVP, Head of Research	Jun 25 '24	Sale	230.99	1,198	276,731	14,181	Jun 26 04:26 PM
SCHULMAN AMY W	Director	May 29 '24	Option Exercise	66.83	30,000	2,004,900	30,136	May 31 07:00 PM
SCHULMAN AMY W	Director	May 29 '24	Sale	148.60	21,700	3,224,546	8,436	May 31 07:00 PM

GUTS

Fractyl Health Inc

ALNY

Alnylam Pharmaceuticals Inc

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